senescence-associated heterochromatin focus assembly Gene Set

Dataset GO Biological Process Annotations
Category structural or functional annotations
Type biological process
Description The assembly of chromatin into senescence-associated heterochromatin foci (SAHF), transcriptionally-silent heterochromatin structures present in senescent cells, containing the condensed chromatin of one chromosome, and enriched for histone modifications. Formation of these chromatin structures is thought to repress expression of proliferation-promoting genes. (Gene Ontology, GO_0035986)
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3 genes participating in the senescence-associated heterochromatin focus assembly biological process from the curated GO Biological Process Annotations dataset.

Symbol Name
CDKN2A cyclin-dependent kinase inhibitor 2A
HMGA1 high mobility group AT-hook 1
HMGA2 high mobility group AT-hook 2