| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the seneciphylline-4238 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACAN | aggrecan |
| ACSBG1 | acyl-CoA synthetase bubblegum family member 1 |
| ADAMTS12 | ADAM metallopeptidase with thrombospondin type 1 motif, 12 |
| ANGEL2 | angel homolog 2 (Drosophila) |
| ASPN | asporin |
| ATP2C2 | ATPase, Ca++ transporting, type 2C, member 2 |
| ATP6V0A1 | ATPase, H+ transporting, lysosomal V0 subunit a1 |
| ATP6V0A4 | ATPase, H+ transporting, lysosomal V0 subunit a4 |
| BTBD18 | BTB (POZ) domain containing 18 |
| BTF3P11 | basic transcription factor 3 pseudogene 11 |
| CAMSAP1 | calmodulin regulated spectrin-associated protein 1 |
| CD248 | CD248 molecule, endosialin |
| CEACAM4 | carcinoembryonic antigen-related cell adhesion molecule 4 |
| CHODL | chondrolectin |
| CNNM4 | cyclin and CBS domain divalent metal cation transport mediator 4 |
| COL14A1 | collagen, type XIV, alpha 1 |
| COMT | catechol-O-methyltransferase |
| CSDC2 | cold shock domain containing C2, RNA binding |
| CTDSPL | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like |
| CTNS | cystinosin, lysosomal cystine transporter |
| DGKE | diacylglycerol kinase, epsilon 64kDa |
| DNAJB12 | DnaJ (Hsp40) homolog, subfamily B, member 12 |
| DRD2 | dopamine receptor D2 |
| DYNC1LI2 | dynein, cytoplasmic 1, light intermediate chain 2 |
| EIF3F | eukaryotic translation initiation factor 3, subunit F |
| ENC1 | ectodermal-neural cortex 1 (with BTB domain) |
| EPX | eosinophil peroxidase |
| ETV6 | ets variant 6 |
| FILIP1L | filamin A interacting protein 1-like |
| FLJ11710 | uncharacterized protein FLJ11710 |
| FPR2 | formyl peptide receptor 2 |
| FUT6 | fucosyltransferase 6 (alpha (1,3) fucosyltransferase) |
| GAL | galanin/GMAP prepropeptide |
| GAL3ST4 | galactose-3-O-sulfotransferase 4 |
| GJA4 | gap junction protein, alpha 4, 37kDa |
| GZMK | granzyme K (granzyme 3; tryptase II) |
| HGD | homogentisate 1,2-dioxygenase |
| HIST1H4C | histone cluster 1, H4c |
| HRG | histidine-rich glycoprotein |
| ING2 | inhibitor of growth family, member 2 |
| INHBC | inhibin, beta C |
| ITGA2B | integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41) |
| KANSL1L | KAT8 regulatory NSL complex subunit 1-like |
| KCNE1 | potassium channel, voltage gated subfamily E regulatory beta subunit 1 |
| KCNIP1 | Kv channel interacting protein 1 |
| KLF4 | Kruppel-like factor 4 (gut) |
| LLGL1 | lethal giant larvae homolog 1 (Drosophila) |
| LOC100287387 | uncharacterized LOC100287387 |
| MAPK11 | mitogen-activated protein kinase 11 |
| MFAP3L | microfibrillar-associated protein 3-like |
| MFHAS1 | malignant fibrous histiocytoma amplified sequence 1 |
| MMP11 | matrix metallopeptidase 11 |
| MST1 | macrophage stimulating 1 |
| NEK9 | NIMA-related kinase 9 |
| NFASC | neurofascin |
| NPTX1 | neuronal pentraxin I |
| NPY6R | neuropeptide Y receptor Y6 (pseudogene) |
| NTRK3 | neurotrophic tyrosine kinase, receptor, type 3 |
| NXPH3 | neurexophilin 3 |
| OSBPL10 | oxysterol binding protein-like 10 |
| PHLPP2 | PH domain and leucine rich repeat protein phosphatase 2 |
| PIK3R4 | phosphoinositide-3-kinase, regulatory subunit 4 |
| PITX2 | paired-like homeodomain 2 |
| PKP4 | plakophilin 4 |
| PLA2G7 | phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) |
