| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the seneciphylline-2140 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABHD6 | abhydrolase domain containing 6 |
| ABI3BP | ABI family, member 3 (NESH) binding protein |
| ADAM28 | ADAM metallopeptidase domain 28 |
| ADM | adrenomedullin |
| APAF1 | apoptotic peptidase activating factor 1 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 |
| ARHGAP44 | Rho GTPase activating protein 44 |
| ATP13A2 | ATPase type 13A2 |
| B9D2 | B9 protein domain 2 |
| BET1L | Bet1 golgi vesicular membrane trafficking protein-like |
| C19ORF73 | chromosome 19 open reading frame 73 |
| C1ORF105 | chromosome 1 open reading frame 105 |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) |
| CEP68 | centrosomal protein 68kDa |
| CHRNA2 | cholinergic receptor, nicotinic, alpha 2 (neuronal) |
| COLQ | collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase |
| CRABP2 | cellular retinoic acid binding protein 2 |
| CREM | cAMP responsive element modulator |
| CUL5 | cullin 5 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 |
| CYTH1 | cytohesin 1 |
| CYTH4 | cytohesin 4 |
| DCAF13 | DDB1 and CUL4 associated factor 13 |
| DDAH2 | dimethylarginine dimethylaminohydrolase 2 |
| DDR1 | discoidin domain receptor tyrosine kinase 1 |
| DNMT3A | DNA (cytosine-5-)-methyltransferase 3 alpha |
| EFNA4 | ephrin-A4 |
| EFR3B | EFR3 homolog B (S. cerevisiae) |
| EYA3 | EYA transcriptional coactivator and phosphatase 3 |
| EZH1 | enhancer of zeste 1 polycomb repressive complex 2 subunit |
| FAM65A | family with sequence similarity 65, member A |
| FCAR | Fc fragment of IgA receptor |
| FZD3 | frizzled class receptor 3 |
| GALC | galactosylceramidase |
| GPR19 | G protein-coupled receptor 19 |
| HAMP | hepcidin antimicrobial peptide |
| HEG1 | heart development protein with EGF-like domains 1 |
| HIST1H4E | histone cluster 1, H4e |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
| IL17RC | interleukin 17 receptor C |
| ITGB5 | integrin, beta 5 |
| KCNQ1 | potassium channel, voltage gated KQT-like subfamily Q, member 1 |
| KIAA0319L | KIAA0319-like |
| KLHL36 | kelch-like family member 36 |
| LMF1 | lipase maturation factor 1 |
| MAP4 | microtubule-associated protein 4 |
| MRPS12 | mitochondrial ribosomal protein S12 |
| MXD4 | MAX dimerization protein 4 |
| MYL4 | myosin, light chain 4, alkali; atrial, embryonic |
| NEK9 | NIMA-related kinase 9 |
| NLRP1 | NLR family, pyrin domain containing 1 |
| NNAT | neuronatin |
| NOX5 | NADPH oxidase, EF-hand calcium binding domain 5 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
| NUP88 | nucleoporin 88kDa |
| NXPE3 | neurexophilin and PC-esterase domain family, member 3 |
| OR2B6 | olfactory receptor, family 2, subfamily B, member 6 |
| PADI2 | peptidyl arginine deiminase, type II |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 |
| PHC1 | polyhomeotic homolog 1 (Drosophila) |
| PPARD | peroxisome proliferator-activated receptor delta |
| PPP1R12B | protein phosphatase 1, regulatory subunit 12B |
| PRKAR2A | protein kinase, cAMP-dependent, regulatory, type II, alpha |
| PRKCA | protein kinase C, alpha |
| PTGDS | prostaglandin D2 synthase 21kDa (brain) |
