| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the semustine-7487 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACVR1B | activin A receptor, type IB |
| ADAM22 | ADAM metallopeptidase domain 22 |
| AIPL1 | aryl hydrocarbon receptor interacting protein-like 1 |
| AK1 | adenylate kinase 1 |
| AKAP4 | A kinase (PRKA) anchor protein 4 |
| AKR1B1 | aldo-keto reductase family 1, member B1 (aldose reductase) |
| AKR1C1 | aldo-keto reductase family 1, member C1 |
| AKR1C2 | aldo-keto reductase family 1, member C2 |
| AKR1C3 | aldo-keto reductase family 1, member C3 |
| ARNT | aryl hydrocarbon receptor nuclear translocator |
| BTBD7 | BTB (POZ) domain containing 7 |
| BTN2A2 | butyrophilin, subfamily 2, member A2 |
| CACNG1 | calcium channel, voltage-dependent, gamma subunit 1 |
| CD200 | CD200 molecule |
| CD53 | CD53 molecule |
| COL13A1 | collagen, type XIII, alpha 1 |
| CPA2 | carboxypeptidase A2 (pancreatic) |
| CTSF | cathepsin F |
| CYP2C9 | cytochrome P450, family 2, subfamily C, polypeptide 9 |
| DIO2 | deiodinase, iodothyronine, type II |
| DNASE1 | deoxyribonuclease I |
| EGR1 | early growth response 1 |
| EHMT1 | euchromatic histone-lysine N-methyltransferase 1 |
| EPHA2 | EPH receptor A2 |
| EPHA3 | EPH receptor A3 |
| EZH1 | enhancer of zeste 1 polycomb repressive complex 2 subunit |
| FAM120C | family with sequence similarity 120C |
| FEM1B | fem-1 homolog b (C. elegans) |
| FLOT1 | flotillin 1 |
| FNDC3A | fibronectin type III domain containing 3A |
| FNTB | farnesyltransferase, CAAX box, beta |
| FOSL1 | FOS-like antigen 1 |
| GADD45G | growth arrest and DNA-damage-inducible, gamma |
| GCLM | glutamate-cysteine ligase, modifier subunit |
| GFI1 | growth factor independent 1 transcription repressor |
| GPR135 | G protein-coupled receptor 135 |
| GPR176 | G protein-coupled receptor 176 |
| GRB10 | growth factor receptor-bound protein 10 |
| HFE | hemochromatosis |
| HMOX1 | heme oxygenase 1 |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') |
| ICOSLG | inducible T-cell co-stimulator ligand |
| IGLL3P | immunoglobulin lambda-like polypeptide 3, pseudogene |
| INPP4A | inositol polyphosphate-4-phosphatase, type I, 107kDa |
| JUN | jun proto-oncogene |
| KAZALD1 | Kazal-type serine peptidase inhibitor domain 1 |
| KRT24 | keratin 24, type I |
| LOC390998 | ribosomal protein L10 pseudogene |
| MAFG | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G |
| MCAM | melanoma cell adhesion molecule |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase |
| MEF2D | myocyte enhancer factor 2D |
| MLXIPL | MLX interacting protein-like |
| NECAB2 | N-terminal EF-hand calcium binding protein 2 |
| NFKBIB | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta |
| NPIPB3 | nuclear pore complex interacting protein family, member B3 |
| OGFR | opioid growth factor receptor |
| OSGIN1 | oxidative stress induced growth inhibitor 1 |
| PAX8 | paired box 8 |
| PCLO | piccolo presynaptic cytomatrix protein |
| PEX16 | peroxisomal biogenesis factor 16 |
| PIDD1 | p53-induced death domain protein 1 |
| PLEKHO2 | pleckstrin homology domain containing, family O member 2 |
| POU2F2 | POU class 2 homeobox 2 |
| PPP2CB | protein phosphatase 2, catalytic subunit, beta isozyme |
| PPP5C | protein phosphatase 5, catalytic subunit |
| PRKAR2A | protein kinase, cAMP-dependent, regulatory, type II, alpha |
| PSD4 | pleckstrin and Sec7 domain containing 4 |
| PTGDS | prostaglandin D2 synthase 21kDa (brain) |
| PTGS1 | prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) |
| RANBP3 | RAN binding protein 3 |
| RASAL1 | RAS protein activator like 1 (GAP1 like) |
| RBBP9 | retinoblastoma binding protein 9 |
| RBM12B | RNA binding motif protein 12B |
| SATB1 | SATB homeobox 1 |
| SETD8 | SET domain containing (lysine methyltransferase) 8 |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 |
| SLC39A9 | solute carrier family 39, member 9 |
| SLC48A1 | solute carrier family 48 (heme transporter), member 1 |
| SLC6A8 | solute carrier family 6 (neurotransmitter transporter), member 8 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SLC9A5 | solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5 |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 |
| SRRT | serrate, RNA effector molecule |
| STK17A | serine/threonine kinase 17a |
| STMN1 | stathmin 1 |
| TAOK2 | TAO kinase 2 |
| TCEB3B | transcription elongation factor B polypeptide 3B (elongin A2) |
| TNFRSF11A | tumor necrosis factor receptor superfamily, member 11a, NFKB activator |
| TRIM16 | tripartite motif containing 16 |
| TRIM23 | tripartite motif containing 23 |
| TRPC1 | transient receptor potential cation channel, subfamily C, member 1 |
| TXNRD1 | thioredoxin reductase 1 |
| VIM | vimentin |
| YPEL1 | yippee-like 1 (Drosophila) |
