scoliosis Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description An appreciable lateral deviation in the normally straight vertical line of the spine. (Dorland, 27th ed) (Experimental Factor Ontology, EFO_0004273)
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Genes

59 genes co-occuring with the biological term scoliosis in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
AANAT aralkylamine N-acetyltransferase
ACAN aggrecan
ACP5 acid phosphatase 5, tartrate resistant
ADGRG6 adhesion G protein-coupled receptor G6
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
ATP2A3 ATPase, Ca++ transporting, ubiquitous
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4
CALM1 calmodulin 1 (phosphorylase kinase, delta)
CHD7 chromodomain helicase DNA binding protein 7
CHL1 cell adhesion molecule L1-like
COL2A1 collagen, type II, alpha 1
DLL3 delta-like 3 (Drosophila)
EGR2 early growth response 2
ESR1 estrogen receptor 1
ESR2 estrogen receptor 2 (ER beta)
FGF2 fibroblast growth factor 2 (basic)
FGFR3 fibroblast growth factor receptor 3
GHR growth hormone receptor
GPER1 G protein-coupled estrogen receptor 1
GPR50 G protein-coupled receptor 50
HTR1A 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled
HTR1B 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled
IGF1 insulin-like growth factor 1 (somatomedin C)
IGF1R insulin-like growth factor 1 receptor
IL17RC interleukin 17 receptor C
IL6 interleukin 6
LAPTM4B lysosomal protein transmembrane 4 beta
LBX1 ladybird homeobox 1
LCT lactase
LEP leptin
LEPR leptin receptor
LHX3 LIM homeobox 3
LOX lysyl oxidase
LOXL1 lysyl oxidase-like 1
LOXL2 lysyl oxidase-like 2
LOXL3 lysyl oxidase-like 3
LOXL4 lysyl oxidase-like 4
MATN1 matrilin 1, cartilage matrix protein
MMP3 matrix metallopeptidase 3
MTNR1A melatonin receptor 1A
MTNR1B melatonin receptor 1B
NTF3 neurotrophin 3
PRX periaxin
RIN2 Ras and Rab interactor 2
ROBO3 roundabout, axon guidance receptor, homolog 3 (Drosophila)
RORA RAR-related orphan receptor A
RUNX2 runt-related transcription factor 2
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SH3GL1 SH3-domain GRB2-like 1
SHOX short stature homeobox
SIM2 single-minded family bHLH transcription factor 2
TBX6 T-box 6
TGFB1 transforming growth factor, beta 1
TIMP2 TIMP metallopeptidase inhibitor 2
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11
TPH1 tryptophan hydroxylase 1
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
WNT3A wingless-type MMTV integration site family, member 3A