sepsis; systemic infection Gene Set
Genes
28 genes associated with the disease sepsis; systemic infection in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.
| Symbol |
Name |
|
ACE
|
angiotensin I converting enzyme
|
|
APOE
|
apolipoprotein E
|
|
BPI
|
bactericidal/permeability-increasing protein
|
|
CD14
|
CD14 molecule
|
|
CXCL2
|
chemokine (C-X-C motif) ligand 2
|
|
CXCL8
|
chemokine (C-X-C motif) ligand 8
|
|
DEFA1
|
defensin, alpha 1
|
|
DEFA3
|
defensin, alpha 3, neutrophil-specific
|
|
F5
|
coagulation factor V (proaccelerin, labile factor)
|
|
IL10
|
interleukin 10
|
|
IL10RA
|
interleukin 10 receptor, alpha
|
|
IL18
|
interleukin 18
|
|
IL1B
|
interleukin 1, beta
|
|
IL1RN
|
interleukin 1 receptor antagonist
|
|
IL4R
|
interleukin 4 receptor
|
|
IL6
|
interleukin 6
|
|
IRAK1
|
interleukin-1 receptor-associated kinase 1
|
|
LTA
|
lymphotoxin alpha
|
|
MBL2
|
mannose-binding lectin (protein C) 2, soluble
|
|
MYD88
|
myeloid differentiation primary response 88
|
|
NOD2
|
nucleotide-binding oligomerization domain containing 2
|
|
NOS3
|
nitric oxide synthase 3 (endothelial cell)
|
|
PLA2G2A
|
phospholipase A2, group IIA (platelets, synovial fluid)
|
|
TLR1
|
toll-like receptor 1
|
|
TLR2
|
toll-like receptor 2
|
|
TLR4
|
toll-like receptor 4
|
|
TLR5
|
toll-like receptor 5
|
|
TNF
|
tumor necrosis factor
|