| PYGB | phosphorylase, glycogen; brain |
| RAD51B | RAD51 paralog B |
| RGS12 | regulator of G-protein signaling 12 |
| RUNDC3B | RUN domain containing 3B |
| SAMD4A | sterile alpha motif domain containing 4A |
| SCAI | suppressor of cancer cell invasion |
| SCAND2P | SCAN domain containing 2 pseudogene |
| SERPINA5 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 |
| SH3BP1 | SH3-domain binding protein 1 |
| SH3BP5 | SH3-domain binding protein 5 (BTK-associated) |
| SNTB2 | syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2) |
| SPATA20 | spermatogenesis associated 20 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 |
| TAGLN3 | transgelin 3 |
| TAPT1 | transmembrane anterior posterior transformation 1 |
| TBC1D30 | TBC1 domain family, member 30 |
| TCP10 | t-complex 10 |
| TNFRSF10D | tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain |
| TRAF1 | TNF receptor-associated factor 1 |
| TRIM62 | tripartite motif containing 62 |
| TSKS | testis-specific serine kinase substrate |
| TUBB2A | tubulin, beta 2A class IIa |
| UBE2I | ubiquitin-conjugating enzyme E2I |
| UPP1 | uridine phosphorylase 1 |
| VAC14 | Vac14 homolog (S. cerevisiae) |
| VSNL1 | visinin-like 1 |
| WDR59 | WD repeat domain 59 |
| ZCCHC24 | zinc finger, CCHC domain containing 24 |
| ZER1 | zyg-11 related, cell cycle regulator |
| ZMYND8 | zinc finger, MYND-type containing 8 |
| ZNF276 | zinc finger protein 276 |
| ZNF609 | zinc finger protein 609 |
| ZNF668 | zinc finger protein 668 |
| ZNF76 | zinc finger protein 76 |
| Symbol | Name |
|---|---|
| A2M | alpha-2-macroglobulin |
| ADAMTS5 | ADAM metallopeptidase with thrombospondin type 1 motif, 5 |
| AHCTF1 | AT hook containing transcription factor 1 |
| APOBEC3C | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C |
| ARHGEF10L | Rho guanine nucleotide exchange factor (GEF) 10-like |
| ARSB | arylsulfatase B |
| BTBD18 | BTB (POZ) domain containing 18 |
| C14ORF93 | chromosome 14 open reading frame 93 |
| C16ORF59 | chromosome 16 open reading frame 59 |
| C22ORF29 | chromosome 22 open reading frame 29 |
| C7ORF43 | chromosome 7 open reading frame 43 |
| CBX4 | chromobox homolog 4 |
| CCDC85C | coiled-coil domain containing 85C |
| CD82 | CD82 molecule |
| CHRNA9 | cholinergic receptor, nicotinic, alpha 9 (neuronal) |
| CIDEC | cell death-inducing DFFA-like effector c |
| CLN6 | ceroid-lipofuscinosis, neuronal 6, late infantile, variant |
| CYP17A1 | cytochrome P450, family 17, subfamily A, polypeptide 1 |
| DDX6 | DEAD (Asp-Glu-Ala-Asp) box helicase 6 |
| DGKG | diacylglycerol kinase, gamma 90kDa |
| DNAL4 | dynein, axonemal, light chain 4 |
| DNMT3B | DNA (cytosine-5-)-methyltransferase 3 beta |
| ERCC2 | excision repair cross-complementation group 2 |
| FBP1 | fructose-1,6-bisphosphatase 1 |
| FBRS | fibrosin |
| FCGR1A | Fc fragment of IgG, high affinity Ia, receptor (CD64) |
| FICD | FIC domain containing |
| FKBP9 | FK506 binding protein 9, 63 kDa |
| FOXC1 | forkhead box C1 |
| GABRB2 | gamma-aminobutyric acid (GABA) A receptor, beta 2 |
| GABRR2 | gamma-aminobutyric acid (GABA) A receptor, rho 2 |
| GALNT12 | polypeptide N-acetylgalactosaminyltransferase 12 |
| GEMIN8 | gem (nuclear organelle) associated protein 8 |
