scopolamine-4219 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the scopolamine-4219 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group)
ABO ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase)
ADGB androglobin
AGRP agouti related neuropeptide
AKAP13 A kinase (PRKA) anchor protein 13
AOAH acyloxyacyl hydrolase (neutrophil)
APOB apolipoprotein B
ASCL1 achaete-scute family bHLH transcription factor 1
BICD1 bicaudal D homolog 1 (Drosophila)
BMPR1B bone morphogenetic protein receptor, type IB
C19ORF26 chromosome 19 open reading frame 26
CADM4 cell adhesion molecule 4
CAMK2B calcium/calmodulin-dependent protein kinase II beta
CCL21 chemokine (C-C motif) ligand 21
CD177 CD177 molecule
CD72 CD72 molecule
CDK19 cyclin-dependent kinase 19
CEL carboxyl ester lipase
CELSR1 cadherin, EGF LAG seven-pass G-type receptor 1
CES3 carboxylesterase 3
CLEC10A C-type lectin domain family 10, member A
CLTA clathrin, light chain A
CRH corticotropin releasing hormone
CSF1 colony stimulating factor 1 (macrophage)
CSN2 casein beta
CST2 cystatin SA
CXXC4 CXXC finger protein 4
DKKL1 dickkopf-like 1
DLGAP1 discs, large (Drosophila) homolog-associated protein 1
DUX4L8 double homeobox 4 like 8
DYRK1A dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A
EDN3 endothelin 3
EPHA3 EPH receptor A3
EPHB1 EPH receptor B1
EPS8L1 EPS8-like 1
FAM163A family with sequence similarity 163, member A
FAM212B family with sequence similarity 212, member B
GABRQ gamma-aminobutyric acid (GABA) A receptor, theta
GALR1 galanin receptor 1
GLI2 GLI family zinc finger 2
GRIA3 glutamate receptor, ionotropic, AMPA 3
GRM4 glutamate receptor, metabotropic 4
HIST1H4G histone cluster 1, H4g
HLA-DOA major histocompatibility complex, class II, DO alpha
HSPB6 heat shock protein, alpha-crystallin-related, B6
HTR5A 5-hydroxytryptamine (serotonin) receptor 5A, G protein-coupled
IBSP integrin-binding sialoprotein
IGL immunoglobulin lambda locus
IL37 interleukin 37
INADL InaD-like (Drosophila)
JUND jun D proto-oncogene
KCNE2 potassium channel, voltage gated subfamily E regulatory beta subunit 2
KIR2DS4 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 4
KLK11 kallikrein-related peptidase 11
LILRA5 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 5
LRP1 low density lipoprotein receptor-related protein 1
LUM lumican
MFAP5 microfibrillar associated protein 5
MPPE1 metallophosphoesterase 1
MYCNOS MYCN opposite strand
MYH13 myosin, heavy chain 13, skeletal muscle
N4BP2L1 NEDD4 binding protein 2-like 1
NEURL1 neuralized E3 ubiquitin protein ligase 1
NF1 neurofibromin 1
NMUR1 neuromedin U receptor 1
NTF3 neurotrophin 3
PDPN podoplanin
PEX3 peroxisomal biogenesis factor 3
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1
PLVAP plasmalemma vesicle associated protein
POFUT2 protein O-fucosyltransferase 2
POU3F1 POU class 3 homeobox 1
PPARD peroxisome proliferator-activated receptor delta
PPP1R37 protein phosphatase 1, regulatory subunit 37
PTGDS prostaglandin D2 synthase 21kDa (brain)
PTRF polymerase I and transcript release factor
PYY peptide YY
R3HDM1 R3H domain containing 1
RASGRF1 Ras protein-specific guanine nucleotide-releasing factor 1
RGR retinal G protein coupled receptor
RIC3 RIC3 acetylcholine receptor chaperone
RUNDC3A RUN domain containing 3A
RUNX1 runt-related transcription factor 1
SEZ6L seizure related 6 homolog (mouse)-like
SLC12A5 solute carrier family 12 (potassium/chloride transporter), member 5
SLC17A2 solute carrier family 17, member 2
SLCO1B1 solute carrier organic anion transporter family, member 1B1
SOX5 SRY (sex determining region Y)-box 5
STAR steroidogenic acute regulatory protein
TCL6 T-cell leukemia/lymphoma 6 (non-protein coding)
TMEM212 transmembrane protein 212
TMPRSS11E transmembrane protease, serine 11E
TRGV5 T cell receptor gamma variable 5
TRIM3 tripartite motif containing 3
USP22 ubiquitin specific peptidase 22
VCX2 variable charge, X-linked 2
WISP2 WNT1 inducible signaling pathway protein 2
ZNF223 zinc finger protein 223
ZNF280A zinc finger protein 280A

