significance Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Similar Terms
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Genes

738 genes co-occuring with the biological term significance in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
A3GALT2 alpha 1,3-galactosyltransferase 2
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
ABCA4 ATP-binding cassette, sub-family A (ABC1), member 4
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group)
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
ACADM acyl-CoA dehydrogenase, C-4 to C-12 straight chain
ACE angiotensin I converting enzyme
ACHE acetylcholinesterase (Yt blood group)
ACKR2 atypical chemokine receptor 2
ACP1 acid phosphatase 1, soluble
ACP5 acid phosphatase 5, tartrate resistant
ADAMTS4 ADAM metallopeptidase with thrombospondin type 1 motif, 4
ADD1 adducin 1 (alpha)
ADH1C alcohol dehydrogenase 1C (class I), gamma polypeptide
ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide
ADIPOQ adiponectin, C1Q and collagen domain containing
ADM adrenomedullin
ADRA2B adrenoceptor alpha 2B
AGR2 anterior gradient 2
AGTR1 angiotensin II receptor, type 1
AIP aryl hydrocarbon receptor interacting protein
AKAP10 A kinase (PRKA) anchor protein 10
AKT1 v-akt murine thymoma viral oncogene homolog 1
ALB albumin
ALCAM activated leukocyte cell adhesion molecule
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
AMH anti-Mullerian hormone
AMPD1 adenosine monophosphate deaminase 1
ANXA10 annexin A10
ANXA2 annexin A2
ANXA3 annexin A3
ANXA7 annexin A7
APC adenomatous polyposis coli
APCS amyloid P component, serum
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1
API5 apoptosis inhibitor 5
APOA1 apolipoprotein A-I
APOC1 apolipoprotein C-I
APOE apolipoprotein E
APOH apolipoprotein H (beta-2-glycoprotein I)
APP amyloid beta (A4) precursor protein
AQP4 aquaporin 4
AR androgen receptor
ARHGAP10 Rho GTPase activating protein 10
ARID1A AT rich interactive domain 1A (SWI-like)
ARNTL aryl hydrocarbon receptor nuclear translocator-like
ARSG arylsulfatase G
ASPN asporin
ATG16L1 autophagy related 16-like 1 (S. cerevisiae)
ATM ATM serine/threonine kinase
ATP6V0E1 ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1
ATP6V1E1 ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E1
ATXN2 ataxin 2
ATXN3 ataxin 3
AURKA aurora kinase A
AURKB aurora kinase B
AURKC aurora kinase C
AUTS2 autism susceptibility candidate 2
B4GALT2 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2
BACE1 beta-site APP-cleaving enzyme 1
BAX BCL2-associated X protein
BCL2 B-cell CLL/lymphoma 2
BCL2L13 BCL2-like 13 (apoptosis facilitator)
BCR breakpoint cluster region
BDNF brain-derived neurotrophic factor
BECN1 beclin 1, autophagy related
BIK BCL2-interacting killer (apoptosis-inducing)
BIRC5 baculoviral IAP repeat containing 5
BIRC7 baculoviral IAP repeat containing 7
BLM Bloom syndrome, RecQ helicase-like
BMP2 bone morphogenetic protein 2
BMP4 bone morphogenetic protein 4
BMPR1A bone morphogenetic protein receptor, type IA
BNIPL BCL2/adenovirus E1B 19kD interacting protein like
BRAF B-Raf proto-oncogene, serine/threonine kinase
BRCA1 breast cancer 1, early onset
BRCA2 breast cancer 2, early onset
BROX BRO1 domain and CAAX motif containing
BST1 bone marrow stromal cell antigen 1
BUB1 BUB1 mitotic checkpoint serine/threonine kinase
C1QTNF7 C1q and tumor necrosis factor related protein 7
C3 complement component 3
C4A complement component 4A (Rodgers blood group)
