sgk1 Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description serum/glucocorticoid regulated kinase 1|This gene encodes a serine/threonine protein kinase that plays an important role in cellular stress response. This kinase activates certain potassium, sodium, and chloride channels, suggesting an involvement in the regulation of processes such as cell survival, neuronal excitability, and renal sodium excretion. High levels of expression of this gene may contribute to conditions such as hypertension and diabetic nephropathy. Several alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Jan 2009] (NCBI Entrez Gene Database, 6446)
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Genes

64 genes co-occuring with the biological term sgk1 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
AKT1 v-akt murine thymoma viral oncogene homolog 1
ANXA7 annexin A7
AR androgen receptor
BSND barttin CLCNK-type chloride channel accessory beta subunit
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
CHUK conserved helix-loop-helix ubiquitous kinase
CRTC2 CREB regulated transcription coactivator 2
CTGF connective tissue growth factor
CUL1 cullin 1
EGFR epidermal growth factor receptor
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FN1 fibronectin 1
FOXO3 forkhead box O3
GRIN2A glutamate receptor, ionotropic, N-methyl D-aspartate 2A
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B
IGF1 insulin-like growth factor 1 (somatomedin C)
IL2 interleukin 2
KCND3 potassium channel, voltage gated Shal related subfamily D, member 3
KCNIP2 Kv channel interacting protein 2
KCNJ1 potassium channel, inwardly rectifying subfamily J, member 1
MAP2K1 mitogen-activated protein kinase kinase 1
MAP2K2 mitogen-activated protein kinase kinase 2
MAPK1 mitogen-activated protein kinase 1
MAPK3 mitogen-activated protein kinase 3
MAPKAP1 mitogen-activated protein kinase associated protein 1
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MTOR mechanistic target of rapamycin (serine/threonine kinase)
NCSTN nicastrin
NDRG1 N-myc downstream regulated 1
NDRG2 NDRG family member 2
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
NOTCH1 notch 1
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
ORAI1 ORAI calcium release-activated calcium modulator 1
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1
PMM2 phosphomannomutase 2
PPARG peroxisome proliferator-activated receptor gamma
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
RICTOR RPTOR independent companion of MTOR, complex 2
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SCNN1B sodium channel, non voltage gated 1 beta subunit
SGK1 serum/glucocorticoid regulated kinase 1
SGK2 serum/glucocorticoid regulated kinase 2
SGK3 serum/glucocorticoid regulated kinase family, member 3
SLC12A3 solute carrier family 12 (sodium/chloride transporter), member 3
SLC1A2 solute carrier family 1 (glial high affinity glutamate transporter), member 2
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3
SLC1A6 solute carrier family 1 (high affinity aspartate/glutamate transporter), member 6
SLC1A7 solute carrier family 1 (glutamate transporter), member 7
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
SLC2A4 solute carrier family 2 (facilitated glucose transporter), member 4
SLC38A3 solute carrier family 38, member 3
SLC5A1 solute carrier family 5 (sodium/glucose cotransporter), member 1
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8
SLC9A3 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3
SLC9A3R2 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2
TGFB1 transforming growth factor, beta 1
TP53 tumor protein p53
TSC22D3 TSC22 domain family, member 3
VCL vinculin
WNK1 WNK lysine deficient protein kinase 1
WNK3 WNK lysine deficient protein kinase 3
WNK4 WNK lysine deficient protein kinase 4