scaffold Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
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Genes

355 genes co-occuring with the biological term scaffold in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
A2M alpha-2-macroglobulin
ACTR2 ARP2 actin-related protein 2 homolog (yeast)
ACTR3 ARP3 actin-related protein 3 homolog (yeast)
ADAP1 ArfGAP with dual PH domains 1
ADRB1 adrenoceptor beta 1
ADRBK1 adrenergic, beta, receptor kinase 1
AFF4 AF4/FMR2 family, member 4
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AICDA activation-induced cytidine deaminase
AKAP10 A kinase (PRKA) anchor protein 10
AKAP12 A kinase (PRKA) anchor protein 12
AKAP13 A kinase (PRKA) anchor protein 13
AKAP5 A kinase (PRKA) anchor protein 5
AKAP6 A kinase (PRKA) anchor protein 6
AKAP8 A kinase (PRKA) anchor protein 8
AKAP8L A kinase (PRKA) anchor protein 8-like
AKT1 v-akt murine thymoma viral oncogene homolog 1
ALK anaplastic lymphoma receptor tyrosine kinase
ALOX5 arachidonate 5-lipoxygenase
AMER1 APC membrane recruitment protein 1
AMOT angiomotin
AMOTL1 angiomotin like 1
AMOTL2 angiomotin like 2
ANXA2 annexin A2
ANXA6 annexin A6
AP5B1 adaptor-related protein complex 5, beta 1 subunit
APBB1 amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
APOBEC3F apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3F
APOBEC3G apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G
APP amyloid beta (A4) precursor protein
APPL1 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1
AR androgen receptor
ARF6 ADP-ribosylation factor 6
ARHGAP8 Rho GTPase activating protein 8
ARRB1 arrestin, beta 1
ARRB2 arrestin, beta 2
ATF2 activating transcription factor 2
ATMIN ATM interactor
AURKA aurora kinase A
AXIN1 axin 1
AXL AXL receptor tyrosine kinase
BANP BTG3 associated nuclear protein
BDNF brain-derived neurotrophic factor
BMP2 bone morphogenetic protein 2
BMP4 bone morphogenetic protein 4
BOLA3 bolA family member 3
BRCA1 breast cancer 1, early onset
BRCC3 BRCA1/BRCA2-containing complex, subunit 3
BTBD1 BTB (POZ) domain containing 1
BTBD2 BTB (POZ) domain containing 2
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase
CAPN3 calpain 3, (p94)
CASP3 caspase 3, apoptosis-related cysteine peptidase
CAV1 caveolin 1, caveolae protein, 22kDa
CC2D1A coiled-coil and C2 domain containing 1A
CCDC69 coiled-coil domain containing 69
CCND1 cyclin D1
CD38 CD38 molecule
CD9 CD9 molecule
CDC42 cell division cycle 42
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDK1 cyclin-dependent kinase 1
CFL1 cofilin 1 (non-muscle)
CHEK2 checkpoint kinase 2
CHRM1 cholinergic receptor, muscarinic 1
CHRM3 cholinergic receptor, muscarinic 3
CHRNA4 cholinergic receptor, nicotinic, alpha 4 (neuronal)
CIAPIN1 cytokine induced apoptosis inhibitor 1
CLEC7A C-type lectin domain family 7, member A
CNKSR1 connector enhancer of kinase suppressor of Ras 1
CNKSR3 CNKSR family member 3
COASY CoA synthase
COMMD1 copper metabolism (Murr1) domain containing 1
COTL1 coactosin-like F-actin binding protein 1
CRTC2 CREB regulated transcription coactivator 2
CSNK1E casein kinase 1, epsilon
CSNK2A1 casein kinase 2, alpha 1 polypeptide
CTNNAL1 catenin (cadherin-associated protein), alpha-like 1
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CTTN cortactin
CUL1 cullin 1
CXCL12 chemokine (C-X-C motif) ligand 12
CXCR2 chemokine (C-X-C motif) receptor 2
CYTH2 cytohesin 2
DAB2IP DAB2 interacting protein
DAPK1 death-associated protein kinase 1
DAXX death-domain associated protein
DCP1A decapping mRNA 1A
DCP2 decapping mRNA 2
DDB1 damage-specific DNA binding protein 1, 127kDa
