signaling adaptor activity Gene Set

Dataset GO Molecular Function Annotations 2015
Category structural or functional annotations
Type molecular function
Description The binding activity of a molecule that brings together two or more molecules in a signaling pathway, permitting those molecules to function in a coordinated way. Adaptor molecules themselves do not have catalytic activity. (Gene Ontology, GO_0035591)
External Link http://amigo.geneontology.org/amigo/term/GO:0035591
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Genes

71 genes performing the signaling adaptor activity molecular function from the curated GO Molecular Function Annotations 2015 dataset.

Symbol Name
AFAP1L2 actin filament associated protein 1-like 2
ARHGAP1 Rho GTPase activating protein 1
ARHGAP4 Rho GTPase activating protein 4
ARHGAP6 Rho GTPase activating protein 6
BLNK B-cell linker
CD28 CD28 molecule
CHN1 chimerin 1
CHN2 chimerin 2
CLNK cytokine-dependent hematopoietic cell linker
CNTNAP1 contactin associated protein 1
CRK v-crk avian sarcoma virus CT10 oncogene homolog
CRKL v-crk avian sarcoma virus CT10 oncogene homolog-like
DAB2IP DAB2 interacting protein
DOK2 docking protein 2, 56kDa
DUSP19 dual specificity phosphatase 19
EPS8 epidermal growth factor receptor pathway substrate 8
FCRL2 Fc receptor-like 2
FRS2 fibroblast growth factor receptor substrate 2
GAB1 GRB2-associated binding protein 1
GAB2 GRB2-associated binding protein 2
GNB2L1 guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1
GRAP GRB2-related adaptor protein
GRAP2 GRB2-related adaptor protein 2
GRB10 growth factor receptor-bound protein 10
GRB14 growth factor receptor-bound protein 14
GRB2 growth factor receptor-bound protein 2
GRB7 growth factor receptor-bound protein 7
HOMER1 homer scaffolding protein 1
HSH2D hematopoietic SH2 domain containing
IRS1 insulin receptor substrate 1
IRS4 insulin receptor substrate 4
ITSN2 intersectin 2
KHDRBS1 KH domain containing, RNA binding, signal transduction associated 1
KSR1 kinase suppressor of ras 1
LASP1 LIM and SH3 protein 1
LAT linker for activation of T cells
LDLRAP1 low density lipoprotein receptor adaptor protein 1
MAPK8IP1 mitogen-activated protein kinase 8 interacting protein 1
MAPK8IP2 mitogen-activated protein kinase 8 interacting protein 2
MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3
MPP7 membrane protein, palmitoylated 7 (MAGUK p55 subfamily member 7)
NCK1 NCK adaptor protein 1
NCK2 NCK adaptor protein 2
PAG1 phosphoprotein membrane anchor with glycosphingolipid microdomains 1
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PTPN11 protein tyrosine phosphatase, non-receptor type 11
RUSC1 RUN and SH3 domain containing 1
SH2B2 SH2B adaptor protein 2
SH2D1A SH2 domain containing 1A
SH2D2A SH2 domain containing 2A
SH2D3A SH2 domain containing 3A
SH2D3C SH2 domain containing 3C
SH3BGR SH3 domain binding glutamate-rich protein
SH3BGRL SH3 domain binding glutamate-rich protein like
SH3BP2 SH3-domain binding protein 2
SHB Src homology 2 domain containing adaptor protein B
SHC1 SHC (Src homology 2 domain containing) transforming protein 1
SKAP1 src kinase associated phosphoprotein 1
SKAP2 src kinase associated phosphoprotein 2
SLA Src-like-adaptor
SLA2 Src-like-adaptor 2
SOCS2 suppressor of cytokine signaling 2
SORBS1 sorbin and SH3 domain containing 1
SPAG9 sperm associated antigen 9
SRC SRC proto-oncogene, non-receptor tyrosine kinase
STAM signal transducing adaptor molecule (SH3 domain and ITAM motif) 1
STAP1 signal transducing adaptor family member 1
TOB1 transducer of ERBB2, 1
TP53BP2 tumor protein p53 binding protein 2
TRAT1 T cell receptor associated transmembrane adaptor 1
VAV3 vav 3 guanine nucleotide exchange factor