scoulerine-5536 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the scoulerine-5536 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABHD6 abhydrolase domain containing 6
ACTL8 actin-like 8
ADAMTS13 ADAM metallopeptidase with thrombospondin type 1 motif, 13
ADRA1D adrenoceptor alpha 1D
AKAP17A A kinase (PRKA) anchor protein 17A
ALDOB aldolase B, fructose-bisphosphate
ALOX12P2 arachidonate 12-lipoxygenase pseudogene 2
ANK1 ankyrin 1, erythrocytic
ATF6B activating transcription factor 6 beta
ATG13 autophagy related 13
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein)
BIN1 bridging integrator 1
C11ORF63 chromosome 11 open reading frame 63
C1ORF68 chromosome 1 open reading frame 68
CCDC121 coiled-coil domain containing 121
CCL2 chemokine (C-C motif) ligand 2
CCPG1 cell cycle progression 1
CD247 CD247 molecule
CD300A CD300a molecule
CEP68 centrosomal protein 68kDa
CFP complement factor properdin
CHRNA2 cholinergic receptor, nicotinic, alpha 2 (neuronal)
CPED1 cadherin-like and PC-esterase domain containing 1
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
DGCR8 DGCR8 microprocessor complex subunit
DNPEP aspartyl aminopeptidase
DPF1 D4, zinc and double PHD fingers family 1
DRD2 dopamine receptor D2
EFNB3 ephrin-B3
EVPL envoplakin
HECW1 HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1
HFE hemochromatosis
HHAT hedgehog acyltransferase
HOXA7 homeobox A7
HPCA hippocalcin
JADE2 jade family PHD finger 2
KANK1 KN motif and ankyrin repeat domains 1
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KIAA0125 KIAA0125
KLF6 Kruppel-like factor 6
LPAR6 lysophosphatidic acid receptor 6
LRRC23 leucine rich repeat containing 23
MAGEA6 melanoma antigen family A6
MAP4K1 mitogen-activated protein kinase kinase kinase kinase 1
MBD1 methyl-CpG binding domain protein 1
MCOLN1 mucolipin 1
MFAP2 microfibrillar-associated protein 2
MFGE8 milk fat globule-EGF factor 8 protein
MT1F metallothionein 1F
MYCNOS MYCN opposite strand
NCAM1 neural cell adhesion molecule 1
NFYA nuclear transcription factor Y, alpha
NPR3 natriuretic peptide receptor 3
NRN1 neuritin 1
NRSN2 neurensin 2
OSMR oncostatin M receptor
PAX2 paired box 2
PCCA propionyl CoA carboxylase, alpha polypeptide
PHF7 PHD finger protein 7
PRKCH protein kinase C, eta
PRODH2 proline dehydrogenase (oxidase) 2
PWAR5 Prader Willi/Angelman region RNA 5
RAB35 RAB35, member RAS oncogene family
RFPL1S RFPL1 antisense RNA 1
RIMS2 regulating synaptic membrane exocytosis 2
RIMS3 regulating synaptic membrane exocytosis 3
RPL23AP53 ribosomal protein L23a pseudogene 53
RPL7 ribosomal protein L7
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2
SAYSD1 SAYSVFN motif domain containing 1
SBNO2 strawberry notch homolog 2 (Drosophila)
SERPINB13 serpin peptidase inhibitor, clade B (ovalbumin), member 13
SH3BP2 SH3-domain binding protein 2
SIRT3 sirtuin 3
SKAP1 src kinase associated phosphoprotein 1
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7
SLC30A3 solute carrier family 30 (zinc transporter), member 3
SPTBN5 spectrin, beta, non-erythrocytic 5
SRRT serrate, RNA effector molecule
SUGP1 SURP and G patch domain containing 1
TADA3 transcriptional adaptor 3
TAPBP TAP binding protein (tapasin)
TCP10L t-complex 10-like
TEX14 testis expressed 14
TIMP3 TIMP metallopeptidase inhibitor 3
TOX thymocyte selection-associated high mobility group box
TRD T cell receptor delta locus
TRIB2 tribbles pseudokinase 2
UNC93A unc-93 homolog A (C. elegans)
USP22 ubiquitin specific peptidase 22
WNK1 WNK lysine deficient protein kinase 1
WWP2 WW domain containing E3 ubiquitin protein ligase 2
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase
ZFYVE9 zinc finger, FYVE domain containing 9
ZNF771 zinc finger protein 771
ZYX zyxin

decreased expression

Symbol Name
AFF4 AF4/FMR2 family, member 4
AKR1C3 aldo-keto reductase family 1, member C3
ARAF A-Raf proto-oncogene, serine/threonine kinase
