| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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193 genes differentially expressed following the serotonin-5268 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACVR1B | activin A receptor, type IB |
| ADAMTS13 | ADAM metallopeptidase with thrombospondin type 1 motif, 13 |
| AGGF1 | angiogenic factor with G patch and FHA domains 1 |
| AIM2 | absent in melanoma 2 |
| AKAP13 | A kinase (PRKA) anchor protein 13 |
| AKAP8L | A kinase (PRKA) anchor protein 8-like |
| AP1S1 | adaptor-related protein complex 1, sigma 1 subunit |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 |
| BAX | BCL2-associated X protein |
| BAZ1B | bromodomain adjacent to zinc finger domain, 1B |
| BTN3A3 | butyrophilin, subfamily 3, member A3 |
| CACNB1 | calcium channel, voltage-dependent, beta 1 subunit |
| CCRL2 | chemokine (C-C motif) receptor-like 2 |
| CDK13 | cyclin-dependent kinase 13 |
| CHST1 | carbohydrate (keratan sulfate Gal-6) sulfotransferase 1 |
| CLTA | clathrin, light chain A |
| COL1A1 | collagen, type I, alpha 1 |
| CTNS | cystinosin, lysosomal cystine transporter |
| DENND5B | DENN/MADD domain containing 5B |
| DGCR11 | DiGeorge syndrome critical region gene 11 (non-protein coding) |
| DIAPH2-AS1 | DIAPH2 antisense RNA 1 |
| DIRAS3 | DIRAS family, GTP-binding RAS-like 3 |
| DSTYK | dual serine/threonine and tyrosine protein kinase |
| DYNC1LI2 | dynein, cytoplasmic 1, light intermediate chain 2 |
| EDA | ectodysplasin A |
| ELAVL3 | ELAV like neuron-specific RNA binding protein 3 |
| ELOVL5 | ELOVL fatty acid elongase 5 |
| GHRHR | growth hormone releasing hormone receptor |
| GPR137 | G protein-coupled receptor 137 |
| GPR22 | G protein-coupled receptor 22 |
| GREB1 | growth regulation by estrogen in breast cancer 1 |
| GRM1 | glutamate receptor, metabotropic 1 |
| GSTA1 | glutathione S-transferase alpha 1 |
| GSTTP1 | glutathione S-transferase theta pseudogene 1 |
| HCLS1 | hematopoietic cell-specific Lyn substrate 1 |
| HIST1H1D | histone cluster 1, H1d |
| HIST1H4C | histone cluster 1, H4c |
| HTR1E | 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled |
| INHBE | inhibin, beta E |
| IPW | imprinted in Prader-Willi syndrome (non-protein coding) |
| IRF8 | interferon regulatory factor 8 |
| IRS2 | insulin receptor substrate 2 |
| KAT6A | K(lysine) acetyltransferase 6A |
| KLHL22 | kelch-like family member 22 |
| LINC00094 | long intergenic non-protein coding RNA 94 |
| LMNB1 | lamin B1 |
| MAP1A | microtubule-associated protein 1A |
| MARK2 | MAP/microtubule affinity-regulating kinase 2 |
| MDM4 | MDM4, p53 regulator |
| MECOM | MDS1 and EVI1 complex locus |
| MED31 | mediator complex subunit 31 |
| MPPE1 | metallophosphoesterase 1 |
| NFATC1 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 |
| NOX1 | NADPH oxidase 1 |
| NPM3 | nucleophosmin/nucleoplasmin 3 |
| NRP1 | neuropilin 1 |
| PAPOLA | poly(A) polymerase alpha |
| PBX2 | pre-B-cell leukemia homeobox 2 |
| PI4K2A | phosphatidylinositol 4-kinase type 2 alpha |
| PIK3R5 | phosphoinositide-3-kinase, regulatory subunit 5 |
| PIP5K1A | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha |
