signalregulated Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Similar Terms
Downloads & Tools

Genes

261 genes co-occuring with the biological term signalregulated in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ACE2 angiotensin I converting enzyme 2
ADAM28 ADAM metallopeptidase domain 28
ADAMTS4 ADAM metallopeptidase with thrombospondin type 1 motif, 4
ADCYAP1 adenylate cyclase activating polypeptide 1 (pituitary)
ADGRE5 adhesion G protein-coupled receptor E5
ADM2 adrenomedullin 2
AGTR1 angiotensin II receptor, type 1
AHR aryl hydrocarbon receptor
AKT1 v-akt murine thymoma viral oncogene homolog 1
ALOX12 arachidonate 12-lipoxygenase
ANO1 anoctamin 1, calcium activated chloride channel
APP amyloid beta (A4) precursor protein
AQP5 aquaporin 5
ARRB1 arrestin, beta 1
ARRB2 arrestin, beta 2
ATF3 activating transcription factor 3
ATR ATR serine/threonine kinase
BAD BCL2-associated agonist of cell death
BAIAP2L1 BAI1-associated protein 2-like 1
BCL2L1 BCL2-like 1
BCL2L11 BCL2-like 11 (apoptosis facilitator)
BMP2 bone morphogenetic protein 2
BMP4 bone morphogenetic protein 4
BRAF B-Raf proto-oncogene, serine/threonine kinase
C1QTNF3 C1q and tumor necrosis factor related protein 3
C3 complement component 3
C5 complement component 5
CAPN1 calpain 1, (mu/I) large subunit
CARD9 caspase recruitment domain family, member 9
CCL13 chemokine (C-C motif) ligand 13
CD28 CD28 molecule
CD40 CD40 molecule, TNF receptor superfamily member 5
CD40LG CD40 ligand
CD44 CD44 molecule (Indian blood group)
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain
CD86 CD86 molecule
CD9 CD9 molecule
CDCA7L cell division cycle associated 7-like
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDH5 cadherin 5, type 2 (vascular endothelium)
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CEBPB CCAAT/enhancer binding protein (C/EBP), beta
CHGA chromogranin A
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CIRBP cold inducible RNA binding protein
CLDN4 claudin 4
CLEC7A C-type lectin domain family 7, member A
CLIC4 chloride intracellular channel 4
COL1A1 collagen, type I, alpha 1
CRP C-reactive protein, pentraxin-related
CSF1 colony stimulating factor 1 (macrophage)
CSF3 colony stimulating factor 3 (granulocyte)
CTSK cathepsin K
CXCL12 chemokine (C-X-C motif) ligand 12
CXCL8 chemokine (C-X-C motif) ligand 8
CXCR4 chemokine (C-X-C motif) receptor 4
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
DUSP1 dual specificity phosphatase 1
DUSP10 dual specificity phosphatase 10
DUSP26 dual specificity phosphatase 26 (putative)
DUSP3 dual specificity phosphatase 3
DUSP4 dual specificity phosphatase 4
DUSP6 dual specificity phosphatase 6
EDN1 endothelin 1
EEF2K eukaryotic elongation factor 2 kinase
EGF epidermal growth factor
EGFR epidermal growth factor receptor
EGR1 early growth response 1
EIF3J eukaryotic translation initiation factor 3, subunit J
ELK1 ELK1, member of ETS oncogene family
EPHA2 EPH receptor A2
EPHB2 EPH receptor B2
ERBB2 erb-b2 receptor tyrosine kinase 2
ERBB3 erb-b2 receptor tyrosine kinase 3
ESR1 estrogen receptor 1
EXOC7 exocyst complex component 7
F2R coagulation factor II (thrombin) receptor
F3 coagulation factor III (thromboplastin, tissue factor)
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FHL1 four and a half LIM domains 1
FLNA filamin A, alpha
FLT3 fms-related tyrosine kinase 3
FOS FBJ murine osteosarcoma viral oncogene homolog
FOXO1 forkhead box O1
FPR1 formyl peptide receptor 1
FPR2 formyl peptide receptor 2
GAB1 GRB2-associated binding protein 1
GAREM GRB2 associated, regulator of MAPK1
GCM1 glial cells missing homolog 1 (Drosophila)
GDNF glial cell derived neurotrophic factor
GHRL ghrelin/obestatin prepropeptide
GNAO1 guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
GNAS GNAS complex locus
GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1
GPHN gephyrin
GPR55 G protein-coupled receptor 55
GREM1 gremlin 1, DAN family BMP antagonist
GRIN1 glutamate receptor, ionotropic, N-methyl D-aspartate 1
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B
GSK3B glycogen synthase kinase 3 beta
GSTP1 glutathione S-transferase pi 1
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HLA-G major histocompatibility complex, class I, G
HMOX1 heme oxygenase 1
HPSE heparanase
HRAS Harvey rat sarcoma viral oncogene homolog
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
HSPA9 heat shock 70kDa protein 9 (mortalin)
HSPB1 heat shock 27kDa protein 1
HSPB2 heat shock 27kDa protein 2
HTR2C 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled
HTR4 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled
HTR7 5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled
IFI44 interferon-induced protein 44
IGF1 insulin-like growth factor 1 (somatomedin C)
IL2 interleukin 2
IL20 interleukin 20
IL4 interleukin 4
IL5 interleukin 5
IL6 interleukin 6
IL6R interleukin 6 receptor
IL6ST interleukin 6 signal transducer
IL9 interleukin 9
ILK integrin-linked kinase
INS insulin
IRS1 insulin receptor substrate 1
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