C4B complement component 4B (Chido blood group)
C4BPA complement component 4 binding protein, alpha
C9ORF72 chromosome 9 open reading frame 72
CA9 carbonic anhydrase IX
CALB2 calbindin 2
CALCA calcitonin-related polypeptide alpha
CAMSAP2 calmodulin regulated spectrin-associated protein family, member 2
CASP14 caspase 14, apoptosis-related cysteine peptidase
CASP3 caspase 3, apoptosis-related cysteine peptidase
CASP5 caspase 5, apoptosis-related cysteine peptidase
CASP8AP2 caspase 8 associated protein 2
CCKAR cholecystokinin A receptor
CCKBR cholecystokinin B receptor
CCL2 chemokine (C-C motif) ligand 2
CCL3 chemokine (C-C motif) ligand 3
CCL5 chemokine (C-C motif) ligand 5
CCNB2 cyclin B2
CCND1 cyclin D1
CCNE1 cyclin E1
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene)
CD14 CD14 molecule
CD151 CD151 molecule (Raph blood group)
CD19 CD19 molecule
CD209 CD209 molecule
CD27 CD27 molecule
CD38 CD38 molecule
CD44 CD44 molecule (Indian blood group)
CD5 CD5 molecule
CD79A CD79a molecule, immunoglobulin-associated alpha
CD83 CD83 molecule
CD99 CD99 molecule
CDC42 cell division cycle 42
CDC73 cell division cycle 73
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast)
CDH13 cadherin 13
CDH2 cadherin 2, type 1, N-cadherin (neuronal)
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CDKN2A cyclin-dependent kinase inhibitor 2A
CDKN2B cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
CDX2 caudal type homeobox 2
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CEBPB CCAAT/enhancer binding protein (C/EBP), beta
CENPI centromere protein I
CFLAR CASP8 and FADD-like apoptosis regulator
CFP complement factor properdin
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
CHEK2 checkpoint kinase 2
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CHKA choline kinase alpha
CHRNA7 cholinergic receptor, nicotinic, alpha 7 (neuronal)
CISD2 CDGSH iron sulfur domain 2
CLCN1 chloride channel, voltage-sensitive 1
CLCN7 chloride channel, voltage-sensitive 7
CLDN1 claudin 1
CLDN18 claudin 18
CLDN2 claudin 2
CLDN7 claudin 7
CLOCK clock circadian regulator
CNTNAP2 contactin associated protein-like 2
COL18A1 collagen, type XVIII, alpha 1
COL1A1 collagen, type I, alpha 1
COMMD1 copper metabolism (Murr1) domain containing 1
COMMD6 COMM domain containing 6
COMT catechol-O-methyltransferase
CR1 complement component (3b/4b) receptor 1 (Knops blood group)
CRLF2 cytokine receptor-like factor 2
CRP C-reactive protein, pentraxin-related
CRY1 cryptochrome circadian clock 1
CRYZ crystallin, zeta (quinone reductase)
CSK c-src tyrosine kinase
CSNK2A1 casein kinase 2, alpha 1 polypeptide
CTDSPL CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like
CTGF connective tissue growth factor
CTLA4 cytotoxic T-lymphocyte-associated protein 4
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CTNNBIP1 catenin, beta interacting protein 1
CTSB cathepsin B
CTSD cathepsin D
CTSL cathepsin L
CXCL12 chemokine (C-X-C motif) ligand 12
CXCL8 chemokine (C-X-C motif) ligand 8
CXCR4 chemokine (C-X-C motif) receptor 4
CXCR6 chemokine (C-X-C motif) receptor 6
CYBA cytochrome b-245, alpha polypeptide
CYP11B2 cytochrome P450, family 11, subfamily B, polypeptide 2
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
CYP24A1 cytochrome P450, family 24, subfamily A, polypeptide 1
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19
CYP2C8 cytochrome P450, family 2, subfamily C, polypeptide 8
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4
