schizophrenia Gene Set

Dataset DISEASES Experimental Gene-Disease Association Evidence Scores
Category disease or phenotype associations
Type disease
Description A major psychotic disorder characterized by abnormalities in the perception or expression of reality. It affects the cognitive and psychomotor functions. Common clinical signs and symptoms include delusions, hallucinations, disorganized thinking, and retreat from reality.|A severe emotional disorder of psychotic depth characteristically marked by a retreat from reality with delusion formation, HALLUCINATIONS, emotional disharmony, and regressive behavior. (Experimental Factor Ontology, EFO_0000692)
Similar Terms
Downloads & Tools

Genes

131 genes associated with the disease schizophrenia in GWAS datasets from the DISEASES Experimental Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
TRIM26 tripartite motif containing 26 1.17894
POM121L2 POM121 transmembrane nucleoporin-like 2 0.894262
NKAPL NFKB activating protein-like 0.830123
TSPAN18 tetraspanin 18 0.817078
DPYD dihydropyrimidine dehydrogenase 0.790827
LSM1 LSM1, U6 small nuclear RNA associated 0.724323
NOTCH4 notch 4 0.69843
NRGN neurogranin (protein kinase C substrate, RC3) 0.602429
HHAT hedgehog acyltransferase 0.552621
HIST1H2AH histone cluster 1, H2ah 0.52461
MPC2 mitochondrial pyruvate carrier 2 0.52461
CNNM2 cyclin and CBS domain divalent metal cation transport mediator 2 0.486425
NT5C2 5'-nucleotidase, cytosolic II 0.464771
AMPD3 adenosine monophosphate deaminase 3 0.449873
SLC39A10 solute carrier family 39 (zinc transporter), member 10 0.438544
SDCCAG8 serologically defined colon cancer antigen 8 0.438544
MUSTN1 musculoskeletal, embryonic nuclear protein 1 0.429338
ITIH4 inter-alpha-trypsin inhibitor heavy chain family, member 4 0.429338
EHF ets homologous factor 0.4215
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 0.4215
CCDC39 coiled-coil domain containing 39 0.403461
PIK3C2A phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha 0.403461
SLC26A9 solute carrier family 26 (anion exchanger), member 9 0.403461
CEACAM21 carcinoembryonic antigen-related cell adhesion molecule 21 0.403461
ZNF804A zinc finger protein 804A 0.368757
SLAMF1 signaling lymphocytic activation molecule family member 1 0.368757
BRD1 bromodomain containing 1 0.368757
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 0.368757
TRANK1 tetratricopeptide repeat and ankyrin repeat containing 1 0.368757
MMP16 matrix metallopeptidase 16 (membrane-inserted) 0.368757
VRK2 vaccinia related kinase 2 0.345945
AS3MT arsenite methyltransferase 0.345945
GRIK3 glutamate receptor, ionotropic, kainate 3 0.345945
PKNOX2 PBX/knotted 1 homeobox 2 0.327313
RPP21 ribonuclease P/MRP 21kDa subunit 0.327313
ANKS1B ankyrin repeat and sterile alpha motif domain containing 1B 0.327313
GPR137B G protein-coupled receptor 137B 0.311576
RELN reelin 0.311576
PRMT6 protein arginine methyltransferase 6 0.311576
DRD2 dopamine receptor D2 0.311576
HUNK hormonally up-regulated Neu-associated kinase 0.311576
CHST8 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8 0.297866
PTBP2 polypyrimidine tract binding protein 2 0.297866
IL1A interleukin 1, alpha 0.285417
CTNNA3 catenin (cadherin-associated protein), alpha 3 0.285417
ADGRL3 adhesion G protein-coupled receptor L3 0.274608
SNX29 sorting nexin 29 0.264872
PRKCZ protein kinase C, zeta 0.256228
RBM19 RNA binding motif protein 19 0.256228
ADAMTS6 ADAM metallopeptidase with thrombospondin type 1 motif, 6 0.256228
CCDC60 coiled-coil domain containing 60 0.256228
MAP3K9 mitogen-activated protein kinase kinase kinase 9 0.256228
SLCO6A1 solute carrier organic anion transporter family, member 6A1 0.256228
TCF4 transcription factor 4 0.256228
ZFP90 ZFP90 zinc finger protein 0.256228
