| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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199 genes differentially expressed following the securinine-6831 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 |
| AKR1C1 | aldo-keto reductase family 1, member C1 |
| AKR1C2 | aldo-keto reductase family 1, member C2 |
| AKR1C3 | aldo-keto reductase family 1, member C3 |
| APOE | apolipoprotein E |
| AREG | amphiregulin |
| ARHGEF17 | Rho guanine nucleotide exchange factor (GEF) 17 |
| ARTN | artemin |
| BANP | BTG3 associated nuclear protein |
| BAX | BCL2-associated X protein |
| BTN3A1 | butyrophilin, subfamily 3, member A1 |
| CAPN2 | calpain 2, (m/II) large subunit |
| CASP4 | caspase 4, apoptosis-related cysteine peptidase |
| CDK12 | cyclin-dependent kinase 12 |
| CDRT1 | CMT1A duplicated region transcript 1 |
| CEBPD | CCAAT/enhancer binding protein (C/EBP), delta |
| CLDN1 | claudin 1 |
| COL13A1 | collagen, type XIII, alpha 1 |
| CR1 | complement component (3b/4b) receptor 1 (Knops blood group) |
| CREM | cAMP responsive element modulator |
| CSTF2T | cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa, tau variant |
| CTTN | cortactin |
| CUZD1 | CUB and zona pellucida-like domains 1 |
| CYP4F11 | cytochrome P450, family 4, subfamily F, polypeptide 11 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 |
| DDX28 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 28 |
| DIO2 | deiodinase, iodothyronine, type II |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 |
| DNAJB4 | DnaJ (Hsp40) homolog, subfamily B, member 4 |
| DOCK10 | dedicator of cytokinesis 10 |
| DUSP4 | dual specificity phosphatase 4 |
| EGR1 | early growth response 1 |
| EPHA2 | EPH receptor A2 |
| FAS | Fas cell surface death receptor |
| FGF4 | fibroblast growth factor 4 |
| FOSL1 | FOS-like antigen 1 |
| FUS | FUS RNA binding protein |
| FXYD5 | FXYD domain containing ion transport regulator 5 |
| GABARAPL1 | GABA(A) receptor-associated protein like 1 |
| GABPB1 | GA binding protein transcription factor, beta subunit 1 |
| GCLM | glutamate-cysteine ligase, modifier subunit |
| GNRH2 | gonadotropin-releasing hormone 2 |
| GPATCH2L | G patch domain containing 2-like |
| GSTP1 | glutathione S-transferase pi 1 |
| HMOX1 | heme oxygenase 1 |
| HN1L | hematological and neurological expressed 1-like |
| HSPA1A | heat shock 70kDa protein 1A |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') |
| HSPH1 | heat shock 105kDa/110kDa protein 1 |
| IL6R | interleukin 6 receptor |
| KIAA0232 | KIAA0232 |
| KRTAP2-4 | keratin associated protein 2-4 |
| LIN7A | lin-7 homolog A (C. elegans) |
| MAFG | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G |
| MAPK14 | mitogen-activated protein kinase 14 |
| MBTPS2 | membrane-bound transcription factor peptidase, site 2 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase |
| METTL16 | methyltransferase like 16 |
| MIR22HG | MIR22 host gene |
| MMP25 | matrix metallopeptidase 25 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive |
| NFATC1 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 |
| OSGIN1 | oxidative stress induced growth inhibitor 1 |
| PEX26 | peroxisomal biogenesis factor 26 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 |
| PIP5K1A | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 |
| PPP3R1 | protein phosphatase 3, regulatory subunit B, alpha |
| PRKAB2 | protein kinase, AMP-activated, beta 2 non-catalytic subunit |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 |
| RB1 | retinoblastoma 1 |
| RIT1 | Ras-like without CAAX 1 |
| RPL23AP32 | ribosomal protein L23a pseudogene 32 |
| RYR1 | ryanodine receptor 1 (skeletal) |
| SERGEF | secretion regulating guanine nucleotide exchange factor |
| SERPINI1 | serpin peptidase inhibitor, clade I (neuroserpin), member 1 |
| SETD8 | SET domain containing (lysine methyltransferase) 8 |
| SFTPB | surfactant protein B |
| SLC35E2 | solute carrier family 35, member E2 |
| SLC48A1 | solute carrier family 48 (heme transporter), member 1 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SMG6 | SMG6 nonsense mediated mRNA decay factor |
| SNAI2 | snail family zinc finger 2 |
| SNX29P2 | sorting nexin 29 pseudogene 2 |
| SOX9 | SRY (sex determining region Y)-box 9 |
| SRCAP | Snf2-related CREBBP activator protein |
| SRF | serum response factor (c-fos serum response element-binding transcription factor) |
| STK17B | serine/threonine kinase 17b |
| STYK1 | serine/threonine/tyrosine kinase 1 |
| TIMELESS | timeless circadian clock |
| TNKS2 | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 |
| TPMT | thiopurine S-methyltransferase |
| TRD | T cell receptor delta locus |
| TSC22D2 | TSC22 domain family, member 2 |
| TTC38 | tetratricopeptide repeat domain 38 |
| TXNRD1 | thioredoxin reductase 1 |
| VEGFA | vascular endothelial growth factor A |
| WSCD1 | WSC domain containing 1 |
| XYLB | xylulokinase homolog (H. influenzae) |
| Symbol | Name |
|---|---|
