sertaconazole-6128 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the sertaconazole-6128 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADARB1 adenosine deaminase, RNA-specific, B1
AGAP2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
APBA2 amyloid beta (A4) precursor protein-binding, family A, member 2
ARHGAP44 Rho GTPase activating protein 44
ATHL1 ATH1, acid trehalase-like 1 (yeast)
ATP13A2 ATPase type 13A2
AURKA aurora kinase A
BCL3 B-cell CLL/lymphoma 3
C19ORF66 chromosome 19 open reading frame 66
C2ORF27A chromosome 2 open reading frame 27A
CARF calcium responsive transcription factor
CASP5 caspase 5, apoptosis-related cysteine peptidase
CCDC57 coiled-coil domain containing 57
CCND1 cyclin D1
CD160 CD160 molecule
CD59 CD59 molecule, complement regulatory protein
CDK10 cyclin-dependent kinase 10
CES3 carboxylesterase 3
CNNM2 cyclin and CBS domain divalent metal cation transport mediator 2
CNNM4 cyclin and CBS domain divalent metal cation transport mediator 4
COL11A2 collagen, type XI, alpha 2
COL18A1 collagen, type XVIII, alpha 1
CRTC1 CREB regulated transcription coactivator 1
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6
DDR1 discoidin domain receptor tyrosine kinase 1
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
DPEP2 dipeptidase 2
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase
ELAC2 elaC ribonuclease Z 2
ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7
FSTL3 follistatin-like 3 (secreted glycoprotein)
GABRA2 gamma-aminobutyric acid (GABA) A receptor, alpha 2
GPD1 glycerol-3-phosphate dehydrogenase 1 (soluble)
GPM6B glycoprotein M6B
GUCY1B2 guanylate cyclase 1, soluble, beta 2 (pseudogene)
HABP4 hyaluronan binding protein 4
HCFC1 host cell factor C1
HIST1H2BJ histone cluster 1, H2bj
HLA-DRB6 major histocompatibility complex, class II, DR beta 6 (pseudogene)
HPCAL4 hippocalcin like 4
HR hair growth associated
IGHG1 immunoglobulin heavy constant gamma 1 (G1m marker)
IL16 interleukin 16
ING4 inhibitor of growth family, member 4
IRS4 insulin receptor substrate 4
IZUMO4 IZUMO family member 4
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2
KDM4B lysine (K)-specific demethylase 4B
KHSRP KH-type splicing regulatory protein
LECT1 leukocyte cell derived chemotaxin 1
LMF1 lipase maturation factor 1
LOC647070 uncharacterized LOC647070
LPAR1 lysophosphatidic acid receptor 1
MAGEA6 melanoma antigen family A6
MAPRE3 microtubule-associated protein, RP/EB family, member 3
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
NUDT18 nudix (nucleoside diphosphate linked moiety X)-type motif 18
NXPH4 neurexophilin 4
OXCT2 3-oxoacid CoA transferase 2
PARP3 poly (ADP-ribose) polymerase family, member 3
PER3 period circadian clock 3
PLAC1 placenta-specific 1
PLIN2 perilipin 2
PML promyelocytic leukemia
PNMA3 paraneoplastic Ma antigen 3
PPAP2B phosphatidic acid phosphatase type 2B
PRKCE protein kinase C, epsilon
PTGDS prostaglandin D2 synthase 21kDa (brain)
RET ret proto-oncogene
RFC1 replication factor C (activator 1) 1, 145kDa
RFX2 regulatory factor X, 2 (influences HLA class II expression)
RPS6KA4 ribosomal protein S6 kinase, 90kDa, polypeptide 4
RUNX1T1 runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
SAMD14 sterile alpha motif domain containing 14
SH3GLB2 SH3-domain GRB2-like endophilin B2
SHC3 SHC (Src homology 2 domain containing) transforming protein 3
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3
SLC22A5 solute carrier family 22 (organic cation/carnitine transporter), member 5
SLC26A4 solute carrier family 26 (anion exchanger), member 4
SLC48A1 solute carrier family 48 (heme transporter), member 1
SLC5A2 solute carrier family 5 (sodium/glucose cotransporter), member 2
SNW1 SNW domain containing 1
SOX4 SRY (sex determining region Y)-box 4
SRPK3 SRSF protein kinase 3
SSTR5 somatostatin receptor 5
STON1 stonin 1
SWAP70 SWAP switching B-cell complex 70kDa subunit
TCF4 transcription factor 4
TERT telomerase reverse transcriptase
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TGFB1I1 transforming growth factor beta 1 induced transcript 1
THTPA thiamine triphosphatase
TPMT thiopurine S-methyltransferase
TRPM1 transient receptor potential cation channel, subfamily M, member 1