CYP4V2 cytochrome P450, family 4, subfamily V, polypeptide 2
CYR61 cysteine-rich, angiogenic inducer, 61
DACH1 dachshund family transcription factor 1
DAP3 death associated protein 3
DAXX death-domain associated protein
DCC DCC netrin 1 receptor
DCPS decapping enzyme, scavenger
DCTN1 dynactin 1
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6
DIABLO diablo, IAP-binding mitochondrial protein
DIO3 deiodinase, iodothyronine, type III
DISC1 disrupted in schizophrenia 1
DKK1 dickkopf WNT signaling pathway inhibitor 1
DKK2 dickkopf WNT signaling pathway inhibitor 2
DKK3 dickkopf WNT signaling pathway inhibitor 3
DNMBP dynamin binding protein
DPYD dihydropyrimidine dehydrogenase
DRD2 dopamine receptor D2
DRD4 dopamine receptor D4
DYNLT1 dynein, light chain, Tctex-type 1
E2F1 E2F transcription factor 1
EDA ectodysplasin A
EDAR ectodysplasin A receptor
EDN1 endothelin 1
EGFR epidermal growth factor receptor
EGLN3 egl-9 family hypoxia-inducible factor 3
EGR1 early growth response 1
EHMT1 euchromatic histone-lysine N-methyltransferase 1
EI24 etoposide induced 2.4
EIF4A1 eukaryotic translation initiation factor 4A1
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1
ELAC2 elaC ribonuclease Z 2
ELAVL1 ELAV like RNA binding protein 1
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific )
ENG endoglin
ENO2 enolase 2 (gamma, neuronal)
EPHB6 EPH receptor B6
EPOR erythropoietin receptor
ERBB2 erb-b2 receptor tyrosine kinase 2
ERBB3 erb-b2 receptor tyrosine kinase 3
ERBB4 erb-b2 receptor tyrosine kinase 4
ERCC1 excision repair cross-complementation group 1
ERCC2 excision repair cross-complementation group 2
ESD esterase D
ESR1 estrogen receptor 1
ESR2 estrogen receptor 2 (ER beta)
ESRP1 epithelial splicing regulatory protein 1
EYA1 EYA transcriptional coactivator and phosphatase 1
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit
F11R F11 receptor
F13A1 coagulation factor XIII, A1 polypeptide
F7 coagulation factor VII (serum prothrombin conversion accelerator)
F8 coagulation factor VIII, procoagulant component
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FABP7 fatty acid binding protein 7, brain
FAF1 Fas (TNFRSF6) associated factor 1
FAM162A family with sequence similarity 162, member A
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FCER2 Fc fragment of IgE, low affinity II, receptor for (CD23)
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32)
FFAR4 free fatty acid receptor 4
FGB fibrinogen beta chain
FGF2 fibroblast growth factor 2 (basic)
FGFR2 fibroblast growth factor receptor 2
FGFR4 fibroblast growth factor receptor 4
FGL2 fibrinogen-like 2
FHIT fragile histidine triad
FLT3 fms-related tyrosine kinase 3
FN1 fibronectin 1
FOXA1 forkhead box A1
FOXA2 forkhead box A2
FOXP1 forkhead box P1
FOXP3 forkhead box P3
FSHB follicle stimulating hormone, beta polypeptide
FSHR follicle stimulating hormone receptor
FZD3 frizzled class receptor 3
GATA3 GATA binding protein 3
GC group-specific component (vitamin D binding protein)
GCSAM germinal center-associated, signaling and motility
GDA guanine deaminase
GDE1 glycerophosphodiester phosphodiesterase 1
GDF5 growth differentiation factor 5
GGPS1 geranylgeranyl diphosphate synthase 1
GHR growth hormone receptor
GHRHR growth hormone releasing hormone receptor
GHRL ghrelin/obestatin prepropeptide
GHSR growth hormone secretagogue receptor
GJB2 gap junction protein, beta 2, 26kDa
GLI3 GLI family zinc finger 3
GLO1 glyoxalase I
GNAS GNAS complex locus
