serotonin-4673 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the serotonin-4673 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AAGAB alpha- and gamma-adaptin binding protein
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1
ADGRB2 adhesion G protein-coupled receptor B2
ADRB1 adrenoceptor beta 1
AIRE autoimmune regulator
B9D1 B9 protein domain 1
BTF3P11 basic transcription factor 3 pseudogene 11
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase
C17ORF53 chromosome 17 open reading frame 53
C1ORF159 chromosome 1 open reading frame 159
CADM4 cell adhesion molecule 4
CASP8 caspase 8, apoptosis-related cysteine peptidase
CD79B CD79b molecule, immunoglobulin-associated beta
CDH8 cadherin 8, type 2
CHI3L2 chitinase 3-like 2
CLTB clathrin, light chain B
CNNM2 cyclin and CBS domain divalent metal cation transport mediator 2
COL4A6 collagen, type IV, alpha 6
COMMD4 COMM domain containing 4
CRKL v-crk avian sarcoma virus CT10 oncogene homolog-like
CRP C-reactive protein, pentraxin-related
CSF1 colony stimulating factor 1 (macrophage)
CTNS cystinosin, lysosomal cystine transporter
CXCR4 chemokine (C-X-C motif) receptor 4
DGCR5 DiGeorge syndrome critical region gene 5 (non-protein coding)
DGKA diacylglycerol kinase, alpha 80kDa
DOCK6 dedicator of cytokinesis 6
ELAVL3 ELAV like neuron-specific RNA binding protein 3
ESRRG estrogen-related receptor gamma
FDPS farnesyl diphosphate synthase
FRS3 fibroblast growth factor receptor substrate 3
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila)
GDPD3 glycerophosphodiester phosphodiesterase domain containing 3
GNG7 guanine nucleotide binding protein (G protein), gamma 7
GNRH1 gonadotropin-releasing hormone 1 (luteinizing-releasing hormone)
HAP1 huntingtin-associated protein 1
HEATR6 HEAT repeat containing 6
IGHG1 immunoglobulin heavy constant gamma 1 (G1m marker)
IL2 interleukin 2
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KCTD13 potassium channel tetramerization domain containing 13
KDM6B lysine (K)-specific demethylase 6B
LGALS8 lectin, galactoside-binding, soluble, 8
LPPR4 lipid phosphate phosphatase-related protein type 4
LRCH4 leucine-rich repeats and calponin homology (CH) domain containing 4
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1
LYVE1 lymphatic vessel endothelial hyaluronan receptor 1
MAP1B microtubule-associated protein 1B
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MAPK3 mitogen-activated protein kinase 3
MVB12B multivesicular body subunit 12B
MVD mevalonate (diphospho) decarboxylase
MYO9B myosin IXB
NCAM1 neural cell adhesion molecule 1
NEK9 NIMA-related kinase 9
NF1 neurofibromin 1
NOTCH2 notch 2
OAZ3 ornithine decarboxylase antizyme 3
OGFOD2 2-oxoglutarate and iron-dependent oxygenase domain containing 2
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1
PATZ1 POZ (BTB) and AT hook containing zinc finger 1
PCDHB3 protocadherin beta 3
PCYT1A phosphate cytidylyltransferase 1, choline, alpha
PDGFA platelet-derived growth factor alpha polypeptide
PLEK pleckstrin
PPP1R37 protein phosphatase 1, regulatory subunit 37
PRAMEF11 PRAME family member 11
PRDM2 PR domain containing 2, with ZNF domain
PSD4 pleckstrin and Sec7 domain containing 4
PYHIN1 pyrin and HIN domain family, member 1
RAB31 RAB31, member RAS oncogene family
RAD52 RAD52 homolog (S. cerevisiae)
RB1 retinoblastoma 1
RBMS3 RNA binding motif, single stranded interacting protein 3
RGS12 regulator of G-protein signaling 12
RMND5A required for meiotic nuclear division 5 homolog A (S. cerevisiae)
SELL selectin L
SEMG2 semenogelin II
SLC16A7 solute carrier family 16 (monocarboxylate transporter), member 7
SPAG7 sperm associated antigen 7
ST7L suppression of tumorigenicity 7 like
STX7 syntaxin 7
SUGP1 SURP and G patch domain containing 1
SYMPK symplekin
TBC1D2B TBC1 domain family, member 2B
TFAP2C transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)
TJP3 tight junction protein 3
TLE4 transducin-like enhancer of split 4
TLK1 tousled-like kinase 1
TLR2 toll-like receptor 2
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TXNRD3 thioredoxin reductase 3
TYMS thymidylate synthetase
UTP14A UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast)
