| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the seneciphylline-4822 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AGO4 | argonaute RISC catalytic component 4 |
| AKR1B1 | aldo-keto reductase family 1, member B1 (aldose reductase) |
| ANK1 | ankyrin 1, erythrocytic |
| BTF3P11 | basic transcription factor 3 pseudogene 11 |
| BUB1 | BUB1 mitotic checkpoint serine/threonine kinase |
| C22ORF46 | chromosome 22 open reading frame 46 |
| CACNA1H | calcium channel, voltage-dependent, T type, alpha 1H subunit |
| CALD1 | caldesmon 1 |
| CARTPT | CART prepropeptide |
| CBX8 | chromobox homolog 8 |
| CD244 | CD244 molecule, natural killer cell receptor 2B4 |
| CD68 | CD68 molecule |
| CEACAM3 | carcinoembryonic antigen-related cell adhesion molecule 3 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 |
| CES3 | carboxylesterase 3 |
| CFTR | cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) |
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) |
| CHRNB2 | cholinergic receptor, nicotinic, beta 2 (neuronal) |
| CMA1 | chymase 1, mast cell |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 |
| COMMD4 | COMM domain containing 4 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa |
| CYP27A1 | cytochrome P450, family 27, subfamily A, polypeptide 1 |
| CYP3A4 | cytochrome P450, family 3, subfamily A, polypeptide 4 |
| EN2 | engrailed homeobox 2 |
| FGF1 | fibroblast growth factor 1 (acidic) |
| FRMD4B | FERM domain containing 4B |
| FSCN3 | fascin actin-bundling protein 3, testicular |
| FXYD5 | FXYD domain containing ion transport regulator 5 |
| FZD9 | frizzled class receptor 9 |
| GAMT | guanidinoacetate N-methyltransferase |
| GJB3 | gap junction protein, beta 3, 31kDa |
| GNG13 | guanine nucleotide binding protein (G protein), gamma 13 |
| GOLGA2P5 | golgin A2 pseudogene 5 |
| GPR161 | G protein-coupled receptor 161 |
| GRIN2C | glutamate receptor, ionotropic, N-methyl D-aspartate 2C |
| GSTA3 | glutathione S-transferase alpha 3 |
| GSTP1 | glutathione S-transferase pi 1 |
| HGFAC | HGF activator |
| HIST1H1E | histone cluster 1, H1e |
| HOXA4 | homeobox A4 |
| HOXA7 | homeobox A7 |
| HOXC8 | homeobox C8 |
| IBSP | integrin-binding sialoprotein |
| IFI6 | interferon, alpha-inducible protein 6 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
| IGFBP5 | insulin-like growth factor binding protein 5 |
| IGHM | immunoglobulin heavy constant mu |
| IGLJ3 | immunoglobulin lambda joining 3 |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) |
| JMJD6 | jumonji domain containing 6 |
| JPH3 | junctophilin 3 |
| KPNA5 | karyopherin alpha 5 (importin alpha 6) |
| KSR1 | kinase suppressor of ras 1 |
| LAMA4 | laminin, alpha 4 |
| LCT | lactase |
| LIF | leukemia inhibitory factor |
| LILRB3 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 |
| LOC100286895 | cell division cycle 27 homolog pseudogene |
| MAF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog |
| MAPK7 | mitogen-activated protein kinase 7 |
| MAPK8IP2 | mitogen-activated protein kinase 8 interacting protein 2 |
| MED25 | mediator complex subunit 25 |
| MEF2D | myocyte enhancer factor 2D |
| MTRF1L | mitochondrial translational release factor 1-like |
| MYEF2 | myelin expression factor 2 |
| MYL4 | myosin, light chain 4, alkali; atrial, embryonic |
