senescent Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
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Genes

103 genes co-occuring with the biological term senescent in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ADAM17 ADAM metallopeptidase domain 17
AKAP12 A kinase (PRKA) anchor protein 12
APP amyloid beta (A4) precursor protein
AR androgen receptor
ASF1A anti-silencing function 1A histone chaperone
BCL2 B-cell CLL/lymphoma 2
BCL2L1 BCL2-like 1
BMI1 BMI1 proto-oncogene, polycomb ring finger
BTG2 BTG family, member 2
CABIN1 calcineurin binding protein 1
CAV1 caveolin 1, caveolae protein, 22kDa
CCL2 chemokine (C-C motif) ligand 2
CCND1 cyclin D1
CCR2 chemokine (C-C motif) receptor 2
CD44 CD44 molecule (Indian blood group)
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CDKN2A cyclin-dependent kinase inhibitor 2A
CRTC1 CREB regulated transcription coactivator 1
CX3CL1 chemokine (C-X3-C motif) ligand 1
DNM1L dynamin 1-like
E2F1 E2F transcription factor 1
EGFR epidermal growth factor receptor
EPHA2 EPH receptor A2
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FAS Fas cell surface death receptor
FCGR3A Fc fragment of IgG, low affinity IIIa, receptor (CD16a)
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)
GADD45A growth arrest and DNA-damage-inducible, alpha
GSK3B glycogen synthase kinase 3 beta
GSN gelsolin
HAVCR2 hepatitis A virus cellular receptor 2
HELLS helicase, lymphoid-specific
HIRA histone cell cycle regulator
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HSPA8 heat shock 70kDa protein 8
HSPD1 heat shock 60kDa protein 1 (chaperonin)
IGF1R insulin-like growth factor 1 receptor
IGF2 insulin-like growth factor 2
IGFBP3 insulin-like growth factor binding protein 3
IGFBP7 insulin-like growth factor binding protein 7
IL10 interleukin 10
IL20 interleukin 20
IL24 interleukin 24
IL6 interleukin 6
ING1 inhibitor of growth family, member 1
JAK1 Janus kinase 1
KDM5A lysine (K)-specific demethylase 5A
KDM5B lysine (K)-specific demethylase 5B
KL klotho
LMNA lamin A/C
LMNB1 lamin B1
MAPK14 mitogen-activated protein kinase 14
MIR146A microRNA 146a
MIR152 microRNA 152
MIR93 microRNA 93
MSH2 mutS homolog 2
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MVP major vault protein
MYC v-myc avian myelocytomatosis viral oncogene homolog
NOX4 NADPH oxidase 4
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin)
NUTF2 nuclear transport factor 2
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor)
PINK1 PTEN induced putative kinase 1
PML promyelocytic leukemia
PPM1D protein phosphatase, Mg2+/Mn2+ dependent, 1D
PRKAB1 protein kinase, AMP-activated, beta 1 non-catalytic subunit
PRKCD protein kinase C, delta
PSAP prosaposin
PTEN phosphatase and tensin homolog
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTK2 protein tyrosine kinase 2
PTRF polymerase I and transcript release factor
RAN RAN, member RAS oncogene family
RB1 retinoblastoma 1
RRM2B ribonucleotide reductase M2 B (TP53 inducible)
S1PR2 sphingosine-1-phosphate receptor 2
SEN6A senescence (cellular)-related 6A
SIRT1 sirtuin 1
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
SLC4A1 solute carrier family 4 (anion exchanger), member 1 (Diego blood group)
SRC SRC proto-oncogene, non-receptor tyrosine kinase
SRF serum response factor (c-fos serum response element-binding transcription factor)
STAT1 signal transducer and activator of transcription 1, 91kDa
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
TEAD1 TEA domain family member 1 (SV40 transcriptional enhancer factor)
TEAD3 TEA domain family member 3
TEAD4 TEA domain family member 4
TERT telomerase reverse transcriptase
TP53 tumor protein p53
TXN thioredoxin
UBN1 ubinuclein 1
VCAM1 vascular cell adhesion molecule 1
VEGFA vascular endothelial growth factor A
WFDC1 WAP four-disulfide core domain 1
WRN Werner syndrome, RecQ helicase-like
XPO6 exportin 6
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6
YAP1 Yes-associated protein 1
ZMPSTE24 zinc metallopeptidase STE24