silicosis Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description A pneumoconiosis that is an inflammation and scarring of the uper lobes of the lungs causing nodular lesions resulting from inhalation of silica, quartz or slate particles. (Human Disease Ontology, DOID_10325)
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Genes

27 genes co-occuring with the biological term silicosis in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ACE angiotensin I converting enzyme
CXCL8 chemokine (C-X-C motif) ligand 8
CXCR2 chemokine (C-X-C motif) receptor 2
EGR1 early growth response 1
ENO2 enolase 2 (gamma, neuronal)
FAS Fas cell surface death receptor
FASLG Fas ligand (TNF superfamily, member 6)
GSTP1 glutathione S-transferase pi 1
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HMOX1 heme oxygenase 1
IFNG interferon, gamma
IFNGR1 interferon gamma receptor 1
IL10 interleukin 10
IL12B interleukin 12B
IL18 interleukin 18
IL1A interleukin 1, alpha
IL1B interleukin 1, beta
IL1RN interleukin 1 receptor antagonist
IL4 interleukin 4
MUC16 mucin 16, cell surface associated
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NOS2 nitric oxide synthase 2, inducible
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin)
SFTPD surfactant protein D
TGFB1 transforming growth factor, beta 1
TNF tumor necrosis factor