scrib Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description scribbled planar cell polarity protein|This gene encodes a protein that was identified as being similar to the Drosophila scribble protein. The mammalian protein is involved in tumor suppression pathways. As a scaffold protein involved in cell polarization processes, this protein binds to many other proteins. The encoded protein binds to papillomavirus E6 protein via its PDZ domain and the C-terminus of E6. Two alternatively spliced transcript variants that encode different protein isoforms have been found for this gene. [provided by RefSeq, Nov 2011] (NCBI Entrez Gene Database, 23513)
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Genes

15 genes co-occuring with the biological term scrib in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
AKT1 v-akt murine thymoma viral oncogene homolog 1
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
DLG1 discs, large homolog 1 (Drosophila)
KRAS Kirsten rat sarcoma viral oncogene homolog
LPP LIM domain containing preferred translocation partner in lipoma
MAGI1 membrane associated guanylate kinase, WW and PDZ domain containing 1
MCC mutated in colorectal cancers
MIR296 microRNA 296
NOS1AP nitric oxide synthase 1 (neuronal) adaptor protein
PHLPP1 PH domain and leucine rich repeat protein phosphatase 1
PUF60 poly-U binding splicing factor 60KDa
SCRIB scribbled planar cell polarity protein
TRIP6 thyroid hormone receptor interactor 6
VANGL1 VANGL planar cell polarity protein 1
VIM vimentin