| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the securinine-3470 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACTG2 | actin, gamma 2, smooth muscle, enteric |
| AKAP11 | A kinase (PRKA) anchor protein 11 |
| AKAP13 | A kinase (PRKA) anchor protein 13 |
| AKR1C1 | aldo-keto reductase family 1, member C1 |
| AKR1C2 | aldo-keto reductase family 1, member C2 |
| ALDH5A1 | aldehyde dehydrogenase 5 family, member A1 |
| ALMS1 | Alstrom syndrome protein 1 |
| AREG | amphiregulin |
| ARHGDIG | Rho GDP dissociation inhibitor (GDI) gamma |
| ARTN | artemin |
| ATXN7L3B | ataxin 7-like 3B |
| BCL2L11 | BCL2-like 11 (apoptosis facilitator) |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase |
| CBX8 | chromobox homolog 8 |
| CCDC85B | coiled-coil domain containing 85B |
| CD70 | CD70 molecule |
| CDC25A | cell division cycle 25A |
| CDC42EP2 | CDC42 effector protein (Rho GTPase binding) 2 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 |
| CLN8 | ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation) |
| DAPP1 | dual adaptor of phosphotyrosine and 3-phosphoinositides |
| DIO2 | deiodinase, iodothyronine, type II |
| DNAJB12 | DnaJ (Hsp40) homolog, subfamily B, member 12 |
| DNAJB4 | DnaJ (Hsp40) homolog, subfamily B, member 4 |
| DUSP4 | dual specificity phosphatase 4 |
| EGR3 | early growth response 3 |
| EPOR | erythropoietin receptor |
| ERC2-IT1 | ERC2 intronic transcript 1 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 |
| FAM155B | family with sequence similarity 155, member B |
| FAM212B | family with sequence similarity 212, member B |
| FAM46C | family with sequence similarity 46, member C |
| FOSL1 | FOS-like antigen 1 |
| FSTL3 | follistatin-like 3 (secreted glycoprotein) |
| FUT4 | fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific) |
| FZD10 | frizzled class receptor 10 |
| GINS4 | GINS complex subunit 4 (Sld5 homolog) |
| GNE | glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase |
| GNL3L | guanine nucleotide binding protein-like 3 (nucleolar)-like |
| GREB1 | growth regulation by estrogen in breast cancer 1 |
| HIST1H1D | histone cluster 1, H1d |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) |
| HMOX1 | heme oxygenase 1 |
| HSPA1L | heat shock 70kDa protein 1-like |
| IGFBP5 | insulin-like growth factor binding protein 5 |
| IKBKB | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta |
| IL27RA | interleukin 27 receptor, alpha |
| IL6ST | interleukin 6 signal transducer |
| ITGB5 | integrin, beta 5 |
| JAK2 | Janus kinase 2 |
| LDB1 | LIM domain binding 1 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 |
| MED16 | mediator complex subunit 16 |
| MED18 | mediator complex subunit 18 |
| MEFV | Mediterranean fever |
| METTL7A | methyltransferase like 7A |
| MRPL41 | mitochondrial ribosomal protein L41 |
| MYBL1 | v-myb avian myeloblastosis viral oncogene homolog-like 1 |
| MYL10 | myosin, light chain 10, regulatory |
| NCOA2 | nuclear receptor coactivator 2 |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) |
| NFYA | nuclear transcription factor Y, alpha |
| NMT1 | N-myristoyltransferase 1 |
| NPY5R | neuropeptide Y receptor Y5 |
| ONECUT2 | one cut homeobox 2 |
| OSGIN1 | oxidative stress induced growth inhibitor 1 |
| PARD6B | par-6 family cell polarity regulator beta |
| PAX5 | paired box 5 |
| PIP5K1A | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 |
| PMS2P3 | postmeiotic segregation increased 2 pseudogene 3 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) |
| PPIL2 | peptidylprolyl isomerase (cyclophilin)-like 2 |
| PRKCE | protein kinase C, epsilon |
| PSMB2 | proteasome (prosome, macropain) subunit, beta type, 2 |
| PVR | poliovirus receptor |
| RNF2 | ring finger protein 2 |
| RNFT1 | ring finger protein, transmembrane 1 |
| RPL10L | ribosomal protein L10-like |
| SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B |
| SLC23A2 | solute carrier family 23 (ascorbic acid transporter), member 2 |
| SLC24A3 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SOX9 | SRY (sex determining region Y)-box 9 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 |
| ST3GAL2 | ST3 beta-galactoside alpha-2,3-sialyltransferase 2 |
| TMEM120B | transmembrane protein 120B |
| TMEM63A | transmembrane protein 63A |
| TRIM16 | tripartite motif containing 16 |
| UBE3A | ubiquitin protein ligase E3A |
| USP34 | ubiquitin specific peptidase 34 |
| VGF | VGF nerve growth factor inducible |
| XRCC2 | X-ray repair complementing defective repair in Chinese hamster cells 2 |
| YTHDC1 | YTH domain containing 1 |
| ZBTB22 | zinc finger and BTB domain containing 22 |
| ZHX3 | zinc fingers and homeoboxes 3 |
| ZNF117 | zinc finger protein 117 |
| ZNF286A | zinc finger protein 286A |
| ZNF37BP | zinc finger protein 37B, pseudogene |
| ZNF419 | zinc finger protein 419 |