GNB2L1 guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1
GNB3 guanine nucleotide binding protein (G protein), beta polypeptide 3
GOLPH3 golgi phosphoprotein 3 (coat-protein)
GOT1 glutamic-oxaloacetic transaminase 1, soluble
GPSM1 G-protein signaling modulator 1
GRIK3 glutamate receptor, ionotropic, kainate 3
GRIN2A glutamate receptor, ionotropic, N-methyl D-aspartate 2A
GRM7 glutamate receptor, metabotropic 7
GRN granulin
GSTA1 glutathione S-transferase alpha 1
GSTA2 glutathione S-transferase alpha 2
GSTM1 glutathione S-transferase mu 1
GSTP1 glutathione S-transferase pi 1
GSTT1 glutathione S-transferase theta 1
H2AFX H2A histone family, member X
HBA1 hemoglobin, alpha 1
HBEGF heparin-binding EGF-like growth factor
HDAC1 histone deacetylase 1
HDAC6 histone deacetylase 6
HFE hemochromatosis
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HK1 hexokinase 1
HK2 hexokinase 2
HLA-A major histocompatibility complex, class I, A
HLA-B major histocompatibility complex, class I, B
HLA-C major histocompatibility complex, class I, C
HLA-DPB1 major histocompatibility complex, class II, DP beta 1
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HLA-G major histocompatibility complex, class I, G
HMG20A high mobility group 20A
HMGA1 high mobility group AT-hook 1
HMGA2 high mobility group AT-hook 2
HMGB1 high mobility group box 1
HMMR hyaluronan-mediated motility receptor (RHAMM)
HMOX1 heme oxygenase 1
HNF1A HNF1 homeobox A
HNF4A hepatocyte nuclear factor 4, alpha
HOXD9 homeobox D9
HP haptoglobin
HPSE heparanase
HSD17B1 hydroxysteroid (17-beta) dehydrogenase 1
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
HSPB8 heat shock 22kDa protein 8
HSPD1 heat shock 60kDa protein 1 (chaperonin)
ICAM1 intercellular adhesion molecule 1
ICAM4 intercellular adhesion molecule 4 (Landsteiner-Wiener blood group)
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble
IDO1 indoleamine 2,3-dioxygenase 1
IFIH1 interferon induced with helicase C domain 1
IFNAR1 interferon (alpha, beta and omega) receptor 1
IFNG interferon, gamma
IGF1 insulin-like growth factor 1 (somatomedin C)
IGF1R insulin-like growth factor 1 receptor
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
IGFBP3 insulin-like growth factor binding protein 3
IGH immunoglobulin heavy locus
IGHE immunoglobulin heavy constant epsilon
IGHV3-21 immunoglobulin heavy variable 3-21
IKZF1 IKAROS family zinc finger 1 (Ikaros)
IL10 interleukin 10
IL11 interleukin 11
IL17A interleukin 17A
IL17RA interleukin 17 receptor A
IL18 interleukin 18
IL1A interleukin 1, alpha
IL1B interleukin 1, beta
IL1RN interleukin 1 receptor antagonist
IL2 interleukin 2
IL21 interleukin 21
IL2RA interleukin 2 receptor, alpha
IL33 interleukin 33
IL33R interleukin 33 receptor
IL4 interleukin 4
IL4R interleukin 4 receptor
IL6 interleukin 6
ILK integrin-linked kinase
INHA inhibin, alpha
INHBB inhibin, beta B
IQSEC1 IQ motif and Sec7 domain 1
IRAK1 interleukin-1 receptor-associated kinase 1
IRF6 interferon regulatory factor 6
IRF8 interferon regulatory factor 8
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
JAK1 Janus kinase 1
JAK2 Janus kinase 2
JAK3 Janus kinase 3
JUNB jun B proto-oncogene
KANK1 KN motif and ankyrin repeat domains 1
KCNE1 potassium channel, voltage gated subfamily E regulatory beta subunit 1
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2
KCNMB2 potassium channel subfamily M regulatory beta subunit 2
KDR kinase insert domain receptor
KIAA0141 KIAA0141
KIF16B kinesin family member 16B
