| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
| Downloads & Tools |
197 genes differentially expressed following the semustine-7492 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABHD4 | abhydrolase domain containing 4 |
| ADCK2 | aarF domain containing kinase 2 |
| AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) |
| AKR1C1 | aldo-keto reductase family 1, member C1 |
| AKR1C2 | aldo-keto reductase family 1, member C2 |
| AKR1C3 | aldo-keto reductase family 1, member C3 |
| AMIGO2 | adhesion molecule with Ig-like domain 2 |
| ANXA10 | annexin A10 |
| APH1B | APH1B gamma secretase subunit |
| ARG2 | arginase 2 |
| ARNTL | aryl hydrocarbon receptor nuclear translocator-like |
| B4GALNT1 | beta-1,4-N-acetyl-galactosaminyl transferase 1 |
| BCKDHB | branched chain keto acid dehydrogenase E1, beta polypeptide |
| C1ORF56 | chromosome 1 open reading frame 56 |
| C9ORF156 | chromosome 9 open reading frame 156 |
| CA9 | carbonic anhydrase IX |
| CACFD1 | calcium channel flower domain containing 1 |
| CBS | cystathionine-beta-synthase |
| CDIP1 | cell death-inducing p53 target 1 |
| CDKN1C | cyclin-dependent kinase inhibitor 1C (p57, Kip2) |
| CEBPA | CCAAT/enhancer binding protein (C/EBP), alpha |
| CENPO | centromere protein O |
| CGREF1 | cell growth regulator with EF-hand domain 1 |
| CLU | clusterin |
| CNR2 | cannabinoid receptor 2 (macrophage) |
| CSGALNACT2 | chondroitin sulfate N-acetylgalactosaminyltransferase 2 |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DHRS9 | dehydrogenase/reductase (SDR family) member 9 |
| DMTN | dematin actin binding protein |
| DNAJB12 | DnaJ (Hsp40) homolog, subfamily B, member 12 |
| DNAJB4 | DnaJ (Hsp40) homolog, subfamily B, member 4 |
| DNAJB9 | DnaJ (Hsp40) homolog, subfamily B, member 9 |
| FAM214B | family with sequence similarity 214, member B |
| FEM1B | fem-1 homolog b (C. elegans) |
| FER | fer (fps/fes related) tyrosine kinase |
| GABARAPL1 | GABA(A) receptor-associated protein like 1 |
| GCLC | glutamate-cysteine ligase, catalytic subunit |
| GCLM | glutamate-cysteine ligase, modifier subunit |
| GK | glycerol kinase |
| HEMK1 | HemK methyltransferase family member 1 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 |
| HMOX1 | heme oxygenase 1 |
| HSPA1A | heat shock 70kDa protein 1A |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') |
| IDS | iduronate 2-sulfatase |
| IKZF5 | IKAROS family zinc finger 5 (Pegasus) |
| IL15RA | interleukin 15 receptor, alpha |
| ISL1 | ISL LIM homeobox 1 |
| JUND | jun D proto-oncogene |
| KCTD15 | potassium channel tetramerization domain containing 15 |
| KIFC3 | kinesin family member C3 |
| KLHL25 | kelch-like family member 25 |
| LAMP1 | lysosomal-associated membrane protein 1 |
| LIG4 | ligase IV, DNA, ATP-dependent |
| MAP3K12 | mitogen-activated protein kinase kinase kinase 12 |
| MAX | MYC associated factor X |
| NFATC1 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 |
| NPHP1 | nephronophthisis 1 (juvenile) |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
| NUPR1 | nuclear protein, transcriptional regulator, 1 |
| NXPE3 | neurexophilin and PC-esterase domain family, member 3 |
| OSGIN1 | oxidative stress induced growth inhibitor 1 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II |
| PACS1 | phosphofurin acidic cluster sorting protein 1 |
| PHF7 | PHD finger protein 7 |
| PI4K2A | phosphatidylinositol 4-kinase type 2 alpha |
| PIK3CD | phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta |
| PLK3 | polo-like kinase 3 |
| PLSCR4 | phospholipid scramblase 4 |
| PTPN21 | protein tyrosine phosphatase, non-receptor type 21 |
| PXMP4 | peroxisomal membrane protein 4, 24kDa |
| RNASEH2B | ribonuclease H2, subunit B |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 |
| SLC22A5 | solute carrier family 22 (organic cation/carnitine transporter), member 5 |
| SLC35A2 | solute carrier family 35 (UDP-galactose transporter), member A2 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SNAPC4 | small nuclear RNA activating complex, polypeptide 4, 190kDa |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase |
| ST6GALNAC4 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4 |
| STOML1 | stomatin (EPB72)-like 1 |
| STX7 | syntaxin 7 |
| SYNGR1 | synaptogyrin 1 |
| TCTN1 | tectonic family member 1 |
| TDRKH | tudor and KH domain containing |
| TEX261 | testis expressed 261 |
| TMEM259 | transmembrane protein 259 |
| TPP1 | tripeptidyl peptidase I |
| TRIM16 | tripartite motif containing 16 |
| UROD | uroporphyrinogen decarboxylase |
| VPS33A | vacuolar protein sorting 33 homolog A (S. cerevisiae) |
| WDTC1 | WD and tetratricopeptide repeats 1 |
| ZBTB20 | zinc finger and BTB domain containing 20 |
| ZC2HC1C | zinc finger, C2HC-type containing 1C |
