second-messenger-mediated signaling Gene Set

Dataset GO Biological Process Annotations 2023
Category structural or functional annotations
Type biological process
Description Any intracellular signal transduction in which the signal is passed on within the cell via a second messenger; a small molecule or ion that can be quickly generated or released from intracellular stores, and can diffuse within the cell. Second-messenger signaling includes production or release of the second messenger, and effectors downstream of the second messenger that further transmit the signal within the cell. (Gene Ontology, GO_0019932)
External Link http://amigo.geneontology.org/amigo/term/GO_0019932
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Genes

73 genes participating in the second-messenger-mediated signaling biological process from the curated GO Biological Process Annotations 2023 dataset.

Symbol Name
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AGTR1 angiotensin II receptor, type 1
AGTR2 angiotensin II receptor, type 2
APOE apolipoprotein E
BTK Bruton agammaglobulinemia tyrosine kinase
CAMKK2 calcium/calmodulin-dependent protein kinase kinase 2, beta
CCL3 chemokine (C-C motif) ligand 3
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene)
CCR6 chemokine (C-C motif) receptor 6
CD36 CD36 molecule (thrombospondin receptor)
CHRM3 cholinergic receptor, muscarinic 3
CNKSR2 connector enhancer of kinase suppressor of Ras 2
CXCL8 chemokine (C-X-C motif) ligand 8
CXCR4 chemokine (C-X-C motif) receptor 4
DDAH1 dimethylarginine dimethylaminohydrolase 1
DDAH2 dimethylarginine dimethylaminohydrolase 2
DHX8 DEAH (Asp-Glu-Ala-His) box polypeptide 8
EDN1 endothelin 1
EDN2 endothelin 2
EDN3 endothelin 3
EDNRB endothelin receptor type B
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3
FCGR3A Fc fragment of IgG, low affinity IIIa, receptor (CD16a)
FPR1 formyl peptide receptor 1
FPR2 formyl peptide receptor 2
GPR62 G protein-coupled receptor 62
GUCY1A3 guanylate cyclase 1, soluble, alpha 3
GUCY1B3 guanylate cyclase 1, soluble, beta 3
HTR2B 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
INPP5A inositol polyphosphate-5-phosphatase, 40kDa
KLRG1 killer cell lectin-like receptor subfamily G, member 1
LACRT lacritin
LAT2 linker for activation of T cells family, member 2
LRRK2 leucine-rich repeat kinase 2
MCTP1 multiple C2 domains, transmembrane 1
MCTP2 multiple C2 domains, transmembrane 2
MCU mitochondrial calcium uniporter
NCALD neurocalcin delta
NDNF neuron-derived neurotrophic factor
NEUROD1 neuronal differentiation 1
NMUR1 neuromedin U receptor 1
NMUR2 neuromedin U receptor 2
NOS1 nitric oxide synthase 1 (neuronal)
NOS2 nitric oxide synthase 2, inducible
NOS3 nitric oxide synthase 3 (endothelial cell)
NUDT4 nudix (nucleoside diphosphate linked moiety X)-type motif 4
ORC3 origin recognition complex, subunit 3
P2RX4 purinergic receptor P2X, ligand gated ion channel, 4
P2RY11 purinergic receptor P2Y, G-protein coupled, 11
P2RY12 purinergic receptor P2Y, G-protein coupled, 12
PDPK1 3-phosphoinositide dependent protein kinase 1
PDX1 pancreatic and duodenal homeobox 1
PLA2G4B phospholipase A2, group IVB (cytosolic)
PLCE1 phospholipase C, epsilon 1
PLCG1 phospholipase C, gamma 1
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)
POMC proopiomelanocortin
PPP1R9A protein phosphatase 1, regulatory subunit 9A
PPP1R9B protein phosphatase 1, regulatory subunit 9B
PPP2CA protein phosphatase 2, catalytic subunit, alpha isozyme
PPP2R1A protein phosphatase 2, regulatory subunit A, alpha
PTGDR2 prostaglandin D2 receptor 2
RCAN1 regulator of calcineurin 1
RCAN2 regulator of calcineurin 2
RCAN3 RCAN family member 3
RILPL1 Rab interacting lysosomal protein-like 1
RYR2 ryanodine receptor 2 (cardiac)
SAMD14 sterile alpha motif domain containing 14
SELE selectin E
SPHK1 sphingosine kinase 1
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11
TPCN2 two pore segment channel 2
TRPM4 transient receptor potential cation channel, subfamily M, member 4