serotonin Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description A primary amino compound that is the 5-hydroxy derivative of tryptamine. (Chemical Entities of Biological Interest Ontology, CHEBI_28790)
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Genes

110 genes co-occuring with the biological term serotonin in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ACE angiotensin I converting enzyme
ADCYAP1R1 adenylate cyclase activating polypeptide 1 (pituitary) receptor type I
ADORA2B adenosine A2b receptor
ADRB1 adrenoceptor beta 1
AGER advanced glycosylation end product-specific receptor
AHI1 Abelson helper integration site 1
ANKK1 ankyrin repeat and kinase domain containing 1
BCHE butyrylcholinesterase
BDNF brain-derived neurotrophic factor
BMP7 bone morphogenetic protein 7
CALM1 calmodulin 1 (phosphorylase kinase, delta)
CAV1 caveolin 1, caveolae protein, 22kDa
CC2D1A coiled-coil and C2 domain containing 1A
CCL11 chemokine (C-C motif) ligand 11
CHGA chromogranin A
CHRNA4 cholinergic receptor, nicotinic, alpha 4 (neuronal)
COMT catechol-O-methyltransferase
CRH corticotropin releasing hormone
CRHR1 corticotropin releasing hormone receptor 1
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6
DRD2 dopamine receptor D2
DRD4 dopamine receptor D4
DTNBP1 dystrobrevin binding protein 1
EDN1 endothelin 1
EGF epidermal growth factor
ESR1 estrogen receptor 1
F3 coagulation factor III (thromboplastin, tissue factor)
FEV FEV (ETS oncogene family)
FOXO3 forkhead box O3
GABRA6 gamma-aminobutyric acid (GABA) A receptor, alpha 6
GALM galactose mutarotase (aldose 1-epimerase)
GCH1 GTP cyclohydrolase 1
GLRA1 glycine receptor, alpha 1
GNB3 guanine nucleotide binding protein (G protein), beta polypeptide 3
GPM6B glycoprotein M6B
GSK3B glycogen synthase kinase 3 beta
HDAC1 histone deacetylase 1
HDAC3 histone deacetylase 3
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
HSPA1A heat shock 70kDa protein 1A
HTOR 5-hydroxytryptamine (serotonin) oxygenase regulator
HTR1A 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled
HTR1B 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled
HTR1D 5-hydroxytryptamine (serotonin) receptor 1D, G protein-coupled
HTR2A 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
HTR2B 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled
HTR2C 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled
HTR3A 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic
HTR3B 5-hydroxytryptamine (serotonin) receptor 3B, ionotropic
HTR3C 5-hydroxytryptamine (serotonin) receptor 3C, ionotropic
HTR4 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled
HTR5A 5-hydroxytryptamine (serotonin) receptor 5A, G protein-coupled
HTR6 5-hydroxytryptamine (serotonin) receptor 6, G protein-coupled
HTR7 5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled
IL6 interleukin 6
INPP1 inositol polyphosphate-1-phosphatase
INS insulin
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit)
ITGAX integrin, alpha X (complement component 3 receptor 4 subunit)
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
LEPR leptin receptor
LRP5 low density lipoprotein receptor-related protein 5
MAOA monoamine oxidase A
MAOB monoamine oxidase B
MAPK1 mitogen-activated protein kinase 1
MAPK14 mitogen-activated protein kinase 14
MAPK3 mitogen-activated protein kinase 3
MIR15A microRNA 15a
MIR16-1 microRNA 16-1
MPO myeloperoxidase
NOS3 nitric oxide synthase 3 (endothelial cell)
NR4A1 nuclear receptor subfamily 4, group A, member 1
OPRM1 opioid receptor, mu 1
OXT oxytocin/neurophysin I prepropeptide
P2RX7 purinergic receptor P2X, ligand gated ion channel, 7
POMC proopiomelanocortin
PPARG peroxisome proliferator-activated receptor gamma
PRKCD protein kinase C, delta
PTAFR platelet-activating factor receptor
PTHLH parathyroid hormone-like hormone
PYY peptide YY
RAPGEF3 Rap guanine nucleotide exchange factor (GEF) 3
RHO rhodopsin
ROCK1 Rho-associated, coiled-coil containing protein kinase 1
SEC24C SEC24 family member C
SEC24D SEC24 family member D
SELP selectin P (granule membrane protein 140kDa, antigen CD62)
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SIGLEC7 sialic acid binding Ig-like lectin 7
SIGLEC9 sialic acid binding Ig-like lectin 9
SLC18A1 solute carrier family 18 (vesicular monoamine transporter), member 1
SLC22A1 solute carrier family 22 (organic cation transporter), member 1
SLC29A4 solute carrier family 29 (equilibrative nucleoside transporter), member 4
SLC6A14 solute carrier family 6 (amino acid transporter), member 14
SLC6A2 solute carrier family 6 (neurotransmitter transporter), member 2
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4
SORL1 sortilin-related receptor, L(DLR class) A repeats containing
SRC SRC proto-oncogene, non-receptor tyrosine kinase
SYP synaptophysin
THBS1 thrombospondin 1
TP53 tumor protein p53
TPH1 tryptophan hydroxylase 1
TPH2 tryptophan hydroxylase 2
VEGFA vascular endothelial growth factor A
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta