| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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199 genes differentially expressed following the seneciphylline-2797 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCA2 | ATP-binding cassette, sub-family A (ABC1), member 2 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 |
| ADAM22 | ADAM metallopeptidase domain 22 |
| ADAMTS12 | ADAM metallopeptidase with thrombospondin type 1 motif, 12 |
| ANXA2P3 | annexin A2 pseudogene 3 |
| ARNT | aryl hydrocarbon receptor nuclear translocator |
| ART1 | ADP-ribosyltransferase 1 |
| ARVCF | armadillo repeat gene deleted in velocardiofacial syndrome |
| ATG10 | autophagy related 10 |
| ATXN3 | ataxin 3 |
| BPIFA1 | BPI fold containing family A, member 1 |
| C1QTNF1 | C1q and tumor necrosis factor related protein 1 |
| CACNA1H | calcium channel, voltage-dependent, T type, alpha 1H subunit |
| CAMSAP1 | calmodulin regulated spectrin-associated protein 1 |
| CD7 | CD7 molecule |
| CEACAM3 | carcinoembryonic antigen-related cell adhesion molecule 3 |
| CHI3L2 | chitinase 3-like 2 |
| CHRNB2 | cholinergic receptor, nicotinic, beta 2 (neuronal) |
| CLCF1 | cardiotrophin-like cytokine factor 1 |
| CLEC11A | C-type lectin domain family 11, member A |
| CLIC5 | chloride intracellular channel 5 |
| CTDP1 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1 |
| CUL9 | cullin 9 |
| DCN | decorin |
| DLL3 | delta-like 3 (Drosophila) |
| ELAC2 | elaC ribonuclease Z 2 |
| EMC1 | ER membrane protein complex subunit 1 |
| EPHA1 | EPH receptor A1 |
| FBXO41 | F-box protein 41 |
| FEZ1 | fasciculation and elongation protein zeta 1 (zygin I) |
| FGF5 | fibroblast growth factor 5 |
| FGR | FGR proto-oncogene, Src family tyrosine kinase |
| FH | fumarate hydratase |
| FLJ20712 | uncharacterized FLJ20712 |
| FLJ22184 | |
| FOSL1 | FOS-like antigen 1 |
| FOXP3 | forkhead box P3 |
| FUT3 | fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group) |
| GFER | growth factor, augmenter of liver regeneration |
| GMPR | guanosine monophosphate reductase |
| GSK3A | glycogen synthase kinase 3 alpha |
| HPS1 | Hermansky-Pudlak syndrome 1 |
| IL2RG | interleukin 2 receptor, gamma |
| INHBE | inhibin, beta E |
| ITPKB | inositol-trisphosphate 3-kinase B |
| KCNS1 | potassium voltage-gated channel, modifier subfamily S, member 1 |
| KCTD17 | potassium channel tetramerization domain containing 17 |
| KLHL25 | kelch-like family member 25 |
| LAMC2 | laminin, gamma 2 |
| LDLRAD4 | low density lipoprotein receptor class A domain containing 4 |
| LPPR2 | lipid phosphate phosphatase-related protein type 2 |
| LTBP4 | latent transforming growth factor beta binding protein 4 |
| MAL | mal, T-cell differentiation protein |
| MAP2K5 | mitogen-activated protein kinase kinase 5 |
| MAP4 | microtubule-associated protein 4 |
| MTSS1 | metastasis suppressor 1 |
| MXD4 | MAX dimerization protein 4 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase |
| NR6A1 | nuclear receptor subfamily 6, group A, member 1 |
| ONECUT2 | one cut homeobox 2 |
| OR1F1 | olfactory receptor, family 1, subfamily F, member 1 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 |
| PAX5 | paired box 5 |
| PCDHB12 | protocadherin beta 12 |