| GIT1 | G protein-coupled receptor kinase interacting ArfGAP 1 |
| GLCE | glucuronic acid epimerase |
| GNG4 | guanine nucleotide binding protein (G protein), gamma 4 |
| GRINA | glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding) |
| GRIP2 | glutamate receptor interacting protein 2 |
| GSTT1 | glutathione S-transferase theta 1 |
| HIST1H4D | histone cluster 1, H4d |
| HYAL2 | hyaluronoglucosaminidase 2 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 |
| INO80D | INO80 complex subunit D |
| KCNMB4 | potassium channel subfamily M regulatory beta subunit 4 |
| KDELR1 | KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 |
| KHDRBS3 | KH domain containing, RNA binding, signal transduction associated 3 |
| KIAA0754 | KIAA0754 |
| LNPEP | leucyl/cystinyl aminopeptidase |
| LRP5 | low density lipoprotein receptor-related protein 5 |
| LRRK1 | leucine-rich repeat kinase 1 |
| LY6G6C | lymphocyte antigen 6 complex, locus G6C |
| MAGEH1 | melanoma antigen family H1 |
| MED15 | mediator complex subunit 15 |
| MLC1 | megalencephalic leukoencephalopathy with subcortical cysts 1 |
| NCALD | neurocalcin delta |
| NT5DC3 | 5'-nucleotidase domain containing 3 |
| NUDT6 | nudix (nucleoside diphosphate linked moiety X)-type motif 6 |
| OXTR | oxytocin receptor |
| PEX26 | peroxisomal biogenesis factor 26 |
| PIK3R2 | phosphoinositide-3-kinase, regulatory subunit 2 (beta) |
| PLTP | phospholipid transfer protein |
| PMFBP1 | polyamine modulated factor 1 binding protein 1 |
| PMP22 | peripheral myelin protein 22 |
| PRR4 | proline rich 4 (lacrimal) |
| RAB11FIP5 | RAB11 family interacting protein 5 (class I) |
| RAB33A | RAB33A, member RAS oncogene family |
| RAB3IL1 | RAB3A interacting protein (rabin3)-like 1 |
| RABL6 | RAB, member RAS oncogene family-like 6 |
| RHOBTB2 | Rho-related BTB domain containing 2 |
| RNF39 | ring finger protein 39 |
| S1PR4 | sphingosine-1-phosphate receptor 4 |
| SCG5 | secretogranin V |
| SCGB2A2 | secretoglobin, family 2A, member 2 |
| SIGLEC15 | sialic acid binding Ig-like lectin 15 |
| SLC29A3 | solute carrier family 29 (equilibrative nucleoside transporter), member 3 |
| SNAI1 | snail family zinc finger 1 |
| SNX29P2 | sorting nexin 29 pseudogene 2 |
| SP4 | Sp4 transcription factor |
| STAG3 | stromal antigen 3 |
| STAG3L4 | stromal antigen 3-like 4 (pseudogene) |
| SUOX | sulfite oxidase |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa |
| TGFBRAP1 | transforming growth factor, beta receptor associated protein 1 |
| TM7SF2 | transmembrane 7 superfamily member 2 |
| TMEM120B | transmembrane protein 120B |
| TMEM184C | transmembrane protein 184C |
| TMEM212 | transmembrane protein 212 |
| TMEM53 | transmembrane protein 53 |
| TRPV1 | transient receptor potential cation channel, subfamily V, member 1 |
| TTC23 | tetratricopeptide repeat domain 23 |
| TUT1 | terminal uridylyl transferase 1, U6 snRNA-specific |
| UBL4A | ubiquitin-like 4A |
| WASF3 | WAS protein family, member 3 |
| ZFHX2 | zinc finger homeobox 2 |
| ZKSCAN3 | zinc finger with KRAB and SCAN domains 3 |
| ZNF185 | zinc finger protein 185 (LIM domain) |
| ZNF749 | zinc finger protein 749 |
| ZSCAN31 | zinc finger and SCAN domain containing 31 |