| PLCL2 | phospholipase C-like 2 |
| PLEKHF1 | pleckstrin homology domain containing, family F (with FYVE domain) member 1 |
| PPARD | peroxisome proliferator-activated receptor delta |
| PPFIBP2 | PTPRF interacting protein, binding protein 2 (liprin beta 2) |
| PPP4R4 | protein phosphatase 4, regulatory subunit 4 |
| PTK2B | protein tyrosine kinase 2 beta |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 |
| RARA | retinoic acid receptor, alpha |
| RARB | retinoic acid receptor, beta |
| RGS4 | regulator of G-protein signaling 4 |
| RGS5 | regulator of G-protein signaling 5 |
| RIMS2 | regulating synaptic membrane exocytosis 2 |
| RND1 | Rho family GTPase 1 |
| SAFB | scaffold attachment factor B |
| SBNO1 | strawberry notch homolog 1 (Drosophila) |
| SEMA3D | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D |
| SETD1A | SET domain containing 1A |
| SKP2 | S-phase kinase-associated protein 2, E3 ubiquitin protein ligase |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 |
| SMARCA2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 |
| SPPL2B | signal peptide peptidase like 2B |
| SUGP1 | SURP and G patch domain containing 1 |
| SWAP70 | SWAP switching B-cell complex 70kDa subunit |
| TACSTD2 | tumor-associated calcium signal transducer 2 |
| TBXA2R | thromboxane A2 receptor |
| TCP11L1 | t-complex 11, testis-specific-like 1 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) |
| TGM4 | transglutaminase 4 |
| VNN2 | vanin 2 |
| VPRBP | Vpr (HIV-1) binding protein |
| VPS53 | vacuolar protein sorting 53 homolog (S. cerevisiae) |
| ZNF225 | zinc finger protein 225 |
| ZNF79 | zinc finger protein 79 |
| Symbol | Name |
|---|---|
| ABCC2 | ATP-binding cassette, sub-family C (CFTR/MRP), member 2 |
| ADAM2 | ADAM metallopeptidase domain 2 |
| ALOX12 | arachidonate 12-lipoxygenase |
| APOC4 | apolipoprotein C-IV |
| ARHGAP24 | Rho GTPase activating protein 24 |
| BFSP1 | beaded filament structural protein 1, filensin |
| BTF3P12 | basic transcription factor 3 pseudogene 12 |
| C14ORF105 | chromosome 14 open reading frame 105 |
| C7ORF69 | chromosome 7 open reading frame 69 |
| CA9 | carbonic anhydrase IX |
| CAPN15 | calpain 15 |
| CASP5 | caspase 5, apoptosis-related cysteine peptidase |
| CCL2 | chemokine (C-C motif) ligand 2 |
| CDHR2 | cadherin-related family member 2 |
| CLDN1 | claudin 1 |
| CNGB3 | cyclic nucleotide gated channel beta 3 |
| CNKSR1 | connector enhancer of kinase suppressor of Ras 1 |
| COMP | cartilage oligomeric matrix protein |
| CXCR2 | chemokine (C-X-C motif) receptor 2 |
| DGCR11 | DiGeorge syndrome critical region gene 11 (non-protein coding) |
| DGCR9 | DiGeorge syndrome critical region gene 9 (non-protein coding) |
| DOK5 | docking protein 5 |
| ELP6 | elongator acetyltransferase complex subunit 6 |
| ENTPD5 | ectonucleoside triphosphate diphosphohydrolase 5 |
| EYA3 | EYA transcriptional coactivator and phosphatase 3 |
| FKBP5 | FK506 binding protein 5 |
| FLT4 | fms-related tyrosine kinase 4 |
| FRMPD1 | FERM and PDZ domain containing 1 |
| FURIN | furin (paired basic amino acid cleaving enzyme) |
| GABRA2 | gamma-aminobutyric acid (GABA) A receptor, alpha 2 |
| GABRP | gamma-aminobutyric acid (GABA) A receptor, pi |
| GNA14 | guanine nucleotide binding protein (G protein), alpha 14 |