decreased expression

Symbol Name
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase
ACTG2 actin, gamma 2, smooth muscle, enteric
ADPRM ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent
AFAP1 actin filament associated protein 1
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
ALS2CL ALS2 C-terminal like
ARL14 ADP-ribosylation factor-like 14
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila)
BAG4 BCL2-associated athanogene 4
BEND5 BEN domain containing 5
BEX1 brain expressed, X-linked 1
BGLAP bone gamma-carboxyglutamate (gla) protein
BRWD1 bromodomain and WD repeat domain containing 1
C4ORF19 chromosome 4 open reading frame 19
CA11 carbonic anhydrase XI
CDIPT CDP-diacylglycerol--inositol 3-phosphatidyltransferase
CEP112 centrosomal protein 112kDa
CHRDL1 chordin-like 1
CLDN11 claudin 11
CNIH3 cornichon family AMPA receptor auxiliary protein 3
CNNM4 cyclin and CBS domain divalent metal cation transport mediator 4
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
CTSO cathepsin O
CYP7B1 cytochrome P450, family 7, subfamily B, polypeptide 1
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6
DNAH7 dynein, axonemal, heavy chain 7
EGR2 early growth response 2
ETAA1 Ewing tumor-associated antigen 1
EXOC6B exocyst complex component 6B
FAM169A family with sequence similarity 169, member A
FAM69A family with sequence similarity 69, member A
FGF13 fibroblast growth factor 13
FUT1 fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group)
GCNT2 glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
GID4 GID complex subunit 4
GMEB1 glucocorticoid modulatory element binding protein 1
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide
GPATCH2L G patch domain containing 2-like
GTF2I general transcription factor IIi
HIST1H3C histone cluster 1, H3c
HOXA1 homeobox A1
IFT54 intraflagellar transport 54
IGSF3 immunoglobulin superfamily, member 3
IL17RA interleukin 17 receptor A
IL17RB interleukin 17 receptor B
INCENP inner centromere protein antigens 135/155kDa
INPP5E inositol polyphosphate-5-phosphatase, 72 kDa
KCTD20 potassium channel tetramerization domain containing 20
KIAA0753 KIAA0753
KRT86 keratin 86, type II
LOC100286895 cell division cycle 27 homolog pseudogene
LOC730101 uncharacterized LOC730101
LPPR4 lipid phosphate phosphatase-related protein type 4
LRRC6 leucine rich repeat containing 6
MBTPS2 membrane-bound transcription factor peptidase, site 2
MGC12488
MRPL41 mitochondrial ribosomal protein L41
MTHFD2L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like
MTR 5-methyltetrahydrofolate-homocysteine methyltransferase
MYOZ3 myozenin 3
NCS1 neuronal calcium sensor 1
NDP Norrie disease (pseudoglioma)
NDRG4 NDRG family member 4
NLGN1 neuroligin 1
NR1H3 nuclear receptor subfamily 1, group H, member 3
NSUN6 NOP2/Sun domain family, member 6
OSGEPL1 O-sialoglycoprotein endopeptidase-like 1
OSMR oncostatin M receptor
PAK3 p21 protein (Cdc42/Rac)-activated kinase 3
PAK6 p21 protein (Cdc42/Rac)-activated kinase 6
PER3 period circadian clock 3
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent)
PLA2G7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
PLSCR4 phospholipid scramblase 4
POLR1B polymerase (RNA) I polypeptide B, 128kDa
PTK7 protein tyrosine kinase 7 (inactive)
QSER1 glutamine and serine rich 1
RAI2 retinoic acid induced 2
RP2 retinitis pigmentosa 2 (X-linked recessive)
RPL13P5 ribosomal protein L13 pseudogene 5
RPL23AP32 ribosomal protein L23a pseudogene 32
RRAGB Ras-related GTP binding B
RUNDC3B RUN domain containing 3B
SCG5 secretogranin V
SLITRK5 SLIT and NTRK-like family, member 5
SMEK2 SMEK homolog 2, suppressor of mek1 (Dictyostelium)
SPEG SPEG complex locus
SPRYD7 SPRY domain containing 7
TAGLN3 transgelin 3
TMEM242 transmembrane protein 242
TSPAN2 tetraspanin 2
TUBG2 tubulin, gamma 2
TWISTNB TWIST neighbor
VASH2 vasohibin 2
VGLL3 vestigial-like family member 3
WDR76 WD repeat domain 76
ZNF10 zinc finger protein 10
ZNF227 zinc finger protein 227
ZNF675 zinc finger protein 675