| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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196 genes differentially expressed following the semustine-7540 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 |
| ADAM17 | ADAM metallopeptidase domain 17 |
| ADAP1 | ArfGAP with dual PH domains 1 |
| AFAP1 | actin filament associated protein 1 |
| AFF2 | AF4/FMR2 family, member 2 |
| AIRE | autoimmune regulator |
| AKR1C1 | aldo-keto reductase family 1, member C1 |
| AKR1C2 | aldo-keto reductase family 1, member C2 |
| AKR1C3 | aldo-keto reductase family 1, member C3 |
| ALDH4A1 | aldehyde dehydrogenase 4 family, member A1 |
| AP5Z1 | adaptor-related protein complex 5, zeta 1 subunit |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) |
| ATXN8OS | ATXN8 opposite strand (non-protein coding) |
| BBS9 | Bardet-Biedl syndrome 9 |
| BIN1 | bridging integrator 1 |
| BTN2A1 | butyrophilin, subfamily 2, member A1 |
| BTN2A3P | butyrophilin, subfamily 2, member A3, pseudogene |
| CA5BP1 | carbonic anhydrase VB pseudogene 1 |
| CCDC40 | coiled-coil domain containing 40 |
| CCT6B | chaperonin containing TCP1, subunit 6B (zeta 2) |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CPA4 | carboxypeptidase A4 |
| CTBS | chitobiase, di-N-acetyl- |
| CTIF | CBP80/20-dependent translation initiation factor |
| DDR1-AS1 | DDR1 antisense RNA 1 (head to head) |
| DOCK6 | dedicator of cytokinesis 6 |
| EN2 | engrailed homeobox 2 |
| EPB41L4B | erythrocyte membrane protein band 4.1 like 4B |
| ETV5 | ets variant 5 |
| FAM134B | family with sequence similarity 134, member B |
| FOSL1 | FOS-like antigen 1 |
| FSCN1 | fascin actin-bundling protein 1 |
| GALE | UDP-galactose-4-epimerase |
| GCLM | glutamate-cysteine ligase, modifier subunit |
| HABP4 | hyaluronan binding protein 4 |
| HERC5 | HECT and RLD domain containing E3 ubiquitin protein ligase 5 |
| HMOX1 | heme oxygenase 1 |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') |
| HYMAI | hydatidiform mole associated and imprinted (non-protein coding) |
| IL15RA | interleukin 15 receptor, alpha |
| ISG20 | interferon stimulated exonuclease gene 20kDa |
| KCNAB2 | potassium channel, voltage gated subfamily A regulatory beta subunit 2 |
| KCNQ3 | potassium channel, voltage gated KQT-like subfamily Q, member 3 |
| KIAA0513 | KIAA0513 |
| KLF2 | Kruppel-like factor 2 |
| KRIT1 | KRIT1, ankyrin repeat containing |
| LAMP1 | lysosomal-associated membrane protein 1 |
| LMF1 | lipase maturation factor 1 |
| LMO4 | LIM domain only 4 |
| LSS | lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MED28 | mediator complex subunit 28 |
| MPP3 | membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3) |
| MTM1 | myotubularin 1 |
| NUPR1 | nuclear protein, transcriptional regulator, 1 |
| ONECUT2 | one cut homeobox 2 |
| OSGIN1 | oxidative stress induced growth inhibitor 1 |
| OTUB2 | OTU deubiquitinase, ubiquitin aldehyde binding 2 |
| PDLIM5 | PDZ and LIM domain 5 |
| PGBD5 | piggyBac transposable element derived 5 |
| PIN4 | peptidylprolyl cis/trans isomerase, NIMA-interacting 4 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 |
| PPP2R3A | protein phosphatase 2, regulatory subunit B'', alpha |
| PPT2 | palmitoyl-protein thioesterase 2 |
| PSD4 | pleckstrin and Sec7 domain containing 4 |
| RAB3IL1 | RAB3A interacting protein (rabin3)-like 1 |
| RABGAP1 | RAB GTPase activating protein 1 |
| RARA | retinoic acid receptor, alpha |
| RCN1 | reticulocalbin 1, EF-hand calcium binding domain |
| RFPL2 | ret finger protein-like 2 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 |
| RPS6KA5 | ribosomal protein S6 kinase, 90kDa, polypeptide 5 |
| RUFY3 | RUN and FYVE domain containing 3 |
| SDC3 | syndecan 3 |
| SGSM3 | small G protein signaling modulator 3 |
| SH3BP2 | SH3-domain binding protein 2 |
| SIK3 | SIK family kinase 3 |
| SLC1A4 | solute carrier family 1 (glutamate/neutral amino acid transporter), member 4 |
| SLC25A16 | solute carrier family 25 (mitochondrial carrier), member 16 |
| SLC48A1 | solute carrier family 48 (heme transporter), member 1 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SMIM14 | small integral membrane protein 14 |
| SQSTM1 | sequestosome 1 |
| STK24 | serine/threonine kinase 24 |
| STOML1 | stomatin (EPB72)-like 1 |
| SUGP1 | SURP and G patch domain containing 1 |
| TES | testin LIM domain protein |
| TK2 | thymidine kinase 2, mitochondrial |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b |
| TRIM16 | tripartite motif containing 16 |
| TRIO | trio Rho guanine nucleotide exchange factor |
| TRPV1 | transient receptor potential cation channel, subfamily V, member 1 |
| TSC22D4 | TSC22 domain family, member 4 |
| TXNRD1 | thioredoxin reductase 1 |
| UBB | ubiquitin B |
| ZNF205 | zinc finger protein 205 |
| ZNF45 | zinc finger protein 45 |
| ZNF79 | zinc finger protein 79 |
