| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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196 genes differentially expressed following the securinine-2729 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCB9 | ATP-binding cassette, sub-family B (MDR/TAP), member 9 |
| AIPL1 | aryl hydrocarbon receptor interacting protein-like 1 |
| AJAP1 | adherens junctions associated protein 1 |
| ANGEL2 | angel homolog 2 (Drosophila) |
| ANGPT1 | angiopoietin 1 |
| APOM | apolipoprotein M |
| ARVCF | armadillo repeat gene deleted in velocardiofacial syndrome |
| ATP10A | ATPase, class V, type 10A |
| BAG3 | BCL2-associated athanogene 3 |
| BIN1 | bridging integrator 1 |
| CD34 | CD34 molecule |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) |
| CNNM4 | cyclin and CBS domain divalent metal cation transport mediator 4 |
| COL17A1 | collagen, type XVII, alpha 1 |
| CYP27A1 | cytochrome P450, family 27, subfamily A, polypeptide 1 |
| DBNDD1 | dysbindin (dystrobrevin binding protein 1) domain containing 1 |
| DCTN2 | dynactin 2 (p50) |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 |
| DNAJB4 | DnaJ (Hsp40) homolog, subfamily B, member 4 |
| DNAJC4 | DnaJ (Hsp40) homolog, subfamily C, member 4 |
| DNPH1 | 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 |
| EGR1 | early growth response 1 |
| ELSPBP1 | epididymal sperm binding protein 1 |
| EML3 | echinoderm microtubule associated protein like 3 |
| EPHA5 | EPH receptor A5 |
| F11 | coagulation factor XI |
| FCAR | Fc fragment of IgA receptor |
| GAS8 | growth arrest-specific 8 |
| GCLM | glutamate-cysteine ligase, modifier subunit |
| GNAT2 | guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2 |
| HIST1H4G | histone cluster 1, H4g |
| HMOX1 | heme oxygenase 1 |
| HOMER2 | homer scaffolding protein 2 |
| HPCAL4 | hippocalcin like 4 |
| HSD17B8 | hydroxysteroid (17-beta) dehydrogenase 8 |
| HSPA8 | heat shock 70kDa protein 8 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 |
| HTR2A | 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled |
| IGF1R | insulin-like growth factor 1 receptor |
| IL1RAPL2 | interleukin 1 receptor accessory protein-like 2 |
| IL6ST | interleukin 6 signal transducer |
| INSL5 | insulin-like 5 |
| IRF4 | interferon regulatory factor 4 |
| KANSL1L | KAT8 regulatory NSL complex subunit 1-like |
| KIF24 | kinesin family member 24 |
| KLF6 | Kruppel-like factor 6 |
| KRT2 | keratin 2, type II |
| KRT6B | keratin 6B, type II |
| LAMP1 | lysosomal-associated membrane protein 1 |
| LEPR | leptin receptor |
| LOC100131613 | PRO1454 |
| MAMLD1 | mastermind-like domain containing 1 |
| MAPT | microtubule-associated protein tau |
| ME1 | malic enzyme 1, NADP(+)-dependent, cytosolic |
| MUC3B | mucin 3B, cell surface associated |
| MYH10 | myosin, heavy chain 10, non-muscle |
| NECAB2 | N-terminal EF-hand calcium binding protein 2 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 |
| NRF1 | nuclear respiratory factor 1 |
| NUP214 | nucleoporin 214kDa |
| OR2S2 | olfactory receptor, family 2, subfamily S, member 2 (gene/pseudogene) |
| PAFAH2 | platelet-activating factor acetylhydrolase 2, 40kDa |
| PAX4 | paired box 4 |
| PCDHGA10 | protocadherin gamma subfamily A, 10 |
| PDE4D | phosphodiesterase 4D, cAMP-specific |
| PGD | phosphogluconate dehydrogenase |
| PIR | pirin (iron-binding nuclear protein) |
| PLEK2 | pleckstrin 2 |
| PQLC2 | PQ loop repeat containing 2 |
| PURA | purine-rich element binding protein A |
| RAB11B | RAB11B, member RAS oncogene family |
| REEP2 | receptor accessory protein 2 |
| RGS5 | regulator of G-protein signaling 5 |
| RIT1 | Ras-like without CAAX 1 |
| RPL23AP53 | ribosomal protein L23a pseudogene 53 |
| S100A3 | S100 calcium binding protein A3 |
| SARM1 | sterile alpha and TIR motif containing 1 |
| SERPINA5 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 |
| SLC48A1 | solute carrier family 48 (heme transporter), member 1 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SNPH | syntaphilin |
| SQSTM1 | sequestosome 1 |
| SRD5A2 | steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2) |
| SRSF7 | serine/arginine-rich splicing factor 7 |
| ST3GAL4 | ST3 beta-galactoside alpha-2,3-sialyltransferase 4 |
| STK17A | serine/threonine kinase 17a |
| TAS2R1 | taste receptor, type 2, member 1 |
| TMEM2 | transmembrane protein 2 |
| TMPRSS6 | transmembrane protease, serine 6 |
| TNFSF4 | tumor necrosis factor (ligand) superfamily, member 4 |
| TRD | T cell receptor delta locus |
| TRIM16 | tripartite motif containing 16 |
| TXNRD1 | thioredoxin reductase 1 |
| UBOX5 | U-box domain containing 5 |
