scopolamine-4803 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the scopolamine-4803 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AAK1 AP2 associated kinase 1
AHNAK2 AHNAK nucleoprotein 2
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
ALPI alkaline phosphatase, intestinal
APAF1 apoptotic peptidase activating factor 1
APC adenomatous polyposis coli
APLNR apelin receptor
ARHGAP1 Rho GTPase activating protein 1
ARHGAP33 Rho GTPase activating protein 33
B4GALT1 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1
BHLHE40 basic helix-loop-helix family, member e40
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase
CACNB4 calcium channel, voltage-dependent, beta 4 subunit
CALB2 calbindin 2
CAMK1 calcium/calmodulin-dependent protein kinase I
CAPRIN1 cell cycle associated protein 1
CARD14 caspase recruitment domain family, member 14
CD58 CD58 molecule
CHKB choline kinase beta
CLCA2 chloride channel accessory 2
CPNE7 copine VII
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
EIF2AK1 eukaryotic translation initiation factor 2-alpha kinase 1
FBXO38 F-box protein 38
FNDC3A fibronectin type III domain containing 3A
FNTB farnesyltransferase, CAAX box, beta
GNG13 guanine nucleotide binding protein (G protein), gamma 13
GP6 glycoprotein VI (platelet)
GPR3 G protein-coupled receptor 3
GPR4 G protein-coupled receptor 4
GRM1 glutamate receptor, metabotropic 1
HLA-F major histocompatibility complex, class I, F
HMGA1 high mobility group AT-hook 1
HOXB5 homeobox B5
HSPA12A heat shock 70kDa protein 12A
HTR1B 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled
IL2RA interleukin 2 receptor, alpha
IL33R interleukin 33 receptor
ITFG2 integrin alpha FG-GAP repeat containing 2
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3
KAT8 K(lysine) acetyltransferase 8
KBTBD11 kelch repeat and BTB (POZ) domain containing 11
LPCAT3 lysophosphatidylcholine acyltransferase 3
MAPK1 mitogen-activated protein kinase 1
MAPK11 mitogen-activated protein kinase 11
MSH6 mutS homolog 6
MTA2 metastasis associated 1 family, member 2
MVP major vault protein
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
OLFML2A olfactomedin-like 2A
PAX5 paired box 5
PCNXL2 pecanex-like 2 (Drosophila)
PDX1 pancreatic and duodenal homeobox 1
PIN1P1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 pseudogene 1
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PLLP plasmolipin
POLL polymerase (DNA directed), lambda
POPDC3 popeye domain containing 3
POT1 protection of telomeres 1
PPP4R4 protein phosphatase 4, regulatory subunit 4
PPP5C protein phosphatase 5, catalytic subunit
PTPRJ protein tyrosine phosphatase, receptor type, J
PVR poliovirus receptor
RAD51B RAD51 paralog B
RASL11B RAS-like, family 11, member B
RBMS2 RNA binding motif, single stranded interacting protein 2
REM1 RAS (RAD and GEM)-like GTP-binding 1
RPS3A ribosomal protein S3A
RRN3P1 RNA polymerase I transcription factor homolog (S. cerevisiae) pseudogene 1
SERHL2 serine hydrolase-like 2
SH3BP2 SH3-domain binding protein 2
SIGLEC6 sialic acid binding Ig-like lectin 6
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
SMAD5 SMAD family member 5
STRA6 stimulated by retinoic acid 6
SUGP1 SURP and G patch domain containing 1
SYN3 synapsin III
TAF6L TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa
TBL2 transducin (beta)-like 2
TBXA2R thromboxane A2 receptor
THBD thrombomodulin
THBS3 thrombospondin 3
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
TNS1 tensin 1
TP53I11 tumor protein p53 inducible protein 11
TRA2A transformer 2 alpha homolog (Drosophila)
TRIB2 tribbles pseudokinase 2
TRIM23 tripartite motif containing 23
TSC22D4 TSC22 domain family, member 4
TUBA3C tubulin, alpha 3c
USB1 U6 snRNA biogenesis 1
VPREB3 pre-B lymphocyte 3
WDFY3 WD repeat and FYVE domain containing 3
WNK1 WNK lysine deficient protein kinase 1
ZNF337 zinc finger protein 337
ZNF528 zinc finger protein 528

decreased expression

Symbol Name
ACTL8 actin-like 8
AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3
AHCTF1 AT hook containing transcription factor 1