| MYLPF | myosin light chain, phosphorylatable, fast skeletal muscle |
| N4BP2L2-IT2 | N4BPL2 intronic transcript 2 |
| OASL | 2'-5'-oligoadenylate synthetase-like |
| OR2B6 | olfactory receptor, family 2, subfamily B, member 6 |
| OVOL2 | ovo-like zinc finger 2 |
| PCDHGA10 | protocadherin gamma subfamily A, 10 |
| PDGFRA | platelet-derived growth factor receptor, alpha polypeptide |
| PILRA | paired immunoglobin-like type 2 receptor alpha |
| POU2F3 | POU class 2 homeobox 3 |
| PRB3 | proline-rich protein BstNI subfamily 3 |
| PTGER3 | prostaglandin E receptor 3 (subtype EP3) |
| PTPRB | protein tyrosine phosphatase, receptor type, B |
| PURG | purine-rich element binding protein G |
| RGS1 | regulator of G-protein signaling 1 |
| RORC | RAR-related orphan receptor C |
| RQCD1 | RCD1 required for cell differentiation1 homolog (S. pombe) |
| RTEL1 | regulator of telomere elongation helicase 1 |
| RUNX1 | runt-related transcription factor 1 |
| SLC25A30 | solute carrier family 25, member 30 |
| SLC6A13 | solute carrier family 6 (neurotransmitter transporter), member 13 |
| SLC7A8 | solute carrier family 7 (amino acid transporter light chain, L system), member 8 |
| SPTBN2 | spectrin, beta, non-erythrocytic 2 |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase |
| SRD5A2 | steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2) |
| SSX3 | synovial sarcoma, X breakpoint 3 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 |
| TPMT | thiopurine S-methyltransferase |
| WDR76 | WD repeat domain 76 |
| WNT1 | wingless-type MMTV integration site family, member 1 |
| WT1-AS | WT1 antisense RNA |
| Symbol | Name |
|---|---|
| AGPAT5 | 1-acylglycerol-3-phosphate O-acyltransferase 5 |
| AP1AR | adaptor-related protein complex 1 associated regulatory protein |
| APPL1 | adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1 |
| APPL2 | adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2 |
| ARHGAP12 | Rho GTPase activating protein 12 |
| ASB7 | ankyrin repeat and SOCS box containing 7 |
| ATAD5 | ATPase family, AAA domain containing 5 |
| ATP8B2 | ATPase, aminophospholipid transporter, class I, type 8B, member 2 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 |
| C1GALT1C1 | C1GALT1-specific chaperone 1 |
| CBLL1 | Cbl proto-oncogene-like 1, E3 ubiquitin protein ligase |
| CDC50A | cell division cycle 50 P4-ATPase accessory subunit A |
| CDC73 | cell division cycle 73 |
| CEP70 | centrosomal protein 70kDa |
| CHUK | conserved helix-loop-helix ubiquitous kinase |
| CLDN15 | claudin 15 |
| CLDND1 | claudin domain containing 1 |
| CLUHP3 | clustered mitochondria (cluA/CLU1) homolog pseudogene 3 |
| CMAS | cytidine monophosphate N-acetylneuraminic acid synthetase |
| COCH | cochlin |
| COPS5 | COP9 signalosome subunit 5 |
| CRABP1 | cellular retinoic acid binding protein 1 |
| CRADD | CASP2 and RIPK1 domain containing adaptor with death domain |
| CRYZL1 | crystallin, zeta (quinone reductase)-like 1 |
| CTNNBIP1 | catenin, beta interacting protein 1 |
| DCAF17 | DDB1 and CUL4 associated factor 17 |
| DENND4C | DENN/MADD domain containing 4C |
| DHX57 | DEAH (Asp-Glu-Ala-Asp/His) box polypeptide 57 |
| DNA2 | DNA replication helicase/nuclease 2 |
| DNAJA2 | DnaJ (Hsp40) homolog, subfamily A, member 2 |
| DNAJC24 | DnaJ (Hsp40) homolog, subfamily C, member 24 |
