| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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196 genes differentially expressed following the serotonin-2449 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACADS | acyl-CoA dehydrogenase, C-2 to C-3 short chain |
| AIF1 | allograft inflammatory factor 1 |
| ALG12 | ALG12, alpha-1,6-mannosyltransferase |
| ANGPTL2 | angiopoietin-like 2 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 |
| APOE | apolipoprotein E |
| AR | androgen receptor |
| ARHGAP32 | Rho GTPase activating protein 32 |
| ARHGAP44 | Rho GTPase activating protein 44 |
| ARRB1 | arrestin, beta 1 |
| ASPH | aspartate beta-hydroxylase |
| ATP13A2 | ATPase type 13A2 |
| ATP2A3 | ATPase, Ca++ transporting, ubiquitous |
| ATP6V1C1 | ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1 |
| AURKA | aurora kinase A |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A |
| BEND5 | BEN domain containing 5 |
| BMP8A | bone morphogenetic protein 8a |
| BRF1 | BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit |
| BUB1 | BUB1 mitotic checkpoint serine/threonine kinase |
| CACNB1 | calcium channel, voltage-dependent, beta 1 subunit |
| CAMSAP2 | calmodulin regulated spectrin-associated protein family, member 2 |
| CASP10 | caspase 10, apoptosis-related cysteine peptidase |
| CCNK | cyclin K |
| CD59 | CD59 molecule, complement regulatory protein |
| CDC25C | cell division cycle 25C |
| CDRT1 | CMT1A duplicated region transcript 1 |
| CHM | choroideremia (Rab escort protein 1) |
| DBNDD1 | dysbindin (dystrobrevin binding protein 1) domain containing 1 |
| DRD2 | dopamine receptor D2 |
| DSTYK | dual serine/threonine and tyrosine protein kinase |
| EFNA3 | ephrin-A3 |
| EIF1 | eukaryotic translation initiation factor 1 |
| ENTPD7 | ectonucleoside triphosphate diphosphohydrolase 7 |
| EXOC7 | exocyst complex component 7 |
| FANCA | Fanconi anemia, complementation group A |
| GJC1 | gap junction protein, gamma 1, 45kDa |
| HN1L | hematological and neurological expressed 1-like |
| HPX | hemopexin |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) |
| IL1RN | interleukin 1 receptor antagonist |
| INCENP | inner centromere protein antigens 135/155kDa |
| IQCK | IQ motif containing K |
| ITIH2 | inter-alpha-trypsin inhibitor heavy chain 2 |
| KAT8 | K(lysine) acetyltransferase 8 |
| KIAA0087 | KIAA0087 |
| KIAA1654 | KIAA1654 protein |
| KRT9 | keratin 9, type I |
| MAX | MYC associated factor X |
| MBP | myelin basic protein |
| MED25 | mediator complex subunit 25 |
| MLXIPL | MLX interacting protein-like |
| MRPS12 | mitochondrial ribosomal protein S12 |
| N4BP2L2-IT2 | N4BPL2 intronic transcript 2 |
| NDRG3 | NDRG family member 3 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase |
| NOX1 | NADPH oxidase 1 |
| NPC1 | Niemann-Pick disease, type C1 |
| NRF1 | nuclear respiratory factor 1 |
| NRP2 | neuropilin 2 |
| NUP214 | nucleoporin 214kDa |
| PCGF2 | polycomb group ring finger 2 |
| PDE4C | phosphodiesterase 4C, cAMP-specific |
| PDE4D | phosphodiesterase 4D, cAMP-specific |
| PDE4DIP | phosphodiesterase 4D interacting protein |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) |
| PLEKHF1 | pleckstrin homology domain containing, family F (with FYVE domain) member 1 |
| PROSC | proline synthetase co-transcribed homolog (bacterial) |
| PTGS1 | prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 |
| RAB3GAP2 | RAB3 GTPase activating protein subunit 2 (non-catalytic) |
| RAB6A | RAB6A, member RAS oncogene family |
| RND1 | Rho family GTPase 1 |
| SDS | serine dehydratase |
| SIX1 | SIX homeobox 1 |
| SLC16A5 | solute carrier family 16 (monocarboxylate transporter), member 5 |
| SLC35A2 | solute carrier family 35 (UDP-galactose transporter), member A2 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SMAD5 | SMAD family member 5 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 |
| SPAG8 | sperm associated antigen 8 |
| SPATA2L | spermatogenesis associated 2-like |
| SS18 | synovial sarcoma translocation, chromosome 18 |
| STAG3L4 | stromal antigen 3-like 4 (pseudogene) |
| STAT2 | signal transducer and activator of transcription 2, 113kDa |
| SULT1C2 | sulfotransferase family, cytosolic, 1C, member 2 |
| TBX6 | T-box 6 |
| THSD7A | thrombospondin, type I, domain containing 7A |
| TNC | tenascin C |
| TRBC1 | T cell receptor beta constant 1 |
| TRIM62 | tripartite motif containing 62 |
| TULP2 | tubby like protein 2 |
| VAMP2 | vesicle-associated membrane protein 2 (synaptobrevin 2) |
| ZBTB22 | zinc finger and BTB domain containing 22 |
| ZC3H7B | zinc finger CCCH-type containing 7B |