KISS1 KiSS-1 metastasis-suppressor
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KLK2 kallikrein-related peptidase 2
KLK3 kallikrein-related peptidase 3
KLRC1 killer cell lectin-like receptor subfamily C, member 1
KLRC2 killer cell lectin-like receptor subfamily C, member 2
KLRK1 killer cell lectin-like receptor subfamily K, member 1
KMT2E lysine (K)-specific methyltransferase 2E
KRAS Kirsten rat sarcoma viral oncogene homolog
KRT19 keratin 19, type I
KRT20 keratin 20, type I
KRT7 keratin 7, type II
LAMA1 laminin, alpha 1
LAMC1 laminin, gamma 1 (formerly LAMB2)
LCN2 lipocalin 2
LDHB lactate dehydrogenase B
LDHC lactate dehydrogenase C
LDHD lactate dehydrogenase D
LDLR low density lipoprotein receptor
LEP leptin
LEPR leptin receptor
LGALS3 lectin, galactoside-binding, soluble, 3
LGR5 leucine-rich repeat containing G protein-coupled receptor 5
LIG1 ligase I, DNA, ATP-dependent
LILRB2 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2
LIPE lipase, hormone-sensitive
LRP5 low density lipoprotein receptor-related protein 5
LTBP2 latent transforming growth factor beta binding protein 2
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast)
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog
MAFA v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog A
MAG myelin associated glycoprotein
MAGED4B melanoma antigen family D4B
MAP3K12 mitogen-activated protein kinase kinase kinase 12
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4
MAPK9 mitogen-activated protein kinase 9
MAPT microtubule-associated protein tau
MARC1 mitochondrial amidoxime reducing component 1
MARC2 mitochondrial amidoxime reducing component 2
MARK1 MAP/microtubule affinity-regulating kinase 1
MB myoglobin
MBL2 mannose-binding lectin (protein C) 2, soluble
MC4R melanocortin 4 receptor
MCHR1 melanin-concentrating hormone receptor 1
MCL1 myeloid cell leukemia 1
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MECOM MDS1 and EVI1 complex locus
MET MET proto-oncogene, receptor tyrosine kinase
MGMT O-6-methylguanine-DNA methyltransferase
MICA MHC class I polypeptide-related sequence A
MIP major intrinsic protein of lens fiber
MIR1-1 microRNA 1-1
MIR126 microRNA 126
MIR133A1 microRNA 133a-1
MIR133A2 microRNA 133a-2
MIR133B microRNA 133b
MIR140 microRNA 140
MIR144 microRNA 144
MIR155 microRNA 155
MIR15A microRNA 15a
MIR195 microRNA 195
MIR203A microRNA 203a
MIR206 microRNA 206
MIR221 microRNA 221
MIR23A microRNA 23a
MIR335 microRNA 335
MIRLET7A1 microRNA let-7a-1
MKI67 marker of proliferation Ki-67
MLANA melan-A
MLH1 mutL homolog 1
MLH3 mutL homolog 3
MMD monocyte to macrophage differentiation-associated
MMP11 matrix metallopeptidase 11
MMP2 matrix metallopeptidase 2
MMP3 matrix metallopeptidase 3
MMP7 matrix metallopeptidase 7
MMP9 matrix metallopeptidase 9
MPG N-methylpurine-DNA glycosylase
MPL MPL proto-oncogene, thrombopoietin receptor
MPZ myelin protein zero
MRE11A MRE11 meiotic recombination 11 homolog A (S. cerevisiae)
MS4A1 membrane-spanning 4-domains, subfamily A, member 1
MSMB microseminoprotein, beta-
MSTN myostatin
MTAP methylthioadenosine phosphorylase
MTDH metadherin
MTHFD1 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MTRR 5-methyltetrahydrofolate-homocysteine methyltransferase reductase
MUC1 mucin 1, cell surface associated
MUC16 mucin 16, cell surface associated
MUC4 mucin 4, cell surface associated
MUC5AC mucin 5AC, oligomeric mucus/gel-forming
MVK mevalonate kinase
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYD88 myeloid differentiation primary response 88