| GRM4 | glutamate receptor, metabotropic 4 |
| GTF3C5 | general transcription factor IIIC, polypeptide 5, 63kDa |
| GUCY1B2 | guanylate cyclase 1, soluble, beta 2 (pseudogene) |
| H1F0 | H1 histone family, member 0 |
| HAMP | hepcidin antimicrobial peptide |
| HESX1 | HESX homeobox 1 |
| HIST1H2BN | histone cluster 1, H2bn |
| HPR | haptoglobin-related protein |
| IL36RN | interleukin 36 receptor antagonist |
| KCNN1 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1 |
| KDM5C | lysine (K)-specific demethylase 5C |
| KLF13 | Kruppel-like factor 13 |
| KLHL28 | kelch-like family member 28 |
| LAX1 | lymphocyte transmembrane adaptor 1 |
| LIME1 | Lck interacting transmembrane adaptor 1 |
| LPAR4 | lysophosphatidic acid receptor 4 |
| LRP3 | low density lipoprotein receptor-related protein 3 |
| LTC4S | leukotriene C4 synthase |
| LYL1 | lymphoblastic leukemia associated hematopoiesis regulator 1 |
| MBL1P | mannose-binding lectin (protein A) 1, pseudogene |
| MXRA8 | matrix-remodelling associated 8 |
| MYL9 | myosin, light chain 9, regulatory |
| MYO15A | myosin XVA |
| NT5DC3 | 5'-nucleotidase domain containing 3 |
| OR10H1 | olfactory receptor, family 10, subfamily H, member 1 |
| OSBP2 | oxysterol binding protein 2 |
| PALM | paralemmin |
| PDE6C | phosphodiesterase 6C, cGMP-specific, cone, alpha prime |
| PEX26 | peroxisomal biogenesis factor 26 |
| PLBD1 | phospholipase B domain containing 1 |
| PLEKHG6 | pleckstrin homology domain containing, family G (with RhoGef domain) member 6 |
| PLEKHO1 | pleckstrin homology domain containing, family O member 1 |
| PODNL1 | podocan-like 1 |
| PPP2R3B | protein phosphatase 2, regulatory subunit B'', beta |
| PRB3 | proline-rich protein BstNI subfamily 3 |
| PRICKLE3 | prickle homolog 3 (Drosophila) |
| PRM2 | protamine 2 |
| PRR15L | proline rich 15-like |
| PRR4 | proline rich 4 (lacrimal) |
| PRR7 | proline rich 7 (synaptic) |
| RAPGEFL1 | Rap guanine nucleotide exchange factor (GEF)-like 1 |
| RAPSN | receptor-associated protein of the synapse |
| REM1 | RAS (RAD and GEM)-like GTP-binding 1 |
| RGCC | regulator of cell cycle |
| RGP1 | RGP1 retrograde golgi transport homolog (S. cerevisiae) |
| S100A3 | S100 calcium binding protein A3 |
| SBNO2 | strawberry notch homolog 2 (Drosophila) |
| SCD5 | stearoyl-CoA desaturase 5 |
| SDC3 | syndecan 3 |
| SLC16A6 | solute carrier family 16, member 6 |
| SLC5A2 | solute carrier family 5 (sodium/glucose cotransporter), member 2 |
| SMR3A | submaxillary gland androgen regulated protein 3A |
| SOX12 | SRY (sex determining region Y)-box 12 |
| SSBP3 | single stranded DNA binding protein 3 |
| STAB2 | stabilin 2 |
| TAB1 | TGF-beta activated kinase 1/MAP3K7 binding protein 1 |
| TBC1D22B | TBC1 domain family, member 22B |
| TBKBP1 | TBK1 binding protein 1 |
| TEAD3 | TEA domain family member 3 |
| TESPA1 | thymocyte expressed, positive selection associated 1 |
| TFAP4 | transcription factor AP-4 (activating enhancer binding protein 4) |
| TIGD6 | tigger transposable element derived 6 |
| TLN1 | talin 1 |
| TRPV6 | transient receptor potential cation channel, subfamily V, member 6 |
| WDR25 | WD repeat domain 25 |
| WNT1 | wingless-type MMTV integration site family, member 1 |
| ZFHX3 | zinc finger homeobox 3 |
