| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the serotonin-3311 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADAM2 | ADAM metallopeptidase domain 2 |
| ADAM22 | ADAM metallopeptidase domain 22 |
| AGFG2 | ArfGAP with FG repeats 2 |
| ALMS1 | Alstrom syndrome protein 1 |
| APOE | apolipoprotein E |
| ARC | activity-regulated cytoskeleton-associated protein |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 |
| ASB1 | ankyrin repeat and SOCS box containing 1 |
| ATM | ATM serine/threonine kinase |
| ATP6V0A2 | ATPase, H+ transporting, lysosomal V0 subunit a2 |
| ATPAF2 | ATP synthase mitochondrial F1 complex assembly factor 2 |
| BBS9 | Bardet-Biedl syndrome 9 |
| CA5B | carbonic anhydrase VB, mitochondrial |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 |
| CCL19 | chemokine (C-C motif) ligand 19 |
| CFLAR | CASP8 and FADD-like apoptosis regulator |
| CNOT4 | CCR4-NOT transcription complex, subunit 4 |
| COX6A2 | cytochrome c oxidase subunit VIa polypeptide 2 |
| CUZD1 | CUB and zona pellucida-like domains 1 |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 |
| CYP2A7 | cytochrome P450, family 2, subfamily A, polypeptide 7 |
| CYTH4 | cytohesin 4 |
| DNAAF1 | dynein, axonemal, assembly factor 1 |
| DYNC1LI2 | dynein, cytoplasmic 1, light intermediate chain 2 |
| EGFR | epidermal growth factor receptor |
| EGR1 | early growth response 1 |
| ELSPBP1 | epididymal sperm binding protein 1 |
| ETV5 | ets variant 5 |
| FAM212B | family with sequence similarity 212, member B |
| FANCA | Fanconi anemia, complementation group A |
| FGF22 | fibroblast growth factor 22 |
| FN1 | fibronectin 1 |
| FOXN3 | forkhead box N3 |
| GNAT2 | guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2 |
| GNG4 | guanine nucleotide binding protein (G protein), gamma 4 |
| GOLGA8A | golgin A8 family, member A |
| GPC1 | glypican 1 |
| GRIP2 | glutamate receptor interacting protein 2 |
| GRM8 | glutamate receptor, metabotropic 8 |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HPSE2 | heparanase 2 (inactive) |
| HTR1B | 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled |
| ICOSLG | inducible T-cell co-stimulator ligand |
| IL17RC | interleukin 17 receptor C |
| IL6ST | interleukin 6 signal transducer |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 |
| KCNN1 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 1 |
| LATS1 | large tumor suppressor kinase 1 |
| LLPH | LLP homolog, long-term synaptic facilitation (Aplysia) |
| LSP1 | lymphocyte-specific protein 1 |
| MAPRE3 | microtubule-associated protein, RP/EB family, member 3 |
| MRPS12 | mitochondrial ribosomal protein S12 |
| MTHFR | methylenetetrahydrofolate reductase (NAD(P)H) |
| MTRF1L | mitochondrial translational release factor 1-like |
| NEK1 | NIMA-related kinase 1 |
| NPR1 | natriuretic peptide receptor 1 |
| NT5M | 5',3'-nucleotidase, mitochondrial |
| ONECUT2 | one cut homeobox 2 |
| PCDHA5 | protocadherin alpha 5 |
| PILRA | paired immunoglobin-like type 2 receptor alpha |
| PIM2 | Pim-2 proto-oncogene, serine/threonine kinase |
| PITX1 | paired-like homeodomain 1 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 |
| PRKCE | protein kinase C, epsilon |
| PTCRA | pre T-cell antigen receptor alpha |
| RAB3B | RAB3B, member RAS oncogene family |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 |
| RBFA | ribosome binding factor A (putative) |
| RBM5 | RNA binding motif protein 5 |
| RCBTB2 | regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 |
| REM1 | RAS (RAD and GEM)-like GTP-binding 1 |
| RGS14 | regulator of G-protein signaling 14 |
| RNFT1 | ring finger protein, transmembrane 1 |
| SIRT4 | sirtuin 4 |
| SKI | SKI proto-oncogene |
| SLC1A2 | solute carrier family 1 (glial high affinity glutamate transporter), member 2 |
| SLC22A17 | solute carrier family 22, member 17 |
| SLC4A4 | solute carrier family 4 (sodium bicarbonate cotransporter), member 4 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 |
| SPON1 | spondin 1, extracellular matrix protein |
| SPTLC2 | serine palmitoyltransferase, long chain base subunit 2 |
| SRP72 | signal recognition particle 72kDa |
| SSTR5 | somatostatin receptor 5 |
| STK17A | serine/threonine kinase 17a |
| SULT4A1 | sulfotransferase family 4A, member 1 |
| TFAP2A | transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha) |
| TIMM8A | translocase of inner mitochondrial membrane 8 homolog A (yeast) |
| TMEM63A | transmembrane protein 63A |
| TPP1 | tripeptidyl peptidase I |
| TUBBP5 | tubulin, beta pseudogene 5 |
| UGT8 | UDP glycosyltransferase 8 |
| UPK2 | uroplakin 2 |
| XRCC4 | X-ray repair complementing defective repair in Chinese hamster cells 4 |
| ZCCHC14 | zinc finger, CCHC domain containing 14 |
| ZNF34 | zinc finger protein 34 |