MYO15A myosin XVA
MYOC myocilin, trabecular meshwork inducible glucocorticoid response
MYPN myopalladin
NCAM1 neural cell adhesion molecule 1
NCF2 neutrophil cytosolic factor 2
NCOA3 nuclear receptor coactivator 3
NDUFV2 NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa
NES nestin
NET1 neuroepithelial cell transforming 1
NF1 neurofibromin 1
NFE2L2 nuclear factor, erythroid 2-like 2
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NGF nerve growth factor (beta polypeptide)
NKX2-1 NK2 homeobox 1
NLGN1 neuroligin 1
NME1 NME/NM23 nucleoside diphosphate kinase 1
NNMT nicotinamide N-methyltransferase
NOS1 nitric oxide synthase 1 (neuronal)
NOS1AP nitric oxide synthase 1 (neuronal) adaptor protein
NOS3 nitric oxide synthase 3 (endothelial cell)
NOTCH1 notch 1
NOTCH3 notch 3
NPPB natriuretic peptide B
NPR1 natriuretic peptide receptor 1
NPRL2 nitrogen permease regulator-like 2 (S. cerevisiae)
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NR4A2 nuclear receptor subfamily 4, group A, member 2
NRG1 neuregulin 1
NRP1 neuropilin 1
NUCLEOLIN nucleolin multifunctional protein
NUMB numb homolog (Drosophila)
OGT O-linked N-acetylglucosamine (GlcNAc) transferase
OPA1 optic atrophy 1 (autosomal dominant)
OPRK1 opioid receptor, kappa 1
ORAI1 ORAI calcium release-activated calcium modulator 1
OSMR oncostatin M receptor
OXTR oxytocin receptor
P2RX7 purinergic receptor P2X, ligand gated ion channel, 7
P2RY12 purinergic receptor P2Y, G-protein coupled, 12
PA2G4 proliferation-associated 2G4, 38kDa
PAH phenylalanine hydroxylase
PAPPA pregnancy-associated plasma protein A, pappalysin 1
PAWR PRKC, apoptosis, WT1, regulator
PAX5 paired box 5
PAX6 paired box 6
PCDH19 protocadherin 19
PCNA proliferating cell nuclear antigen
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor)
PDE7B phosphodiesterase 7B
PDGFA platelet-derived growth factor alpha polypeptide
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PDGFRB platelet-derived growth factor receptor, beta polypeptide
PDHA1 pyruvate dehydrogenase (lipoamide) alpha 1
PDIA2 protein disulfide isomerase family A, member 2
PDK1 pyruvate dehydrogenase kinase, isozyme 1
PDX1 pancreatic and duodenal homeobox 1
PEBP1 phosphatidylethanolamine binding protein 1
PELP1 proline, glutamate and leucine rich protein 1
PER2 period circadian clock 2
PGM1 phosphoglucomutase 1
PGR progesterone receptor
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
PIM1 Pim-1 proto-oncogene, serine/threonine kinase
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1
PINK1 PTEN induced putative kinase 1
PLA2G6 phospholipase A2, group VI (cytosolic, calcium-independent)
PLAT plasminogen activator, tissue
PLAU plasminogen activator, urokinase
PLAUR plasminogen activator, urokinase receptor
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific)
PLD2 phospholipase D2
PLG plasminogen
PLSCR1 phospholipid scramblase 1
PML promyelocytic leukemia
POLG polymerase (DNA directed), gamma
PON1 paraoxonase 1
PON2 paraoxonase 2
PPARA peroxisome proliferator-activated receptor alpha
PPARG peroxisome proliferator-activated receptor gamma
PPP2CA protein phosphatase 2, catalytic subunit, alpha isozyme
PPP2R2B protein phosphatase 2, regulatory subunit B, beta
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform
PRAME preferentially expressed antigen in melanoma
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
PRKCQ protein kinase C, theta
PRKD1 protein kinase D1
