setdb1 Gene Set

Dataset	GeneRIF Biological Term Annotations
Category	structural or functional annotations
Type	biological term
Description	SET domain, bifurcated 1\|This gene encodes a histone methyltransferase which regulates histone methylation, gene silencing, and transcriptional repression. This gene has been identified as a target for treatment in Huntington Disease, given that gene silencing and transcription dysfunction likely play a role in the disease pathogenesis. Alternatively spliced transcript variants of this gene have been described.[provided by RefSeq, Jun 2011] (NCBI Entrez Gene Database, 9869)
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Genes

11 genes co-occuring with the biological term setdb1 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol	Name
AKT1	v-akt murine thymoma viral oncogene homolog 1
CBX5	chromobox homolog 5
CDKN2A	cyclin-dependent kinase inhibitor 2A
CHAF1B	chromatin assembly factor 1, subunit B (p60)
DNMT3A	DNA (cytosine-5-)-methyltransferase 3 alpha
KDM1A	lysine (K)-specific demethylase 1A
MBD1	methyl-CpG binding domain protein 1
PPARG	peroxisome proliferator-activated receptor gamma
SETDB1	SET domain, bifurcated 1
TRIM28	tripartite motif containing 28
ZNF274	zinc finger protein 274