| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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196 genes differentially expressed following the scopolamine-4803 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AAK1 | AP2 associated kinase 1 |
| AHNAK2 | AHNAK nucleoprotein 2 |
| AKR1B1 | aldo-keto reductase family 1, member B1 (aldose reductase) |
| ALPI | alkaline phosphatase, intestinal |
| APAF1 | apoptotic peptidase activating factor 1 |
| APC | adenomatous polyposis coli |
| APLNR | apelin receptor |
| ARHGAP1 | Rho GTPase activating protein 1 |
| ARHGAP33 | Rho GTPase activating protein 33 |
| B4GALT1 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 |
| BHLHE40 | basic helix-loop-helix family, member e40 |
| BTRC | beta-transducin repeat containing E3 ubiquitin protein ligase |
| CACNB4 | calcium channel, voltage-dependent, beta 4 subunit |
| CALB2 | calbindin 2 |
| CAMK1 | calcium/calmodulin-dependent protein kinase I |
| CAPRIN1 | cell cycle associated protein 1 |
| CARD14 | caspase recruitment domain family, member 14 |
| CD58 | CD58 molecule |
| CHKB | choline kinase beta |
| CLCA2 | chloride channel accessory 2 |
| CPNE7 | copine VII |
| CWF19L1 | CWF19-like 1, cell cycle control (S. pombe) |
| EIF2AK1 | eukaryotic translation initiation factor 2-alpha kinase 1 |
| FBXO38 | F-box protein 38 |
| FNDC3A | fibronectin type III domain containing 3A |
| FNTB | farnesyltransferase, CAAX box, beta |
| GNG13 | guanine nucleotide binding protein (G protein), gamma 13 |
| GP6 | glycoprotein VI (platelet) |
| GPR3 | G protein-coupled receptor 3 |
| GPR4 | G protein-coupled receptor 4 |
| GRM1 | glutamate receptor, metabotropic 1 |
| HLA-F | major histocompatibility complex, class I, F |
| HMGA1 | high mobility group AT-hook 1 |
| HOXB5 | homeobox B5 |
| HSPA12A | heat shock 70kDa protein 12A |
| HTR1B | 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled |
| IL2RA | interleukin 2 receptor, alpha |
| IL33R | interleukin 33 receptor |
| ITFG2 | integrin alpha FG-GAP repeat containing 2 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 |
| KAT8 | K(lysine) acetyltransferase 8 |
| KBTBD11 | kelch repeat and BTB (POZ) domain containing 11 |
| LPCAT3 | lysophosphatidylcholine acyltransferase 3 |
| MAPK1 | mitogen-activated protein kinase 1 |
| MAPK11 | mitogen-activated protein kinase 11 |
| MSH6 | mutS homolog 6 |
| MTA2 | metastasis associated 1 family, member 2 |
| MVP | major vault protein |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase |
| OLFML2A | olfactomedin-like 2A |
| PAX5 | paired box 5 |
| PCNXL2 | pecanex-like 2 (Drosophila) |
| PDX1 | pancreatic and duodenal homeobox 1 |
| PIN1P1 | peptidylprolyl cis/trans isomerase, NIMA-interacting 1 pseudogene 1 |
| PIP5K1A | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha |
| PLLP | plasmolipin |
| POLL | polymerase (DNA directed), lambda |
| POPDC3 | popeye domain containing 3 |
| POT1 | protection of telomeres 1 |
| PPP4R4 | protein phosphatase 4, regulatory subunit 4 |
| PPP5C | protein phosphatase 5, catalytic subunit |
| PTPRJ | protein tyrosine phosphatase, receptor type, J |
| PVR | poliovirus receptor |
| RAD51B | RAD51 paralog B |
| RASL11B | RAS-like, family 11, member B |
| RBMS2 | RNA binding motif, single stranded interacting protein 2 |
| REM1 | RAS (RAD and GEM)-like GTP-binding 1 |
| RPS3A | ribosomal protein S3A |
| RRN3P1 | RNA polymerase I transcription factor homolog (S. cerevisiae) pseudogene 1 |
| SERHL2 | serine hydrolase-like 2 |
| SH3BP2 | SH3-domain binding protein 2 |
| SIGLEC6 | sialic acid binding Ig-like lectin 6 |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 |
| SLC6A8 | solute carrier family 6 (neurotransmitter transporter), member 8 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 |
| SMAD5 | SMAD family member 5 |
| STRA6 | stimulated by retinoic acid 6 |
| SUGP1 | SURP and G patch domain containing 1 |
| SYN3 | synapsin III |
| TAF6L | TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa |
| TBL2 | transducin (beta)-like 2 |
| TBXA2R | thromboxane A2 receptor |
| THBD | thrombomodulin |
| THBS3 | thrombospondin 3 |
| TLE1 | transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) |
| TNS1 | tensin 1 |
| TP53I11 | tumor protein p53 inducible protein 11 |
| TRA2A | transformer 2 alpha homolog (Drosophila) |
| TRIB2 | tribbles pseudokinase 2 |
| TRIM23 | tripartite motif containing 23 |
| TSC22D4 | TSC22 domain family, member 4 |
| TUBA3C | tubulin, alpha 3c |
| USB1 | U6 snRNA biogenesis 1 |
| VPREB3 | pre-B lymphocyte 3 |
| WDFY3 | WD repeat and FYVE domain containing 3 |
| WNK1 | WNK lysine deficient protein kinase 1 |
| ZNF337 | zinc finger protein 337 |
| ZNF528 | zinc finger protein 528 |
| Symbol | Name |
|---|---|
| ACTL8 | actin-like 8 |
