scc Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
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Genes

175 genes co-occuring with the biological term scc in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ADAM17 ADAM metallopeptidase domain 17
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
AGER advanced glycosylation end product-specific receptor
AGR2 anterior gradient 2
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
ALK anaplastic lymphoma receptor tyrosine kinase
ANG angiogenin, ribonuclease, RNase A family, 5
APC adenomatous polyposis coli
AQP3 aquaporin 3 (Gill blood group)
AR androgen receptor
AREG amphiregulin
ATRAID all-trans retinoic acid-induced differentiation factor
AXIN1 axin 1
BAG1 BCL2-associated athanogene
BCL2L12 BCL2-like 12 (proline rich)
BECN1 beclin 1, autophagy related
BIRC5 baculoviral IAP repeat containing 5
BMP6 bone morphogenetic protein 6
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3
BSG basigin (Ok blood group)
BTC betacellulin
CCR7 chemokine (C-C motif) receptor 7
CD34 CD34 molecule
CD83 CD83 molecule
CDH13 cadherin 13
CDKN2A cyclin-dependent kinase inhibitor 2A
CDKN2B cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
CHEK2 checkpoint kinase 2
CHUK conserved helix-loop-helix ubiquitous kinase
CLDN1 claudin 1
COL17A1 collagen, type XVII, alpha 1
COPS5 COP9 signalosome subunit 5
CSMD1 CUB and Sushi multiple domains 1
CSTA cystatin A (stefin A)
CTLA4 cytotoxic T-lymphocyte-associated protein 4
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CTNNBIP1 catenin, beta interacting protein 1
CXCL12 chemokine (C-X-C motif) ligand 12
CXCR4 chemokine (C-X-C motif) receptor 4
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2
CYP2C8 cytochrome P450, family 2, subfamily C, polypeptide 8
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5
DDR2 discoidin domain receptor tyrosine kinase 2
DKK3 dickkopf WNT signaling pathway inhibitor 3
DMRT1 doublesex and mab-3 related transcription factor 1
DMRT3 doublesex and mab-3 related transcription factor 3
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
DOCK8 dedicator of cytokinesis 8
DPP4 dipeptidyl-peptidase 4
DSG2 desmoglein 2
DUSP1 dual specificity phosphatase 1
EGFR epidermal growth factor receptor
ENO2 enolase 2 (gamma, neuronal)
ERCC2 excision repair cross-complementation group 2
ERG v-ets avian erythroblastosis virus E26 oncogene homolog
ESR2 estrogen receptor 2 (ER beta)
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit
FADD Fas (TNFRSF6)-associated via death domain
FGFR1 fibroblast growth factor receptor 1
FGFR3 fibroblast growth factor receptor 3
FOS FBJ murine osteosarcoma viral oncogene homolog
FOXE1 forkhead box E1
FYN FYN proto-oncogene, Src family tyrosine kinase
GAL galanin/GMAP prepropeptide
GALNT3 polypeptide N-acetylgalactosaminyltransferase 3
GALR1 galanin receptor 1
GPR87 G protein-coupled receptor 87
GSTM1 glutathione S-transferase mu 1
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
HBEGF heparin-binding EGF-like growth factor
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HIPK2 homeodomain interacting protein kinase 2
HRAS Harvey rat sarcoma viral oncogene homolog
HSPA4 heat shock 70kDa protein 4
HSPB2 heat shock 27kDa protein 2
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
IL18 interleukin 18
IL1A interleukin 1, alpha
IL2 interleukin 2
IRF6 interferon regulatory factor 6
ITGA2B integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
ITGB6 integrin, beta 6
KLF4 Kruppel-like factor 4 (gut)
KRAS Kirsten rat sarcoma viral oncogene homolog
KRT10 keratin 10, type I
KRT18 keratin 18, type I
KRT19 keratin 19, type I
KRT7 keratin 7, type II
KRTAP5-2 keratin associated protein 5-2
LAMC2 laminin, gamma 2
LRP6 low density lipoprotein receptor-related protein 6
MAD1L1 MAD1 mitotic arrest deficient-like 1 (yeast)
MAPK1 mitogen-activated protein kinase 1
MAPK14 mitogen-activated protein kinase 14
MAPK3 mitogen-activated protein kinase 3
MARCKS myristoylated alanine-rich protein kinase C substrate
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MIR133A1 microRNA 133a-1
MIR133A2 microRNA 133a-2
MIR143 microRNA 143
MIR182 microRNA 182
MIR218-1 microRNA 218-1
MIR31 microRNA 31
MMP1 matrix metallopeptidase 1
MMP19 matrix metallopeptidase 19
MMP2 matrix metallopeptidase 2
MMP9 matrix metallopeptidase 9
MST1R macrophage stimulating 1 receptor
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MUC16 mucin 16, cell surface associated
MYC v-myc avian myelocytomatosis viral oncogene homolog
NCAM1 neural cell adhesion molecule 1
NKX2-1 NK2 homeobox 1
NOG noggin
NOS2 nitric oxide synthase 2, inducible
NOTCH1 notch 1
NRP1 neuropilin 1
OSMR oncostatin M receptor
PARP1 poly (ADP-ribose) polymerase 1
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor)
PDPN podoplanin
PERP PERP, TP53 apoptosis effector
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
PKM pyruvate kinase, muscle
PLAUR plasminogen activator, urokinase receptor
PLCG1 phospholipase C, gamma 1
POU5F1 POU class 5 homeobox 1
PPARG peroxisome proliferator-activated receptor gamma
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTK2 protein tyrosine kinase 2
RAP1GAP RAP1 GTPase activating protein
RARRES2 retinoic acid receptor responder (tazarotene induced) 2
RECK reversion-inducing-cysteine-rich protein with kazal motifs
REG1A regenerating islet-derived 1 alpha
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
SDC1 syndecan 1
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SIRT1 sirtuin 1
SMAD2 SMAD family member 2
SMAD4 SMAD family member 4
SMAD6 SMAD family member 6
SMAD7 SMAD family member 7
SNAI2 snail family zinc finger 2
SOST sclerostin
SOX2 SRY (sex determining region Y)-box 2
SPP1 secreted phosphoprotein 1
SRC SRC proto-oncogene, non-receptor tyrosine kinase
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
T T, brachyury homolog (mouse)
TAP2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
TAPBP TAP binding protein (tapasin)
TGFA transforming growth factor, alpha
TGFB1 transforming growth factor, beta 1
TGM2 transglutaminase 2
TIMELESS timeless circadian clock
TIMP1 TIMP metallopeptidase inhibitor 1
TIMP2 TIMP metallopeptidase inhibitor 2
TMPRSS2 transmembrane protease, serine 2
TMPRSS4 transmembrane protease, serine 4
TNC tenascin C
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TP53 tumor protein p53
TP63 tumor protein p63
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
VEGFA vascular endothelial growth factor A
VEGFC vascular endothelial growth factor C
VOPP1 vesicular, overexpressed in cancer, prosurvival protein 1