| Symbol | Name |
|---|---|
| A2M | alpha-2-macroglobulin |
| ADAP2 | ArfGAP with dual PH domains 2 |
| ADCY6 | adenylate cyclase 6 |
| AHCTF1 | AT hook containing transcription factor 1 |
| ALOX15 | arachidonate 15-lipoxygenase |
| ANP32A-IT1 | ANP32A intronic transcript 1 |
| ARHGDIG | Rho GDP dissociation inhibitor (GDI) gamma |
| B3GNT3 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3 |
| BCL11B | B-cell CLL/lymphoma 11B (zinc finger protein) |
| BHLHB9 | basic helix-loop-helix domain containing, class B, 9 |
| CEBPZ | CCAAT/enhancer binding protein (C/EBP), zeta |
| CES3 | carboxylesterase 3 |
| CLDN15 | claudin 15 |
| CLSTN2 | calsyntenin 2 |
| CNNM4 | cyclin and CBS domain divalent metal cation transport mediator 4 |
| CNTD2 | cyclin N-terminal domain containing 2 |
| COL9A2 | collagen, type IX, alpha 2 |
| CORO7 | coronin 7 |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 |
| DHRS1 | dehydrogenase/reductase (SDR family) member 1 |
| DNAJC22 | DnaJ (Hsp40) homolog, subfamily C, member 22 |
| DOCK1 | dedicator of cytokinesis 1 |
| DYRK4 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4 |
| ETV6 | ets variant 6 |
| ETV7 | ets variant 7 |
| FAM212B | family with sequence similarity 212, member B |
| FKRP | fukutin related protein |
| FLJ11710 | uncharacterized protein FLJ11710 |
| FZD2 | frizzled class receptor 2 |
| GLI3 | GLI family zinc finger 3 |
| GMEB1 | glucocorticoid modulatory element binding protein 1 |
| GNG13 | guanine nucleotide binding protein (G protein), gamma 13 |
| GNL3LP1 | guanine nucleotide binding protein-like 3 (nucleolar)-like pseudogene 1 |
| GTF2A1 | general transcription factor IIA, 1, 19/37kDa |
| HIST1H2AJ | histone cluster 1, H2aj |
| HTR1E | 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled |
| IFI6 | interferon, alpha-inducible protein 6 |
| JADE1 | jade family PHD finger 1 |
| KIAA0125 | KIAA0125 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) |
| KLHL25 | kelch-like family member 25 |
| LCP1 | lymphocyte cytosolic protein 1 (L-plastin) |
| LGR4 | leucine-rich repeat containing G protein-coupled receptor 4 |
| LNPEP | leucyl/cystinyl aminopeptidase |
| LRRC8E | leucine rich repeat containing 8 family, member E |
| MAGEF1 | melanoma antigen family F1 |
| MAPK12 | mitogen-activated protein kinase 12 |
| NARFL | nuclear prelamin A recognition factor-like |
| NFKBIE | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon |
| NKX3-2 | NK3 homeobox 2 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa |
| OPA3 | optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia) |
| PHC1 | polyhomeotic homolog 1 (Drosophila) |
| PIGQ | phosphatidylinositol glycan anchor biosynthesis, class Q |
| PKIA | protein kinase (cAMP-dependent, catalytic) inhibitor alpha |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) |
| PLXNB3 | plexin B3 |
| PORCN | porcupine homolog (Drosophila) |
| PPIP5K2 | diphosphoinositol pentakisphosphate kinase 2 |
| PPP1R14D | protein phosphatase 1, regulatory (inhibitor) subunit 14D |
| PRODH | proline dehydrogenase (oxidase) 1 |
| PRPH | peripherin |
| PRR15L | proline rich 15-like |
| PSTPIP2 | proline-serine-threonine phosphatase interacting protein 2 |
| PTPRE | protein tyrosine phosphatase, receptor type, E |
| PTTG3P | pituitary tumor-transforming 3, pseudogene |
| RAB8B | RAB8B, member RAS oncogene family |
| RNF126P1 | ring finger protein 126 pseudogene 1 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase |
| RNF25 | ring finger protein 25 |
| RPRM | reprimo, TP53 dependent G2 arrest mediator candidate |
| RSF1 | remodeling and spacing factor 1 |
| SALL2 | spalt-like transcription factor 2 |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 |
| SLC22A18AS | solute carrier family 22 (organic cation transporter), member 18 antisense |
| SLC22A4 | solute carrier family 22 (organic cation/zwitterion transporter), member 4 |
| SLC25A21 | solute carrier family 25 (mitochondrial oxoadipate carrier), member 21 |
| SLC2A9 | solute carrier family 2 (facilitated glucose transporter), member 9 |
| SMAD7 | SMAD family member 7 |
| SNAPC2 | small nuclear RNA activating complex, polypeptide 2, 45kDa |
| SNX15 | sorting nexin 15 |
| SOAT2 | sterol O-acyltransferase 2 |
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 |
| TAOK1 | TAO kinase 1 |
| TCTN1 | tectonic family member 1 |
| TIGD6 | tigger transposable element derived 6 |
| TMEM53 | transmembrane protein 53 |
| UBE2L6 | ubiquitin-conjugating enzyme E2L 6 |
| WLS | wntless Wnt ligand secretion mediator |
| WWC2 | WW and C2 domain containing 2 |
| ZBTB48 | zinc finger and BTB domain containing 48 |
| ZFP69B | ZFP69 zinc finger protein B |
| ZNF33B | zinc finger protein 33B |
| ZNF358 | zinc finger protein 358 |
| ZNF362 | zinc finger protein 362 |
| ZNF646 | zinc finger protein 646 |
| ZNF767P | zinc finger family member 767, pseudogene |
