| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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198 genes differentially expressed following the scopolamine-3018 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABHD2 | abhydrolase domain containing 2 |
| ACVR1B | activin A receptor, type IB |
| ADAM28 | ADAM metallopeptidase domain 28 |
| ADIRF | adipogenesis regulatory factor |
| ADRB1 | adrenoceptor beta 1 |
| AICDA | activation-induced cytidine deaminase |
| ANGPT4 | angiopoietin 4 |
| APOBEC1 | apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1 |
| APOD | apolipoprotein D |
| ARG1 | arginase 1 |
| ATP2B3 | ATPase, Ca++ transporting, plasma membrane 3 |
| B9D2 | B9 protein domain 2 |
| BCAS3 | breast carcinoma amplified sequence 3 |
| BPY2 | basic charge, Y-linked, 2 |
| C17ORF59 | chromosome 17 open reading frame 59 |
| CADM4 | cell adhesion molecule 4 |
| CAMP | cathelicidin antimicrobial peptide |
| CAV2 | caveolin 2 |
| CCDC70 | coiled-coil domain containing 70 |
| CCL18 | chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated) |
| CD177 | CD177 molecule |
| CD300C | CD300c molecule |
| CDC42EP4 | CDC42 effector protein (Rho GTPase binding) 4 |
| CDK19 | cyclin-dependent kinase 19 |
| CES3 | carboxylesterase 3 |
| CMAHP | cytidine monophospho-N-acetylneuraminic acid hydroxylase, pseudogene |
| COL4A3 | collagen, type IV, alpha 3 (Goodpasture antigen) |
| CRAT | carnitine O-acetyltransferase |
| CST8 | cystatin 8 (cystatin-related epididymal specific) |
| CXCR3 | chemokine (C-X-C motif) receptor 3 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 |
| DESI2 | desumoylating isopeptidase 2 |
| DSC3 | desmocollin 3 |
| DTX2P1-UPK3BP1-PMS2P11 | DTX2P1-UPK3BP1-PMS2P11 readthrough transcribed pseudogene |
| EDDM3B | epididymal protein 3B |
| EGOT | eosinophil granule ontogeny transcript (non-protein coding) |
| EPHB2 | EPH receptor B2 |
| EXT1 | exostosin glycosyltransferase 1 |
| FGF16 | fibroblast growth factor 16 |
| FGF20 | fibroblast growth factor 20 |
| GABRG3 | gamma-aminobutyric acid (GABA) A receptor, gamma 3 |
| GIF | gastric intrinsic factor (vitamin B synthesis) |
| GPM6B | glycoprotein M6B |
| HLA-DPA1 | major histocompatibility complex, class II, DP alpha 1 |
| HOXA1 | homeobox A1 |
| HTR1B | 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled |
| IBA57 | IBA57, iron-sulfur cluster assembly homolog (S. cerevisiae) |
| IFI6 | interferon, alpha-inducible protein 6 |
| IGFBP5 | insulin-like growth factor binding protein 5 |
| IGL | immunoglobulin lambda locus |
| IGLL1 | immunoglobulin lambda-like polypeptide 1 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 |
| KCNG1 | potassium channel, voltage gated modifier subfamily G, member 1 |
| KIF1C | kinesin family member 1C |
| LEF1 | lymphoid enhancer-binding factor 1 |
| LHX1 | LIM homeobox 1 |
| LRRC48 | leucine rich repeat containing 48 |
| MAG | myelin associated glycoprotein |
| MEP1B | meprin A, beta |
| MOB3B | MOB kinase activator 3B |
| MST1 | macrophage stimulating 1 |
| NCAM1 | neural cell adhesion molecule 1 |
| NDRG2 | NDRG family member 2 |
| NOX1 | NADPH oxidase 1 |
| OPLAH | 5-oxoprolinase (ATP-hydrolysing) |
| OPTN | optineurin |
| PCDH9 | protocadherin 9 |