| ZNF37BP | zinc finger protein 37B, pseudogene |
| ZNF43 | zinc finger protein 43 |
| ZNF783 | zinc finger family member 783 |
| ZSCAN31 | zinc finger and SCAN domain containing 31 |
| Symbol | Name |
|---|---|
| ADAMTS3 | ADAM metallopeptidase with thrombospondin type 1 motif, 3 |
| ADRB2 | adrenoceptor beta 2, surface |
| ANKFY1 | ankyrin repeat and FYVE domain containing 1 |
| ARPIN | actin-related protein 2/3 complex inhibitor |
| ARRB1 | arrestin, beta 1 |
| ARSJ | arylsulfatase family, member J |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 |
| ATAD2 | ATPase family, AAA domain containing 2 |
| ATAD5 | ATPase family, AAA domain containing 5 |
| ATAT1 | alpha tubulin acetyltransferase 1 |
| ATG10 | autophagy related 10 |
| BEX4 | brain expressed, X-linked 4 |
| BMP4 | bone morphogenetic protein 4 |
| CAND2 | cullin-associated and neddylation-dissociated 2 (putative) |
| CD70 | CD70 molecule |
| CHMP6 | charged multivesicular body protein 6 |
| CHN1 | chimerin 1 |
| CISH | cytokine inducible SH2-containing protein |
| CLCN2 | chloride channel, voltage-sensitive 2 |
| CLN6 | ceroid-lipofuscinosis, neuronal 6, late infantile, variant |
| CLSTN3 | calsyntenin 3 |
| COL9A3 | collagen, type IX, alpha 3 |
| CSRNP3 | cysteine-serine-rich nuclear protein 3 |
| CTGF | connective tissue growth factor |
| DBF4B | DBF4 zinc finger B |
| DCAF4 | DDB1 and CUL4 associated factor 4 |
| DENND2D | DENN/MADD domain containing 2D |
| DHX57 | DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57 |
| DNAJA4 | DnaJ (Hsp40) homolog, subfamily A, member 4 |
| DNAJC28 | DnaJ (Hsp40) homolog, subfamily C, member 28 |
| DNMT3A | DNA (cytosine-5-)-methyltransferase 3 alpha |
| DPY19L2P2 | DPY19L2 pseudogene 2 |
| DUSP13 | dual specificity phosphatase 13 |
| FMO4 | flavin containing monooxygenase 4 |
| GBX2 | gastrulation brain homeobox 2 |
| GIT1 | G protein-coupled receptor kinase interacting ArfGAP 1 |
| GLB1L | galactosidase, beta 1-like |
| GLI3 | GLI family zinc finger 3 |
| GMIP | GEM interacting protein |
| GNL3LP1 | guanine nucleotide binding protein-like 3 (nucleolar)-like pseudogene 1 |
| GPR137B | G protein-coupled receptor 137B |
| H1F0 | H1 histone family, member 0 |
| HELLS | helicase, lymphoid-specific |
| HHLA1 | HERV-H LTR-associating 1 |
| HIST1H1D | histone cluster 1, H1d |
| HIST1H4C | histone cluster 1, H4c |
| HLA-DMB | major histocompatibility complex, class II, DM beta |
| HOXC10 | homeobox C10 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 |
| IFT54 | intraflagellar transport 54 |
| IGSF3 | immunoglobulin superfamily, member 3 |
| IL1B | interleukin 1, beta |
| INE1 | inactivation escape 1 (non-protein coding) |
| LOC730101 | uncharacterized LOC730101 |
| LRRK1 | leucine-rich repeat kinase 1 |
| MAP3K14 | mitogen-activated protein kinase kinase kinase 14 |
| MMP10 | matrix metallopeptidase 10 |
| MX1 | MX dynamin-like GTPase 1 |
| MXD3 | MAX dimerization protein 3 |
| MYH15 | myosin, heavy chain 15 |
| MYLK | myosin light chain kinase |
| NDE1 | nudE neurodevelopment protein 1 |
| NOD1 | nucleotide-binding oligomerization domain containing 1 |
| OR7A10 | olfactory receptor, family 7, subfamily A, member 10 |
| PARM1 | prostate androgen-regulated mucin-like protein 1 |
| PGGT1B | protein geranylgeranyltransferase type I, beta subunit |
| PHC1 | polyhomeotic homolog 1 (Drosophila) |
| PID1 | phosphotyrosine interaction domain containing 1 |
| PLEKHA6 | pleckstrin homology domain containing, family A member 6 |
| PODNL1 | podocan-like 1 |
| PRF1 | perforin 1 (pore forming protein) |
| PRKAA2 | protein kinase, AMP-activated, alpha 2 catalytic subunit |
| PRPF38B | pre-mRNA processing factor 38B |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 |
| PTX3 | pentraxin 3, long |
| RHOBTB2 | Rho-related BTB domain containing 2 |
| RUSC2 | RUN and SH3 domain containing 2 |
| SCAI | suppressor of cancer cell invasion |
| SCEL | sciellin |
| SCRG1 | stimulator of chondrogenesis 1 |
| SDC3 | syndecan 3 |
| SLC25A40 | solute carrier family 25, member 40 |
| SMPD2 | sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) |
| SNRPN | small nuclear ribonucleoprotein polypeptide N |
| SP4 | Sp4 transcription factor |
| SPATA7 | spermatogenesis associated 7 |
| SULT2B1 | sulfotransferase family, cytosolic, 2B, member 1 |
| SYNPO | synaptopodin |
| TAF4B | TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa |
| TAOK1 | TAO kinase 1 |
| TM4SF5 | transmembrane 4 L six family member 5 |
| TRAIP | TRAF interacting protein |
| TUBGCP5 | tubulin, gamma complex associated protein 5 |
| TXK | TXK tyrosine kinase |
| WDR47 | WD repeat domain 47 |
| WDR76 | WD repeat domain 76 |
| ZBTB38 | zinc finger and BTB domain containing 38 |
| ZNF219 | zinc finger protein 219 |
| ZNF667 | zinc finger protein 667 |
