| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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190 genes differentially expressed following the selegiline-2826 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AAK1 | AP2 associated kinase 1 |
| ADD3 | adducin 3 (gamma) |
| AGO4 | argonaute RISC catalytic component 4 |
| AMN | amnion associated transmembrane protein |
| ARHGAP33 | Rho GTPase activating protein 33 |
| ARTN | artemin |
| ATP8B2 | ATPase, aminophospholipid transporter, class I, type 8B, member 2 |
| BHLHE40 | basic helix-loop-helix family, member e40 |
| C10ORF95 | chromosome 10 open reading frame 95 |
| C9ORF9 | chromosome 9 open reading frame 9 |
| CCBL1 | cysteine conjugate-beta lyase, cytoplasmic |
| CCDC132 | coiled-coil domain containing 132 |
| CCDC85C | coiled-coil domain containing 85C |
| COPZ2 | coatomer protein complex, subunit zeta 2 |
| CRISP1 | cysteine-rich secretory protein 1 |
| CTNND2 | catenin (cadherin-associated protein), delta 2 |
| DGCR9 | DiGeorge syndrome critical region gene 9 (non-protein coding) |
| DNAJA4 | DnaJ (Hsp40) homolog, subfamily A, member 4 |
| DRD2 | dopamine receptor D2 |
| DUSP9 | dual specificity phosphatase 9 |
| EIF4EBP2 | eukaryotic translation initiation factor 4E binding protein 2 |
| EMID1 | EMI domain containing 1 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 |
| EXOG | endo/exonuclease (5'-3'), endonuclease G-like |
| FGD1 | FYVE, RhoGEF and PH domain containing 1 |
| FOXN3 | forkhead box N3 |
| FRMD4A | FERM domain containing 4A |
| GADD45G | growth arrest and DNA-damage-inducible, gamma |
| GLRA1 | glycine receptor, alpha 1 |
| GMPR | guanosine monophosphate reductase |
| GRIP2 | glutamate receptor interacting protein 2 |
| GRK5 | G protein-coupled receptor kinase 5 |
| HOXC4 | homeobox C4 |
| HPS1 | Hermansky-Pudlak syndrome 1 |
| IFT27 | intraflagellar transport 27 |
| IPO5 | importin 5 |
| ITGA10 | integrin, alpha 10 |
| KDM8 | lysine (K)-specific demethylase 8 |
| KLHL25 | kelch-like family member 25 |
| LAMC2 | laminin, gamma 2 |
| LINC01587 | long intergenic non-protein coding RNA 1587 |
| LMOD1 | leiomodin 1 (smooth muscle) |
| LRRC8B | leucine rich repeat containing 8 family, member B |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 |
| LYST | lysosomal trafficking regulator |
| MAOB | monoamine oxidase B |
| MAP1S | microtubule-associated protein 1S |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase |
| MICAL1 | microtubule associated monooxygenase, calponin and LIM domain containing 1 |
| MMP24 | matrix metallopeptidase 24 (membrane-inserted) |
| MMP25 | matrix metallopeptidase 25 |
| MTCP1 | mature T-cell proliferation 1 |
| MTERF4 | mitochondrial transcription termination factor 4 |
| MTHFR | methylenetetrahydrofolate reductase (NAD(P)H) |
| MYL4 | myosin, light chain 4, alkali; atrial, embryonic |
| NCALD | neurocalcin delta |
| NDRG2 | NDRG family member 2 |
| NEU3 | sialidase 3 (membrane sialidase) |
| NFKBIB | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta |
| OPLAH | 5-oxoprolinase (ATP-hydrolysing) |
| PICK1 | protein interacting with PRKCA 1 |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) |
| PLXNC1 | plexin C1 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) |
| PRB1 | proline-rich protein BstNI subfamily 1 |
| PSG11 | pregnancy specific beta-1-glycoprotein 11 |
| PSG6 | pregnancy specific beta-1-glycoprotein 6 |
| PSMB9 | proteasome (prosome, macropain) subunit, beta type, 9 |
| PVR | poliovirus receptor |
| QPCTL | glutaminyl-peptide cyclotransferase-like |
| RASA3 | RAS p21 protein activator 3 |
| RHBDD3 | rhomboid domain containing 3 |
| RPS3A | ribosomal protein S3A |
| SCARA3 | scavenger receptor class A, member 3 |
| SFTPB | surfactant protein B |
| SH3BP2 | SH3-domain binding protein 2 |
| SLC1A4 | solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 |
| SLC7A8 | solute carrier family 7 (amino acid transporter light chain, L system), member 8 |
| SLC9A1 | solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 |
| SORBS1 | sorbin and SH3 domain containing 1 |
| SPON1 | spondin 1, extracellular matrix protein |
| STRA6 | stimulated by retinoic acid 6 |
| SYNDIG1 | synapse differentiation inducing 1 |
| TAGLN3 | transgelin 3 |
| TAOK2 | TAO kinase 2 |
| TAT | tyrosine aminotransferase |
| TBX2 | T-box 2 |
| TCP10 | t-complex 10 |
| TMEM53 | transmembrane protein 53 |
| TNC | tenascin C |
| TRD | T cell receptor delta locus |
| TRIM21 | tripartite motif containing 21 |
| YPEL1 | yippee-like 1 (Drosophila) |
| ZBTB7A | zinc finger and BTB domain containing 7A |
| ZFP64 | ZFP64 zinc finger protein |
| Symbol | Name |
|---|---|
| ABHD3 | abhydrolase domain containing 3 |