| POM121L9P | POM121 transmembrane nucleoporin-like 9, pseudogene |
| POU6F2 | POU class 6 homeobox 2 |
| PRDX2 | peroxiredoxin 2 |
| PVT1 | Pvt1 oncogene (non-protein coding) |
| RARRES2 | retinoic acid receptor responder (tazarotene induced) 2 |
| RCE1 | Ras converting CAAX endopeptidase 1 |
| RPL7 | ribosomal protein L7 |
| RTEL1 | regulator of telomere elongation helicase 1 |
| SFTPA2 | surfactant protein A2 |
| SLAMF7 | SLAM family member 7 |
| SLC12A8 | solute carrier family 12, member 8 |
| SLC22A1 | solute carrier family 22 (organic cation transporter), member 1 |
| SLC22A7 | solute carrier family 22 (organic anion transporter), member 7 |
| SLC23A2 | solute carrier family 23 (ascorbic acid transporter), member 2 |
| SLC4A8 | solute carrier family 4, sodium bicarbonate cotransporter, member 8 |
| SLC6A20 | solute carrier family 6 (proline IMINO transporter), member 20 |
| SLCO2A1 | solute carrier organic anion transporter family, member 2A1 |
| SLMO1 | slowmo homolog 1 (Drosophila) |
| SULT1E1 | sulfotransferase family 1E, estrogen-preferring, member 1 |
| TACR1 | tachykinin receptor 1 |
| TAP2 | transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) |
| TAS2R14 | taste receptor, type 2, member 14 |
| TAS2R4 | taste receptor, type 2, member 4 |
| TDRD12 | tudor domain containing 12 |
| TEAD3 | TEA domain family member 3 |
| TONSL | tonsoku-like, DNA repair protein |
| TRD | T cell receptor delta locus |
| UGT2B17 | UDP glucuronosyltransferase 2 family, polypeptide B17 |
| VCX2 | variable charge, X-linked 2 |
| WNT8B | wingless-type MMTV integration site family, member 8B |
| ZNF225 | zinc finger protein 225 |
| ZSCAN32 | zinc finger and SCAN domain containing 32 |
| Symbol | Name |
|---|---|
| ABCC2 | ATP-binding cassette, sub-family C (CFTR/MRP), member 2 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase |
| ACADSB | acyl-CoA dehydrogenase, short/branched chain |
| ADORA3 | adenosine A3 receptor |
| ANO2 | anoctamin 2, calcium activated chloride channel |
| ANXA2P3 | annexin A2 pseudogene 3 |
| APBB1IP | amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein |
| ASPSCR1 | alveolar soft part sarcoma chromosome region, candidate 1 |
| B4GALT2 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2 |
| BAG4 | BCL2-associated athanogene 4 |
| BTBD18 | BTB (POZ) domain containing 18 |
| BTF3P11 | basic transcription factor 3 pseudogene 11 |
| C1ORF159 | chromosome 1 open reading frame 159 |
| C3ORF14 | chromosome 3 open reading frame 14 |
| C8A | complement component 8, alpha polypeptide |
| CAMKMT | calmodulin-lysine N-methyltransferase |
| CASS4 | Cas scaffolding protein family member 4 |
| CD37 | CD37 molecule |
| CD79A | CD79a molecule, immunoglobulin-associated alpha |
| CDK20 | cyclin-dependent kinase 20 |
| CDKL1 | cyclin-dependent kinase-like 1 (CDC2-related kinase) |
| CEP131 | centrosomal protein 131kDa |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CHST4 | carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 4 |
| CLCN5 | chloride channel, voltage-sensitive 5 |
| CNR2 | cannabinoid receptor 2 (macrophage) |
| COPG2IT1 | COPG2 imprinted transcript 1 (non-protein coding) |
| CYP17A1 | cytochrome P450, family 17, subfamily A, polypeptide 1 |
| DCAF13 | DDB1 and CUL4 associated factor 13 |