| ZNF589 | zinc finger protein 589 |
| ZZEF1 | zinc finger, ZZ-type with EF-hand domain 1 |
| Symbol | Name |
|---|---|
| A4GALT | alpha 1,4-galactosyltransferase |
| ACTL8 | actin-like 8 |
| ADM | adrenomedullin |
| ALS2CL | ALS2 C-terminal like |
| ASAP1-IT1 | ASAP1 intronic transcript 1 |
| C11ORF80 | chromosome 11 open reading frame 80 |
| C19ORF40 | chromosome 19 open reading frame 40 |
| CA5BP1 | carbonic anhydrase VB pseudogene 1 |
| CACNA1H | calcium channel, voltage-dependent, T type, alpha 1H subunit |
| CALML5 | calmodulin-like 5 |
| CAMK1 | calcium/calmodulin-dependent protein kinase I |
| CBX4 | chromobox homolog 4 |
| CBX7 | chromobox homolog 7 |
| CDK3 | cyclin-dependent kinase 3 |
| CHKB | choline kinase beta |
| CLCF1 | cardiotrophin-like cytokine factor 1 |
| COQ6 | coenzyme Q6 monooxygenase |
| CORT | cortistatin |
| CRY2 | cryptochrome circadian clock 2 |
| CRYBB2P1 | crystallin, beta B2 pseudogene 1 |
| CTC1 | CTS telomere maintenance complex component 1 |
| DCP1A | decapping mRNA 1A |
| ERCC6 | excision repair cross-complementation group 6 |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| FAM169A | family with sequence similarity 169, member A |
| FHOD1 | formin homology 2 domain containing 1 |
| FLCN | folliculin |
| FLVCR2 | feline leukemia virus subgroup C cellular receptor family, member 2 |
| FOXN2 | forkhead box N2 |
| FRK | fyn-related Src family tyrosine kinase |
| FURIN | furin (paired basic amino acid cleaving enzyme) |
| GCNT1 | glucosaminyl (N-acetyl) transferase 1, core 2 |
| GLS2 | glutaminase 2 (liver, mitochondrial) |
| GNG7 | guanine nucleotide binding protein (G protein), gamma 7 |
| GPR143 | G protein-coupled receptor 143 |
| HIST1H2AE | histone cluster 1, H2ae |
| HLA-DMA | major histocompatibility complex, class II, DM alpha |
| IFT140 | intraflagellar transport 140 |
| IL12RB1 | interleukin 12 receptor, beta 1 |
| IRF7 | interferon regulatory factor 7 |
| ITPKB | inositol-trisphosphate 3-kinase B |
| KDM7A | lysine (K)-specific demethylase 7A |
| KREMEN2 | kringle containing transmembrane protein 2 |
| LARP6 | La ribonucleoprotein domain family, member 6 |
| LRIG1 | leucine-rich repeats and immunoglobulin-like domains 1 |
| LY6D | lymphocyte antigen 6 complex, locus D |
| MAST3 | microtubule associated serine/threonine kinase 3 |
| MUL1 | mitochondrial E3 ubiquitin protein ligase 1 |
| NIPAL2 | NIPA-like domain containing 2 |
| NPIPB15 | nuclear pore complex interacting protein family, member B15 |
| NUP62CL | nucleoporin 62kDa C-terminal like |
| NUPL2 | nucleoporin like 2 |
| OTUB2 | OTU deubiquitinase, ubiquitin aldehyde binding 2 |
| PARPBP | PARP1 binding protein |
| PCDHB13 | protocadherin beta 13 |
| PCDHB8 | protocadherin beta 8 |
| PDPR | pyruvate dehydrogenase phosphatase regulatory subunit |
| PER3 | period circadian clock 3 |
| PIGQ | phosphatidylinositol glycan anchor biosynthesis, class Q |
| PIK3C2B | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta |
| PLCXD1 | phosphatidylinositol-specific phospholipase C, X domain containing 1 |
| PLEKHF1 | pleckstrin homology domain containing, family F (with FYVE domain) member 1 |
| PMEL | premelanosome protein |
| PREX2 | phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2 |
| PTDSS2 | phosphatidylserine synthase 2 |
| PTK6 | protein tyrosine kinase 6 |
| RIN2 | Ras and Rab interactor 2 |
| RNF39 | ring finger protein 39 |
| ROM1 | retinal outer segment membrane protein 1 |
| RSPH14 | radial spoke head 14 homolog (Chlamydomonas) |
| SGCG | sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein) |
| SIDT1 | SID1 transmembrane family, member 1 |
| SIRT6 | sirtuin 6 |
| SLC25A23 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23 |
| SP1 | Sp1 transcription factor |
| STARD3 | StAR-related lipid transfer (START) domain containing 3 |
| STX5 | syntaxin 5 |
| SYCP2 | synaptonemal complex protein 2 |
| TCTA | T-cell leukemia translocation altered |
| TESC | tescalcin |
| THBS3 | thrombospondin 3 |
| TM6SF1 | transmembrane 6 superfamily member 1 |
| TMC7 | transmembrane channel-like 7 |
| TMEM120B | transmembrane protein 120B |
| TMEM184C | transmembrane protein 184C |
| TMEM209 | transmembrane protein 209 |
| TMEM254 | transmembrane protein 254 |
| TMEM57 | transmembrane protein 57 |
| TMSB15A | thymosin beta 15a |
| TRPV6 | transient receptor potential cation channel, subfamily V, member 6 |
| TTC4 | tetratricopeptide repeat domain 4 |
| VGF | VGF nerve growth factor inducible |
| WDR91 | WD repeat domain 91 |
| ZBTB6 | zinc finger and BTB domain containing 6 |
| ZNF134 | zinc finger protein 134 |
| ZNF492 | zinc finger protein 492 |
| ZNF532 | zinc finger protein 532 |
| ZNF552 | zinc finger protein 552 |
| ZNF747 | zinc finger protein 747 |
