semaphorin-plexin signaling pathway Gene Set

Dataset GO Biological Process Annotations 2025
Category structural or functional annotations
Type biological process
Description A series of molecular signals generated as a consequence of a semaphorin receptor (composed of a plexin and a neurophilin) binding to a semaphorin ligand. (Gene Ontology, GO_0071526)
External Link http://amigo.geneontology.org/amigo/term/GO:0071526
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Genes

40 genes participating in the semaphorin-plexin signaling pathway biological process from the curated GO Biological Process Annotations 2025 dataset.

Symbol Name
ARHGDIA Rho GDP dissociation inhibitor (GDI) alpha
ERBB2 erb-b2 receptor tyrosine kinase 2
FARP2 FERM, RhoGEF and pleckstrin domain protein 2
FLNA filamin A, alpha
NRP1 neuropilin 1
NRP2 neuropilin 2
PLXNA1 plexin A1
PLXNA2 plexin A2
PLXNA3 plexin A3
PLXNA4 plexin A4
PLXNB1 plexin B1
PLXNB2 plexin B2
PLXNB3 plexin B3
PLXNC1 plexin C1
PLXND1 plexin D1
RHOA ras homolog family member A
RNASE1 ribonuclease, RNase A family, 1 (pancreatic)
SEMA3A sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
SEMA3B sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
SEMA3D sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D
SEMA3E sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E
SEMA3F sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
SEMA3G sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3G
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
SEMA4B sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B
SEMA4C sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SEMA4F sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4F
SEMA4G sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G
SEMA5A sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A
SEMA5B sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5B
SEMA6A sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
SEMA6B sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B
SEMA6C sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6C
SEMA6D sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D
SEMA7A semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group)
SH3BP1 SH3-domain binding protein 1
SLTM SAFB-like, transcription modulator
TYROBP TYRO protein tyrosine kinase binding protein