WHSC1 Wolf-Hirschhorn syndrome candidate 1
WNT3 wingless-type MMTV integration site family, member 3
XDH xanthine dehydrogenase
YIPF2 Yip1 domain family, member 2
ZNF34 zinc finger protein 34

decreased expression

Symbol Name
A4GALT alpha 1,4-galactosyltransferase
ADAM2 ADAM metallopeptidase domain 2
ADAM23 ADAM metallopeptidase domain 23
AFAP1 actin filament associated protein 1
AGMAT agmatine ureohydrolase (agmatinase)
ALOX12P2 arachidonate 12-lipoxygenase pseudogene 2
ANXA2P1 annexin A2 pseudogene 1
AOC2 amine oxidase, copper containing 2 (retina-specific)
ARMCX4 armadillo repeat containing, X-linked 4
ARRB2 arrestin, beta 2
B3GALT4 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4
BIRC3 baculoviral IAP repeat containing 3
C14ORF79 chromosome 14 open reading frame 79
C22ORF46 chromosome 22 open reading frame 46
C7ORF43 chromosome 7 open reading frame 43
CA11 carbonic anhydrase XI
CAMKMT calmodulin-lysine N-methyltransferase
CCNA1 cyclin A1
CD101 CD101 molecule
CDKL3 cyclin-dependent kinase-like 3
CHML choroideremia-like (Rab escort protein 2)
CIDEB cell death-inducing DFFA-like effector b
CLDN1 claudin 1
CPNE7 copine VII
CYP2R1 cytochrome P450, family 2, subfamily R, polypeptide 1
DDN dendrin
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6
DNAJC28 DnaJ (Hsp40) homolog, subfamily C, member 28
DNM3 dynamin 3
EFNA3 ephrin-A3
EYA4 EYA transcriptional coactivator and phosphatase 4
FAM110B family with sequence similarity 110, member B
FKBP10 FK506 binding protein 10, 65 kDa
FMO4 flavin containing monooxygenase 4
GABRA2 gamma-aminobutyric acid (GABA) A receptor, alpha 2
GLDC glycine dehydrogenase (decarboxylating)
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide
GNG3 guanine nucleotide binding protein (G protein), gamma 3
HIST1H1D histone cluster 1, H1d
HIST1H2AK histone cluster 1, H2ak
HIST1H2BN histone cluster 1, H2bn
HIST1H3I histone cluster 1, H3i
HOXA7 homeobox A7
HOXC8 homeobox C8
KCNA5 potassium channel, voltage gated shaker related subfamily A, member 5
KDM5C lysine (K)-specific demethylase 5C
KIFC1 kinesin family member C1
KLHL25 kelch-like family member 25
KRT20 keratin 20, type I
LHPP phospholysine phosphohistidine inorganic pyrophosphate phosphatase
LOC257152 uncharacterized LOC257152
LRRK1 leucine-rich repeat kinase 1
LTC4S leukotriene C4 synthase
LYPD3 LY6/PLAUR domain containing 3
MAST3 microtubule associated serine/threonine kinase 3
MCMBP minichromosome maintenance complex binding protein
METTL16 methyltransferase like 16
MGP matrix Gla protein
MPP3 membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
MRPL52 mitochondrial ribosomal protein L52
MTHFSD methenyltetrahydrofolate synthetase domain containing
NCS1 neuronal calcium sensor 1
NDE1 nudE neurodevelopment protein 1
NID2 nidogen 2 (osteonidogen)
NLGN1 neuroligin 1
PADI1 peptidyl arginine deiminase, type I
PARM1 prostate androgen-regulated mucin-like protein 1
PCDH12 protocadherin 12
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta
PDE6C phosphodiesterase 6C, cGMP-specific, cone, alpha prime
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)
PLCXD1 phosphatidylinositol-specific phospholipase C, X domain containing 1
PPFIA4 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4
PRR14L proline rich 14-like
RIBC2 RIB43A domain with coiled-coils 2
RNF39 ring finger protein 39
SAMD9 sterile alpha motif domain containing 9
SCN9A sodium channel, voltage gated, type IX alpha subunit
SLC5A2 solute carrier family 5 (sodium/glucose cotransporter), member 2
SLC9A2 solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2
SPATA1 spermatogenesis associated 1
SPRYD7 SPRY domain containing 7
STEAP4 STEAP family member 4
SUGCT succinyl-CoA:glutarate-CoA transferase
SYNGR3 synaptogyrin 3
TADA2A transcriptional adaptor 2A
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TIGD6 tigger transposable element derived 6
TMEM180 transmembrane protein 180
TMEM53 transmembrane protein 53
TTLL1 tubulin tyrosine ligase-like family member 1
TUBA4B tubulin, alpha 4b
WNT10B wingless-type MMTV integration site family, member 10B
ZNF671 zinc finger protein 671
ZNF8 zinc finger protein 8