shoc2 Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description soc-2 suppressor of clear homolog (C. elegans)|This gene encodes a protein that consists almost entirely of leucine-rich repeats, a domain implicated in protein-protein interactions. The protein may function as a scaffold linking RAS to downstream signal transducers in the RAS/ERK MAP kinase signaling cascade. Mutations in this gene have been associated with Noonan-like syndrome with loose anagen hair. [provided by RefSeq, May 2010] (NCBI Entrez Gene Database, 8036)
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Genes

8 genes co-occuring with the biological term shoc2 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase
MAPK1 mitogen-activated protein kinase 1
MAPK3 mitogen-activated protein kinase 3
MRAS muscle RAS oncogene homolog
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
SCRIB scribbled planar cell polarity protein
SHOC2 soc-2 suppressor of clear homolog (C. elegans)