scoulerine-2891 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the scoulerine-2891 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACRV1 acrosomal vesicle protein 1
ADGRG1 adhesion G protein-coupled receptor G1
ADRA1B adrenoceptor alpha 1B
AMH anti-Mullerian hormone
AP2A2 adaptor-related protein complex 2, alpha 2 subunit
AP5Z1 adaptor-related protein complex 5, zeta 1 subunit
ARHGAP33 Rho GTPase activating protein 33
ARHGEF28 Rho guanine nucleotide exchange factor (GEF) 28
ARL4D ADP-ribosylation factor-like 4D
ARTN artemin
ATP10B ATPase, class V, type 10B
ATP11A ATPase, class VI, type 11A
BAIAP3 BAI1-associated protein 3
BST2 bone marrow stromal cell antigen 2
C11ORF1 chromosome 11 open reading frame 1
C3ORF18 chromosome 3 open reading frame 18
CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit
CACNA1I calcium channel, voltage-dependent, T type, alpha 1I subunit
CD22 CD22 molecule
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
CELP carboxyl ester lipase pseudogene
CEP152 centrosomal protein 152kDa
CFHR2 complement factor H-related 2
CIDEB cell death-inducing DFFA-like effector b
COL5A2 collagen, type V, alpha 2
CTNS cystinosin, lysosomal cystine transporter
CYP4F11 cytochrome P450, family 4, subfamily F, polypeptide 11
DCTN1 dynactin 1
DHX34 DEAH (Asp-Glu-Ala-His) box polypeptide 34
DNASE1 deoxyribonuclease I
DNMBP dynamin binding protein
DOCK10 dedicator of cytokinesis 10
DOCK9 dedicator of cytokinesis 9
DTNB dystrobrevin, beta
DUSP4 dual specificity phosphatase 4
EIF4A1 eukaryotic translation initiation factor 4A1
FBLN1 fibulin 1
FGD1 FYVE, RhoGEF and PH domain containing 1
GIF gastric intrinsic factor (vitamin B synthesis)
GNAT2 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2
GRPR gastrin-releasing peptide receptor
HDAC7 histone deacetylase 7
HIST1H2BL histone cluster 1, H2bl
HIST1H2BN histone cluster 1, H2bn
HOXD11 homeobox D11
HSD17B14 hydroxysteroid (17-beta) dehydrogenase 14
IGLL3P immunoglobulin lambda-like polypeptide 3, pseudogene
IL23A interleukin 23, alpha subunit p19
INO80D INO80 complex subunit D
IRF5 interferon regulatory factor 5
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit)
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
KIAA0319L KIAA0319-like
KIF21B kinesin family member 21B
KLHL25 kelch-like family member 25
L3MBTL1 l(3)mbt-like 1 (Drosophila)
LAMB4 laminin, beta 4
LDLR low density lipoprotein receptor
LY6G6C lymphocyte antigen 6 complex, locus G6C
MED31 mediator complex subunit 31
MEF2C myocyte enhancer factor 2C
METTL7A methyltransferase like 7A
MIER2 mesoderm induction early response 1, family member 2
MINK1 misshapen-like kinase 1
MST1L macrophage stimulating 1-like
MXD3 MAX dimerization protein 3
MXRA8 matrix-remodelling associated 8
MYOF myoferlin
NKX3-2 NK3 homeobox 2
NOVA2 neuro-oncological ventral antigen 2
NUMA1 nuclear mitotic apparatus protein 1
OR3A3 olfactory receptor, family 3, subfamily A, member 3
OSBPL10 oxysterol binding protein-like 10
PDIA2 protein disulfide isomerase family A, member 2
PLXNB3 plexin B3
PRKCA protein kinase C, alpha
PTRF polymerase I and transcript release factor
RAB11B RAB11B, member RAS oncogene family
RAD52 RAD52 homolog (S. cerevisiae)
RASAL2 RAS protein activator like 2
RPL23AP53 ribosomal protein L23a pseudogene 53
RSPH14 radial spoke head 14 homolog (Chlamydomonas)
SAMD4A sterile alpha motif domain containing 4A
SCG2 secretogranin II
SCN8A sodium channel, voltage gated, type VIII alpha subunit
SERHL2 serine hydrolase-like 2
SOX12 SRY (sex determining region Y)-box 12
SPOCK2 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
SSPN sarcospan
SUGP1 SURP and G patch domain containing 1
TLE2 transducin-like enhancer of split 2
TMEM63A transmembrane protein 63A
TRPA1 transient receptor potential cation channel, subfamily A, member 1
VAMP5 vesicle-associated membrane protein 5
WSCD1 WSC domain containing 1
ZYX zyxin

decreased expression

Symbol Name
ACTG2 actin, gamma 2, smooth muscle, enteric
AMPD2 adenosine monophosphate deaminase 2
AMT aminomethyltransferase