DDX3X DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked
DISC1 disrupted in schizophrenia 1
DLG1 discs, large homolog 1 (Drosophila)
DSG1 desmoglein 1
DYRK1A dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A
DYRK2 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2
EBNA1BP2 EBNA1 binding protein 2
EDC4 enhancer of mRNA decapping 4
EGFR epidermal growth factor receptor
EGLN1 egl-9 family hypoxia-inducible factor 1
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1
ELK1 ELK1, member of ETS oncogene family
ELMO2 engulfment and cell motility 2
EP300 E1A binding protein p300
EPM2A epilepsy, progressive myoclonus type 2A, Lafora disease (laforin)
ERBB2 erb-b2 receptor tyrosine kinase 2
ERCC1 excision repair cross-complementation group 1
ERCC4 excision repair cross-complementation group 4
ERLEC1 endoplasmic reticulum lectin 1
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2
EVPL envoplakin
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit
F11R F11 receptor
F2RL2 coagulation factor II (thrombin) receptor-like 2
FAF1 Fas (TNFRSF6) associated factor 1
FBLN5 fibulin 5
FBN1 fibrillin 1
FGFR2 fibroblast growth factor receptor 2
FLNA filamin A, alpha
FLNB filamin B, beta
FLT4 fms-related tyrosine kinase 4
FOS FBJ murine osteosarcoma viral oncogene homolog
FOXO4 forkhead box O4
FUS FUS RNA binding protein
FXN frataxin
FYB FYN binding protein
GAB1 GRB2-associated binding protein 1
GABBR2 gamma-aminobutyric acid (GABA) B receptor, 2
GCK glucokinase (hexokinase 4)
GCKR glucokinase (hexokinase 4) regulator
GEMIN5 gem (nuclear organelle) associated protein 5
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GLRX2 glutaredoxin 2
GNAQ guanine nucleotide binding protein (G protein), q polypeptide
GNB2L1 guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1
GPHN gephyrin
GRIPAP1 GRIP1 associated protein 1
HDAC3 histone deacetylase 3
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HNF1A HNF1 homeobox A
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)
HOTAIR HOX transcript antisense RNA
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
HTT huntingtin
HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase
IAPP islet amyloid polypeptide
IFNAR2 interferon (alpha, beta and omega) receptor 2
IFNB1 interferon, beta 1, fibroblast
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
INADL InaD-like (Drosophila)
IQGAP1 IQ motif containing GTPase activating protein 1
IRF3 interferon regulatory factor 3
IRF8 interferon regulatory factor 8
IRS1 insulin receptor substrate 1
ISCU iron-sulfur cluster assembly enzyme
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2
KCNQ1 potassium channel, voltage gated KQT-like subfamily Q, member 1
KDM1A lysine (K)-specific demethylase 1A
KHDRBS1 KH domain containing, RNA binding, signal transduction associated 1
KSR1 kinase suppressor of ras 1
KSR2 kinase suppressor of ras 2
LAMTOR1 late endosomal/lysosomal adaptor, MAPK and MTOR activator 1
LAMTOR3 late endosomal/lysosomal adaptor, MAPK and MTOR activator 3
LARGE like-glycosyltransferase
LIMD1 LIM domains containing 1
LIMK1 LIM domain kinase 1
LNX1 ligand of numb-protein X 1, E3 ubiquitin protein ligase
LOR loricrin
LRP5 low density lipoprotein receptor-related protein 5
LRP6 low density lipoprotein receptor-related protein 6
LSP1 lymphocyte-specific protein 1
MAP2K2 mitogen-activated protein kinase kinase 2
MAP2K4 mitogen-activated protein kinase kinase 4
MAP2K7 mitogen-activated protein kinase kinase 7
MAP3K11 mitogen-activated protein kinase kinase kinase 11
MAP3K5 mitogen-activated protein kinase kinase kinase 5