| PCSK6 | proprotein convertase subtilisin/kexin type 6 |
| PDE8B | phosphodiesterase 8B |
| PITX1 | paired-like homeodomain 1 |
| PKNOX2 | PBX/knotted 1 homeobox 2 |
| POM121L2 | POM121 transmembrane nucleoporin-like 2 |
| POU2F3 | POU class 2 homeobox 3 |
| PPP5C | protein phosphatase 5, catalytic subunit |
| PRPH2 | peripherin 2 (retinal degeneration, slow) |
| PTHLH | parathyroid hormone-like hormone |
| RAD54L2 | RAD54-like 2 (S. cerevisiae) |
| RBMS2 | RNA binding motif, single stranded interacting protein 2 |
| RGS12 | regulator of G-protein signaling 12 |
| RUFY3 | RUN and FYVE domain containing 3 |
| S100A9 | S100 calcium binding protein A9 |
| SGSH | N-sulfoglucosamine sulfohydrolase |
| SLC2A5 | solute carrier family 2 (facilitated glucose/fructose transporter), member 5 |
| SLCO1A2 | solute carrier organic anion transporter family, member 1A2 |
| SPAM1 | sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding) |
| STK10 | serine/threonine kinase 10 |
| STK24 | serine/threonine kinase 24 |
| SUPT6H | suppressor of Ty 6 homolog (S. cerevisiae) |
| TAGLN3 | transgelin 3 |
| TGFB1 | transforming growth factor, beta 1 |
| TJAP1 | tight junction associated protein 1 (peripheral) |
| TLDC1 | TBC/LysM-associated domain containing 1 |
| UBE3A | ubiquitin protein ligase E3A |
| UGT8 | UDP glycosyltransferase 8 |
| UTY | ubiquitously transcribed tetratricopeptide repeat containing, Y-linked |
| VAC14 | Vac14 homolog (S. cerevisiae) |
| VDR | vitamin D (1,25- dihydroxyvitamin D3) receptor |
| ZBTB7A | zinc finger and BTB domain containing 7A |
| ZC3H3 | zinc finger CCCH-type containing 3 |
| ZC3H7B | zinc finger CCCH-type containing 7B |
| ZMIZ2 | zinc finger, MIZ-type containing 2 |
| ZNF446 | zinc finger protein 446 |
| Symbol | Name |
|---|---|
| ACTR8 | ARP8 actin-related protein 8 homolog (yeast) |
| ADPRM | ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent |
| ANAPC2 | anaphase promoting complex subunit 2 |
| APOLD1 | apolipoprotein L domain containing 1 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) |
| BAGE | B melanoma antigen |
| BAX | BCL2-associated X protein |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 |
| C17ORF80 | chromosome 17 open reading frame 80 |
| CASP3 | caspase 3, apoptosis-related cysteine peptidase |
| CCNT1 | cyclin T1 |
| CCT6B | chaperonin containing TCP1, subunit 6B (zeta 2) |
| CDK20 | cyclin-dependent kinase 20 |
| CLCN5 | chloride channel, voltage-sensitive 5 |
| CRABP1 | cellular retinoic acid binding protein 1 |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 |
| CYP26A1 | cytochrome P450, family 26, subfamily A, polypeptide 1 |
| DDA1 | DET1 and DDB1 associated 1 |
| DEAF1 | DEAF1 transcription factor |
| DGKE | diacylglycerol kinase, epsilon 64kDa |
| DUSP2 | dual specificity phosphatase 2 |
| EIF5A2 | eukaryotic translation initiation factor 5A2 |
| ERCC4 | excision repair cross-complementation group 4 |
| ERF | Ets2 repressor factor |
| ETAA1 | Ewing tumor-associated antigen 1 |
| FAM188A | family with sequence similarity 188, member A |
| FAM204A | family with sequence similarity 204, member A |
| FBXO5 | F-box protein 5 |
| FKBP10 | FK506 binding protein 10, 65 kDa |
| FKBP5 | FK506 binding protein 5 |
