seven Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
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Genes

397 genes co-occuring with the biological term seven in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ABCA4 ATP-binding cassette, sub-family A (ABC1), member 4
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group)
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2
ABCC8 ATP-binding cassette, sub-family C (CFTR/MRP), member 8
ABCD1 ATP-binding cassette, sub-family D (ALD), member 1
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
ACADM acyl-CoA dehydrogenase, C-4 to C-12 straight chain
ACKR1 atypical chemokine receptor 1 (Duffy blood group)
ACTC1 actin, alpha, cardiac muscle 1
ADAM33 ADAM metallopeptidase domain 33
ADGRV1 adhesion G protein-coupled receptor V1
ADH4 alcohol dehydrogenase 4 (class II), pi polypeptide
ADRB2 adrenoceptor beta 2, surface
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AK2 adenylate kinase 2
ALAS2 5'-aminolevulinate synthase 2
ALDH3A2 aldehyde dehydrogenase 3 family, member A2
ALDH7A1 aldehyde dehydrogenase 7 family, member A1
ALDOB aldolase B, fructose-bisphosphate
ALG1 ALG1, chitobiosyldiphosphodolichol beta-mannosyltransferase
AMELY amelogenin, Y-linked
ANG angiogenin, ribonuclease, RNase A family, 5
ANOS1 anosmin 1
APC adenomatous polyposis coli
APP amyloid beta (A4) precursor protein
ARFGEF1 ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited)
ARRDC4 arrestin domain containing 4
ARSB arylsulfatase B
ATG16L1 autophagy related 16-like 1 (S. cerevisiae)
ATL1 atlastin GTPase 1
ATM ATM serine/threonine kinase
ATP1A2 ATPase, Na+/K+ transporting, alpha 2 polypeptide
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
ATP2C1 ATPase, Ca++ transporting, type 2C, member 1
B2M beta-2-microglobulin
BAD BCL2-associated agonist of cell death
BAX BCL2-associated X protein
BBC3 BCL2 binding component 3
BCL2L1 BCL2-like 1
BRAF B-Raf proto-oncogene, serine/threonine kinase
BRCA1 breast cancer 1, early onset
BRCA2 breast cancer 2, early onset
C4BPA complement component 4 binding protein, alpha
C4BPB complement component 4 binding protein, beta
C5 complement component 5
CA10 carbonic anhydrase X
CACNA1A calcium channel, voltage-dependent, P/Q type, alpha 1A subunit
CALB2 calbindin 2
CAMK2A calcium/calmodulin-dependent protein kinase II alpha
CASR calcium-sensing receptor
CAV1 caveolin 1, caveolae protein, 22kDa
CBS cystathionine-beta-synthase
CCND1 cyclin D1
CCND3 cyclin D3
CCR2 chemokine (C-C motif) receptor 2
CD209 CD209 molecule
CD58 CD58 molecule
CD81 CD81 molecule
CDC73 cell division cycle 73
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDK2AP1 cyclin-dependent kinase 2 associated protein 1
CDKAL1 CDK5 regulatory subunit associated protein 1-like 1
CDKL5 cyclin-dependent kinase-like 5
CDKN2A cyclin-dependent kinase inhibitor 2A
CFH complement factor H
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
CHRNE cholinergic receptor, nicotinic, epsilon (muscle)
CHST6 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 6
CIB1 calcium and integrin binding 1 (calmyrin)
CLCNKB chloride channel, voltage-sensitive Kb
CLSPN claspin
CNBP CCHC-type zinc finger, nucleic acid binding protein
COL4A4 collagen, type IV, alpha 4
CPT1A carnitine palmitoyltransferase 1A (liver)
CRB1 crumbs family member 1, photoreceptor morphogenesis associated
CRH corticotropin releasing hormone
CRP C-reactive protein, pentraxin-related
CTNNAL1 catenin (cadherin-associated protein), alpha-like 1
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CXCL12 chemokine (C-X-C motif) ligand 12
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2
CYP21A2 cytochrome P450, family 21, subfamily A, polypeptide 2
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
CYP4V2 cytochrome P450, family 4, subfamily V, polypeptide 2
DBH dopamine beta-hydroxylase (dopamine beta-monooxygenase)
DCBLD2 discoidin, CUB and LCCL domain containing 2