STT3A STT3A, subunit of the oligosaccharyltransferase complex (catalytic) 0.256228
WWOX WW domain containing oxidoreductase 0.256228
LYZL4 lysozyme-like 4 0.256228
PLAA phospholipase A2-activating protein 0.197766
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) 0.197766
FXR1 fragile X mental retardation, autosomal homolog 1 0.197766
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 0.197766
ZNF706 zinc finger protein 706 0.197766
CLC Charcot-Leyden crystal galectin 0.197766
PTPRG protein tyrosine phosphatase, receptor type, G 0.197766
CLDN1 claudin 1 0.197766
PTPN21 protein tyrosine phosphatase, non-receptor type 21 0.197766
CALN1 calneuron 1 0.197766
AGBL1 ATP/GTP binding protein-like 1 0.197766
MTAP methylthioadenosine phosphorylase 0.197766
CACNA1C calcium channel, voltage-dependent, L type, alpha 1C subunit 0.197766
MYO18B myosin XVIIIB 0.197766
GRID1 glutamate receptor, ionotropic, delta 1 0.197766
PLCB2 phospholipase C, beta 2 0.15771
ITSN2 intersectin 2 0.15771
PID1 phosphotyrosine interaction domain containing 1 0.15771
FEZ1 fasciculation and elongation protein zeta 1 (zygin I) 0.15771
CXCL12 chemokine (C-X-C motif) ligand 12 0.15771
RERE arginine-glutamic acid dipeptide (RE) repeats 0.15771
PCDH20 protocadherin 20 0.15771
RSL24D1 ribosomal L24 domain containing 1 0.15771
IFT88 intraflagellar transport 88 0.15771
CDKN3 cyclin-dependent kinase inhibitor 3 0.15771
METTL15 methyltransferase like 15 0.15771
BMP7 bone morphogenetic protein 7 0.15771
ANXA1 annexin A1 0.15771
SNX19 sorting nexin 19 0.15771
ACSM1 acyl-CoA synthetase medium-chain family member 1 0.15771
PPFIA2 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2 0.126165
GPC1 glypican 1 0.126165
RORA RAR-related orphan receptor A 0.126165
ATXN1 ataxin 1 0.126165
PRRC2A proline-rich coiled-coil 2A 0.126165
MAD1L1 MAD1 mitotic arrest deficient-like 1 (yeast) 0.126165
CDC42 cell division cycle 42 0.126165
ROBO2 roundabout, axon guidance receptor, homolog 2 (Drosophila) 0.126165
NPAS3 neuronal PAS domain protein 3 0.126165
NEDD1 neural precursor cell expressed, developmentally down-regulated 1 0.126165
DRAXIN dorsal inhibitory axon guidance protein 0.126165
MSRA methionine sulfoxide reductase A 0.126165
MAST4 microtubule associated serine/threonine kinase family member 4 0.100789
MXRA5 matrix-remodelling associated 5 0.100789
ARL4P ADP-ribosylation factor-like 4 pseudogene 0.100789
TRAF3 TNF receptor-associated factor 3 0.100789
ARNTL aryl hydrocarbon receptor nuclear translocator-like 0.100789
LNX2 ligand of numb-protein X 2 0.100789
HLA-DRB1 major histocompatibility complex, class II, DR beta 1 0.100789
ARHGAP31 Rho GTPase activating protein 31 0.100789
FBXO11 F-box protein 11 0.080593
TNIK TRAF2 and NCK interacting kinase 0.080593
MFAP3 microfibrillar-associated protein 3 0.080593
CNTNAP5 contactin associated protein-like 5 0.080593
SHISA9 shisa family member 9 0.080593
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 0.080593
KIF26B kinesin family member 26B 0.064973
SH3RF1 SH3 domain containing ring finger 1 0.064973
TMTC1 transmembrane and tetratricopeptide repeat containing 1 0.064973
SUCNR1 succinate receptor 1 0.064973
FMR1NB fragile X mental retardation 1 neighbor 0.064973
HABP2 hyaluronan binding protein 2 0.064973
CIART circadian associated repressor of transcription 0.064973
CACNA1I calcium channel, voltage-dependent, T type, alpha 1I subunit 0.052255
SETBP1 SET binding protein 1 0.052255
ARAP1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 0.052255
NLRC5 NLR family, CARD domain containing 5 0.052255
ANK3 ankyrin 3, node of Ranvier (ankyrin G) 0.052255
YLPM1 YLP motif containing 1 0.052255
ZFYVE28 zinc finger, FYVE domain containing 28 0.043246
MMS22L MMS22-like, DNA repair protein 0.043246
ZBED9 zinc finger, BED-type containing 9 0.043246
EBF2 early B-cell factor 2 0.035343