senescence-associated heterochromatin focus Gene Set

Dataset GO Cellular Component Annotations
Category structural or functional annotations
Type cellular component
Description A transcriptionally-silent heterochromatin structure present in senescent cells. Contains the condensed chromatin of one chromosome and is enriched for histone modifications. Thought to repress expression of proliferation-promoting genes. (Gene Ontology, GO_0035985)
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3 proteins localized to the senescence-associated heterochromatin focus cellular component from the curated GO Cellular Component Annotations dataset.

Symbol Name
CDKN2A cyclin-dependent kinase inhibitor 2A
HMGA1 high mobility group AT-hook 1
HMGA2 high mobility group AT-hook 2