| AGPAT3 | 1-acylglycerol-3-phosphate O-acyltransferase 3 |
| AHCTF1 | AT hook containing transcription factor 1 |
| ALOX12P2 | arachidonate 12-lipoxygenase pseudogene 2 |
| APOLD1 | apolipoprotein L domain containing 1 |
| ARHGAP5 | Rho GTPase activating protein 5 |
| ARNTL2 | aryl hydrocarbon receptor nuclear translocator-like 2 |
| BAHCC1 | BAH domain and coiled-coil containing 1 |
| BBS7 | Bardet-Biedl syndrome 7 |
| BCAS1 | breast carcinoma amplified sequence 1 |
| C22ORF29 | chromosome 22 open reading frame 29 |
| CD2AP | CD2-associated protein |
| CENPO | centromere protein O |
| CRYBG3 | beta-gamma crystallin domain containing 3 |
| CTNNBIP1 | catenin, beta interacting protein 1 |
| CUL9 | cullin 9 |
| CXADR | coxsackie virus and adenovirus receptor |
| DGAT1 | diacylglycerol O-acyltransferase 1 |
| F3 | coagulation factor III (thromboplastin, tissue factor) |
| FANCE | Fanconi anemia, complementation group E |
| FBXL2 | F-box and leucine-rich repeat protein 2 |
| FGF23 | fibroblast growth factor 23 |
| GADD45G | growth arrest and DNA-damage-inducible, gamma |
| GINS4 | GINS complex subunit 4 (Sld5 homolog) |
| GLS2 | glutaminase 2 (liver, mitochondrial) |
| GTF2H3 | general transcription factor IIH, polypeptide 3, 34kDa |
| HAUS6 | HAUS augmin-like complex, subunit 6 |
| HDAC4 | histone deacetylase 4 |
| HERC5 | HECT and RLD domain containing E3 ubiquitin protein ligase 5 |
| HIST1H2AL | histone cluster 1, H2al |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 |
| HMOX1 | heme oxygenase 1 |
| IFI6 | interferon, alpha-inducible protein 6 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
| IFT22 | intraflagellar transport 22 |
| IL17RA | interleukin 17 receptor A |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) |
| JUNB | jun B proto-oncogene |
| KCNK12 | potassium channel, two pore domain subfamily K, member 12 |
| KHDRBS3 | KH domain containing, RNA binding, signal transduction associated 3 |
| KLHL26 | kelch-like family member 26 |
| KREMEN2 | kringle containing transmembrane protein 2 |
| LHX1 | LIM homeobox 1 |
| LINC00597 | long intergenic non-protein coding RNA 597 |
| LMNB1 | lamin B1 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 |
| LRFN3 | leucine rich repeat and fibronectin type III domain containing 3 |
| MC1R | melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor) |
| MFAP2 | microfibrillar-associated protein 2 |
| MICAL1 | microtubule associated monooxygenase, calponin and LIM domain containing 1 |
| MUL1 | mitochondrial E3 ubiquitin protein ligase 1 |
| NEUROD4 | neuronal differentiation 4 |
| NFE2L3 | nuclear factor, erythroid 2-like 3 |
| NRTN | neurturin |
| ONECUT2 | one cut homeobox 2 |
| OR2F1 | olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene) |
| PDLIM2 | PDZ and LIM domain 2 (mystique) |
| PEX26 | peroxisomal biogenesis factor 26 |
| PIGQ | phosphatidylinositol glycan anchor biosynthesis, class Q |
| PYCRL | pyrroline-5-carboxylate reductase-like |
| QTRT1 | queuine tRNA-ribosyltransferase 1 |
| RFWD3 | ring finger and WD repeat domain 3 |
| RNF39 | ring finger protein 39 |
| RPL13P5 | ribosomal protein L13 pseudogene 5 |
| RPL23AP32 | ribosomal protein L23a pseudogene 32 |
| RPRD2 | regulation of nuclear pre-mRNA domain containing 2 |
| S100A2 | S100 calcium binding protein A2 |
| SAYSD1 | SAYSVFN motif domain containing 1 |
| SGPP1 | sphingosine-1-phosphate phosphatase 1 |
| SMEK2 | SMEK homolog 2, suppressor of mek1 (Dictyostelium) |
| SND1-IT1 | SND1 intronic transcript 1 |
| SNX16 | sorting nexin 16 |
| SPAG4 | sperm associated antigen 4 |
| SPRY2 | sprouty homolog 2 (Drosophila) |
| SPTLC3 | serine palmitoyltransferase, long chain base subunit 3 |
| STARD5 | StAR-related lipid transfer (START) domain containing 5 |
| SYNC | syncoilin, intermediate filament protein |
| TAF13 | TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa |
| TAOK1 | TAO kinase 1 |
| TIMM50 | translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) |
| TLN1 | talin 1 |
| TMEM45A | transmembrane protein 45A |
| TNRC6B | trinucleotide repeat containing 6B |
| TPCN1 | two pore segment channel 1 |
| TRPM4 | transient receptor potential cation channel, subfamily M, member 4 |
| TSGA10 | testis specific, 10 |
| TTBK2 | tau tubulin kinase 2 |
| TUBA3D | tubulin, alpha 3d |
| UNC119 | unc-119 homolog (C. elegans) |
| UPP1 | uridine phosphorylase 1 |
| XRCC2 | X-ray repair complementing defective repair in Chinese hamster cells 2 |
| YEATS4 | YEATS domain containing 4 |
| ZBTB22 | zinc finger and BTB domain containing 22 |
| ZCWPW1 | zinc finger, CW type with PWWP domain 1 |
| ZNF134 | zinc finger protein 134 |
| ZNF219 | zinc finger protein 219 |
| ZNF329 | zinc finger protein 329 |
| ZNF652 | zinc finger protein 652 |