PRL prolactin
PRLR prolactin receptor
PRNP prion protein
PROM1 prominin 1
PROP1 PROP paired-like homeobox 1
PRSS1 protease, serine, 1 (trypsin 1)
PRSS2 protease, serine, 2 (trypsin 2)
PSEN1 presenilin 1
PSG2 pregnancy specific beta-1-glycoprotein 2
PSIP1 PC4 and SFRS1 interacting protein 1
PSMA6 proteasome (prosome, macropain) subunit, alpha type, 6
PSMB9 proteasome (prosome, macropain) subunit, beta type, 9
PSMD9 proteasome (prosome, macropain) 26S subunit, non-ATPase, 9
PTEN phosphatase and tensin homolog
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTK2 protein tyrosine kinase 2
PTP4A3 protein tyrosine phosphatase type IVA, member 3
PTPN1 protein tyrosine phosphatase, non-receptor type 1
PTPN11 protein tyrosine phosphatase, non-receptor type 11
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
PTPRE protein tyrosine phosphatase, receptor type, E
PTX3 pentraxin 3, long
PVR poliovirus receptor
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
RAD50 RAD50 homolog (S. cerevisiae)
RAD51 RAD51 recombinase
RAD51D RAD51 paralog D
RAD9A RAD9 homolog A (S. pombe)
RAI1 retinoic acid induced 1
RAPGEF4 Rap guanine nucleotide exchange factor (GEF) 4
RASGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated)
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RB1 retinoblastoma 1
RBFOX2 RNA binding protein, fox-1 homolog (C. elegans) 2
RBL2 retinoblastoma-like 2
RDH5 retinol dehydrogenase 5 (11-cis/9-cis)
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
RHCE Rh blood group, CcEe antigens
RHD Rh blood group, D antigen
RHOA ras homolog family member A
RHOB ras homolog family member B
RNASEL ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)
RNF11 ring finger protein 11
ROR1 receptor tyrosine kinase-like orphan receptor 1
RORA RAR-related orphan receptor A
ROS1 ROS proto-oncogene 1 , receptor tyrosine kinase
RPS6 ribosomal protein S6
RYR1 ryanodine receptor 1 (skeletal)
RYR2 ryanodine receptor 2 (cardiac)
S100B S100 calcium binding protein B
SCN1A sodium channel, voltage gated, type I alpha subunit
SCN5A sodium channel, voltage gated, type V alpha subunit
SDC1 syndecan 1
SELENBP1 selenium binding protein 1
SELP selectin P (granule membrane protein 140kDa, antigen CD62)
SERBP1 SERPINE1 mRNA binding protein 1
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SETX senataxin
SF3B1 splicing factor 3b, subunit 1, 155kDa
SFTPC surfactant protein C
SGK1 serum/glucocorticoid regulated kinase 1
SGK3 serum/glucocorticoid regulated kinase family, member 3
SIM1 single-minded family bHLH transcription factor 1
SIX1 SIX homeobox 1
SIX5 SIX homeobox 5
SLC16A13 solute carrier family 16, member 13
SLC17A1 solute carrier family 17 (organic anion transporter), member 1
SLC22A12 solute carrier family 22 (organic anion/urate transporter), member 12
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
SLC2A9 solute carrier family 2 (facilitated glucose transporter), member 9
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5
SLC9A3R2 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2
SMAD2 SMAD family member 2
SMAD4 SMAD family member 4
SMAD7 SMAD family member 7
SMARCB1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1
SMN1 survival of motor neuron 1, telomeric
SNAI1 snail family zinc finger 1
SOCS1 suppressor of cytokine signaling 1
SOD1 superoxide dismutase 1, soluble
SOST sclerostin
SPARC secreted protein, acidic, cysteine-rich (osteonectin)
SPINK5 serine peptidase inhibitor, Kazal type 5
SPN sialophorin
