sclerosing cholangitis Gene Set

Dataset DISEASES Text-mining Gene-Disease Association Evidence Scores
Category disease or phenotype associations
Type disease
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Genes

151 genes co-occuring with the disease sclerosing cholangitis in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
ALPPL2 alkaline phosphatase, placental-like 2 1.9066
ALPP alkaline phosphatase, placental 1.90614
ALPL alkaline phosphatase, liver/bone/kidney 1.90521
ABCB4 ATP-binding cassette, sub-family B (MDR/TAP), member 4 1.63455
SEPSECS Sep (O-phosphoserine) tRNA:Sec (selenocysteine) tRNA synthase 1.38909
NISCH nischarin 1.34984
GGT1 gamma-glutamyltransferase 1 1.33414
GOT1 glutamic-oxaloacetic transaminase 1, soluble 1.27955
GOT2 glutamic-oxaloacetic transaminase 2, mitochondrial 1.24602
GPBAR1 G protein-coupled bile acid receptor 1 1.22042
HLA-C major histocompatibility complex, class I, C 1.17378
LTF lactotransferrin 1.07698
SP100 SP100 nuclear antigen 1.0265
MADCAM1 mucosal vascular addressin cell adhesion molecule 1 1.01259
CCL25 chemokine (C-C motif) ligand 25 0.975482
PRTN3 proteinase 3 0.933727
NR1H4 nuclear receptor subfamily 1, group H, member 4 0.876148
CTSG cathepsin G 0.873281
GGT2 gamma-glutamyltransferase 2 0.865912
CD79A CD79a molecule, immunoglobulin-associated alpha 0.853221
HES1 hes family bHLH transcription factor 1 0.840525
CD40LG CD40 ligand 0.818796
BPI bactericidal/permeability-increasing protein 0.801564
RIMBP2 RIMS binding protein 2 0.798692
MICA MHC class I polypeptide-related sequence A 0.796232
ALB albumin 0.786803
TNFRSF21 tumor necrosis factor receptor superfamily, member 21 0.757786
KRT19 keratin 19, type I 0.743141
CD4 CD4 molecule 0.742735
CLDN1 claudin 1 0.724907
DAGLB diacylglycerol lipase, beta 0.724098
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) 0.721673
MPO myeloperoxidase 0.720461
MST1 macrophage stimulating 1 0.712392
ENAM enamelin 0.699517
HLA-DRB1 major histocompatibility complex, class II, DR beta 1 0.697911
TNF tumor necrosis factor 0.674713
KRT7 keratin 7, type II 0.653276
F2 coagulation factor II (thrombin) 0.640645
SLC10A1 solute carrier family 10 (sodium/bile acid cotransporter), member 1 0.622183
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4 0.614356
NR1I2 nuclear receptor subfamily 1, group I, member 2 0.613574
PDZD2 PDZ domain containing 2 0.604201
ABCB11 ATP-binding cassette, sub-family B (MDR/TAP), member 11 0.595233
ASGR2 asialoglycoprotein receptor 2 0.593674
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1 0.583163
HLA-A major histocompatibility complex, class I, A 0.578494
ASGR1 asialoglycoprotein receptor 1 0.576939
DMBT1 deleted in malignant brain tumors 1 0.544318
CIRH1A cirrhosis, autosomal recessive 1A (cirhin) 0.538118
SLCO1C1 solute carrier organic anion transporter family, member 1C1 0.536183
FUT2 fucosyltransferase 2 (secretor status included) 0.516494
KHDRBS3 KH domain containing, RNA binding, signal transduction associated 3 0.491215
DLG5 discs, large homolog 5 (Drosophila) 0.489311
ARL6IP5 ADP-ribosylation factor-like 6 interacting protein 5 0.47753
ENO1 enolase 1, (alpha) 0.45447
NOD2 nucleotide-binding oligomerization domain containing 2 0.449571
HLA-DRB3 major histocompatibility complex, class II, DR beta 3 0.446558
IL10 interleukin 10 0.44129
HLA-E major histocompatibility complex, class I, E 0.436778
BAAT bile acid CoA:amino acid N-acyltransferase 0.436026
PNPLA3 patatin-like phospholipase domain containing 3 0.436026
KRAS Kirsten rat sarcoma viral oncogene homolog 0.435275
TJP2 tight junction protein 2 0.431519
ICAM1 intercellular adhesion molecule 1 0.42214
GPC6 glypican 6 0.415024
HLA-DRB4 major histocompatibility complex, class II, DR beta 4 0.413153
CIC capicua transcriptional repressor 0.411283
GPR35 G protein-coupled receptor 35 0.409787
ABO ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase) 0.401945
CARD10 caspase recruitment domain family, member 10 0.398962
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog 0.397471