ANXA2P3 annexin A2 pseudogene 3
APBB3 amyloid beta (A4) precursor protein-binding, family B, member 3
ARID4A AT rich interactive domain 4A (RBP1-like)
ASB1 ankyrin repeat and SOCS box containing 1
BAG4 BCL2-associated athanogene 4
BCL9 B-cell CLL/lymphoma 9
BMP4 bone morphogenetic protein 4
C1QTNF9B-AS1 C1QTNF9B antisense RNA 1
C5AR2 complement component 5a receptor 2
CAMK4 calcium/calmodulin-dependent protein kinase IV
CAPN5 calpain 5
CARD8 caspase recruitment domain family, member 8
CBR4 carbonyl reductase 4
CBX8 chromobox homolog 8
CIC capicua transcriptional repressor
CIDEC cell death-inducing DFFA-like effector c
CISH cytokine inducible SH2-containing protein
CLDN15 claudin 15
CLDND1 claudin domain containing 1
CXORF56 chromosome X open reading frame 56
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DNALI1 dynein, axonemal, light intermediate chain 1
DUSP13 dual specificity phosphatase 13
DYNC2H1 dynein, cytoplasmic 2, heavy chain 1
ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7
EPB41L5 erythrocyte membrane protein band 4.1 like 5
EXO5 exonuclease 5
FAM188A family with sequence similarity 188, member A
FLRT3 fibronectin leucine rich transmembrane protein 3
FURIN furin (paired basic amino acid cleaving enzyme)
FUT1 fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group)
GPR19 G protein-coupled receptor 19
GSTA4 glutathione S-transferase alpha 4
HIST1H2AJ histone cluster 1, H2aj
HIST1H4E histone cluster 1, H4e
HSPA1L heat shock 70kDa protein 1-like
IFIT5 interferon-induced protein with tetratricopeptide repeats 5
INCENP inner centromere protein antigens 135/155kDa
IRAK4 interleukin-1 receptor-associated kinase 4
IRF2BP1 interferon regulatory factor 2 binding protein 1
KCNMB3 potassium channel subfamily M regulatory beta subunit 3
KIAA0895 KIAA0895
KIFAP3 kinesin-associated protein 3
KLF3 Kruppel-like factor 3 (basic)
KLHL28 kelch-like family member 28
LINC00115 long intergenic non-protein coding RNA 115
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
LYL1 lymphoblastic leukemia associated hematopoiesis regulator 1
MAPK8 mitogen-activated protein kinase 8
MDN1 MDN1, midasin homolog (yeast)
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NPIPB3 nuclear pore complex interacting protein family, member B3
NPY1R neuropeptide Y receptor Y1
NXPE3 neurexophilin and PC-esterase domain family, member 3
PCSK1N proprotein convertase subtilisin/kexin type 1 inhibitor
PELI1 pellino E3 ubiquitin protein ligase 1
PHC3 polyhomeotic homolog 3 (Drosophila)
PIGN phosphatidylinositol glycan anchor biosynthesis, class N
PLEKHO2 pleckstrin homology domain containing, family O member 2
PRKAB2 protein kinase, AMP-activated, beta 2 non-catalytic subunit
R3HCC1L R3H domain and coiled-coil containing 1-like
RFXAP regulatory factor X-associated protein
RIN2 Ras and Rab interactor 2
RPGR retinitis pigmentosa GTPase regulator
SCAF4 SR-related CTD-associated factor 4
SCD5 stearoyl-CoA desaturase 5
SLC46A3 solute carrier family 46, member 3
SP1 Sp1 transcription factor
SRD5A3 steroid 5 alpha-reductase 3
SSR3 signal sequence receptor, gamma (translocon-associated protein gamma)
SYBU syntabulin (syntaxin-interacting)
TAF4B TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa
TMC7 transmembrane channel-like 7
TMEM183A transmembrane protein 183A
TMEM209 transmembrane protein 209
TMEM254 transmembrane protein 254
TNFSF13 tumor necrosis factor (ligand) superfamily, member 13
TRAPPC11 trafficking protein particle complex 11
TRIM21 tripartite motif containing 21
TRIM5 tripartite motif containing 5
USP27X ubiquitin specific peptidase 27, X-linked
VASH2 vasohibin 2
YIPF4 Yip1 domain family, member 4
YY2 YY2 transcription factor
ZBED8 zinc finger, BED-type containing 8
ZBTB22 zinc finger and BTB domain containing 22
ZNF365 zinc finger protein 365
ZNF37BP zinc finger protein 37B, pseudogene
ZNF428 zinc finger protein 428
ZNF552 zinc finger protein 552
ZNF669 zinc finger protein 669
ZNF747 zinc finger protein 747
ZNF862 zinc finger protein 862
ZSCAN9 zinc finger and SCAN domain containing 9