| GDPD3 | glycerophosphodiester phosphodiesterase domain containing 3 |
| GLS2 | glutaminase 2 (liver, mitochondrial) |
| GNA13 | guanine nucleotide binding protein (G protein), alpha 13 |
| GTF2I | general transcription factor IIi |
| H1F0 | H1 histone family, member 0 |
| HIST1H2AJ | histone cluster 1, H2aj |
| HIST1H3E | histone cluster 1, H3e |
| HP1BP3 | heterochromatin protein 1, binding protein 3 |
| HSD17B1 | hydroxysteroid (17-beta) dehydrogenase 1 |
| IDI2-AS1 | IDI2 antisense RNA 1 |
| IRX4 | iroquois homeobox 4 |
| KCNJ3 | potassium channel, inwardly rectifying subfamily J, member 3 |
| KCTD20 | potassium channel tetramerization domain containing 20 |
| KIAA0125 | KIAA0125 |
| KPTN | kaptin (actin binding protein) |
| LGMN | legumain |
| LMNB1 | lamin B1 |
| LRFN3 | leucine rich repeat and fibronectin type III domain containing 3 |
| LYPD1 | LY6/PLAUR domain containing 1 |
| MDM4 | MDM4, p53 regulator |
| METTL16 | methyltransferase like 16 |
| MGC12488 | |
| MPDU1 | mannose-P-dolichol utilization defect 1 |
| MSRA | methionine sulfoxide reductase A |
| MTMR6 | myotubularin related protein 6 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric |
| MYL5 | myosin, light chain 5, regulatory |
| NFE2L3 | nuclear factor, erythroid 2-like 3 |
| NME6 | NME/NM23 nucleoside diphosphate kinase 6 |
| NPY1R | neuropeptide Y receptor Y1 |
| NPY5R | neuropeptide Y receptor Y5 |
| NUP62CL | nucleoporin 62kDa C-terminal like |
| PARD6B | par-6 family cell polarity regulator beta |
| PCDHA9 | protocadherin alpha 9 |
| PCSK1N | proprotein convertase subtilisin/kexin type 1 inhibitor |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) |
| PLEKHB1 | pleckstrin homology domain containing, family B (evectins) member 1 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor |
| PRR3 | proline rich 3 |
| PRSS16 | protease, serine, 16 (thymus) |
| PSENEN | presenilin enhancer gamma secretase subunit |
| RAB30 | RAB30, member RAS oncogene family |
| RANGRF | RAN guanine nucleotide release factor |
| RBM42 | RNA binding motif protein 42 |
| RPS10P5 | ribosomal protein S10 pseudogene 5 |
| SCYL2 | SCY1-like 2 (S. cerevisiae) |
| SENP7 | SUMO1/sentrin specific peptidase 7 |
| SIX1 | SIX homeobox 1 |
| SLC46A3 | solute carrier family 46, member 3 |
| SLC4A8 | solute carrier family 4, sodium bicarbonate cotransporter, member 8 |
| SMPD2 | sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) |
| SNORA21 | small nucleolar RNA, H/ACA box 21 |
| SPRYD7 | SPRY domain containing 7 |
| SSR3 | signal sequence receptor, gamma (translocon-associated protein gamma) |
| STK16 | serine/threonine kinase 16 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa |
| TARP | TCR gamma alternate reading frame protein |
| TEAD3 | TEA domain family member 3 |
| TK1 | thymidine kinase 1, soluble |
| TMEM208 | transmembrane protein 208 |
| TMEM209 | transmembrane protein 209 |
| TRIM21 | tripartite motif containing 21 |
| TSSC4 | tumor suppressing subtransferable candidate 4 |
| UBXN8 | UBX domain protein 8 |
| ULBP2 | UL16 binding protein 2 |
| USP27X | ubiquitin specific peptidase 27, X-linked |
| VASH2 | vasohibin 2 |
| ZBTB6 | zinc finger and BTB domain containing 6 |
| ZMAT5 | zinc finger, matrin-type 5 |
| ZNF480 | zinc finger protein 480 |
