schistosomiasis Gene Set

Dataset DISEASES Text-mining Gene-Disease Association Evidence Scores
Category disease or phenotype associations
Type disease
Description A parasitic helminthiasis infectious disease that involves infection of the intestine, urinary tract, skin, liver and spleen caused by multiple species of the trematode fluke of the genus Schistosoma. The symptoms include fever, chills, nausea, abdominal pain, diarrhea, malaise, myalgia, liver and spleen enlargement, rash and hematuria. (Human Disease Ontology, DOID_1395)
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Genes

309 genes co-occuring with the disease schistosomiasis in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
EPGN epithelial mitogen 2.35924
CHRM2 cholinergic receptor, muscarinic 2 1.93796
SRCIN1 SRC kinase signaling inhibitor 1 1.5507
CD4 CD4 molecule 1.54805
GSTA3 glutathione S-transferase alpha 3 1.4733
GSTA2 glutathione S-transferase alpha 2 1.47154
GSTA4 glutathione S-transferase alpha 4 1.47023
GSTA1 glutathione S-transferase alpha 1 1.46363
CD79A CD79a molecule, immunoglobulin-associated alpha 1.36335
TSPAN2 tetraspanin 2 1.32017
FBRS fibrosin 1.2521
IL4 interleukin 4 1.24385
GOT2 glutamic-oxaloacetic transaminase 2, mitochondrial 1.10258
TXN thioredoxin 1.08747
ALB albumin 1.06732
BUD31 BUD31 homolog (S. cerevisiae) 1.06606
TPI1 triosephosphate isomerase 1 1.0627
CDC42SE1 CDC42 small effector 1 1.0244
ALPPL2 alkaline phosphatase, placental-like 2 1.01301
ALPP alkaline phosphatase, placental 1.01216
ALPL alkaline phosphatase, liver/bone/kidney 1.01174
NELFCD negative elongation factor complex member C/D 0.988957
GSR glutathione reductase 0.9839
TGFB1 transforming growth factor, beta 1 0.978848
IL13 interleukin 13 0.978848
LGMN legumain 0.956196
MRGPRF MAS-related GPR, member F 0.955779
TAGLN transgelin 0.954525
RNASE3 ribonuclease, RNase A family, 3 0.942858
IL10 interleukin 10 0.922149
IL2 interleukin 2 0.912668
ARG1 arginase 1 0.879014
TAC1 tachykinin, precursor 1 0.874509
EPX eosinophil peroxidase 0.86714
F2 coagulation factor II (thrombin) 0.851992
PRDX5 peroxiredoxin 5 0.851583
CTSB cathepsin B 0.837656
GAPDH glyceraldehyde-3-phosphate dehydrogenase 0.836017
TNF tumor necrosis factor 0.814283
MRGPRE MAS-related GPR, member E 0.803616
TXNDC9 thioredoxin domain containing 9 0.801974
GOT1 glutamic-oxaloacetic transaminase 1, soluble 0.794181
POLI polymerase (DNA directed) iota 0.789672
RETNLB resistin like beta 0.789262
GLRX glutaredoxin (thioltransferase) 0.788852
PMM1 phosphomannomutase 1 0.762678
CCL3 chemokine (C-C motif) ligand 3 0.757786
IFNGR1 interferon gamma receptor 1 0.751271
GGT1 gamma-glutamyltransferase 1 0.746391
TIMP1 TIMP metallopeptidase inhibitor 1 0.738676
TACR1 tachykinin receptor 1 0.736243
FOXP3 forkhead box P3 0.734217
IL23A interleukin 23, alpha subunit p19 0.685891
IL5 interleukin 5 0.683093
MRC1 mannose receptor, C type 1 0.6791
CCL24 chemokine (C-C motif) ligand 24 0.672324
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced 0.670333
CYB5A cytochrome b5 type A (microsomal) 0.667152
BCHE butyrylcholinesterase 0.666358
AADACL3 arylacetamide deacetylase-like 3 0.663578
CDYL chromodomain protein, Y-like 0.662387
SST somatostatin 0.654463
TSPAN1 tetraspanin 1 0.653276
SERPINB8 serpin peptidase inhibitor, clade B (ovalbumin), member 8 0.650508
FCN2 ficolin (collagen/fibrinogen domain containing lectin) 2 0.644586
PRAMEF12 PRAME family member 12 0.641433
CTSL cathepsin L 0.636708
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) 0.62885
HPGDS hematopoietic prostaglandin D synthase 0.62885
HSPA4 heat shock 70kDa protein 4 0.6214
IFNG interferon, gamma 0.6003
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2 0.596402