UBR2 ubiquitin protein ligase E3 component n-recognin 2
VAV2 vav 2 guanine nucleotide exchange factor
WIZ widely interspaced zinc finger motifs
WTAP Wilms tumor 1 associated protein
WWC1 WW and C2 domain containing 1
ZNF93 zinc finger protein 93

decreased expression

Symbol Name
ABHD17B abhydrolase domain containing 17B
APOBEC3C apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C
ARG1 arginase 1
ARL15 ADP-ribosylation factor-like 15
ARMC4 armadillo repeat containing 4
AVPI1 arginine vasopressin-induced 1
BPHL biphenyl hydrolase-like (serine hydrolase)
C11ORF63 chromosome 11 open reading frame 63
C7ORF69 chromosome 7 open reading frame 69
CAPN5 calpain 5
CBX4 chromobox homolog 4
CD320 CD320 molecule
CELP carboxyl ester lipase pseudogene
CEP170B centrosomal protein 170B
CHM choroideremia (Rab escort protein 1)
CHRNA5 cholinergic receptor, nicotinic, alpha 5 (neuronal)
CLCF1 cardiotrophin-like cytokine factor 1
CPTP ceramide-1-phosphate transfer protein
CRMP1 collapsin response mediator protein 1
CXORF56 chromosome X open reading frame 56
DCAF17 DDB1 and CUL4 associated factor 17
DEPDC5 DEP domain containing 5
DHRS3 dehydrogenase/reductase (SDR family) member 3
DNAL4 dynein, axonemal, light chain 4
DNMBP dynamin binding protein
DUSP4 dual specificity phosphatase 4
EYA3 EYA transcriptional coactivator and phosphatase 3
FGGY FGGY carbohydrate kinase domain containing
FMOD fibromodulin
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GDPD3 glycerophosphodiester phosphodiesterase domain containing 3
GID4 GID complex subunit 4
GP6 glycoprotein VI (platelet)
GSDMD gasdermin D
GTF2A1 general transcription factor IIA, 1, 19/37kDa
HCAR3 hydroxycarboxylic acid receptor 3
HIST1H2BN histone cluster 1, H2bn
HIST1H3H histone cluster 1, H3h
HIST1H4A histone cluster 1, H4a
HNRNPA3P1 heterogeneous nuclear ribonucleoprotein A3 pseudogene 1
HYAL3 hyaluronoglucosaminidase 3
IFIT2 interferon-induced protein with tetratricopeptide repeats 2
IFNAR1 interferon (alpha, beta and omega) receptor 1
IGLV1-44 immunoglobulin lambda variable 1-44
IL12RB1 interleukin 12 receptor, beta 1
INF2 inverted formin, FH2 and WH2 domain containing
IRF2BP1 interferon regulatory factor 2 binding protein 1
ITIH2 inter-alpha-trypsin inhibitor heavy chain 2
LILRB4 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 4
LNPEP leucyl/cystinyl aminopeptidase
LOC157562 uncharacterized LOC157562
LOC390998 ribosomal protein L10 pseudogene
LOC730101 uncharacterized LOC730101
LOXL3 lysyl oxidase-like 3
LTC4S leukotriene C4 synthase
LYRM9 LYR motif containing 9
MAGEH1 melanoma antigen family H1
MAK male germ cell-associated kinase
MAP3K7CL MAP3K7 C-terminal like
MBOAT2 membrane bound O-acyltransferase domain containing 2
MBTPS2 membrane-bound transcription factor peptidase, site 2
MDM4 MDM4, p53 regulator
MMRN2 multimerin 2
MNX1 motor neuron and pancreas homeobox 1
MOCS3 molybdenum cofactor synthesis 3
MPDU1 mannose-P-dolichol utilization defect 1
MTHFS 5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase)
MTMR12 myotubularin related protein 12
MXD3 MAX dimerization protein 3
NDE1 nudE neurodevelopment protein 1
NOD2 nucleotide-binding oligomerization domain containing 2
NT5E 5'-nucleotidase, ecto (CD73)
OMG oligodendrocyte myelin glycoprotein
OR7E156P olfactory receptor, family 7, subfamily E, member 156 pseudogene
PDE12 phosphodiesterase 12
PGGT1B protein geranylgeranyltransferase type I, beta subunit
POLM polymerase (DNA directed), mu
POM121L2 POM121 transmembrane nucleoporin-like 2
PRF1 perforin 1 (pore forming protein)
PYGB phosphorylase, glycogen; brain
RAB11B RAB11B, member RAS oncogene family
RAB33A RAB33A, member RAS oncogene family
RASAL1 RAS protein activator like 1 (GAP1 like)
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase
RNPEPL1 arginyl aminopeptidase (aminopeptidase B)-like 1
SGCE sarcoglycan, epsilon
SPATA1 spermatogenesis associated 1
TCTN2 tectonic family member 2
TGFBR1 transforming growth factor, beta receptor 1
TRAF1 TNF receptor-associated factor 1
TTLL1 tubulin tyrosine ligase-like family member 1
TWSG1 twisted gastrulation BMP signaling modulator 1
UPK3A uroplakin 3A
ZBTB38 zinc finger and BTB domain containing 38
ZIC3 Zic family member 3
ZNF493 zinc finger protein 493