| ZFP36L1 | ZFP36 ring finger protein-like 1 |
| ZNF532 | zinc finger protein 532 |
| ZNF783 | zinc finger family member 783 |
| Symbol | Name |
|---|---|
| A2M | alpha-2-macroglobulin |
| ABCC4 | ATP-binding cassette, sub-family C (CFTR/MRP), member 4 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 |
| ACADS | acyl-CoA dehydrogenase, C-2 to C-3 short chain |
| ACADSB | acyl-CoA dehydrogenase, short/branched chain |
| ADGRB1 | adhesion G protein-coupled receptor B1 |
| AP3B2 | adaptor-related protein complex 3, beta 2 subunit |
| ARC | activity-regulated cytoskeleton-associated protein |
| ARHGEF17 | Rho guanine nucleotide exchange factor (GEF) 17 |
| B3GNT3 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3 |
| BAG4 | BCL2-associated athanogene 4 |
| BARX2 | BARX homeobox 2 |
| BEX4 | brain expressed, X-linked 4 |
| C10ORF95 | chromosome 10 open reading frame 95 |
| C2ORF54 | chromosome 2 open reading frame 54 |
| CACNA2D2 | calcium channel, voltage-dependent, alpha 2/delta subunit 2 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID |
| CCP110 | centriolar coiled coil protein 110kDa |
| CD48 | CD48 molecule |
| CD82 | CD82 molecule |
| CERS4 | ceramide synthase 4 |
| CNTN5 | contactin 5 |
| CST6 | cystatin E/M |
| CYP4F2 | cytochrome P450, family 4, subfamily F, polypeptide 2 |
| DDX58 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 |
| ENTPD3 | ectonucleoside triphosphate diphosphohydrolase 3 |
| ETNK2 | ethanolamine kinase 2 |
| FAM110B | family with sequence similarity 110, member B |
| FZD2 | frizzled class receptor 2 |
| GBP2 | guanylate binding protein 2, interferon-inducible |
| GJA8 | gap junction protein, alpha 8, 50kDa |
| GLS2 | glutaminase 2 (liver, mitochondrial) |
| GPR87 | G protein-coupled receptor 87 |
| GSTCD | glutathione S-transferase, C-terminal domain containing |
| GSTP1 | glutathione S-transferase pi 1 |
| GTF2I | general transcription factor IIi |
| HDAC7 | histone deacetylase 7 |
| HEXA-AS1 | HEXA antisense RNA 1 |
| HEY2 | hes-related family bHLH transcription factor with YRPW motif 2 |
| HIST1H2BM | histone cluster 1, H2bm |
| HIST1H3B | histone cluster 1, H3b |
| HOXA3 | homeobox A3 |
| HOXC6 | homeobox C6 |
| IL4R | interleukin 4 receptor |
| INO80D | INO80 complex subunit D |
| ITPKB | inositol-trisphosphate 3-kinase B |
| KCNA5 | potassium channel, voltage gated shaker related subfamily A, member 5 |
| KIT | v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog |
| KLF13 | Kruppel-like factor 13 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) |
| KRT15 | keratin 15, type I |
| LENEP | lens epithelial protein |
| LIG4 | ligase IV, DNA, ATP-dependent |
| LIN7A | lin-7 homolog A (C. elegans) |
| LONRF3 | LON peptidase N-terminal domain and ring finger 3 |
| LRP2 | low density lipoprotein receptor-related protein 2 |
| MAK | male germ cell-associated kinase |
| MAP4K2 | mitogen-activated protein kinase kinase kinase kinase 2 |
| MEGF8 | multiple EGF-like-domains 8 |
| MFSD6 | major facilitator superfamily domain containing 6 |
| MGC2889 | uncharacterized protein MGC2889 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 |
| NOD1 | nucleotide-binding oligomerization domain containing 1 |
| NOS1AP | nitric oxide synthase 1 (neuronal) adaptor protein |
| NPHS1 | nephrosis 1, congenital, Finnish type (nephrin) |
| NRDE2 | NRDE-2, necessary for RNA interference, domain containing |
| NSUN6 | NOP2/Sun domain family, member 6 |
| ONECUT2 | one cut homeobox 2 |
| PAIP2B | poly(A) binding protein interacting protein 2B |
| PAK3 | p21 protein (Cdc42/Rac)-activated kinase 3 |
| PCDHA5 | protocadherin alpha 5 |
| PCDHA9 | protocadherin alpha 9 |
| PLA2G4C | phospholipase A2, group IVC (cytosolic, calcium-independent) |
| PLCD1 | phospholipase C, delta 1 |
| PTGER2 | prostaglandin E receptor 2 (subtype EP2), 53kDa |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 |
| QSER1 | glutamine and serine rich 1 |
| RASIP1 | Ras interacting protein 1 |
| RLN1 | relaxin 1 |
| RNF122 | ring finger protein 122 |
| SLC22A14 | solute carrier family 22, member 14 |
| SLC25A21 | solute carrier family 25 (mitochondrial oxoadipate carrier), member 21 |
| STXBP5L | syntaxin binding protein 5-like |
| SYNPO | synaptopodin |
| TBC1D2 | TBC1 domain family, member 2 |
| TESC | tescalcin |
| TMEM121 | transmembrane protein 121 |
| TMEM45A | transmembrane protein 45A |
| TMPRSS4 | transmembrane protease, serine 4 |
| TUBB1 | tubulin, beta 1 class VI |
| UCN | urocortin |
| UNC119 | unc-119 homolog (C. elegans) |
| VAX2 | ventral anterior homeobox 2 |
| VEGFC | vascular endothelial growth factor C |
| WWC2 | WW and C2 domain containing 2 |
| ZNF358 | zinc finger protein 358 |
| ZNF492 | zinc finger protein 492 |
| ZNF76 | zinc finger protein 76 |