HDAC8 histone deacetylase 8 0.592895
THY1 Thy-1 cell surface antigen 0.581996
VIPR2 vasoactive intestinal peptide receptor 2 0.580439
LAP3 leucine aminopeptidase 3 0.579272
HSPG2 heparan sulfate proteoglycan 2 0.566831
IL4I1 interleukin 4 induced 1 0.561781
PRDX2 peroxiredoxin 2 0.561004
OR13F1 olfactory receptor, family 13, subfamily F, member 1 0.554015
SOD2 superoxide dismutase 2, mitochondrial 0.538893
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene) 0.534248
FN1 fibronectin 1 0.532701
TPM3 tropomyosin 3 0.531928
MSRB2 methionine sulfoxide reductase B2 0.528835
CD69 CD69 molecule 0.528835
IL17A interleukin 17A 0.526518
SSTR3 somatostatin receptor 3 0.526518
G6PC glucose-6-phosphatase, catalytic subunit 0.521502
VIP vasoactive intestinal peptide 0.51842
CD28 CD28 molecule 0.503058
TCHH trichohyalin 0.501527
NBPF10 neuroblastoma breakpoint family, member 10 0.494648
ICAM1 intercellular adhesion molecule 1 0.490072
NPS neuropeptide S 0.482844
ARAP2 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 0.478289
MRGPRD MAS-related GPR, member D 0.474119
IL4R interleukin 4 receptor 0.467306
GIPC3 GIPC PDZ domain containing family, member 3 0.457109
SHE Src homology 2 domain containing E 0.453716
TLR2 toll-like receptor 2 0.448441
CD86 CD86 molecule 0.443171
TSPO translocator protein (18kDa) 0.44129
IL1B interleukin 1, beta 0.439034
HYAL1 hyaluronoglucosaminidase 1 0.436402
FUT5 fucosyltransferase 5 (alpha (1,3) fucosyltransferase) 0.436026
MAPKAP1 mitogen-activated protein kinase associated protein 1 0.433397
MDH1 malate dehydrogenase 1, NAD (soluble) 0.432646
MSRB1 methionine sulfoxide reductase B1 0.431144
MAP1S microtubule-associated protein 1S 0.429266
CAMK2D calcium/calmodulin-dependent protein kinase II delta 0.424765
WLS wntless Wnt ligand secretion mediator 0.421016
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) 0.415773
MRPS7 mitochondrial ribosomal protein S7 0.406798
PPIG peptidylprolyl isomerase G (cyclophilin G) 0.405305
ACSM2A acyl-CoA synthetase medium-chain family member 2A 0.401945
PIWIL1 piwi-like RNA-mediated gene silencing 1 0.400453
GSTM2 glutathione S-transferase mu 2 (muscle) 0.399707
CCL2 chemokine (C-C motif) ligand 2 0.399334
CCL5 chemokine (C-C motif) ligand 5 0.392629
LYZ lysozyme 0.390769
SPAM1 sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding) 0.390025
IFT57 intraflagellar transport 57 0.388909
CYP2B6 cytochrome P450, family 2, subfamily B, polypeptide 6 0.384451
CTLA4 cytotoxic T-lymphocyte-associated protein 4 0.384079
PYDC1 PYD (pyrin domain) containing 1 0.383337
LOX lysyl oxidase 0.382594
C3 complement component 3 0.377402
GGT2 gamma-glutamyltransferase 2 0.373698
PTPN9 protein tyrosine phosphatase, non-receptor type 9 0.371107
PRDX1 peroxiredoxin 1 0.369258
CAT catalase 0.36704
HPCA hippocalcin 0.364824
CD1D CD1d molecule 0.363347
ZFYVE1 zinc finger, FYVE domain containing 1 0.344574
CTSS cathepsin S 0.343106
TNFRSF18 tumor necrosis factor receptor superfamily, member 18 0.343106
GUSB glucuronidase, beta 0.342739
AIF1 allograft inflammatory factor 1 0.340539
CD8A CD8a molecule 0.338707
FCGR1B Fc fragment of IgG, high affinity Ib, receptor (CD64) 0.338707
CCL11 chemokine (C-C motif) ligand 11 0.336876
NFIL3 nuclear factor, interleukin 3 regulated 0.335412
PSMA5 proteasome (prosome, macropain) subunit, alpha type, 5 0.333949
MMP2 matrix metallopeptidase 2 0.330295
GGPS1 geranylgeranyl diphosphate synthase 1 0.328834
ACPP acid phosphatase, prostate 0.320454
SNHG12 small nucleolar RNA host gene 12 0.32009
PFKM phosphofructokinase, muscle 0.318272
PPIA peptidylprolyl isomerase A (cyclophilin A) 0.316456
RPL7 ribosomal protein L7 0.315366
GPX5 glutathione peroxidase 5 0.307757
AFP alpha-fetoprotein 0.307395