SLC22A4 solute carrier family 22 (organic cation/zwitterion transporter), member 4 0.388166
IL6 interleukin 6 0.387794
TP53 tumor protein p53 0.387051
SLC22A5 solute carrier family 22 (organic cation/carnitine transporter), member 5 0.383708
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene) 0.379626
MICB MHC class I polypeptide-related sequence B 0.376661
SP140 SP140 nuclear body protein 0.373328
OPTN optineurin 0.36741
DPF2 D4, zinc and double PHD fingers family 2 0.362609
NOX3 NADPH oxidase 3 0.359289
CTDSP2 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2 0.340539
ADAD1 adenosine deaminase domain containing 1 (testis-specific) 0.337242
CDKN2A cyclin-dependent kinase inhibitor 2A 0.331756
CA2 carbonic anhydrase II 0.329565
MMP3 matrix metallopeptidase 3 0.3292
SLC4A2 solute carrier family 4 (anion exchanger), member 2 0.3292
FOXP3 forkhead box P3 0.317909
NCAM1 neural cell adhesion molecule 1 0.317545
STPG1 sperm-tail PG-rich repeat containing 1 0.317182
TCF4 transcription factor 4 0.313552
HLA-B major histocompatibility complex, class I, B 0.301254
HLA-DRB5 major histocompatibility complex, class II, DR beta 5 0.299812
HRAS Harvey rat sarcoma viral oncogene homolog 0.298731
NUDT1 nudix (nucleoside diphosphate linked moiety X)-type motif 1 0.298011
RDX radixin 0.297651
ZMIZ1 zinc finger, MIZ-type containing 1 0.297651
SNRNP40 small nuclear ribonucleoprotein 40kDa (U5) 0.289386
RELT RELT tumor necrosis factor receptor 0.289027
NOTCH1 notch 1 0.279724
VPS33B vacuolar protein sorting 33 homolog B (yeast) 0.275801
CD86 CD86 molecule 0.275445
CLDN7 claudin 7 0.274732
JAG1 jagged 1 0.273308
ATG16L1 autophagy related 16-like 1 (S. cerevisiae) 0.270108
KIAA1109 KIAA1109 0.266558
NKX2-3 NK2 homeobox 3 0.26514
NTHL1 nth endonuclease III-like 1 (E. coli) 0.264785
EYA4 EYA transcriptional coactivator and phosphatase 4 0.264431
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1 0.25877
SULT2A1 sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1 0.257358
PSMA2 proteasome (prosome, macropain) subunit, alpha type, 2 0.254888
NEIL1 nei endonuclease VIII-like 1 (E. coli) 0.250663
TNFAIP6 tumor necrosis factor, alpha-induced protein 6 0.248554
MMEL1 membrane metallo-endopeptidase-like 1 0.247852
SLC51A solute carrier family 51, alpha subunit 0.241546
MCOLN1 mucolipin 1 0.239799
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2 0.237357
PTPRE protein tyrosine phosphatase, receptor type, E 0.233878
MTX1 metaxin 1 0.233878
OGDH oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) 0.228333
GNPTAB N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits 0.226952
TFF3 trefoil factor 3 (intestinal) 0.226607
NDUFS3 NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase) 0.224196
SLCO1B1 solute carrier organic anion transporter family, member 1B1 0.222479
IL1B interleukin 1, beta 0.221108
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid) 0.211934
ARHGEF7 Rho guanine nucleotide exchange factor (GEF) 7 0.208579
ARG1 arginase 1 0.203604
PIDD1 p53-induced death domain protein 1 0.20229
PDZK1 PDZ domain containing 1 0.200331
SPG20 spastic paraplegia 20 (Troyer syndrome) 0.198386
IL2RA interleukin 2 receptor, alpha 0.195501
CTGF connective tissue growth factor 0.195183
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 0.188326
DLAT dihydrolipoamide S-acetyltransferase 0.18591
SLCO2B1 solute carrier organic anion transporter family, member 2B1 0.177851
NEU2 sialidase 2 (cytosolic sialidase) 0.172799
ACTA1 actin, alpha 1, skeletal muscle 0.172038
SLCO4A1 solute carrier organic anion transporter family, member 4A1 0.171036
RPL5 ribosomal protein L5 0.170789
TJP1 tight junction protein 1 0.168148
PER3 period circadian clock 3 0.166544
MUC4 mucin 4, cell surface associated 0.165217
WNT2B wingless-type MMTV integration site family, member 2B 0.162707
LTBP3 latent transforming growth factor beta binding protein 3 0.162306
CP ceruloplasmin (ferroxidase) 0.160387
IL2 interleukin 2 0.158951
AIRE autoimmune regulator 0.158266
GLRX glutaredoxin (thioltransferase) 0.157602