signal recognition particle receptor complex Gene Set

Dataset COMPARTMENTS Text-mining Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description A transmembrane heterodimeric protein located in the membrane of the rough endoplasmic reticulum. Both subunits contain GTPase domains with which signal recognition particle interacts. In the presence of GTP and SRP receptor, SRP is released from the ribosome-nascent chain complex. (Gene Ontology, GO_0005785)
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86 proteins co-occuring with the signal recognition particle receptor complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
GAB2 GRB2-associated binding protein 2 1.72682
A1BG alpha-1-B glycoprotein 1.61706
IRS1 insulin receptor substrate 1 1.46665
GAB3 GRB2-associated binding protein 3 1.39517
IRS2 insulin receptor substrate 2 1.31142
GRB2 growth factor receptor-bound protein 2 1.28516
FRS2 fibroblast growth factor receptor substrate 2 1.25917
SHC3 SHC (Src homology 2 domain containing) transforming protein 3 1.24498
INSR insulin receptor 1.20963
IRS4 insulin receptor substrate 4 1.19057
SRPX sushi-repeat containing protein, X-linked 1.12552
PTPN11 protein tyrosine phosphatase, non-receptor type 11 1.00399
FGF20 fibroblast growth factor 20 0.93596
SPRY4 sprouty homolog 4 (Drosophila) 0.915776
SHC1 SHC (Src homology 2 domain containing) transforming protein 1 0.909251
SRC SRC proto-oncogene, non-receptor tyrosine kinase 0.905996
CRK v-crk avian sarcoma virus CT10 oncogene homolog 0.865367
DOK2 docking protein 2, 56kDa 0.86077
GAB1 GRB2-associated binding protein 1 0.838269
SRPR signal recognition particle receptor (docking protein) 0.767715
EFS embryonal Fyn-associated substrate 0.740064
DOK5 docking protein 5 0.738713
SHC2 SHC (Src homology 2 domain containing) transforming protein 2 0.69427
INS insulin 0.673762
DOK4 docking protein 4 0.666827
SRP54 signal recognition particle 54kDa 0.633732
NEDD9 neural precursor cell expressed, developmentally down-regulated 9 0.630745
PEX14 peroxisomal biogenesis factor 14 0.605706
DOK3 docking protein 3 0.577581
SHC4 SHC (Src homology 2 domain containing) family, member 4 0.567585
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.550186
PTS 6-pyruvoyltetrahydropterin synthase 0.539472
IGF1 insulin-like growth factor 1 (somatomedin C) 0.536183
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase 0.521023
SEC61A1 Sec61 alpha 1 subunit (S. cerevisiae) 0.499042
FGF1 fibroblast growth factor 1 (acidic) 0.483273
TRA2B transformer 2 beta homolog (Drosophila) 0.463198
MAPKAPK5 mitogen-activated protein kinase-activated protein kinase 5 0.462398
MET MET proto-oncogene, receptor tyrosine kinase 0.461599
PEX11B peroxisomal biogenesis factor 11 beta 0.452825
DOK1 docking protein 1, 62kDa (downstream of tyrosine kinase 1) 0.447656
IGF1R insulin-like growth factor 1 receptor 0.4425
ARHGAP32 Rho GTPase activating protein 32 0.438937
ZNF384 zinc finger protein 384 0.434591
SNPH syntaphilin 0.432224
RASA1 RAS p21 protein activator (GTPase activating protein) 1 0.432224
CDO1 cysteine dioxygenase type 1 0.420428
FGFR2 fibroblast growth factor receptor 2 0.420036
SRSF9 serine/arginine-rich splicing factor 9 0.415728
COLEC12 collectin sub-family member 12 0.402859
MUSK muscle, skeletal, receptor tyrosine kinase 0.395098
CDK20 cyclin-dependent kinase 20 0.377354
CNTFR ciliary neurotrophic factor receptor 0.332472
RND1 Rho family GTPase 1 0.32345
SLC25A17 solute carrier family 25 (mitochondrial carrier; peroxisomal membrane protein, 34kDa), member 17 0.318205
NUMBL numb homolog (Drosophila)-like 0.307749
EFNA2 ephrin-A2 0.304771
CDON cell adhesion associated, oncogene regulated 0.301797
PTPN3 protein tyrosine phosphatase, non-receptor type 3 0.301054
FYB FYN binding protein 0.292897
TYRO3 TYRO3 protein tyrosine kinase 0.27998
KLF2 Kruppel-like factor 2 0.255834
BDNF brain-derived neurotrophic factor 0.24424
SOS1 son of sevenless homolog 1 (Drosophila) 0.243879
PLEK pleckstrin 0.243519
PI3 peptidase inhibitor 3, skin-derived 0.240996
CRKL v-crk avian sarcoma virus CT10 oncogene homolog-like 0.235966
MARK3 MAP/microtubule affinity-regulating kinase 3 0.225976
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon 0.224204
MAPK11 mitogen-activated protein kinase 11 0.219969
PTPN6 protein tyrosine phosphatase, non-receptor type 6 0.215063
ALK anaplastic lymphoma receptor tyrosine kinase 0.214366
SRRM2 serine/arginine repetitive matrix 2 0.21124
RET ret proto-oncogene 0.208137
POLDIP3 polymerase (DNA-directed), delta interacting protein 3 0.20574
ADAMTS2 ADAM metallopeptidase with thrombospondin type 1 motif, 2 0.201672
RAPGEF1 Rap guanine nucleotide exchange factor (GEF) 1 0.197662
LIFR leukemia inhibitory factor receptor alpha 0.195353
EIF3A eukaryotic translation initiation factor 3, subunit A 0.193719
HSPA1B heat shock 70kDa protein 1B 0.192423
EGFR epidermal growth factor receptor 0.188905
ERBB2 erb-b2 receptor tyrosine kinase 2 0.184853
FGFR4 fibroblast growth factor receptor 4 0.172201
EVPL envoplakin 0.16233
LAT linker for activation of T cells 0.158315
EPHA2 EPH receptor A2 0.156863