sensitization Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description An increased in a behavioral response to a repeated stimulus. For example, a shock to the tail of the marine snail Aplysia, to which the snail responds by withdrawing its gill, will result in increased gill withdrawal the next time the skin is touched. (Gene Ontology, GO_0046960)
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Genes

165 genes co-occuring with the biological term sensitization in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
ACE angiotensin I converting enzyme
ADAM33 ADAM metallopeptidase domain 33
ADCY1 adenylate cyclase 1 (brain)
ADCY2 adenylate cyclase 2 (brain)
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
ADRB2 adrenoceptor beta 2, surface
ADRBK1 adrenergic, beta, receptor kinase 1
ANXA2 annexin A2
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1
ARHGEF11 Rho guanine nucleotide exchange factor (GEF) 11
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12
ASIC3 acid sensing (proton gated) ion channel 3
BAD BCL2-associated agonist of cell death
BAK1 BCL2-antagonist/killer 1
BAX BCL2-associated X protein
BBC3 BCL2 binding component 3
BCL2 B-cell CLL/lymphoma 2
BCL2L11 BCL2-like 11 (apoptosis facilitator)
BDNF brain-derived neurotrophic factor
BIK BCL2-interacting killer (apoptosis-inducing)
BIRC5 baculoviral IAP repeat containing 5
BRAF B-Raf proto-oncogene, serine/threonine kinase
BRCA1 breast cancer 1, early onset
BRCA2 breast cancer 2, early onset
CAMK2A calcium/calmodulin-dependent protein kinase II alpha
CASP2 caspase 2, apoptosis-related cysteine peptidase
CCL22 chemokine (C-C motif) ligand 22
CCL5 chemokine (C-C motif) ligand 5
CD209 CD209 molecule
CDK4 cyclin-dependent kinase 4
CDK5 cyclin-dependent kinase 5
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CHEK1 checkpoint kinase 1
CHRNA5 cholinergic receptor, nicotinic, alpha 5 (neuronal)
CLDN1 claudin 1
CNR1 cannabinoid receptor 1 (brain)
COMT catechol-O-methyltransferase
CRP C-reactive protein, pentraxin-related
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1
DEFB4A defensin, beta 4A
DISC1 disrupted in schizophrenia 1
DNASE1L3 deoxyribonuclease I-like 3
DOCK8 dedicator of cytokinesis 8
DRD2 dopamine receptor D2
DSG1 desmoglein 1
DUT deoxyuridine triphosphatase
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
EP300 E1A binding protein p300
ERBB2 erb-b2 receptor tyrosine kinase 2
F2RL1 coagulation factor II (thrombin) receptor-like 1
FAS Fas cell surface death receptor
FCER1G Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide
FES FES proto-oncogene, tyrosine kinase
FKBP5 FK506 binding protein 5
FLG filaggrin
FOXO1 forkhead box O1
GNAS GNAS complex locus
GRIN1 glutamate receptor, ionotropic, N-methyl D-aspartate 1
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B
GSTT1 glutathione S-transferase theta 1
HBA1 hemoglobin, alpha 1
HDAC5 histone deacetylase 5
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HLA-A major histocompatibility complex, class I, A
HLA-B major histocompatibility complex, class I, B
HLA-DPB1 major histocompatibility complex, class II, DP beta 1
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HRAS Harvey rat sarcoma viral oncogene homolog
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
HSPB2 heat shock 27kDa protein 2
ICOS inducible T-cell co-stimulator
IFNG interferon, gamma
IL10 interleukin 10
IL12RB1 interleukin 12 receptor, beta 1
IL13 interleukin 13
IL16 interleukin 16
IL18 interleukin 18
IL1A interleukin 1, alpha
IL1R1 interleukin 1 receptor, type I
IL22 interleukin 22
IL4 interleukin 4
IL9 interleukin 9
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3
JUN jun proto-oncogene
KCNC4 potassium channel, voltage gated Shaw related subfamily C, member 4
KMT2A lysine (K)-specific methyltransferase 2A
KRAS Kirsten rat sarcoma viral oncogene homolog
LRP1 low density lipoprotein receptor-related protein 1
MAP2K7 mitogen-activated protein kinase kinase 7
MAPK1 mitogen-activated protein kinase 1
MAPK14 mitogen-activated protein kinase 14
MCL1 myeloid cell leukemia 1
MGMT O-6-methylguanine-DNA methyltransferase
MICA MHC class I polypeptide-related sequence A
MICU1 mitochondrial calcium uptake 1
MIR449A microRNA 449a
MMP9 matrix metallopeptidase 9
MS4A2 membrane-spanning 4-domains, subfamily A, member 2
MTOR mechanistic target of rapamycin (serine/threonine kinase)
NBN nibrin
NFE2L2 nuclear factor, erythroid 2-like 2
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NGF nerve growth factor (beta polypeptide)
NGFG Nerve growth factor, gamma subunit
NLRP3 NLR family, pyrin domain containing 3
NPSR1 neuropeptide S receptor 1
NTRK1 neurotrophic tyrosine kinase, receptor, type 1
P2RX3 purinergic receptor P2X, ligand gated ion channel, 3
PIDD1 p53-induced death domain protein 1
PIEZO2 piezo-type mechanosensitive ion channel component 2
PPARG peroxisome proliferator-activated receptor gamma
PPP1R12A protein phosphatase 1, regulatory subunit 12A
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit
PSMB5 proteasome (prosome, macropain) subunit, beta type, 5
PTEN phosphatase and tensin homolog
PTGDR2 prostaglandin D2 receptor 2
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTPN6 protein tyrosine phosphatase, non-receptor type 6
QSOX2 quiescin Q6 sulfhydryl oxidase 2
RAB4A RAB4A, member RAS oncogene family
RGS5 regulator of G-protein signaling 5
RHD Rh blood group, D antigen
RHOA ras homolog family member A
RNASE2 ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin)
ROCK1 Rho-associated, coiled-coil containing protein kinase 1
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1
RYR1 ryanodine receptor 1 (skeletal)
SDHC succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa
SIRT1 sirtuin 1
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4
STAT1 signal transducer and activator of transcription 1, 91kDa
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced
TERT telomerase reverse transcriptase
TLR2 toll-like receptor 2
TLR4 toll-like receptor 4
TLR9 toll-like receptor 9
TNC tenascin C
TNF tumor necrosis factor
TNFRSF10A tumor necrosis factor receptor superfamily, member 10a
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TP53 tumor protein p53
TP73 tumor protein p73
TRPA1 transient receptor potential cation channel, subfamily A, member 1
TRPM8 transient receptor potential cation channel, subfamily M, member 8
TRPV1 transient receptor potential cation channel, subfamily V, member 1
TRPV3 transient receptor potential cation channel, subfamily V, member 3
TRPV4 transient receptor potential cation channel, subfamily V, member 4
TSLP thymic stromal lymphopoietin
TSPYL5 TSPY-like 5
TTC5 tetratricopeptide repeat domain 5
TWIST1 twist family bHLH transcription factor 1
UBE2C ubiquitin-conjugating enzyme E2C
USP28 ubiquitin specific peptidase 28
VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase
WEE1 WEE1 G2 checkpoint kinase
XAF1 XIAP associated factor 1
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6
YBX1 Y box binding protein 1
YY1 YY1 transcription factor