sh2 domain binding Gene Set

Dataset GO Molecular Function Annotations
Category structural or functional annotations
Type molecular function
Description Interacting selectively and non-covalently with a SH2 domain (Src homology 2) of a protein, a protein domain of about 100 amino-acid residues and belonging to the alpha + beta domain class. (Gene Ontology, GO_0042169)
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30 genes performing the sh2 domain binding molecular function from the curated GO Molecular Function Annotations dataset.

Symbol Name
AFAP1L2 actin filament associated protein 1-like 2
ARHGAP5 Rho GTPase activating protein 5
CRK v-crk avian sarcoma virus CT10 oncogene homolog
CTR9 CTR9, Paf1/RNA polymerase II complex component
DAG1 dystroglycan 1 (dystrophin-associated glycoprotein 1)
DLC1 DLC1 Rho GTPase activating protein
GNB2L1 guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1
INPPL1 inositol polyphosphate phosphatase-like 1
IRS1 insulin receptor substrate 1
JAK2 Janus kinase 2
KHDRBS2 KH domain containing, RNA binding, signal transduction associated 2
LAT2 linker for activation of T cells family, member 2
LAX1 lymphocyte transmembrane adaptor 1
LCK LCK proto-oncogene, Src family tyrosine kinase
LILRB1 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1
MS4A2 membrane-spanning 4-domains, subfamily A, member 2
NLK nemo-like kinase
NUP62 nucleoporin 62kDa
PAG1 phosphoprotein membrane anchor with glycosphingolipid microdomains 1
PTK2 protein tyrosine kinase 2
PTPN6 protein tyrosine phosphatase, non-receptor type 6
SH3PXD2B SH3 and PX domains 2B
SHCBP1 SHC SH2-domain binding protein 1
SIT1 signaling threshold regulating transmembrane adaptor 1
SKAP1 src kinase associated phosphoprotein 1
SQSTM1 sequestosome 1
SRC SRC proto-oncogene, non-receptor tyrosine kinase
SYNGR3 synaptogyrin 3
SYP synaptophysin
TRPV4 transient receptor potential cation channel, subfamily V, member 4