| ARHGDIB | Rho GDP dissociation inhibitor (GDI) beta |
| ATAD3A | ATPase family, AAA domain containing 3A |
| BCORL1 | BCL6 corepressor-like 1 |
| BPGM | 2,3-bisphosphoglycerate mutase |
| C1GALT1 | core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 |
| CALCOCO1 | calcium binding and coiled-coil domain 1 |
| CAPN15 | calpain 15 |
| CBX4 | chromobox homolog 4 |
| CHML | choroideremia-like (Rab escort protein 2) |
| CORT | cortistatin |
| CTC1 | CTS telomere maintenance complex component 1 |
| CTNNBIP1 | catenin, beta interacting protein 1 |
| DARS2 | aspartyl-tRNA synthetase 2, mitochondrial |
| DDX31 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 31 |
| DGAT1 | diacylglycerol O-acyltransferase 1 |
| DLEU2 | deleted in lymphocytic leukemia 2 (non-protein coding) |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 |
| EHHADH | enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase |
| EHMT1 | euchromatic histone-lysine N-methyltransferase 1 |
| EPHA2 | EPH receptor A2 |
| ERCC4 | excision repair cross-complementation group 4 |
| FAM179B | family with sequence similarity 179, member B |
| FAM198B | family with sequence similarity 198, member B |
| FCF1 | FCF1 rRNA-processing protein |
| FKBP14 | FK506 binding protein 14, 22 kDa |
| FRS2 | fibroblast growth factor receptor substrate 2 |
| FUT4 | fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific) |
| GAREM | GRB2 associated, regulator of MAPK1 |
| GCHFR | GTP cyclohydrolase I feedback regulator |
| GDAP1 | ganglioside induced differentiation associated protein 1 |
| GLS2 | glutaminase 2 (liver, mitochondrial) |
| HIRA | histone cell cycle regulator |
| ISOC1 | isochorismatase domain containing 1 |
| LCP1 | lymphocyte cytosolic protein 1 (L-plastin) |
| LEMD3 | LEM domain containing 3 |
| LIG4 | ligase IV, DNA, ATP-dependent |
| LINC00115 | long intergenic non-protein coding RNA 115 |
| LINS | lines homolog (Drosophila) |
| LRP5 | low density lipoprotein receptor-related protein 5 |
| LZTS3 | leucine zipper, putative tumor suppressor family member 3 |
| MAFB | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B |
| MAGEF1 | melanoma antigen family F1 |
| MATK | megakaryocyte-associated tyrosine kinase |
| MICAL3 | microtubule associated monooxygenase, calponin and LIM domain containing 3 |
| MTMR6 | myotubularin related protein 6 |
| NABP2 | nucleic acid binding protein 2 |
| NCS1 | neuronal calcium sensor 1 |
| NDST2 | N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2 |
| NEK11 | NIMA-related kinase 11 |
| NRBF2 | nuclear receptor binding factor 2 |
| NRGN | neurogranin (protein kinase C substrate, RC3) |
| ORAI3 | ORAI calcium release-activated calcium modulator 3 |
| OXR1 | oxidation resistance 1 |
| PGPEP1 | pyroglutamyl-peptidase I |
| PHC1 | polyhomeotic homolog 1 (Drosophila) |
| PHEX | phosphate regulating endopeptidase homolog, X-linked |
| PILRB | paired immunoglobin-like type 2 receptor beta |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 |
| PODXL2 | podocalyxin-like 2 |
| POLH | polymerase (DNA directed), eta |
| PRKAB2 | protein kinase, AMP-activated, beta 2 non-catalytic subunit |
| PRPH | peripherin |
| PTK6 | protein tyrosine kinase 6 |
| PTPRE | protein tyrosine phosphatase, receptor type, E |
| PYCRL | pyrroline-5-carboxylate reductase-like |
| R3HCC1L | R3H domain and coiled-coil containing 1-like |
| RLN2 | relaxin 2 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase |
| RPGR | retinitis pigmentosa GTPase regulator |
| RSF1 | remodeling and spacing factor 1 |
| SETD6 | SET domain containing 6 |
| SLC12A8 | solute carrier family 12, member 8 |
| SMEK2 | SMEK homolog 2, suppressor of mek1 (Dictyostelium) |
| SP1 | Sp1 transcription factor |
| TAGLN | transgelin |
| TARP | TCR gamma alternate reading frame protein |
| TBX19 | T-box 19 |
| TCEAL1 | transcription elongation factor A (SII)-like 1 |
| TMA16 | translation machinery associated 16 homolog (S. cerevisiae) |
| TMEM104 | transmembrane protein 104 |
| TMEM132A | transmembrane protein 132A |
| TPST2 | tyrosylprotein sulfotransferase 2 |
| TRAF6 | TNF receptor-associated factor 6, E3 ubiquitin protein ligase |
| TSPYL2 | TSPY-like 2 |
| TTC33 | tetratricopeptide repeat domain 33 |
| TUBG2 | tubulin, gamma 2 |
| UEVLD | UEV and lactate/malate dehyrogenase domains |
| UGGT2 | UDP-glucose glycoprotein glucosyltransferase 2 |
| VPS54 | vacuolar protein sorting 54 homolog (S. cerevisiae) |
| WWC2 | WW and C2 domain containing 2 |
| XRCC3 | X-ray repair complementing defective repair in Chinese hamster cells 3 |
| ZBTB48 | zinc finger and BTB domain containing 48 |
| ZNF280D | zinc finger protein 280D |
| ZNF573 | zinc finger protein 573 |