scopolamine-3357 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the scopolamine-3357 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAMTS12 ADAM metallopeptidase with thrombospondin type 1 motif, 12
ANO2 anoctamin 2, calcium activated chloride channel
ARID1A AT rich interactive domain 1A (SWI-like)
ATG10 autophagy related 10
B3GNTL1 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like 1
BCL2L10 BCL2-like 10 (apoptosis facilitator)
BTF3P11 basic transcription factor 3 pseudogene 11
C19ORF57 chromosome 19 open reading frame 57
CAMK4 calcium/calmodulin-dependent protein kinase IV
CASP1 caspase 1, apoptosis-related cysteine peptidase
CD1E CD1e molecule
CD22 CD22 molecule
CD7 CD7 molecule
CDK13 cyclin-dependent kinase 13
CHRNA3 cholinergic receptor, nicotinic, alpha 3 (neuronal)
CLCA1 chloride channel accessory 1
CNR2 cannabinoid receptor 2 (macrophage)
CRISP2 cysteine-rich secretory protein 2
DEAF1 DEAF1 transcription factor
DEFB126 defensin, beta 126
DOK5 docking protein 5
DYRK1A dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A
EDA ectodysplasin A
EMP3 epithelial membrane protein 3
FN1 fibronectin 1
FRAS1 Fraser extracellular matrix complex subunit 1
FSHB follicle stimulating hormone, beta polypeptide
GAS7 growth arrest-specific 7
GPC1 glypican 1
GPRIN2 G protein regulated inducer of neurite outgrowth 2
HAB1 B1 for mucin
HAL histidine ammonia-lyase
HBB hemoglobin, beta
HDAC6 histone deacetylase 6
HYAL3 hyaluronoglucosaminidase 3
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
IGFALS insulin-like growth factor binding protein, acid labile subunit
IGHD immunoglobulin heavy constant delta
IL1RN interleukin 1 receptor antagonist
IL2 interleukin 2
ITGA8 integrin, alpha 8
ITGBL1 integrin, beta-like 1 (with EGF-like repeat domains)
KHDRBS3 KH domain containing, RNA binding, signal transduction associated 3
LAMB4 laminin, beta 4
LGALS4 lectin, galactoside-binding, soluble, 4
LRCH4 leucine-rich repeats and calponin homology (CH) domain containing 4
LRRC17 leucine rich repeat containing 17
MAG myelin associated glycoprotein
MAGEA5 melanoma antigen family A5
MAPK8IP1 mitogen-activated protein kinase 8 interacting protein 1
MEF2D myocyte enhancer factor 2D
MEG3 maternally expressed 3 (non-protein coding)
MIER2 mesoderm induction early response 1, family member 2
MOB3B MOB kinase activator 3B
MOBP myelin-associated oligodendrocyte basic protein
MXRA8 matrix-remodelling associated 8
NCKIPSD NCK interacting protein with SH3 domain
NCR3 natural cytotoxicity triggering receptor 3
NEUROD1 neuronal differentiation 1
NOP16 NOP16 nucleolar protein
NRF1 nuclear respiratory factor 1
PDE10A phosphodiesterase 10A
PDE3B phosphodiesterase 3B, cGMP-inhibited
PICK1 protein interacting with PRKCA 1
PLK3 polo-like kinase 3
PMS2P3 postmeiotic segregation increased 2 pseudogene 3
PQLC3 PQ loop repeat containing 3
PRB3 proline-rich protein BstNI subfamily 3
PRDX2 peroxiredoxin 2
PRKCA protein kinase C, alpha
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1
RPS6KA6 ribosomal protein S6 kinase, 90kDa, polypeptide 6
SAMD9 sterile alpha motif domain containing 9
SH3BP2 SH3-domain binding protein 2
SIPA1 signal-induced proliferation-associated 1
SLC12A3 solute carrier family 12 (sodium/chloride transporter), member 3
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
SLC35E2 solute carrier family 35, member E2
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
SNTG1 syntrophin, gamma 1
SPACA1 sperm acrosome associated 1
SPEG SPEG complex locus
SPOCK2 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
SPRR1B small proline-rich protein 1B
SPTLC3 serine palmitoyltransferase, long chain base subunit 3
TAT tyrosine aminotransferase
TGFB2 transforming growth factor, beta 2
TJAP1 tight junction associated protein 1 (peripheral)
TOR4A torsin family 4, member A
TRIM10 tripartite motif containing 10
TRIM38 tripartite motif containing 38
VPS9D1 VPS9 domain containing 1
WDTC1 WD and tetratricopeptide repeats 1
WFDC2 WAP four-disulfide core domain 2
WSCD1 WSC domain containing 1
YY2 YY2 transcription factor