MAP3K7 mitogen-activated protein kinase kinase kinase 7
MAPK1 mitogen-activated protein kinase 1
MAPK10 mitogen-activated protein kinase 10
MAPK3 mitogen-activated protein kinase 3
MAPK8 mitogen-activated protein kinase 8
MAPK8IP1 mitogen-activated protein kinase 8 interacting protein 1
MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3
MAPKAP1 mitogen-activated protein kinase associated protein 1
MAPT microtubule-associated protein tau
MAT2B methionine adenosyltransferase II, beta
MCC mutated in colorectal cancers
MCM10 minichromosome maintenance complex component 10
MCM2 minichromosome maintenance complex component 2
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MEF2A myocyte enhancer factor 2A
MEN1 multiple endocrine neoplasia I
MET MET proto-oncogene, receptor tyrosine kinase
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1
MIR210 microRNA 210
MPO myeloperoxidase
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MTSS1 metastasis suppressor 1
MVP major vault protein
MYD88 myeloid differentiation primary response 88
NALCN sodium leak channel, non selective
NBN nibrin
NCK1 NCK adaptor protein 1
NCSTN nicastrin
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
NEK2 NIMA-related kinase 2
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NFU1 NFU1 iron-sulfur cluster scaffold
NHLRC1 NHL repeat containing E3 ubiquitin protein ligase 1
NLK nemo-like kinase
NLRP10 NLR family, pyrin domain containing 10
NLRP3 NLR family, pyrin domain containing 3
NOLC1 nucleolar and coiled-body phosphoprotein 1
NOTCH1 notch 1
NPHS1 nephrosis 1, congenital, Finnish type (nephrin)
NRD1 nardilysin (N-arginine dibasic convertase)
NUP107 nucleoporin 107kDa
NUP133 nucleoporin 133kDa
OPTN optineurin
PAF1 Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae)
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1
PARP1 poly (ADP-ribose) polymerase 1
PDCD6IP programmed cell death 6 interacting protein
PDE6D phosphodiesterase 6D, cGMP-specific, rod, delta
PDK1 pyruvate dehydrogenase kinase, isozyme 1
PEA15 phosphoprotein enriched in astrocytes 15
PHF21A PHD finger protein 21A
PIAS1 protein inhibitor of activated STAT, 1
PIM1 Pim-1 proto-oncogene, serine/threonine kinase
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1
PIP5K1C phosphatidylinositol-4-phosphate 5-kinase, type I, gamma
PIP5KL1 phosphatidylinositol-4-phosphate 5-kinase-like 1
PKD2 polycystic kidney disease 2 (autosomal dominant)
PKN1 protein kinase N1
PLCB2 phospholipase C, beta 2
PLK1 polo-like kinase 1
PML promyelocytic leukemia
PON1 paraoxonase 1
PPA1 pyrophosphatase (inorganic) 1
PPARG peroxisome proliferator-activated receptor gamma
PPL periplakin
PPP1R3A protein phosphatase 1, regulatory subunit 3A
PPP2R4 protein phosphatase 2A activator, regulatory subunit 4
PRG4 proteoglycan 4
PRKCA protein kinase C, alpha
PRKCB protein kinase C, beta
PRKCE protein kinase C, epsilon
PRPF40A PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae)
PSEN1 presenilin 1
PTEN phosphatase and tensin homolog
PTK2 protein tyrosine kinase 2
PTPN21 protein tyrosine phosphatase, non-receptor type 21
PXN paxillin
RAB11FIP1 RAB11 family interacting protein 1 (class I)
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
RALA v-ral simian leukemia viral oncogene homolog A (ras related)
RANBP9 RAN binding protein 9
RAPGEF3 Rap guanine nucleotide exchange factor (GEF) 3
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RGS14 regulator of G-protein signaling 14
RGS19 regulator of G-protein signaling 19
RNASE1 ribonuclease, RNase A family, 1 (pancreatic)
RNASE3 ribonuclease, RNase A family, 3