DGKH diacylglycerol kinase, eta
DHCR7 7-dehydrocholesterol reductase
DICER1 dicer 1, ribonuclease type III
DLG4 discs, large homolog 4 (Drosophila)
DMD dystrophin
DMPK dystrophia myotonica-protein kinase
DRD2 dopamine receptor D2
DRD3 dopamine receptor D3
DRD5 dopamine receptor D5
DSC2 desmocollin 2
DSG2 desmoglein 2
DSP desmoplakin
ECM1 extracellular matrix protein 1
EGLN1 egl-9 family hypoxia-inducible factor 1
ELN elastin
EPO erythropoietin
ERBB2 erb-b2 receptor tyrosine kinase 2
ERCC1 excision repair cross-complementation group 1
ESR1 estrogen receptor 1
ESR2 estrogen receptor 2 (ER beta)
EXO1 exonuclease 1
EXT1 exostosin glycosyltransferase 1
EXT2 exostosin glycosyltransferase 2
F10 coagulation factor X
F11 coagulation factor XI
F12 coagulation factor XII (Hageman factor)
F7 coagulation factor VII (serum prothrombin conversion accelerator)
F8 coagulation factor VIII, procoagulant component
FADS1 fatty acid desaturase 1
FADS2 fatty acid desaturase 2
FERMT1 fermitin family member 1
FGB fibrinogen beta chain
FGF2 fibroblast growth factor 2 (basic)
FGF23 fibroblast growth factor 23
FGFR1 fibroblast growth factor receptor 1
FGFR2 fibroblast growth factor receptor 2
FLT1 fms-related tyrosine kinase 1
FLT4 fms-related tyrosine kinase 4
FN1 fibronectin 1
FOXC2 forkhead box C2
FOXG1 forkhead box G1
FOXL2 forkhead box L2
FTO fat mass and obesity associated
FUT1 fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group)
FUT2 fucosyltransferase 2 (secretor status included)
FZD4 frizzled class receptor 4
GABRE gamma-aminobutyric acid (GABA) A receptor, epsilon
GATA4 GATA binding protein 4
GBA glucosidase, beta, acid
GCGR glucagon receptor
GCK glucokinase (hexokinase 4)
GH1 growth hormone 1
GLRA1 glycine receptor, alpha 1
GLS glutaminase
GNE glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase
GPX1 glutathione peroxidase 1
GRIN2A glutamate receptor, ionotropic, N-methyl D-aspartate 2A
GRIN3A glutamate receptor, ionotropic, N-methyl-D-aspartate 3A
GSTP1 glutathione S-transferase pi 1
H19 H19, imprinted maternally expressed transcript (non-protein coding)
HABP2 hyaluronan binding protein 2
HBB hemoglobin, beta
HBD hemoglobin, delta
HESX1 HESX homeobox 1
HEXB hexosaminidase B (beta polypeptide)
HFE hemochromatosis
HLA-G major histocompatibility complex, class I, G
HMBS hydroxymethylbilane synthase
HNF1A HNF1 homeobox A
HNF4A hepatocyte nuclear factor 4, alpha
HOGA1 4-hydroxy-2-oxoglutarate aldolase 1
HPS1 Hermansky-Pudlak syndrome 1
HPS4 Hermansky-Pudlak syndrome 4
HPS5 Hermansky-Pudlak syndrome 5
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1
HSPD1 heat shock 60kDa protein 1 (chaperonin)
HTR1B 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled
HTR2A 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
HTT huntingtin
ICAM4 intercellular adhesion molecule 4 (Landsteiner-Wiener blood group)
IGF1R insulin-like growth factor 1 receptor
IGF2BP2 insulin-like growth factor 2 mRNA binding protein 2
IGK immunoglobulin kappa locus
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
IL1R1 interleukin 1 receptor, type I
IL7 interleukin 7
INF2 inverted formin, FH2 and WH2 domain containing
INS insulin
IRF6 interferon regulatory factor 6
ISL1 ISL LIM homeobox 1
ISPD isoprenoid synthase domain containing
ITGA2B integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
ITGAV integrin, alpha V
ITGB4 integrin, beta 4
JAK2 Janus kinase 2
JUP junction plakoglobin
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2
KCNQ1 potassium channel, voltage gated KQT-like subfamily Q, member 1
KEAP1 kelch-like ECH-associated protein 1
KIAA0319 KIAA0319
KIF21A kinesin family member 21A
KMT2A lysine (K)-specific methyltransferase 2A
KMT2D lysine (K)-specific methyltransferase 2D
KPNA2 karyopherin alpha 2 (RAG cohort 1, importin alpha 1)
KRAS Kirsten rat sarcoma viral oncogene homolog
L2HGDH L-2-hydroxyglutarate dehydrogenase
LACRT lacritin
LAMA1 laminin, alpha 1