| ALKBH4 | alkB, alkylation repair homolog 4 (E. coli) |
| ALPK1 | alpha-kinase 1 |
| ANKRD36B | ankyrin repeat domain 36B |
| ANP32A-IT1 | ANP32A intronic transcript 1 |
| ARMCX1 | armadillo repeat containing, X-linked 1 |
| ARNTL2 | aryl hydrocarbon receptor nuclear translocator-like 2 |
| ATAD5 | ATPase family, AAA domain containing 5 |
| B3GNT1 | |
| BCL11B | B-cell CLL/lymphoma 11B (zinc finger protein) |
| BRINP3 | bone morphogenetic protein/retinoic acid inducible neural-specific 3 |
| C2ORF54 | chromosome 2 open reading frame 54 |
| C4ORF29 | chromosome 4 open reading frame 29 |
| CCDC25 | coiled-coil domain containing 25 |
| CCNO | cyclin O |
| CNNM1 | cyclin and CBS domain divalent metal cation transport mediator 1 |
| CORT | cortistatin |
| CRIP1 | cysteine-rich protein 1 (intestinal) |
| CYP26A1 | cytochrome P450, family 26, subfamily A, polypeptide 1 |
| DGAT1 | diacylglycerol O-acyltransferase 1 |
| DIP2A | DIP2 disco-interacting protein 2 homolog A (Drosophila) |
| DNAJC22 | DnaJ (Hsp40) homolog, subfamily C, member 22 |
| DSCAM | Down syndrome cell adhesion molecule |
| DUSP2 | dual specificity phosphatase 2 |
| EEF2KMT | eukaryotic elongation factor 2 lysine methyltransferase |
| EFNA3 | ephrin-A3 |
| EPN3 | epsin 3 |
| EXTL2 | exostosin-like glycosyltransferase 2 |
| FBXW12 | F-box and WD repeat domain containing 12 |
| FLT4 | fms-related tyrosine kinase 4 |
| FOXI1 | forkhead box I1 |
| GAMT | guanidinoacetate N-methyltransferase |
| GINS4 | GINS complex subunit 4 (Sld5 homolog) |
| GNB1L | guanine nucleotide binding protein (G protein), beta polypeptide 1-like |
| GPR19 | G protein-coupled receptor 19 |
| GTF2H3 | general transcription factor IIH, polypeptide 3, 34kDa |
| GTPBP2 | GTP binding protein 2 |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| H2AFJ | H2A histone family, member J |
| HDAC11 | histone deacetylase 11 |
| ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein |
| IDI2-AS1 | IDI2 antisense RNA 1 |
| IFT140 | intraflagellar transport 140 |
| IFT22 | intraflagellar transport 22 |
| IFT81 | intraflagellar transport 81 |
| INHBB | inhibin, beta B |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) |
| JADE1 | jade family PHD finger 1 |
| JAG2 | jagged 2 |
| KLHL25 | kelch-like family member 25 |
| LHX6 | LIM homeobox 6 |
| LINC00115 | long intergenic non-protein coding RNA 115 |
| LRRC20 | leucine rich repeat containing 20 |
| MC1R | melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor) |
| MEIS1 | Meis homeobox 1 |
| MNS1 | meiosis-specific nuclear structural 1 |
| NCALD | neurocalcin delta |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa |
| PAFAH2 | platelet-activating factor acetylhydrolase 2, 40kDa |
| PAQR3 | progestin and adipoQ receptor family member III |
| PGP | phosphoglycolate phosphatase |
| PHACTR4 | phosphatase and actin regulator 4 |
| PIGZ | phosphatidylinositol glycan anchor biosynthesis, class Z |
| PLEKHB1 | pleckstrin homology domain containing, family B (evectins) member 1 |
| PODXL | podocalyxin-like |
| POLR1B | polymerase (RNA) I polypeptide B, 128kDa |
| POMT2 | protein-O-mannosyltransferase 2 |
| PP14571 | uncharacterized LOC100130449 |
| PRRG2 | proline rich Gla (G-carboxyglutamic acid) 2 |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 |
| RGS19 | regulator of G-protein signaling 19 |
| RIN1 | Ras and Rab interactor 1 |
| RSPH14 | radial spoke head 14 homolog (Chlamydomonas) |
| SEMA4D | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D |
| SIDT1 | SID1 transmembrane family, member 1 |
| SLC16A10 | solute carrier family 16 (aromatic amino acid transporter), member 10 |
| SLC26A6 | solute carrier family 26 (anion exchanger), member 6 |
| SLC2A10 | solute carrier family 2 (facilitated glucose transporter), member 10 |
| SLC9A8 | solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8 |
| SNAPC2 | small nuclear RNA activating complex, polypeptide 2, 45kDa |
| SP1 | Sp1 transcription factor |
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 |
| STARD13 | StAR-related lipid transfer (START) domain containing 13 |
| SUZ12P1 | suppressor of zeste 12 homolog pseudogene 1 |
| TAOK1 | TAO kinase 1 |
| TIMM50 | translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) |
| TMEM121 | transmembrane protein 121 |
| TRIM21 | tripartite motif containing 21 |
| TRMT2B | tRNA methyltransferase 2 homolog B (S. cerevisiae) |
| TRPM4 | transient receptor potential cation channel, subfamily M, member 4 |
| TTBK2 | tau tubulin kinase 2 |
| TXNIP | thioredoxin interacting protein |
| UAP1L1 | UDP-N-acetylglucosamine pyrophosphorylase 1 like 1 |
| WDR19 | WD repeat domain 19 |
| XPNPEP3 | X-prolyl aminopeptidase 3, mitochondrial |
| XRCC2 | X-ray repair complementing defective repair in Chinese hamster cells 2 |
| YEATS2 | YEATS domain containing 2 |
| ZMYM3 | zinc finger, MYM-type 3 |
| ZNF205 | zinc finger protein 205 |
| ZNF652 | zinc finger protein 652 |
| ZNF721 | zinc finger protein 721 |
