siah2 Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description siah E3 ubiquitin protein ligase 2|This gene encodes a protein that is a member of the seven in absentia homolog (SIAH) family. The protein is an E3 ligase and is involved in ubiquitination and proteasome-mediated degradation of specific proteins. The activity of this ubiquitin ligase has been implicated in regulating cellular response to hypoxia. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 6478)
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Genes

24 genes co-occuring with the biological term siah2 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
AFF1 AF4/FMR2 family, member 1
AR androgen receptor
CEBPD CCAAT/enhancer binding protein (C/EBP), delta
EGLN3 egl-9 family hypoxia-inducible factor 3
FOXA2 forkhead box A2
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
KEAP1 kelch-like ECH-associated protein 1
KMT2A lysine (K)-specific methyltransferase 2A
NCOR1 nuclear receptor corepressor 1
NFE2L2 nuclear factor, erythroid 2-like 2
SH3RF1 SH3 domain containing ring finger 1
SIAH1 siah E3 ubiquitin protein ligase 1
SIAH2 siah E3 ubiquitin protein ligase 2
SKI SKI proto-oncogene
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SRC SRC proto-oncogene, non-receptor tyrosine kinase
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
TINF2 TERF1 (TRF1)-interacting nuclear factor 2
TP53 tumor protein p53
TP53BP2 tumor protein p53 binding protein 2
TPX2 TPX2, microtubule-associated
TYK2 tyrosine kinase 2
USP13 ubiquitin specific peptidase 13 (isopeptidase T-3)
USP19 ubiquitin specific peptidase 19