LDLR low density lipoprotein receptor
LEP leptin
LGI1 leucine-rich, glioma inactivated 1
LGI4 leucine-rich repeat LGI family, member 4
LHB luteinizing hormone beta polypeptide
LPA lipoprotein, Lp(a)
LRP5 low density lipoprotein receptor-related protein 5
LRP8 low density lipoprotein receptor-related protein 8, apolipoprotein e receptor
LRRK2 leucine-rich repeat kinase 2
LTA lymphotoxin alpha
MAP2K2 mitogen-activated protein kinase kinase 2
MATN3 matrilin 3
MBTPS1 membrane-bound transcription factor peptidase, site 1
MC4R melanocortin 4 receptor
MCAM melanoma cell adhesion molecule
MECP2 methyl CpG binding protein 2
MEF2A myocyte enhancer factor 2A
MEN1 multiple endocrine neoplasia I
MICA MHC class I polypeptide-related sequence A
MIR106A microRNA 106a
MIR150 microRNA 150
MIR17 microRNA 17
MIR20A microRNA 20a
MIR34A microRNA 34a
MITF microphthalmia-associated transcription factor
MLH3 mutL homolog 3
MMP1 matrix metallopeptidase 1
MPP5 membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5)
MPV17 MpV17 mitochondrial inner membrane protein
MPZ myelin protein zero
MS4A1 membrane-spanning 4-domains, subfamily A, member 1
MSH2 mutS homolog 2
MT-TK tRNA
MTAP methylthioadenosine phosphorylase
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MUC1 mucin 1, cell surface associated
MUC16 mucin 16, cell surface associated
MUTYH mutY homolog
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog
MYH7 myosin, heavy chain 7, cardiac muscle, beta
MYH9 myosin, heavy chain 9, non-muscle
MYO15A myosin XVA
MYO5B myosin VB
NDOR1 NADPH dependent diflavin oxidoreductase 1
NEGR1 neuronal growth regulator 1
NF1 neurofibromin 1
NFE2L2 nuclear factor, erythroid 2-like 2
NKX2-1 NK2 homeobox 1
NOS1 nitric oxide synthase 1 (neuronal)
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin)
NPY2R neuropeptide Y receptor Y2
NQO1 NAD(P)H dehydrogenase, quinone 1
NR1I2 nuclear receptor subfamily 1, group I, member 2
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NRG1 neuregulin 1
NSD1 nuclear receptor binding SET domain protein 1
NT5C2 5'-nucleotidase, cytosolic II
NYX nyctalopin
OCRL oculocerebrorenal syndrome of Lowe
OFD1 oral-facial-digital syndrome 1
OTC ornithine carbamoyltransferase
P2RX7 purinergic receptor P2X, ligand gated ion channel, 7
PAH phenylalanine hydroxylase
PALB2 partner and localizer of BRCA2
PAPPA2 pappalysin 2
PARK2 parkin RBR E3 ubiquitin protein ligase
PAX2 paired box 2
PAX3 paired box 3
PCDH15 protocadherin-related 15
PGR progesterone receptor
PHEX phosphate regulating endopeptidase homolog, X-linked
PHF6 PHD finger protein 6
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PITX2 paired-like homeodomain 2
PKN2 protein kinase N2
PKP2 plakophilin 2
PLA2G7 phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
PML promyelocytic leukemia
PMS2 PMS2 postmeiotic segregation increased 2 (S. cerevisiae)
PNP purine nucleoside phosphorylase
PNPLA3 patatin-like phospholipase domain containing 3
POLG polymerase (DNA directed), gamma
POLH polymerase (DNA directed), eta
POMC proopiomelanocortin
PON1 paraoxonase 1
PON3 paraoxonase 3
POU1F1 POU class 1 homeobox 1
PRF1 perforin 1 (pore forming protein)
PRKCDBP protein kinase C, delta binding protein
PRNP prion protein
PROC protein C (inactivator of coagulation factors Va and VIIIa)
PROP1 PROP paired-like homeobox 1
PROS1 protein S (alpha)
PTCH1 patched 1
PTEN phosphatase and tensin homolog
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
RAB3GAP1 RAB3 GTPase activating protein subunit 1 (catalytic)
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RB1 retinoblastoma 1
RET ret proto-oncogene
RHOA ras homolog family member A
RICTOR RPTOR independent companion of MTOR, complex 2
RUNX1 runt-related transcription factor 1
RUNX1T1 runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
RYR1 ryanodine receptor 1 (skeletal)
RYR2 ryanodine receptor 2 (cardiac)
S100A8 S100 calcium binding protein A8
SACS sacsin molecular chaperone