BAHCC1 BAH domain and coiled-coil containing 1
BCORL1 BCL6 corepressor-like 1
BIRC7 baculoviral IAP repeat containing 7
C22ORF29 chromosome 22 open reading frame 29
C8ORF60 chromosome 8 open reading frame 60
C9ORF9 chromosome 9 open reading frame 9
CASP8AP2 caspase 8 associated protein 2
CBR4 carbonyl reductase 4
CBX4 chromobox homolog 4
CCDC186 coiled-coil domain containing 186
CENPC centromere protein C
CFAP44 cilia and flagella associated protein 44
CHKB choline kinase beta
CHML choroideremia-like (Rab escort protein 2)
CLCN5 chloride channel, voltage-sensitive 5
CLDN15 claudin 15
CLDND1 claudin domain containing 1
CSNK1E casein kinase 1, epsilon
CUEDC1 CUE domain containing 1
CYP2J2 cytochrome P450, family 2, subfamily J, polypeptide 2
DCAF13 DDB1 and CUL4 associated factor 13
DUSP2 dual specificity phosphatase 2
DYNC2H1 dynein, cytoplasmic 2, heavy chain 1
EFNA3 ephrin-A3
EPB41L5 erythrocyte membrane protein band 4.1 like 5
ERN2 endoplasmic reticulum to nucleus signaling 2
EXOC5 exocyst complex component 5
FAM110B family with sequence similarity 110, member B
FANCC Fanconi anemia, complementation group C
FBXL2 F-box and leucine-rich repeat protein 2
FURIN furin (paired basic amino acid cleaving enzyme)
GCNT1 glucosaminyl (N-acetyl) transferase 1, core 2
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GPATCH2L G patch domain containing 2-like
HIST1H2AI histone cluster 1, H2ai
HIST1H2AJ histone cluster 1, H2aj
HIST1H2AL histone cluster 1, H2al
IRAK4 interleukin-1 receptor-associated kinase 4
KLF11 Kruppel-like factor 11
LAX1 lymphocyte transmembrane adaptor 1
LINC00115 long intergenic non-protein coding RNA 115
LRRC20 leucine rich repeat containing 20
LZTR1 leucine-zipper-like transcription regulator 1
MAGEH1 melanoma antigen family H1
MAP1S microtubule-associated protein 1S
METTL16 methyltransferase like 16
MYL5 myosin, light chain 5, regulatory
NR1H2 nuclear receptor subfamily 1, group H, member 2
NT5DC3 5'-nucleotidase domain containing 3
NUDT6 nudix (nucleoside diphosphate linked moiety X)-type motif 6
OR7E156P olfactory receptor, family 7, subfamily E, member 156 pseudogene
OSGEPL1 O-sialoglycoprotein endopeptidase-like 1
PCSK7 proprotein convertase subtilisin/kexin type 7
PEX26 peroxisomal biogenesis factor 26
PGBD5 piggyBac transposable element derived 5
PGPEP1 pyroglutamyl-peptidase I
PIK3R5 phosphoinositide-3-kinase, regulatory subunit 5
PITX2 paired-like homeodomain 2
PLEKHM2 pleckstrin homology domain containing, family M (with RUN domain) member 2
POTEKP POTE ankyrin domain family, member K, pseudogene
PTK6 protein tyrosine kinase 6
PVRL2 poliovirus receptor-related 2 (herpesvirus entry mediator B)
PVRL3 poliovirus receptor-related 3
RAB23 RAB23, member RAS oncogene family
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
RCOR3 REST corepressor 3
RLN2 relaxin 2
RNF122 ring finger protein 122
RNF43 ring finger protein 43
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SH2B3 SH2B adaptor protein 3
SIK1 salt-inducible kinase 1
SLC12A5 solute carrier family 12 (potassium/chloride transporter), member 5
SLC16A10 solute carrier family 16 (aromatic amino acid transporter), member 10
SLC22A4 solute carrier family 22 (organic cation/zwitterion transporter), member 4
SLC44A1 solute carrier family 44 (choline transporter), member 1
SLMO1 slowmo homolog 1 (Drosophila)
SNHG20 small nucleolar RNA host gene 20
SP140L SP140 nuclear body protein-like
SSBP3 single stranded DNA binding protein 3
TCTN1 tectonic family member 1
TMEM242 transmembrane protein 242
VWA1 von Willebrand factor A domain containing 1
WDR62 WD repeat domain 62
ZBED1 zinc finger, BED-type containing 1
ZNF141 zinc finger protein 141
ZNF211 zinc finger protein 211
ZNF329 zinc finger protein 329
ZNF492 zinc finger protein 492
ZNF573 zinc finger protein 573
ZNF696 zinc finger protein 696
ZNF83 zinc finger protein 83
ZSCAN31 zinc finger and SCAN domain containing 31