| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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196 genes differentially expressed following the scopolamine-3357 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADAMTS12 | ADAM metallopeptidase with thrombospondin type 1 motif, 12 |
| ANO2 | anoctamin 2, calcium activated chloride channel |
| ARID1A | AT rich interactive domain 1A (SWI-like) |
| ATG10 | autophagy related 10 |
| B3GNTL1 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like 1 |
| BCL2L10 | BCL2-like 10 (apoptosis facilitator) |
| BTF3P11 | basic transcription factor 3 pseudogene 11 |
| C19ORF57 | chromosome 19 open reading frame 57 |
| CAMK4 | calcium/calmodulin-dependent protein kinase IV |
| CASP1 | caspase 1, apoptosis-related cysteine peptidase |
| CD1E | CD1e molecule |
| CD22 | CD22 molecule |
| CD7 | CD7 molecule |
| CDK13 | cyclin-dependent kinase 13 |
| CHRNA3 | cholinergic receptor, nicotinic, alpha 3 (neuronal) |
| CLCA1 | chloride channel accessory 1 |
| CNR2 | cannabinoid receptor 2 (macrophage) |
| CRISP2 | cysteine-rich secretory protein 2 |
| DEAF1 | DEAF1 transcription factor |
| DEFB126 | defensin, beta 126 |
| DOK5 | docking protein 5 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A |
| EDA | ectodysplasin A |
| EMP3 | epithelial membrane protein 3 |
| FN1 | fibronectin 1 |
| FRAS1 | Fraser extracellular matrix complex subunit 1 |
| FSHB | follicle stimulating hormone, beta polypeptide |
| GAS7 | growth arrest-specific 7 |
| GPC1 | glypican 1 |
| GPRIN2 | G protein regulated inducer of neurite outgrowth 2 |
| HAB1 | B1 for mucin |
| HAL | histidine ammonia-lyase |
| HBB | hemoglobin, beta |
| HDAC6 | histone deacetylase 6 |
| HYAL3 | hyaluronoglucosaminidase 3 |
| ID4 | inhibitor of DNA binding 4, dominant negative helix-loop-helix protein |
| IGFALS | insulin-like growth factor binding protein, acid labile subunit |
| IGHD | immunoglobulin heavy constant delta |
| IL1RN | interleukin 1 receptor antagonist |
| IL2 | interleukin 2 |
| ITGA8 | integrin, alpha 8 |
| ITGBL1 | integrin, beta-like 1 (with EGF-like repeat domains) |
| KHDRBS3 | KH domain containing, RNA binding, signal transduction associated 3 |
| LAMB4 | laminin, beta 4 |
| LGALS4 | lectin, galactoside-binding, soluble, 4 |
| LRCH4 | leucine-rich repeats and calponin homology (CH) domain containing 4 |
| LRRC17 | leucine rich repeat containing 17 |
| MAG | myelin associated glycoprotein |
| MAGEA5 | melanoma antigen family A5 |
| MAPK8IP1 | mitogen-activated protein kinase 8 interacting protein 1 |
| MEF2D | myocyte enhancer factor 2D |
| MEG3 | maternally expressed 3 (non-protein coding) |
| MIER2 | mesoderm induction early response 1, family member 2 |
| MOB3B | MOB kinase activator 3B |
| MOBP | myelin-associated oligodendrocyte basic protein |
| MXRA8 | matrix-remodelling associated 8 |
| NCKIPSD | NCK interacting protein with SH3 domain |
| NCR3 | natural cytotoxicity triggering receptor 3 |
| NEUROD1 | neuronal differentiation 1 |
| NOP16 | NOP16 nucleolar protein |
| NRF1 | nuclear respiratory factor 1 |
| PDE10A | phosphodiesterase 10A |
| PDE3B | phosphodiesterase 3B, cGMP-inhibited |
| PICK1 | protein interacting with PRKCA 1 |
| PLK3 | polo-like kinase 3 |
| PMS2P3 | postmeiotic segregation increased 2 pseudogene 3 |
| PQLC3 | PQ loop repeat containing 3 |
| PRB3 | proline-rich protein BstNI subfamily 3 |
| PRDX2 | peroxiredoxin 2 |
| PRKCA | protein kinase C, alpha |
| RBFOX1 | RNA binding protein, fox-1 homolog (C. elegans) 1 |
| RPS6KA6 | ribosomal protein S6 kinase, 90kDa, polypeptide 6 |
| SAMD9 | sterile alpha motif domain containing 9 |
| SH3BP2 | SH3-domain binding protein 2 |
| SIPA1 | signal-induced proliferation-associated 1 |
| SLC12A3 | solute carrier family 12 (sodium/chloride transporter), member 3 |
| SLC1A4 | solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 |
| SLC35E2 | solute carrier family 35, member E2 |
| SLC7A8 | solute carrier family 7 (amino acid transporter light chain, L system), member 8 |
| SNTG1 | syntrophin, gamma 1 |
| SPACA1 | sperm acrosome associated 1 |
| SPEG | SPEG complex locus |
| SPOCK2 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2 |
| SPRR1B | small proline-rich protein 1B |
| SPTLC3 | serine palmitoyltransferase, long chain base subunit 3 |
| TAT | tyrosine aminotransferase |
| TGFB2 | transforming growth factor, beta 2 |
| TJAP1 | tight junction associated protein 1 (peripheral) |
| TOR4A | torsin family 4, member A |
| TRIM10 | tripartite motif containing 10 |
| TRIM38 | tripartite motif containing 38 |
| VPS9D1 | VPS9 domain containing 1 |
| WDTC1 | WD and tetratricopeptide repeats 1 |
| WFDC2 | WAP four-disulfide core domain 2 |
| WSCD1 | WSC domain containing 1 |
| YY2 | YY2 transcription factor |
| ZNF3 | zinc finger protein 3 |