SPP1 secreted phosphoprotein 1
SRC SRC proto-oncogene, non-receptor tyrosine kinase
SRI sorcin
SSH1 slingshot protein phosphatase 1
ST14 suppression of tumorigenicity 14 (colon carcinoma)
STAT2 signal transducer and activator of transcription 2, 113kDa
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STOML2 stomatin (EPB72)-like 2
STYK1 serine/threonine/tyrosine kinase 1
SULT1A1 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
SYK spleen tyrosine kinase
SYN3 synapsin III
SYP synaptophysin
T T, brachyury homolog (mouse)
TAC3 tachykinin 3
TACC1 transforming, acidic coiled-coil containing protein 1
TACR1 tachykinin receptor 1
TANK TRAF family member-associated NFKB activator
TARDBP TAR DNA binding protein
TBXA2R thromboxane A2 receptor
TDGF1 teratocarcinoma-derived growth factor 1
TEK TEK tyrosine kinase, endothelial
TERC telomerase RNA component
TERF1 telomeric repeat binding factor (NIMA-interacting) 1
TERF2 telomeric repeat binding factor 2
TERT telomerase reverse transcriptase
TET1 tet methylcytosine dioxygenase 1
TF transferrin
TGFB1 transforming growth factor, beta 1
TGFB2 transforming growth factor, beta 2
TGFB3 transforming growth factor, beta 3
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TGM2 transglutaminase 2
TH tyrosine hydroxylase
THBS1 thrombospondin 1
THOC1 THO complex 1
TIMP2 TIMP metallopeptidase inhibitor 2
TLR2 toll-like receptor 2
TLR4 toll-like receptor 4
TLR9 toll-like receptor 9
TLX3 T-cell leukemia homeobox 3
TNC tenascin C
TNF tumor necrosis factor
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TNFSF13 tumor necrosis factor (ligand) superfamily, member 13
TNFSF13B tumor necrosis factor (ligand) superfamily, member 13b
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4
TNNC1 troponin C type 1 (slow)
TNNI1 troponin I type 1 (skeletal, slow)
TNS4 tensin 4
TOP2A topoisomerase (DNA) II alpha 170kDa
TOP3A topoisomerase (DNA) III alpha
TP53 tumor protein p53
TP73 tumor protein p73
TPH2 tryptophan hydroxylase 2
TRIM28 tripartite motif containing 28
TRPC1 transient receptor potential cation channel, subfamily C, member 1
TSPAN2 tetraspanin 2
TWIST1 twist family bHLH transcription factor 1
TYK2 tyrosine kinase 2
TYMP thymidine phosphorylase
TYMS thymidylate synthetase
UBE2C ubiquitin-conjugating enzyme E2C
UGT1A1 UDP glucuronosyltransferase 1 family, polypeptide A1
ULBP2 UL16 binding protein 2
ULK4 unc-51 like kinase 4
UNC79 unc-79 homolog (C. elegans)
VCAM1 vascular cell adhesion molecule 1
VCP valosin containing protein
VDAC1 voltage-dependent anion channel 1
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
VEGFA vascular endothelial growth factor A
VEGFC vascular endothelial growth factor C
VPS28 vacuolar protein sorting 28 homolog (S. cerevisiae)
VPS4A vacuolar protein sorting 4 homolog A (S. cerevisiae)
VPS4B vacuolar protein sorting 4 homolog B (S. cerevisiae)
VWF von Willebrand factor
WDR1 WD repeat domain 1
WFDC2 WAP four-disulfide core domain 2
WT1 Wilms tumor 1
WWOX WW domain containing oxidoreductase
XBP1 X-box binding protein 1
XPA xeroderma pigmentosum, complementation group A
XPO1 exportin 1
XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1
YBX1 Y box binding protein 1
ZAP70 zeta-chain (TCR) associated protein kinase 70kDa
ZBTB4 zinc finger and BTB domain containing 4
ZBTB7A zinc finger and BTB domain containing 7A
ZC3H12A zinc finger CCCH-type containing 12A
ZEB1 zinc finger E-box binding homeobox 1
ZFYVE9 zinc finger, FYVE domain containing 9