COL1A2 collagen, type I, alpha 2 0.304864
GPX4 glutathione peroxidase 4 0.304503
ASGR2 asialoglycoprotein receptor 2 0.303059
CD276 CD276 molecule 0.301976
PYCR1 pyrroline-5-carboxylate reductase 1 0.301615
MMP9 matrix metallopeptidase 9 0.300173
VIPR1 vasoactive intestinal peptide receptor 1 0.297651
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) 0.297291
PRIM1 primase, DNA, polypeptide 1 (49kDa) 0.293334
SCRIB scribbled planar cell polarity protein 0.293334
EML1 echinoderm microtubule associated protein like 1 0.291898
HPRT1 hypoxanthine phosphoribosyltransferase 1 0.29118
FKBP9 FK506 binding protein 9, 63 kDa 0.290462
GPX1 glutathione peroxidase 1 0.290103
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 0.288668
FKBP7 FK506 binding protein 7 0.28831
ASGR1 asialoglycoprotein receptor 1 0.287593
SSTR2 somatostatin receptor 2 0.284371
MID2 midline 2 0.284013
STOML2 stomatin (EPB72)-like 2 0.28294
CD209 CD209 molecule 0.280796
RNASE2 ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin) 0.280082
CXCL2 chemokine (C-X-C motif) ligand 2 0.27794
FKBP3 FK506 binding protein 3, 25kDa 0.277584
RGPD3 RANBP2-like and GRIP domain containing 3 0.268687
IGHV3-30 immunoglobulin heavy variable 3-30 0.267977
ARSB arylsulfatase B 0.267267
TES testin LIM domain protein 0.266913
CXCL14 chemokine (C-X-C motif) ligand 14 0.26514
FKBP6 FK506 binding protein 6, 36kDa 0.263722
FTL ferritin, light polypeptide 0.256299
FTH1 ferritin, heavy polypeptide 1 0.256299
DLGAP5 discs, large (Drosophila) homolog-associated protein 5 0.255946
ACHE acetylcholinesterase (Yt blood group) 0.25207
CTGF connective tissue growth factor 0.251718
DSTN destrin (actin depolymerizing factor) 0.249608
TACSTD2 tumor-associated calcium signal transducer 2 0.248554
PA2G4 proliferation-associated 2G4, 38kDa 0.248203
ACE angiotensin I converting enzyme 0.243295
TFRC transferrin receptor 0.243295
MEGF6 multiple EGF-like-domains 6 0.241895
TPM1 tropomyosin 1 (alpha) 0.241546
SERPINC1 serpin peptidase inhibitor, clade C (antithrombin), member 1 0.241196
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1 0.240847
SLC5A8 solute carrier family 5 (sodium/monocarboxylate cotransporter), member 8 0.240148
NDUFAB1 NADH dehydrogenase (ubiquinone) 1, alpha/beta subcomplex, 1, 8kDa 0.238752
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 0.238403
CTSV cathepsin V 0.23666
PRODH proline dehydrogenase (oxidase) 1 0.23666
HDAC9 histone deacetylase 9 0.235964
HK1 hexokinase 1 0.23353
TP53 tumor protein p53 0.231448
SSTR1 somatostatin receptor 1 0.230409
CTSD cathepsin D 0.229716
CD8B CD8b molecule 0.228333
CD80 CD80 molecule 0.227988
IDH3G isocitrate dehydrogenase 3 (NAD+) gamma 0.227297
HMGB3 high mobility group box 3 0.227297
DNAJC16 DnaJ (Hsp40) homolog, subfamily C, member 16 0.222479
CPS1 carbamoyl-phosphate synthase 1, mitochondrial 0.21974
IDH3A isocitrate dehydrogenase 3 (NAD+) alpha 0.219398
EPS8 epidermal growth factor receptor pathway substrate 8 0.216672
TIMP4 TIMP metallopeptidase inhibitor 4 0.215653
CSN1S1 casein alpha s1 0.214975
WASH7P WAS protein family homolog 7 pseudogene 0.211597
WASH1 WAS protein family homolog 1 0.208245
PEPD peptidase D 0.207245
GALP galanin-like peptide 0.207245
WASH6P WAS protein family homolog 6 pseudogene 0.205916
LGALS3 lectin, galactoside-binding, soluble, 3 0.201635
IDH3B isocitrate dehydrogenase 3 (NAD+) beta 0.201308
CXCR3 chemokine (C-X-C motif) receptor 3 0.198064
PNP purine nucleoside phosphorylase 0.197742
UCKL1 uridine-cytidine kinase 1-like 1 0.196459
HSPA9 heat shock 70kDa protein 9 (mortalin) 0.195501
GPI glucose-6-phosphate isomerase 0.195183
SMAD2 SMAD family member 2 0.192971
FABP9 fatty acid binding protein 9, testis 0.191719
TTR transthyretin 0.191097
