selegiline-2465 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the selegiline-2465 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ANG angiogenin, ribonuclease, RNase A family, 5
ANK3 ankyrin 3, node of Ranvier (ankyrin G)
APOC4 apolipoprotein C-IV
ARMC4 armadillo repeat containing 4
ATP12A ATPase, H+/K+ transporting, nongastric, alpha polypeptide
ATP13A2 ATPase type 13A2
B9D1 B9 protein domain 1
BCL2L1 BCL2-like 1
BMP7 bone morphogenetic protein 7
CCDC170 coiled-coil domain containing 170
CCDC57 coiled-coil domain containing 57
CDH10 cadherin 10, type 2 (T2-cadherin)
CELSR2 cadherin, EGF LAG seven-pass G-type receptor 2
CLEC4E C-type lectin domain family 4, member E
CPTP ceramide-1-phosphate transfer protein
CYP4F8 cytochrome P450, family 4, subfamily F, polypeptide 8
DHX34 DEAH (Asp-Glu-Ala-His) box polypeptide 34
DMTN dematin actin binding protein
DRD2 dopamine receptor D2
EPX eosinophil peroxidase
FAM155A family with sequence similarity 155, member A
FLJ11292
FSCN3 fascin actin-bundling protein 3, testicular
GAA glucosidase, alpha; acid
GATA2 GATA binding protein 2
GJD2 gap junction protein, delta 2, 36kDa
GLP1R glucagon-like peptide 1 receptor
GPR75 G protein-coupled receptor 75
GRK5 G protein-coupled receptor kinase 5
GVINP1 GTPase, very large interferon inducible pseudogene 1
HCG4 HLA complex group 4 (non-protein coding)
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
HOXC8 homeobox C8
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
HTR2A 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
IFT54 intraflagellar transport 54
IGHG1 immunoglobulin heavy constant gamma 1 (G1m marker)
IGLV1-44 immunoglobulin lambda variable 1-44
IL9R interleukin 9 receptor
INE1 inactivation escape 1 (non-protein coding)
KCNAB1 potassium channel, voltage gated subfamily A regulatory beta subunit 1
KDM5B lysine (K)-specific demethylase 5B
KIR2DS1 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 1
KLF12 Kruppel-like factor 12
KRT81 keratin 81, type II
KSR1 kinase suppressor of ras 1
L3MBTL1 l(3)mbt-like 1 (Drosophila)
LOXL3 lysyl oxidase-like 3
LRRN3 leucine rich repeat neuronal 3
MAB21L1 mab-21-like 1 (C. elegans)
MAGEH1 melanoma antigen family H1
MAP4 microtubule-associated protein 4
MET MET proto-oncogene, receptor tyrosine kinase
MT3 metallothionein 3
MTAP methylthioadenosine phosphorylase
MTSS1 metastasis suppressor 1
MUC3A mucin 3A, cell surface associated
MYT1 myelin transcription factor 1
NAP1L2 nucleosome assembly protein 1-like 2
NEK1 NIMA-related kinase 1
NPFFR1 neuropeptide FF receptor 1
NR2E3 nuclear receptor subfamily 2, group E, member 3
NTM neurotrimin
PDE4DIP phosphodiesterase 4D interacting protein
PHLDA1 pleckstrin homology-like domain, family A, member 1
PLAT plasminogen activator, tissue
PLSCR4 phospholipid scramblase 4
PLXNA3 plexin A3
POU2F2 POU class 2 homeobox 2
PTCRA pre T-cell antigen receptor alpha
PTGDS prostaglandin D2 synthase 21kDa (brain)
PTGER3 prostaglandin E receptor 3 (subtype EP3)
RAB11B RAB11B, member RAS oncogene family
RAB11FIP3 RAB11 family interacting protein 3 (class II)
RASGRP2 RAS guanyl releasing protein 2 (calcium and DAG-regulated)
RPS3A ribosomal protein S3A
SBNO2 strawberry notch homolog 2 (Drosophila)
SH3PXD2A SH3 and PX domains 2A
SLN sarcolipin
SPAG8 sperm associated antigen 8
SPRR2B small proline-rich protein 2B
SRF serum response factor (c-fos serum response element-binding transcription factor)
ST3GAL4 ST3 beta-galactoside alpha-2,3-sialyltransferase 4
SYDE1 synapse defective 1, Rho GTPase, homolog 1 (C. elegans)
SYT5 synaptotagmin V
TEAD3 TEA domain family member 3
TIAM1 T-cell lymphoma invasion and metastasis 1
TMPRSS15 transmembrane protease, serine 15
TRIM15 tripartite motif containing 15
TRIO trio Rho guanine nucleotide exchange factor
TRPM1 transient receptor potential cation channel, subfamily M, member 1
WDR59 WD repeat domain 59
WIZ widely interspaced zinc finger motifs
WNT16 wingless-type MMTV integration site family, member 16
WNT7A wingless-type MMTV integration site family, member 7A
XPNPEP1 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble
ZC4H2 zinc finger, C4H2 domain containing
ZCCHC4 zinc finger, CCHC domain containing 4

decreased expression

Symbol Name
ACP6 acid phosphatase 6, lysophosphatidic
ADAM15 ADAM metallopeptidase domain 15