ZNF3 zinc finger protein 3
ZNF76 zinc finger protein 76

decreased expression

Symbol Name
ADAP2 ArfGAP with dual PH domains 2
ARID3A AT rich interactive domain 3A (BRIGHT-like)
ARMCX2 armadillo repeat containing, X-linked 2
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3
B4GALT2 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2
BAHCC1 BAH domain and coiled-coil containing 1
BCORL1 BCL6 corepressor-like 1
C11ORF80 chromosome 11 open reading frame 80
C12ORF4 chromosome 12 open reading frame 4
C1ORF56 chromosome 1 open reading frame 56
C9ORF40 chromosome 9 open reading frame 40
CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit
CBR4 carbonyl reductase 4
CD302 CD302 molecule
CDC42EP1 CDC42 effector protein (Rho GTPase binding) 1
CSTA cystatin A (stefin A)
CYP20A1 cytochrome P450, family 20, subfamily A, polypeptide 1
DEPTOR DEP domain containing MTOR-interacting protein
DHX57 DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57
DIXDC1 DIX domain containing 1
DSCAM Down syndrome cell adhesion molecule
EHHADH enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase
ELOVL4 ELOVL fatty acid elongase 4
ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7
ERCC4 excision repair cross-complementation group 4
FILIP1L filamin A interacting protein 1-like
FLRT3 fibronectin leucine rich transmembrane protein 3
FOXC1 forkhead box C1
FOXD1 forkhead box D1
FOXI1 forkhead box I1
GINS4 GINS complex subunit 4 (Sld5 homolog)
GUSBP3 glucuronidase, beta pseudogene 3
HGSNAT heparan-alpha-glucosaminide N-acetyltransferase
HIST1H2AJ histone cluster 1, H2aj
HYI hydroxypyruvate isomerase (putative)
IMPACT impact RWD domain protein
KIAA0232 KIAA0232
KIF13B kinesin family member 13B
LIN7A lin-7 homolog A (C. elegans)
LNPEP leucyl/cystinyl aminopeptidase
MBOAT2 membrane bound O-acyltransferase domain containing 2
MDN1 MDN1, midasin homolog (yeast)
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
MTCP1 mature T-cell proliferation 1
MTERF4 mitochondrial transcription termination factor 4
NAV2 neuron navigator 2
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NUBPL nucleotide binding protein-like
NUP62CL nucleoporin 62kDa C-terminal like
OLFML3 olfactomedin-like 3
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
PLCD1 phospholipase C, delta 1
PRODH proline dehydrogenase (oxidase) 1
PRRG4 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane)
RAD54L2 RAD54-like 2 (S. cerevisiae)
RALGPS2 Ral GEF with PH domain and SH3 binding motif 2
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RNF219 ring finger protein 219
RPGRIP1L RPGRIP1-like
RPL23AP32 ribosomal protein L23a pseudogene 32
RUNDC3B RUN domain containing 3B
SCAI suppressor of cancer cell invasion
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SH3BGR SH3 domain binding glutamate-rich protein
SIRT6 sirtuin 6
SLC12A8 solute carrier family 12, member 8
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
SMCO4 single-pass membrane protein with coiled-coil domains 4
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase
SOX12 SRY (sex determining region Y)-box 12
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
SYBU syntabulin (syntaxin-interacting)
TBC1D2 TBC1 domain family, member 2
THNSL1 threonine synthase-like 1 (S. cerevisiae)
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TMEM62 transmembrane protein 62
TMSB15A thymosin beta 15a
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9
TPST2 tyrosylprotein sulfotransferase 2
TRAIP TRAF interacting protein
TRAPPC13 trafficking protein particle complex 13
TRIM16 tripartite motif containing 16
TRMT1L tRNA methyltransferase 1 homolog (S. cerevisiae)-like
TSPYL2 TSPY-like 2
TUBA3C tubulin, alpha 3c
UPP1 uridine phosphorylase 1
USP19 ubiquitin specific peptidase 19
VLDLR very low density lipoprotein receptor
ZBTB3 zinc finger and BTB domain containing 3
ZBTB39 zinc finger and BTB domain containing 39
ZBTB6 zinc finger and BTB domain containing 6
ZFHX2 zinc finger homeobox 2
ZNF652 zinc finger protein 652
ZNF665 zinc finger protein 665
ZNF74 zinc finger protein 74
ZNF862 zinc finger protein 862