| PKN2 | protein kinase N2 |
| PMEL | premelanosome protein |
| PPP1R10 | protein phosphatase 1, regulatory subunit 10 |
| PRDM16 | PR domain containing 16 |
| PRKAB2 | protein kinase, AMP-activated, beta 2 non-catalytic subunit |
| PURA | purine-rich element binding protein A |
| PVRL1 | poliovirus receptor-related 1 (herpesvirus entry mediator C) |
| RAB3B | RAB3B, member RAS oncogene family |
| RAPGEF5 | Rap guanine nucleotide exchange factor (GEF) 5 |
| RORA | RAR-related orphan receptor A |
| RPH3A | rabphilin 3A |
| RPL35A | ribosomal protein L35a |
| SH3BP2 | SH3-domain binding protein 2 |
| SIRT5 | sirtuin 5 |
| SLC1A7 | solute carrier family 1 (glutamate transporter), member 7 |
| SLC24A1 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 1 |
| SLC25A30 | solute carrier family 25, member 30 |
| SLC35E2 | solute carrier family 35, member E2 |
| SLC39A9 | solute carrier family 39, member 9 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase |
| SMG7 | SMG7 nonsense mediated mRNA decay factor |
| SNTA1 | syntrophin, alpha 1 |
| SPOCK2 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2 |
| STAC | SH3 and cysteine rich domain |
| STATH | statherin |
| STK4 | serine/threonine kinase 4 |
| SYDE1 | synapse defective 1, Rho GTPase, homolog 1 (C. elegans) |
| TNFRSF9 | tumor necrosis factor receptor superfamily, member 9 |
| TSC22D2 | TSC22 domain family, member 2 |
| TTLL5 | tubulin tyrosine ligase-like family member 5 |
| USP2 | ubiquitin specific peptidase 2 |
| USP46 | ubiquitin specific peptidase 46 |
| ZBTB44 | zinc finger and BTB domain containing 44 |
| ZC3H7B | zinc finger CCCH-type containing 7B |
| ZFP36L2 | ZFP36 ring finger protein-like 2 |
| ZNF124 | zinc finger protein 124 |
| Symbol | Name |
|---|---|
| A4GALT | alpha 1,4-galactosyltransferase |
| ACADSB | acyl-CoA dehydrogenase, short/branched chain |
| ACTL8 | actin-like 8 |
| ALOX12P2 | arachidonate 12-lipoxygenase pseudogene 2 |
| ALPK1 | alpha-kinase 1 |
| ARHGEF10L | Rho guanine nucleotide exchange factor (GEF) 10-like |
| ARHGEF11 | Rho guanine nucleotide exchange factor (GEF) 11 |
| B9D2 | B9 protein domain 2 |
| BACE1 | beta-site APP-cleaving enzyme 1 |
| BAHCC1 | BAH domain and coiled-coil containing 1 |
| BMP4 | bone morphogenetic protein 4 |
| BTBD2 | BTB (POZ) domain containing 2 |
| C14ORF79 | chromosome 14 open reading frame 79 |
| C2ORF27A | chromosome 2 open reading frame 27A |
| CAPN15 | calpain 15 |
| CCDC69 | coiled-coil domain containing 69 |
| CENPI | centromere protein I |
| CEP295 | centrosomal protein 295kDa |
| CHPF | chondroitin polymerizing factor |
| CLSTN2 | calsyntenin 2 |
| CNNM4 | cyclin and CBS domain divalent metal cation transport mediator 4 |
| CYHR1 | cysteine/histidine-rich 1 |
| DGAT1 | diacylglycerol O-acyltransferase 1 |
| DNAL4 | dynein, axonemal, light chain 4 |
| DOCK1 | dedicator of cytokinesis 1 |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| ETV6 | ets variant 6 |
| EVPL | envoplakin |
| FAM46C | family with sequence similarity 46, member C |
| FBXO31 | F-box protein 31 |
| FBXO4 | F-box protein 4 |
| FRMD1 | FERM domain containing 1 |
| GALNT12 | polypeptide N-acetylgalactosaminyltransferase 12 |