| DDX31 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 31 |
| DDX58 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 |
| DZANK1 | double zinc ribbon and ankyrin repeat domains 1 |
| FBXL7 | F-box and leucine-rich repeat protein 7 |
| GABRA2 | gamma-aminobutyric acid (GABA) A receptor, alpha 2 |
| GABRA4 | gamma-aminobutyric acid (GABA) A receptor, alpha 4 |
| GABRR2 | gamma-aminobutyric acid (GABA) A receptor, rho 2 |
| GALNT6 | polypeptide N-acetylgalactosaminyltransferase 6 |
| GAREM | GRB2 associated, regulator of MAPK1 |
| GIT1 | G protein-coupled receptor kinase interacting ArfGAP 1 |
| GLRA1 | glycine receptor, alpha 1 |
| GPATCH2L | G patch domain containing 2-like |
| GPR35 | G protein-coupled receptor 35 |
| GSDMD | gasdermin D |
| HIST1H2AI | histone cluster 1, H2ai |
| HOXA6 | homeobox A6 |
| HOXC10 | homeobox C10 |
| HOXC8 | homeobox C8 |
| IBSP | integrin-binding sialoprotein |
| IGH | immunoglobulin heavy locus |
| INPP5E | inositol polyphosphate-5-phosphatase, 72 kDa |
| IRX5 | iroquois homeobox 5 |
| KANSL1L | KAT8 regulatory NSL complex subunit 1-like |
| KIAA0753 | KIAA0753 |
| MUC2 | mucin 2, oligomeric mucus/gel-forming |
| MXD3 | MAX dimerization protein 3 |
| NCS1 | neuronal calcium sensor 1 |
| NNAT | neuronatin |
| PDE7B | phosphodiesterase 7B |
| PFN2 | profilin 2 |
| PLA2G12A | phospholipase A2, group XIIA |
| PLA2G7 | phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) |
| PMFBP1 | polyamine modulated factor 1 binding protein 1 |
| POLH | polymerase (DNA directed), eta |
| PRDM12 | PR domain containing 12 |
| PRDM13 | PR domain containing 13 |
| PRF1 | perforin 1 (pore forming protein) |
| RAP1GAP2 | RAP1 GTPase activating protein 2 |
| RBFOX1 | RNA binding protein, fox-1 homolog (C. elegans) 1 |
| RPL23AP32 | ribosomal protein L23a pseudogene 32 |
| SAV1 | salvador family WW domain containing protein 1 |
| SCUBE3 | signal peptide, CUB domain, EGF-like 3 |
| SFRP5 | secreted frizzled-related protein 5 |
| SH2D4A | SH2 domain containing 4A |
| SIT1 | signaling threshold regulating transmembrane adaptor 1 |
| SOX12 | SRY (sex determining region Y)-box 12 |
| SPATA2L | spermatogenesis associated 2-like |
| SRPX | sushi-repeat containing protein, X-linked |
| STAG3L4 | stromal antigen 3-like 4 (pseudogene) |
| STEAP1 | six transmembrane epithelial antigen of the prostate 1 |
| STX5 | syntaxin 5 |
| TCTA | T-cell leukemia translocation altered |
| TCTN1 | tectonic family member 1 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 |
| TLR8 | toll-like receptor 8 |
| TMEM180 | transmembrane protein 180 |
| TRIM68 | tripartite motif containing 68 |
| TRPC5 | transient receptor potential cation channel, subfamily C, member 5 |
| TTC23 | tetratricopeptide repeat domain 23 |
| TUBA3C | tubulin, alpha 3c |
| TWIST1 | twist family bHLH transcription factor 1 |
| VHL | von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase |
| WT1-AS | WT1 antisense RNA |
| ZDHHC14 | zinc finger, DHHC-type containing 14 |
| ZFP30 | ZFP30 zinc finger protein |
| ZKSCAN8 | zinc finger with KRAB and SCAN domains 8 |
| ZNF10 | zinc finger protein 10 |
| ZNF286A | zinc finger protein 286A |
| ZNF668 | zinc finger protein 668 |
| ZNF675 | zinc finger protein 675 |