| ZNF76 | zinc finger protein 76 |
| Symbol | Name |
|---|---|
| ADAP2 | ArfGAP with dual PH domains 2 |
| ARID3A | AT rich interactive domain 3A (BRIGHT-like) |
| ARMCX2 | armadillo repeat containing, X-linked 2 |
| B3GNT3 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3 |
| B4GALT2 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2 |
| BAHCC1 | BAH domain and coiled-coil containing 1 |
| BCORL1 | BCL6 corepressor-like 1 |
| C11ORF80 | chromosome 11 open reading frame 80 |
| C12ORF4 | chromosome 12 open reading frame 4 |
| C1ORF56 | chromosome 1 open reading frame 56 |
| C9ORF40 | chromosome 9 open reading frame 40 |
| CACNA1H | calcium channel, voltage-dependent, T type, alpha 1H subunit |
| CBR4 | carbonyl reductase 4 |
| CD302 | CD302 molecule |
| CDC42EP1 | CDC42 effector protein (Rho GTPase binding) 1 |
| CSTA | cystatin A (stefin A) |
| CYP20A1 | cytochrome P450, family 20, subfamily A, polypeptide 1 |
| DEPTOR | DEP domain containing MTOR-interacting protein |
| DHX57 | DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57 |
| DIXDC1 | DIX domain containing 1 |
| DSCAM | Down syndrome cell adhesion molecule |
| EHHADH | enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase |
| ELOVL4 | ELOVL fatty acid elongase 4 |
| ENTPD7 | ectonucleoside triphosphate diphosphohydrolase 7 |
| ERCC4 | excision repair cross-complementation group 4 |
| FILIP1L | filamin A interacting protein 1-like |
| FLRT3 | fibronectin leucine rich transmembrane protein 3 |
| FOXC1 | forkhead box C1 |
| FOXD1 | forkhead box D1 |
| FOXI1 | forkhead box I1 |
| GINS4 | GINS complex subunit 4 (Sld5 homolog) |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HGSNAT | heparan-alpha-glucosaminide N-acetyltransferase |
| HIST1H2AJ | histone cluster 1, H2aj |
| HYI | hydroxypyruvate isomerase (putative) |
| IMPACT | impact RWD domain protein |
| KIAA0232 | KIAA0232 |
| KIF13B | kinesin family member 13B |
| LIN7A | lin-7 homolog A (C. elegans) |
| LNPEP | leucyl/cystinyl aminopeptidase |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 |
| MDN1 | MDN1, midasin homolog (yeast) |
| MICAL1 | microtubule associated monooxygenase, calponin and LIM domain containing 1 |
| MRM1 | mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae) |
| MTCP1 | mature T-cell proliferation 1 |
| MTERF4 | mitochondrial transcription termination factor 4 |
| NAV2 | neuron navigator 2 |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) |
| NUBPL | nucleotide binding protein-like |
| NUP62CL | nucleoporin 62kDa C-terminal like |
| OLFML3 | olfactomedin-like 3 |
| OPA3 | optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia) |
| PLCD1 | phospholipase C, delta 1 |
| PRODH | proline dehydrogenase (oxidase) 1 |
| PRRG4 | proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane) |
| RAD54L2 | RAD54-like 2 (S. cerevisiae) |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B |
| RNF219 | ring finger protein 219 |
| RPGRIP1L | RPGRIP1-like |
| RPL23AP32 | ribosomal protein L23a pseudogene 32 |
| RUNDC3B | RUN domain containing 3B |
| SCAI | suppressor of cancer cell invasion |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A |
| SEMA4D | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D |
| SH3BGR | SH3 domain binding glutamate-rich protein |
| SIRT6 | sirtuin 6 |
| SLC12A8 | solute carrier family 12, member 8 |
| SLC8B1 | solute carrier family 8 (sodium/lithium/calcium exchanger), member B1 |
| SMCO4 | single-pass membrane protein with coiled-coil domains 4 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase |
| SOX12 | SRY (sex determining region Y)-box 12 |
| SUZ12P1 | suppressor of zeste 12 homolog pseudogene 1 |
| SYBU | syntabulin (syntaxin-interacting) |
| TBC1D2 | TBC1 domain family, member 2 |
| THNSL1 | threonine synthase-like 1 (S. cerevisiae) |
| TIMM50 | translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) |
| TMEM62 | transmembrane protein 62 |
| TMSB15A | thymosin beta 15a |
| TNFSF9 | tumor necrosis factor (ligand) superfamily, member 9 |
| TPST2 | tyrosylprotein sulfotransferase 2 |
| TRAIP | TRAF interacting protein |
| TRAPPC13 | trafficking protein particle complex 13 |
| TRIM16 | tripartite motif containing 16 |
| TRMT1L | tRNA methyltransferase 1 homolog (S. cerevisiae)-like |
| TSPYL2 | TSPY-like 2 |
| TUBA3C | tubulin, alpha 3c |
| UPP1 | uridine phosphorylase 1 |
| USP19 | ubiquitin specific peptidase 19 |
| VLDLR | very low density lipoprotein receptor |
| ZBTB3 | zinc finger and BTB domain containing 3 |
| ZBTB39 | zinc finger and BTB domain containing 39 |
| ZBTB6 | zinc finger and BTB domain containing 6 |
| ZFHX2 | zinc finger homeobox 2 |
| ZNF652 | zinc finger protein 652 |
| ZNF665 | zinc finger protein 665 |
| ZNF74 | zinc finger protein 74 |
| ZNF862 | zinc finger protein 862 |