| DTWD1 | DTW domain containing 1 |
| ECHDC1 | ethylmalonyl-CoA decarboxylase 1 |
| EMC2 | ER membrane protein complex subunit 2 |
| ETAA1 | Ewing tumor-associated antigen 1 |
| FAIM | Fas apoptotic inhibitory molecule |
| FBXO5 | F-box protein 5 |
| FZD6 | frizzled class receptor 6 |
| GATC | glutamyl-tRNA(Gln) amidotransferase, subunit C |
| HCFC2 | host cell factor C2 |
| HEATR3 | HEAT repeat containing 3 |
| HIRA | histone cell cycle regulator |
| IMPACT | impact RWD domain protein |
| IMPAD1 | inositol monophosphatase domain containing 1 |
| KCTD9 | potassium channel tetramerization domain containing 9 |
| KIAA0895 | KIAA0895 |
| KIF14 | kinesin family member 14 |
| LMCD1 | LIM and cysteine-rich domains 1 |
| LOC257152 | uncharacterized LOC257152 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 |
| LRIG1 | leucine-rich repeats and immunoglobulin-like domains 1 |
| MED4 | mediator complex subunit 4 |
| MOCS2 | molybdenum cofactor synthesis 2 |
| MORC3 | MORC family CW-type zinc finger 3 |
| MTCL1 | microtubule crosslinking factor 1 |
| MYBL1 | v-myb avian myeloblastosis viral oncogene homolog-like 1 |
| NAA50 | N(alpha)-acetyltransferase 50, NatE catalytic subunit |
| NECAP1 | NECAP endocytosis associated 1 |
| NLK | nemo-like kinase |
| NNT | nicotinamide nucleotide transhydrogenase |
| NR1D2 | nuclear receptor subfamily 1, group D, member 2 |
| OSGEPL1 | O-sialoglycoprotein endopeptidase-like 1 |
| PANX1 | pannexin 1 |
| PCMTD2 | protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2 |
| PCNXL4 | pecanex-like 4 (Drosophila) |
| PGGT1B | protein geranylgeranyltransferase type I, beta subunit |
| PIM2 | Pim-2 proto-oncogene, serine/threonine kinase |
| PRMT3 | protein arginine methyltransferase 3 |
| PRSS16 | protease, serine, 16 (thymus) |
| PTPN13 | protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) |
| RAD51AP1 | RAD51 associated protein 1 |
| RNF11 | ring finger protein 11 |
| RNF146 | ring finger protein 146 |
| RNF38 | ring finger protein 38 |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A |
| SENP2 | SUMO1/sentrin/SMT3 specific peptidase 2 |
| SKA1 | spindle and kinetochore associated complex subunit 1 |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 |
| SMU1 | smu-1 suppressor of mec-8 and unc-52 homolog (C. elegans) |
| SNIP1 | Smad nuclear interacting protein 1 |
| STXBP3 | syntaxin binding protein 3 |
| SYTL2 | synaptotagmin-like 2 |
| TGDS | TDP-glucose 4,6-dehydratase |
| TRAPPC13 | trafficking protein particle complex 13 |
| TRAPPC2 | trafficking protein particle complex 2 |
| TRIM5 | tripartite motif containing 5 |
| TRMT13 | tRNA methyltransferase 13 homolog (S. cerevisiae) |
| TRMT2A | tRNA methyltransferase 2 homolog A (S. cerevisiae) |
| TRMU | tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase |
| TTC17 | tetratricopeptide repeat domain 17 |
| USP6NL | USP6 N-terminal like |
| VCPKMT | valosin containing protein lysine (K) methyltransferase |
| YIPF5 | Yip1 domain family, member 5 |
| YRDC | yrdC N(6)-threonylcarbamoyltransferase domain containing |
| ZNF430 | zinc finger protein 430 |
| ZNF586 | zinc finger protein 586 |
| ZNF654 | zinc finger protein 654 |
| ZNF816 | zinc finger protein 816 |
| ZSCAN16 | zinc finger and SCAN domain containing 16 |
| ZSCAN26 | zinc finger and SCAN domain containing 26 |