SALL4 spalt-like transcription factor 4
SCARB2 scavenger receptor class B, member 2
SCN1A sodium channel, voltage gated, type I alpha subunit
SEPT9 septin 9
SERPINB7 serpin peptidase inhibitor, clade B (ovalbumin), member 7
SERPINC1 serpin peptidase inhibitor, clade C (antithrombin), member 1
SH2B1 SH2B adaptor protein 1
SHH sonic hedgehog
SIAH1 siah E3 ubiquitin protein ligase 1
SIX3 SIX homeobox 3
SLA2 Src-like-adaptor 2
SLC10A2 solute carrier family 10 (sodium/bile acid cotransporter), member 2
SLC12A3 solute carrier family 12 (sodium/chloride transporter), member 3
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1
SLC22A1 solute carrier family 22 (organic cation transporter), member 1
SLC22A2 solute carrier family 22 (organic cation transporter), member 2
SLC24A5 solute carrier family 24 (sodium/potassium/calcium exchanger), member 5
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13
SLC26A1 solute carrier family 26 (anion exchanger), member 1
SLC26A2 solute carrier family 26 (anion exchanger), member 2
SLC26A4 solute carrier family 26 (anion exchanger), member 4
SLC45A2 solute carrier family 45, member 2
SLC47A1 solute carrier family 47 (multidrug and toxin extrusion), member 1
SLC4A11 solute carrier family 4, sodium borate transporter, member 11
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4
SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1
SMPD1 sphingomyelin phosphodiesterase 1, acid lysosomal
SOD1 superoxide dismutase 1, soluble
SOD3 superoxide dismutase 3, extracellular
SOX10 SRY (sex determining region Y)-box 10
SOX2 SRY (sex determining region Y)-box 2
SPAST spastin
SPINK1 serine peptidase inhibitor, Kazal type 1
SRD5A2 steroid-5-alpha-reductase, alpha polypeptide 2 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 2)
STAB1 stabilin 1
STAB2 stabilin 2
STK11 serine/threonine kinase 11
SYK spleen tyrosine kinase
TACSTD2 tumor-associated calcium signal transducer 2
TBX22 T-box 22
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box)
TGM2 transglutaminase 2
THEM4 thioesterase superfamily member 4
THRB thyroid hormone receptor, beta
TLR2 toll-like receptor 2
TLR4 toll-like receptor 4
TLR9 toll-like receptor 9
TLX1 T-cell leukemia homeobox 1
TMEM18 transmembrane protein 18
TMLHE trimethyllysine hydroxylase, epsilon
TNF tumor necrosis factor
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
TNNI3 troponin I type 3 (cardiac)
TOP2A topoisomerase (DNA) II alpha 170kDa
TP53 tumor protein p53
TP63 tumor protein p63
TPP1 tripeptidyl peptidase I
TRAPPC2 trafficking protein particle complex 2
TRPC2 transient receptor potential cation channel, subfamily C, member 2, pseudogene
TRPM3 transient receptor potential cation channel, subfamily M, member 3
TSHR thyroid stimulating hormone receptor
TYMS thymidylate synthetase
UGT1A1 UDP glucuronosyltransferase 1 family, polypeptide A1
UGT1A10 UDP glucuronosyltransferase 1 family, polypeptide A10
UGT1A7 UDP glucuronosyltransferase 1 family, polypeptide A7
UGT1A8 UDP glucuronosyltransferase 1 family, polypeptide A8
UGT1A9 UDP glucuronosyltransferase 1 family, polypeptide A9
UGT2B7 UDP glucuronosyltransferase 2 family, polypeptide B7
UNC13D unc-13 homolog D (C. elegans)
USH2A Usher syndrome 2A (autosomal recessive, mild)
USP25 ubiquitin specific peptidase 25
VDAC1 voltage-dependent anion channel 1
VEGFA vascular endothelial growth factor A
VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase
VKORC1 vitamin K epoxide reductase complex, subunit 1
VWF von Willebrand factor
WDR62 WD repeat domain 62
WFS1 Wolfram syndrome 1 (wolframin)
WT1 Wilms tumor 1
WWTR1 WW domain containing transcription regulator 1
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase
XPC xeroderma pigmentosum, complementation group C
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)
ZFP36 ZFP36 ring finger protein
ZFP57 ZFP57 zinc finger protein
ZNF420 zinc finger protein 420
ZNF699 zinc finger protein 699