ADGRE1 adhesion G protein-coupled receptor E1
AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3
AHR aryl hydrocarbon receptor
APBB1IP amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
ASGR2 asialoglycoprotein receptor 2
BNC2 basonuclin 2
C8ORF44 chromosome 8 open reading frame 44
CARF calcium responsive transcription factor
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CCL20 chemokine (C-C motif) ligand 20
CCNT1 cyclin T1
CD9 CD9 molecule
CDC37L1 cell division cycle 37-like 1
CHM choroideremia (Rab escort protein 1)
CHML choroideremia-like (Rab escort protein 2)
CHMP6 charged multivesicular body protein 6
CHST7 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7
CIR1 corepressor interacting with RBPJ, 1
COL4A3BP collagen, type IV, alpha 3 (Goodpasture antigen) binding protein
CWC25 CWC25 spliceosome-associated protein homolog (S. cerevisiae)
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
EIF5A2 eukaryotic translation initiation factor 5A2
EML4 echinoderm microtubule associated protein like 4
ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7
FLT4 fms-related tyrosine kinase 4
FNBP1L formin binding protein 1-like
FOXD1 forkhead box D1
FOXN2 forkhead box N2
GDPD3 glycerophosphodiester phosphodiesterase domain containing 3
GK3P glycerol kinase 3 pseudogene
GNB1L guanine nucleotide binding protein (G protein), beta polypeptide 1-like
GTF2I general transcription factor IIi
IL3RA interleukin 3 receptor, alpha (low affinity)
INPP5K inositol polyphosphate-5-phosphatase K
KANSL1L KAT8 regulatory NSL complex subunit 1-like
KCTD20 potassium channel tetramerization domain containing 20
LAIR2 leukocyte-associated immunoglobulin-like receptor 2
LINC00339 long intergenic non-protein coding RNA 339
LY6G6C lymphocyte antigen 6 complex, locus G6C
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
MDM4 MDM4, p53 regulator
MINOS1P1 mitochondrial inner membrane organizing system 1 pseudogene 1
MREG melanoregulin
NABP1 nucleic acid binding protein 1
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NFE2L3 nuclear factor, erythroid 2-like 3
NXPE3 neurexophilin and PC-esterase domain family, member 3
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1
PDP1 pyruvate dehyrogenase phosphatase catalytic subunit 1
PMFBP1 polyamine modulated factor 1 binding protein 1
PNOC prepronociceptin
PRDM1 PR domain containing 1, with ZNF domain
PROCR protein C receptor, endothelial
PTPN4 protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte)
PWAR5 Prader Willi/Angelman region RNA 5
RAPGEFL1 Rap guanine nucleotide exchange factor (GEF)-like 1
RBBP5 retinoblastoma binding protein 5
REC8 REC8 meiotic recombination protein
REEP1 receptor accessory protein 1
RGS13 regulator of G-protein signaling 13
RNASEL ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)
RNF126P1 ring finger protein 126 pseudogene 1
RSPH14 radial spoke head 14 homolog (Chlamydomonas)
SERPINI2 serpin peptidase inhibitor, clade I (pancpin), member 2
SETD8 SET domain containing (lysine methyltransferase) 8
SGPP1 sphingosine-1-phosphate phosphatase 1
SIGLEC15 sialic acid binding Ig-like lectin 15
SLC16A7 solute carrier family 16 (monocarboxylate transporter), member 7
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SLC35F6 solute carrier family 35, member F6
SLC7A2 solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
SNX15 sorting nexin 15
SPIN1 spindlin 1
ST8SIA4 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4
STX11 syntaxin 11
SYNC syncoilin, intermediate filament protein
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TESK1 testis-specific kinase 1
TLR4 toll-like receptor 4
TRIM25 tripartite motif containing 25
TRPS1 trichorhinophalangeal syndrome I
TSC22D4 TSC22 domain family, member 4
UAP1L1 UDP-N-acetylglucosamine pyrophosphorylase 1 like 1
UBE2NL ubiquitin-conjugating enzyme E2N-like (gene/pseudogene)
UGGT1 UDP-glucose glycoprotein glucosyltransferase 1
UNC93B1 unc-93 homolog B1 (C. elegans)
URGCP upregulator of cell proliferation
WDR76 WD repeat domain 76
WDR91 WD repeat domain 91
ZAK sterile alpha motif and leucine zipper containing kinase AZK
ZBTB39 zinc finger and BTB domain containing 39
ZNF10 zinc finger protein 10
ZNF124 zinc finger protein 124
ZNF155 zinc finger protein 155
ZNF37BP zinc finger protein 37B, pseudogene
ZNF480 zinc finger protein 480