RNGTT RNA guanylyltransferase and 5'-phosphatase
RPF2 ribosome production factor 2 homolog (S. cerevisiae)
RPGR retinitis pigmentosa GTPase regulator
RPS3 ribosomal protein S3
RPTOR regulatory associated protein of MTOR, complex 1
RXFP1 relaxin/insulin-like family peptide receptor 1
SAFB scaffold attachment factor B
SAFB2 scaffold attachment factor B2
SAV1 salvador family WW domain containing protein 1
SCRIB scribbled planar cell polarity protein
SEC16A SEC16 homolog A (S. cerevisiae)
SEL1L sel-1 suppressor of lin-12-like (C. elegans)
SEPT2 septin 2
SH3GLB1 SH3-domain GRB2-like endophilin B1
SH3PXD2B SH3 and PX domains 2B
SHARPIN SHANK-associated RH domain interactor
SHC1 SHC (Src homology 2 domain containing) transforming protein 1
SHOC2 soc-2 suppressor of clear homolog (C. elegans)
SIRPA signal-regulatory protein alpha
SKP1 S-phase kinase-associated protein 1
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1
SLC9A3R2 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SNRPE small nuclear ribonucleoprotein polypeptide E
SP1 Sp1 transcription factor
SPG11 spastic paraplegia 11 (autosomal recessive)
SQSTM1 sequestosome 1
SRC SRC proto-oncogene, non-receptor tyrosine kinase
SRF serum response factor (c-fos serum response element-binding transcription factor)
SRPK1 SRSF protein kinase 1
STAT1 signal transducer and activator of transcription 1, 91kDa
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STK3 serine/threonine kinase 3
STRN striatin, calmodulin binding protein
STXBP4 syntaxin binding protein 4
SUZ12 SUZ12 polycomb repressive complex 2 subunit
SYK spleen tyrosine kinase
SYNE1 spectrin repeat containing, nuclear envelope 1
SYNE2 spectrin repeat containing, nuclear envelope 2
SYVN1 synovial apoptosis inhibitor 1, synoviolin
TANK TRAF family member-associated NFKB activator
TBK1 TANK-binding kinase 1
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box)
TERC telomerase RNA component
TGFB1I1 transforming growth factor beta 1 induced transcript 1
TGM2 transglutaminase 2
TICAM2 toll-like receptor adaptor molecule 2
TJP1 tight junction protein 1
TLR2 toll-like receptor 2
TLR4 toll-like receptor 4
TMEM173 transmembrane protein 173
TMEM198 transmembrane protein 198
TNF tumor necrosis factor
TNRC6A trinucleotide repeat containing 6A
TOP2A topoisomerase (DNA) II alpha 170kDa
TOP2B topoisomerase (DNA) II beta 180kDa
TP53 tumor protein p53
TP53BP1 tumor protein p53 binding protein 1
TP63 tumor protein p63
TP73 tumor protein p73
TPR translocated promoter region, nuclear basket protein
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
TRIM21 tripartite motif containing 21
TRIM5 tripartite motif containing 5
TRPC1 transient receptor potential cation channel, subfamily C, member 1
TRPC3 transient receptor potential cation channel, subfamily C, member 3
TRPC6 transient receptor potential cation channel, subfamily C, member 6
TTN titin
UNC80 unc-80 homolog (C. elegans)
UPF1 UPF1 regulator of nonsense transcripts homolog (yeast)
VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase
VPS29 vacuolar protein sorting 29 homolog (S. cerevisiae)
VPS35 vacuolar protein sorting 35 homolog (S. cerevisiae)
VRK1 vaccinia related kinase 1
WASF1 WAS protein family, member 1
WASF2 WAS protein family, member 2
WDR36 WD repeat domain 36
WDR83 WD repeat domain 83
WRAP53 WD repeat containing, antisense to TP53
XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1
YAP1 Yes-associated protein 1
YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma
ZFYVE16 zinc finger, FYVE domain containing 16
ZFYVE26 zinc finger, FYVE domain containing 26