| Symbol | Name |
|---|---|
| ACADSB | acyl-CoA dehydrogenase, short/branched chain |
| ADGRE5 | adhesion G protein-coupled receptor E5 |
| ALDH1A3 | aldehyde dehydrogenase 1 family, member A3 |
| APBB3 | amyloid beta (A4) precursor protein-binding, family B, member 3 |
| ARHGDIB | Rho GDP dissociation inhibitor (GDI) beta |
| ARHGEF16 | Rho guanine nucleotide exchange factor (GEF) 16 |
| ASB9 | ankyrin repeat and SOCS box containing 9 |
| ASPHD1 | aspartate beta-hydroxylase domain containing 1 |
| BAHD1 | bromo adjacent homology domain containing 1 |
| BFSP1 | beaded filament structural protein 1, filensin |
| C11ORF80 | chromosome 11 open reading frame 80 |
| C16ORF45 | chromosome 16 open reading frame 45 |
| C2ORF54 | chromosome 2 open reading frame 54 |
| CAPN15 | calpain 15 |
| CASD1 | CAS1 domain containing 1 |
| CASZ1 | castor zinc finger 1 |
| CCDC85C | coiled-coil domain containing 85C |
| CCNO | cyclin O |
| CDK20 | cyclin-dependent kinase 20 |
| CEP170B | centrosomal protein 170B |
| CFD | complement factor D (adipsin) |
| CLMN | calmin (calponin-like, transmembrane) |
| CRY2 | cryptochrome circadian clock 2 |
| CRYBB2P1 | crystallin, beta B2 pseudogene 1 |
| DNAJB2 | DnaJ (Hsp40) homolog, subfamily B, member 2 |
| DTX4 | deltex 4, E3 ubiquitin ligase |
| DYNC2H1 | dynein, cytoplasmic 2, heavy chain 1 |
| EFNA1 | ephrin-A1 |
| EHHADH | enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase |
| ELOVL4 | ELOVL fatty acid elongase 4 |
| EPHA4 | EPH receptor A4 |
| F8 | coagulation factor VIII, procoagulant component |
| FAM169A | family with sequence similarity 169, member A |
| FOXRED2 | FAD-dependent oxidoreductase domain containing 2 |
| GATA6 | GATA binding protein 6 |
| HDAC4 | histone deacetylase 4 |
| HOXC11 | homeobox C11 |
| HPS6 | Hermansky-Pudlak syndrome 6 |
| HS1BP3 | HCLS1 binding protein 3 |
| HSD17B11 | hydroxysteroid (17-beta) dehydrogenase 11 |
| IFT81 | intraflagellar transport 81 |
| IRF9 | interferon regulatory factor 9 |
| KCNS3 | potassium voltage-gated channel, modifier subfamily S, member 3 |
| KIAA0513 | KIAA0513 |
| KIF13B | kinesin family member 13B |
| LCP1 | lymphocyte cytosolic protein 1 (L-plastin) |
| LRRC8E | leucine rich repeat containing 8 family, member E |
| LYPD3 | LY6/PLAUR domain containing 3 |
| LZTR1 | leucine-zipper-like transcription regulator 1 |
| LZTS3 | leucine zipper, putative tumor suppressor family member 3 |
| MAPK12 | mitogen-activated protein kinase 12 |
| MAST3 | microtubule associated serine/threonine kinase 3 |
| MCOLN3 | mucolipin 3 |
| MRPL52 | mitochondrial ribosomal protein L52 |
| MSMB | microseminoprotein, beta- |
| MUM1 | melanoma associated antigen (mutated) 1 |
| NDRG4 | NDRG family member 4 |
| NKAIN1 | Na+/K+ transporting ATPase interacting 1 |
| NMU | neuromedin U |
| NREP | neuronal regeneration related protein |
| OSGEPL1 | O-sialoglycoprotein endopeptidase-like 1 |
| P2RY2 | purinergic receptor P2Y, G-protein coupled, 2 |
| P2RY6 | pyrimidinergic receptor P2Y, G-protein coupled, 6 |
| PADI2 | peptidyl arginine deiminase, type II |
| PARD6A | par-6 family cell polarity regulator alpha |
| PDP1 | pyruvate dehyrogenase phosphatase catalytic subunit 1 |
| PHC1 | polyhomeotic homolog 1 (Drosophila) |
| PIK3C2B | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta |
| PKIA | protein kinase (cAMP-dependent, catalytic) inhibitor alpha |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) |
| PLCXD1 | phosphatidylinositol-specific phospholipase C, X domain containing 1 |
| PROS1 | protein S (alpha) |
| PTPRU | protein tyrosine phosphatase, receptor type, U |
| RNF123 | ring finger protein 123 |
| SELENBP1 | selenium binding protein 1 |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A |
| SFXN3 | sideroflexin 3 |
| SGCG | sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein) |
| SIDT1 | SID1 transmembrane family, member 1 |
| SKA1 | spindle and kinetochore associated complex subunit 1 |
| SLC26A2 | solute carrier family 26 (anion exchanger), member 2 |
| SLC26A6 | solute carrier family 26 (anion exchanger), member 6 |
| SLC2A10 | solute carrier family 2 (facilitated glucose transporter), member 10 |
| SLC46A3 | solute carrier family 46, member 3 |
| SLC9A1 | solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 |
| SNAPC2 | small nuclear RNA activating complex, polypeptide 2, 45kDa |
| SP1 | Sp1 transcription factor |
| STAG3 | stromal antigen 3 |
| TCEAL1 | transcription elongation factor A (SII)-like 1 |
| TRIM45 | tripartite motif containing 45 |
| TRIM5 | tripartite motif containing 5 |
| TUBA3C | tubulin, alpha 3c |
| XYLT2 | xylosyltransferase II |
| ZKSCAN3 | zinc finger with KRAB and SCAN domains 3 |
| ZNF211 | zinc finger protein 211 |
| ZNF280D | zinc finger protein 280D |
| ZNF324 | zinc finger protein 324 |
| ZNF623 | zinc finger protein 623 |