| GINS4 | GINS complex subunit 4 (Sld5 homolog) |
| GPATCH2L | G patch domain containing 2-like |
| GTF2H3 | general transcription factor IIH, polypeptide 3, 34kDa |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HLA-J | major histocompatibility complex, class I, J (pseudogene) |
| HOXA4 | homeobox A4 |
| KDM7A | lysine (K)-specific demethylase 7A |
| KDM8 | lysine (K)-specific demethylase 8 |
| KLHL12 | kelch-like family member 12 |
| LIN7A | lin-7 homolog A (C. elegans) |
| LMCD1 | LIM and cysteine-rich domains 1 |
| LY6D | lymphocyte antigen 6 complex, locus D |
| MAP3K6 | mitogen-activated protein kinase kinase kinase 6 |
| MC1R | melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor) |
| MGAT4A | mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A |
| MRPS18C | mitochondrial ribosomal protein S18C |
| MTCP1 | mature T-cell proliferation 1 |
| NT5E | 5'-nucleotidase, ecto (CD73) |
| NUDT18 | nudix (nucleoside diphosphate linked moiety X)-type motif 18 |
| NXPE3 | neurexophilin and PC-esterase domain family, member 3 |
| OR2B6 | olfactory receptor, family 2, subfamily B, member 6 |
| OR2F1 | olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene) |
| OSMR | oncostatin M receptor |
| PDE6B | phosphodiesterase 6B, cGMP-specific, rod, beta |
| PGM1 | phosphoglucomutase 1 |
| PIPOX | pipecolic acid oxidase |
| PLA2G4C | phospholipase A2, group IVC (cytosolic, calcium-independent) |
| PRKAR1B | protein kinase, cAMP-dependent, regulatory, type I, beta |
| PYGB | phosphorylase, glycogen; brain |
| RAB30 | RAB30, member RAS oncogene family |
| RAD51AP1 | RAD51 associated protein 1 |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 |
| RASSF2 | Ras association (RalGDS/AF-6) domain family member 2 |
| RPAP1 | RNA polymerase II associated protein 1 |
| S100A7 | S100 calcium binding protein A7 |
| SCHIP1 | schwannomin interacting protein 1 |
| SERPINA5 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 |
| SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 |
| SGCG | sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein) |
| SLC27A6 | solute carrier family 27 (fatty acid transporter), member 6 |
| SLIT2 | slit homolog 2 (Drosophila) |
| SLPI | secretory leukocyte peptidase inhibitor |
| SPIDR | scaffolding protein involved in DNA repair |
| SPINK5 | serine peptidase inhibitor, Kazal type 5 |
| STX1A | syntaxin 1A (brain) |
| TBX19 | T-box 19 |
| TEP1 | telomerase-associated protein 1 |
| TMEM242 | transmembrane protein 242 |
| TNFSF18 | tumor necrosis factor (ligand) superfamily, member 18 |
| TRDMT1 | tRNA aspartic acid methyltransferase 1 |
| TRIM16 | tripartite motif containing 16 |
| TRMT2B | tRNA methyltransferase 2 homolog B (S. cerevisiae) |
| UAP1L1 | UDP-N-acetylglucosamine pyrophosphorylase 1 like 1 |
| UBQLN4 | ubiquilin 4 |
| USB1 | U6 snRNA biogenesis 1 |
| VWA1 | von Willebrand factor A domain containing 1 |
| YIF1B | Yip1 interacting factor homolog B (S. cerevisiae) |
| ZDHHC11 | zinc finger, DHHC-type containing 11 |
| ZNF276 | zinc finger protein 276 |
| ZNF480 | zinc finger protein 480 |
| ZNF510 | zinc finger protein 510 |
| ZNF652 | zinc finger protein 652 |
| ZNF696 | zinc finger protein 696 |