| ZNF174 | zinc finger protein 174 |
| ZNF667 | zinc finger protein 667 |
| ZNF675 | zinc finger protein 675 |
| Symbol | Name |
|---|---|
| ACPP | acid phosphatase, prostate |
| AMH | anti-Mullerian hormone |
| AOAH | acyloxyacyl hydrolase (neutrophil) |
| APOL6 | apolipoprotein L, 6 |
| ARHGEF3 | Rho guanine nucleotide exchange factor (GEF) 3 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) |
| ATHL1 | ATH1, acid trehalase-like 1 (yeast) |
| AXIN1 | axin 1 |
| BPHL | biphenyl hydrolase-like (serine hydrolase) |
| C16ORF59 | chromosome 16 open reading frame 59 |
| C9ORF9 | chromosome 9 open reading frame 9 |
| CCDC176 | coiled-coil domain containing 176 |
| CD79A | CD79a molecule, immunoglobulin-associated alpha |
| CHMP1A | charged multivesicular body protein 1A |
| CHST8 | carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8 |
| CNPY4 | canopy FGF signaling regulator 4 |
| COL15A1 | collagen, type XV, alpha 1 |
| CPNE7 | copine VII |
| CTSO | cathepsin O |
| DDX31 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 31 |
| DOK3 | docking protein 3 |
| DPEP2 | dipeptidase 2 |
| DSPP | dentin sialophosphoprotein |
| EMID1 | EMI domain containing 1 |
| EPHX1 | epoxide hydrolase 1, microsomal (xenobiotic) |
| ERCC6 | excision repair cross-complementation group 6 |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| EXO5 | exonuclease 5 |
| FCHO1 | FCH domain only 1 |
| FGF23 | fibroblast growth factor 23 |
| FGGY | FGGY carbohydrate kinase domain containing |
| FLT4 | fms-related tyrosine kinase 4 |
| G6PD | glucose-6-phosphate dehydrogenase |
| GABRA2 | gamma-aminobutyric acid (GABA) A receptor, alpha 2 |
| GATA6 | GATA binding protein 6 |
| GBF1 | golgi brefeldin A resistant guanine nucleotide exchange factor 1 |
| GJA8 | gap junction protein, alpha 8, 50kDa |
| GRIP2 | glutamate receptor interacting protein 2 |
| HAMP | hepcidin antimicrobial peptide |
| HIST1H2BN | histone cluster 1, H2bn |
| HP | haptoglobin |
| HPSE | heparanase |
| HTR2B | 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa |
| IL3RA | interleukin 3 receptor, alpha (low affinity) |
| IMPDH1 | IMP (inosine 5'-monophosphate) dehydrogenase 1 |
| KCTD7 | potassium channel tetramerization domain containing 7 |
| KLHL28 | kelch-like family member 28 |
| LINS | lines homolog (Drosophila) |
| LRFN4 | leucine rich repeat and fibronectin type III domain containing 4 |
| LRRC20 | leucine rich repeat containing 20 |
| MANSC1 | MANSC domain containing 1 |
| MAPKBP1 | mitogen-activated protein kinase binding protein 1 |
| MCOLN1 | mucolipin 1 |
| MRAS | muscle RAS oncogene homolog |
| MTERF1 | mitochondrial transcription termination factor 1 |
| MX2 | MX dynamin-like GTPase 2 |
| MYL5 | myosin, light chain 5, regulatory |
| NCKAP1L | NCK-associated protein 1-like |
| NEUROD4 | neuronal differentiation 4 |
| NIPAL2 | NIPA-like domain containing 2 |
| NXPH4 | neurexophilin 4 |
| OLFML2A | olfactomedin-like 2A |
| OXCT2 | 3-oxoacid CoA transferase 2 |
| P2RY11 | purinergic receptor P2Y, G-protein coupled, 11 |
| PAFAH1B2 | platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa) |
| PDGFRL | platelet-derived growth factor receptor-like |
| PDLIM2 | PDZ and LIM domain 2 (mystique) |
| PIM2 | Pim-2 proto-oncogene, serine/threonine kinase |
| PPP1R3C | protein phosphatase 1, regulatory subunit 3C |
| PTCD1 | pentatricopeptide repeat domain 1 |
| PTPRS | protein tyrosine phosphatase, receptor type, S |
| PVRL2 | poliovirus receptor-related 2 (herpesvirus entry mediator B) |
| RCAN3 | RCAN family member 3 |
| RNF2 | ring finger protein 2 |
| RPAP1 | RNA polymerase II associated protein 1 |
| RPP25 | ribonuclease P/MRP 25kDa subunit |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 |
| SLC25A23 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23 |
| SMYD5 | SMYD family member 5 |
| SNAI1 | snail family zinc finger 1 |
| SPATA1 | spermatogenesis associated 1 |
| STX11 | syntaxin 11 |
| TCTN2 | tectonic family member 2 |
| TIGD6 | tigger transposable element derived 6 |
| TMEM206 | transmembrane protein 206 |
| TRAF2 | TNF receptor-associated factor 2 |
| TRANK1 | tetratricopeptide repeat and ankyrin repeat containing 1 |
| TRPV1 | transient receptor potential cation channel, subfamily V, member 1 |
| TUBA3C | tubulin, alpha 3c |
| TUFT1 | tuftelin 1 |
| VEGFC | vascular endothelial growth factor C |
| VWA1 | von Willebrand factor A domain containing 1 |
| ZCWPW1 | zinc finger, CW type with PWWP domain 1 |
| ZNF493 | zinc finger protein 493 |
| ZNF701 | zinc finger protein 701 |
| ZNF862 | zinc finger protein 862 |