ALOX12P2 arachidonate 12-lipoxygenase pseudogene 2
APOLD1 apolipoprotein L domain containing 1
ARHGAP5 Rho GTPase activating protein 5
ARNTL2 aryl hydrocarbon receptor nuclear translocator-like 2
BAHCC1 BAH domain and coiled-coil containing 1
BBS7 Bardet-Biedl syndrome 7
BCAS1 breast carcinoma amplified sequence 1
C22ORF29 chromosome 22 open reading frame 29
CD2AP CD2-associated protein
CENPO centromere protein O
CRYBG3 beta-gamma crystallin domain containing 3
CTNNBIP1 catenin, beta interacting protein 1
CUL9 cullin 9
CXADR coxsackie virus and adenovirus receptor
DGAT1 diacylglycerol O-acyltransferase 1
F3 coagulation factor III (thromboplastin, tissue factor)
FANCE Fanconi anemia, complementation group E
FBXL2 F-box and leucine-rich repeat protein 2
FGF23 fibroblast growth factor 23
GADD45G growth arrest and DNA-damage-inducible, gamma
GINS4 GINS complex subunit 4 (Sld5 homolog)
GLS2 glutaminase 2 (liver, mitochondrial)
GTF2H3 general transcription factor IIH, polypeptide 3, 34kDa
HAUS6 HAUS augmin-like complex, subunit 6
HDAC4 histone deacetylase 4
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5
HIST1H2AL histone cluster 1, H2al
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
HMOX1 heme oxygenase 1
IFI6 interferon, alpha-inducible protein 6
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IFT22 intraflagellar transport 22
IL17RA interleukin 17 receptor A
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
JUNB jun B proto-oncogene
KCNK12 potassium channel, two pore domain subfamily K, member 12
KHDRBS3 KH domain containing, RNA binding, signal transduction associated 3
KLHL26 kelch-like family member 26
KREMEN2 kringle containing transmembrane protein 2
LHX1 LIM homeobox 1
LINC00597 long intergenic non-protein coding RNA 597
LMNB1 lamin B1
LRCH1 leucine-rich repeats and calponin homology (CH) domain containing 1
LRFN3 leucine rich repeat and fibronectin type III domain containing 3
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
MFAP2 microfibrillar-associated protein 2
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1
MUL1 mitochondrial E3 ubiquitin protein ligase 1
NEUROD4 neuronal differentiation 4
NFE2L3 nuclear factor, erythroid 2-like 3
NRTN neurturin
ONECUT2 one cut homeobox 2
OR2F1 olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene)
PDLIM2 PDZ and LIM domain 2 (mystique)
PEX26 peroxisomal biogenesis factor 26
PIGQ phosphatidylinositol glycan anchor biosynthesis, class Q
PYCRL pyrroline-5-carboxylate reductase-like
QTRT1 queuine tRNA-ribosyltransferase 1
RFWD3 ring finger and WD repeat domain 3
RNF39 ring finger protein 39
RPL13P5 ribosomal protein L13 pseudogene 5
RPL23AP32 ribosomal protein L23a pseudogene 32
RPRD2 regulation of nuclear pre-mRNA domain containing 2
S100A2 S100 calcium binding protein A2
SAYSD1 SAYSVFN motif domain containing 1
SGPP1 sphingosine-1-phosphate phosphatase 1
SMEK2 SMEK homolog 2, suppressor of mek1 (Dictyostelium)
SND1-IT1 SND1 intronic transcript 1
SNX16 sorting nexin 16
SPAG4 sperm associated antigen 4
SPRY2 sprouty homolog 2 (Drosophila)
SPTLC3 serine palmitoyltransferase, long chain base subunit 3
STARD5 StAR-related lipid transfer (START) domain containing 5
SYNC syncoilin, intermediate filament protein
TAF13 TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa
TAOK1 TAO kinase 1
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TLN1 talin 1
TMEM45A transmembrane protein 45A
TNRC6B trinucleotide repeat containing 6B
TPCN1 two pore segment channel 1
TRPM4 transient receptor potential cation channel, subfamily M, member 4
TSGA10 testis specific, 10
TTBK2 tau tubulin kinase 2
TUBA3D tubulin, alpha 3d
UNC119 unc-119 homolog (C. elegans)
UPP1 uridine phosphorylase 1
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2
YEATS4 YEATS domain containing 4
ZBTB22 zinc finger and BTB domain containing 22
ZCWPW1 zinc finger, CW type with PWWP domain 1
ZNF134 zinc finger protein 134
ZNF219 zinc finger protein 219
ZNF329 zinc finger protein 329
ZNF652 zinc finger protein 652