UCK1 uridine-cytidine kinase 1 0.190476
MIR223 microRNA 223 0.187719
SERPINF2 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2 0.187415
DTYMK deoxythymidylate kinase (thymidylate kinase) 0.187113
LIM2 lens intrinsic membrane protein 2, 19kDa 0.184128
FKBP2 FK506 binding protein 2, 13kDa 0.180367
TNFSF18 tumor necrosis factor (ligand) superfamily, member 18 0.172544
KLRG1 killer cell lectin-like receptor subfamily G, member 1 0.171535
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) 0.171535
MFF mitochondrial fission factor 0.171036
CP ceruloplasmin (ferroxidase) 0.168381
LCAT lecithin-cholesterol acyltransferase 0.167452
TRO trophinin 0.167224
ALDOC aldolase C, fructose-bisphosphate 0.166544
CANX calnexin 0.164359
TUBGCP4 tubulin, gamma complex associated protein 4 0.164149
DUOXA1 dual oxidase maturation factor 1 0.164149
CD40 CD40 molecule, TNF receptor superfamily member 5 0.164149
HP haptoglobin 0.162306
PRSS21 protease, serine, 21 (testisin) 0.161523
SULT1A4 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 4 0.161139
ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1 0.15948
HPR haptoglobin-related protein 0.159302
RAN RAN, member RAS oncogene family 0.159302
CD40LG CD40 ligand 0.158778
UCK2 uridine-cytidine kinase 2 0.157765
MT-ATP8 ATP synthase F0 subunit 8 0.14535
NGF nerve growth factor (beta polypeptide) 0.144114
WAPAL wings apart-like homolog (Drosophila) 0.143116
NPY1R neuropeptide Y receptor Y1 0.142268
BATF2 basic leucine zipper transcription factor, ATF-like 2 0.142258
CTCFL CCCTC-binding factor (zinc finger protein)-like 0.141553
FPR1 formyl peptide receptor 1 0.139129
IL22RA1 interleukin 22 receptor, alpha 1 0.138394
IGLV2-14 immunoglobulin lambda variable 2-14 0.137988
KPNA2 karyopherin alpha 2 (RAG cohort 1, importin alpha 1) 0.137599
WISP3 WNT1 inducible signaling pathway protein 3 0.13713
SSTR4 somatostatin receptor 4 0.136601
HLA-DPB1 major histocompatibility complex, class II, DP beta 1 0.135301
NDUFS4 NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase) 0.134691
CRYBB2 crystallin, beta B2 0.134538
ARPP21 cAMP-regulated phosphoprotein, 21kDa 0.134103
LGALS9 lectin, galactoside-binding, soluble, 9 0.134008
DLL1 delta-like 1 (Drosophila) 0.133911
OGG1 8-oxoguanine DNA glycosylase 0.133645
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1 0.133385
ROM1 retinal outer segment membrane protein 1 0.133148
HLA-G major histocompatibility complex, class I, G 0.132687
MCF2 MCF.2 cell line derived transforming sequence 0.132154
CRYGD crystallin, gamma D 0.131747
TLR6 toll-like receptor 6 0.130844
PRDX6 peroxiredoxin 6 0.130044
IL33 interleukin 33 0.129839
IRF6 interferon regulatory factor 6 0.129632
HSD17B6 hydroxysteroid (17-beta) dehydrogenase 6 0.128783
SOCS3 suppressor of cytokine signaling 3 0.128511
CDIPT CDP-diacylglycerol--inositol 3-phosphatidyltransferase 0.128254
IL22 interleukin 22 0.127204
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 0.126997
TLR4 toll-like receptor 4 0.126842
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39) 0.12679
PTER phosphotriesterase related 0.126283
GLS2 glutaminase 2 (liver, mitochondrial) 0.126062
FLNA filamin A, alpha 0.124432
MS4A2 membrane-spanning 4-domains, subfamily A, member 2 0.12428
CXCR4 chemokine (C-X-C motif) receptor 4 0.123549
CYLD cylindromatosis (turban tumor syndrome) 0.123223
CCL19 chemokine (C-C motif) ligand 19 0.122889
TLR1 toll-like receptor 1 0.121743
TLR3 toll-like receptor 3 0.121743
TFR2 transferrin receptor 2 0.121455
TF transferrin 0.120024
PCNA proliferating cell nuclear antigen 0.119945
LPO lactoperoxidase 0.119508
PI3 peptidase inhibitor 3, skin-derived 0.118857
HAMP hepcidin antimicrobial peptide 0.118103
TLR9 toll-like receptor 9 0.118018