| UNKL | unkempt family zinc finger-like |
| ZNF205 | zinc finger protein 205 |
| ZNF407 | zinc finger protein 407 |
| Symbol | Name |
|---|---|
| ABCA5 | ATP-binding cassette, sub-family A (ABC1), member 5 |
| ACP6 | acid phosphatase 6, lysophosphatidic |
| ADGRE2 | adhesion G protein-coupled receptor E2 |
| ADRB2 | adrenoceptor beta 2, surface |
| AEN | apoptosis enhancing nuclease |
| AMT | aminomethyltransferase |
| ARAP3 | ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3 |
| ARHGEF3 | Rho guanine nucleotide exchange factor (GEF) 3 |
| ASIC1 | acid sensing (proton gated) ion channel 1 |
| BACE1 | beta-site APP-cleaving enzyme 1 |
| BAHCC1 | BAH domain and coiled-coil containing 1 |
| BAMBI | BMP and activin membrane-bound inhibitor |
| BPHL | biphenyl hydrolase-like (serine hydrolase) |
| C11ORF21 | chromosome 11 open reading frame 21 |
| C1ORF106 | chromosome 1 open reading frame 106 |
| CCND1 | cyclin D1 |
| CD1D | CD1d molecule |
| CD3EAP | CD3e molecule, epsilon associated protein |
| CD82 | CD82 molecule |
| CEBPE | CCAAT/enhancer binding protein (C/EBP), epsilon |
| CHST2 | carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2 |
| CUL9 | cullin 9 |
| CX3CR1 | chemokine (C-X3-C motif) receptor 1 |
| DENND5B | DENN/MADD domain containing 5B |
| DIXDC1 | DIX domain containing 1 |
| DKK2 | dickkopf WNT signaling pathway inhibitor 2 |
| DZANK1 | double zinc ribbon and ankyrin repeat domains 1 |
| E2F1 | E2F transcription factor 1 |
| ECI2 | enoyl-CoA delta isomerase 2 |
| ENC1 | ectodermal-neural cortex 1 (with BTB domain) |
| ETV4 | ets variant 4 |
| FANCF | Fanconi anemia, complementation group F |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) |
| GPR85 | G protein-coupled receptor 85 |
| GPRC5C | G protein-coupled receptor, class C, group 5, member C |
| GSDMD | gasdermin D |
| HIST1H2AG | histone cluster 1, H2ag |
| HNRNPA3P1 | heterogeneous nuclear ribonucleoprotein A3 pseudogene 1 |
| ICAM2 | intercellular adhesion molecule 2 |
| IPO8 | importin 8 |
| IRF8 | interferon regulatory factor 8 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) |
| JUP | junction plakoglobin |
| KIAA1024 | KIAA1024 |
| KIAA1107 | KIAA1107 |
| KLHL26 | kelch-like family member 26 |
| LHFP | lipoma HMGIC fusion partner |
| MAGEH1 | melanoma antigen family H1 |
| MANSC1 | MANSC domain containing 1 |
| METTL16 | methyltransferase like 16 |
| MT1HL1 | metallothionein 1H-like 1 |
| MX2 | MX dynamin-like GTPase 2 |
| NAG18 | NAG18 mRNA |
| NFE2 | nuclear factor, erythroid 2 |
| NFE2L3 | nuclear factor, erythroid 2-like 3 |
| NRGN | neurogranin (protein kinase C substrate, RC3) |
| NTSR1 | neurotensin receptor 1 (high affinity) |
| PCYOX1 | prenylcysteine oxidase 1 |
| PDZD7 | PDZ domain containing 7 |
| PGP | phosphoglycolate phosphatase |
| PLEKHO1 | pleckstrin homology domain containing, family O member 1 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 |
| PLTP | phospholipid transfer protein |
| PPAN | peter pan homolog (Drosophila) |
| PSMB9 | proteasome (prosome, macropain) subunit, beta type, 9 |
| PTX3 | pentraxin 3, long |
| RGS16 | regulator of G-protein signaling 16 |
| RNF144A | ring finger protein 144A |
| RSAD1 | radical S-adenosyl methionine domain containing 1 |
| SARS2 | seryl-tRNA synthetase 2, mitochondrial |
| SATB1 | SATB homeobox 1 |
| SEMA3G | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3G |
| SH2D4A | SH2 domain containing 4A |
| SIK1 | salt-inducible kinase 1 |
| SLC15A3 | solute carrier family 15 (oligopeptide transporter), member 3 |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 |
| SLC29A3 | solute carrier family 29 (equilibrative nucleoside transporter), member 3 |
| SLC2A9 | solute carrier family 2 (facilitated glucose transporter), member 9 |
| SLITRK5 | SLIT and NTRK-like family, member 5 |
| SMAD7 | SMAD family member 7 |
| SPINT1 | serine peptidase inhibitor, Kunitz type 1 |
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 |
| SULT1B1 | sulfotransferase family, cytosolic, 1B, member 1 |
| TGM5 | transglutaminase 5 |
| THBS4 | thrombospondin 4 |
| TMEM45A | transmembrane protein 45A |
| TNFSF13 | tumor necrosis factor (ligand) superfamily, member 13 |
| TNS3 | tensin 3 |
| TRIM5 | tripartite motif containing 5 |
| TRIM9 | tripartite motif containing 9 |
| TSPAN32 | tetraspanin 32 |
| TSPYL2 | TSPY-like 2 |
| TUBGCP5 | tubulin, gamma complex associated protein 5 |
| WNT10B | wingless-type MMTV integration site family, member 10B |
| ZC4H2 | zinc finger, C4H2 domain containing |
| ZNF74 | zinc finger protein 74 |
| ZNF862 | zinc finger protein 862 |