ITGB1BP1 integrin beta 1 binding protein 1
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
JAK1 Janus kinase 1
JUN jun proto-oncogene
KHDRBS1 KH domain containing, RNA binding, signal transduction associated 1
KIAA1524 KIAA1524
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KMT2A lysine (K)-specific methyltransferase 2A
KNDC1 kinase non-catalytic C-lobe domain (KIND) containing 1
KRAS Kirsten rat sarcoma viral oncogene homolog
L1CAM L1 cell adhesion molecule
LAG3 lymphocyte-activation gene 3
LPAR1 lysophosphatidic acid receptor 1
LPAR2 lysophosphatidic acid receptor 2
LPAR3 lysophosphatidic acid receptor 3
LRP1 low density lipoprotein receptor-related protein 1
LRRC4 leucine rich repeat containing 4
MAP2K1 mitogen-activated protein kinase kinase 1
MAP2K7 mitogen-activated protein kinase kinase 7
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MAP3K11 mitogen-activated protein kinase kinase kinase 11
MAPK1 mitogen-activated protein kinase 1
MAPK14 mitogen-activated protein kinase 14
MAPK15 mitogen-activated protein kinase 15
MAPK3 mitogen-activated protein kinase 3
MAPK6 mitogen-activated protein kinase 6
MAPK7 mitogen-activated protein kinase 7
MAPK8 mitogen-activated protein kinase 8
MAPT microtubule-associated protein tau
MCL1 myeloid cell leukemia 1
MET MET proto-oncogene, receptor tyrosine kinase
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor)
MIR199A1 microRNA 199a-1
MIR205 microRNA 205
MIR7-1 microRNA 7-1
MIR7-2 microRNA 7-2
MIR7-3 microRNA 7-3
MME membrane metallo-endopeptidase
MMP1 matrix metallopeptidase 1
MMP13 matrix metallopeptidase 13
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MMP2 matrix metallopeptidase 2
MMP9 matrix metallopeptidase 9
MSLN mesothelin
MT3 metallothionein 3
MTNR1A melatonin receptor 1A
MUC1 mucin 1, cell surface associated
MUC15 mucin 15, cell surface associated
MUC5B mucin 5B, oligomeric mucus/gel-forming
NF2 neurofibromin 2 (merlin)
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NPPA natriuretic peptide A
NR1I3 nuclear receptor subfamily 1, group I, member 3
NR3C2 nuclear receptor subfamily 3, group C, member 2
NR4A1 nuclear receptor subfamily 4, group A, member 1
NRG1 neuregulin 1
NUDC nudC nuclear distribution protein
OPRD1 opioid receptor, delta 1
OSBP oxysterol binding protein
P2RX1 purinergic receptor P2X, ligand gated ion channel, 1
P2RY2 purinergic receptor P2Y, G-protein coupled, 2
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor)
PEA15 phosphoprotein enriched in astrocytes 15
PF4 platelet factor 4
PF4V1 platelet factor 4 variant 1
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1
PLAU plasminogen activator, urokinase
PLD1 phospholipase D1, phosphatidylcholine-specific
PLP1 proteolipid protein 1
PML promyelocytic leukemia
POU2F3 POU class 2 homeobox 3
PPARG peroxisome proliferator-activated receptor gamma
PPM1F protein phosphatase, Mg2+/Mn2+ dependent, 1F
PPP1CA protein phosphatase 1, catalytic subunit, alpha isozyme
PRDM2 PR domain containing 2, with ZNF domain
PRKCA protein kinase C, alpha
PRKCD protein kinase C, delta
PRL prolactin
PROM1 prominin 1
PTAFR platelet-activating factor receptor
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTK2 protein tyrosine kinase 2
PTN pleiotrophin
PTPN11 protein tyrosine phosphatase, non-receptor type 11
PTPN12 protein tyrosine phosphatase, non-receptor type 12
PTX3 pentraxin 3, long
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
RAP1GAP RAP1 GTPase activating protein
RAPGEF3 Rap guanine nucleotide exchange factor (GEF) 3
RARA retinoic acid receptor, alpha
RASGRF1 Ras protein-specific guanine nucleotide-releasing factor 1
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
RET ret proto-oncogene
RGS2 regulator of G-protein signaling 2
RHO rhodopsin
RORA RAR-related orphan receptor A
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1
S100A4 S100 calcium binding protein A4
S1PR3 sphingosine-1-phosphate receptor 3
SAA1 serum amyloid A1
SCNN1A sodium channel, non voltage gated 1 alpha subunit
SIRPA signal-regulatory protein alpha
SIRPB2 signal-regulatory protein beta 2
SIRT1 sirtuin 1
SIRT2 sirtuin 2
SMAD1 SMAD family member 1
SP3 Sp3 transcription factor
SPAG1 sperm associated antigen 1
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
SPRY2 sprouty homolog 2 (Drosophila)
SRC SRC proto-oncogene, non-receptor tyrosine kinase
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced
SYNE2 spectrin repeat containing, nuclear envelope 2
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TGFB1 transforming growth factor, beta 1
THBD thrombomodulin
TIMP1 TIMP metallopeptidase inhibitor 1
TLR2 toll-like receptor 2
TNF tumor necrosis factor
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9
TRAF2 TNF receptor-associated factor 2
TREM1 triggering receptor expressed on myeloid cells 1
TRPC3 transient receptor potential cation channel, subfamily C, member 3
TRPC6 transient receptor potential cation channel, subfamily C, member 6
TTN titin
UTS2 urotensin 2
VTN vitronectin
ZC3HC1 zinc finger, C3HC-type containing 1
ZG16B zymogen granule protein 16B