sertraline Gene Set

Dataset	GeneRIF Biological Term Annotations
Category	structural or functional annotations
Type	biological term
Description	A member of the class of tetralins that is tetralin which is substituted at positions 1 and 4 by a methylamino and a 3,4-dichlorophenyl group, respectively (the S,S diastereoisomer). A selective serotonin-reuptake inhibitor (SSRI), it is administered orally as the hydrochloride salt as an antidepressant for the treatment of depression, obsessive-compulsive disorder, panic disorder and post-traumatic stress disorder. (Chemical Entities of Biological Interest Ontology, CHEBI_9123)
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Genes

7 genes co-occuring with the biological term sertraline in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol	Name
ACHE	acetylcholinesterase (Yt blood group)
BCHE	butyrylcholinesterase
DDIT4	DNA-damage-inducible transcript 4
DIO1	deiodinase, iodothyronine, type I
MTOR	mechanistic target of rapamycin (serine/threonine kinase)
SLC36A1	solute carrier family 36 (proton/amino acid symporter), member 1
SLC6A4	solute carrier family 6 (neurotransmitter transporter), member 4